{"id":"https://openalex.org/W3126621491","doi":"https://doi.org/10.1162/jocn_a_01685","title":"Contributions of Brain Function and Structure to Three Different Domains of Cognitive Control in Normal Aging","display_name":"Contributions of Brain Function and Structure to Three Different Domains of Cognitive Control in Normal Aging","publication_year":2021,"publication_date":"2021-02-07","ids":{"openalex":"https://openalex.org/W3126621491","doi":"https://doi.org/10.1162/jocn_a_01685","mag":"3126621491","pmid":"https://pubmed.ncbi.nlm.nih.gov/34375414"},"language":"en","primary_location":{"id":"doi:10.1162/jocn_a_01685","is_oa":false,"landing_page_url":"https://doi.org/10.1162/jocn_a_01685","pdf_url":null,"source":{"id":"https://openalex.org/S123144817","display_name":"Journal of Cognitive Neuroscience","issn_l":"0898-929X","issn":["0898-929X","1530-8898"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315718","host_organization_name":"The MIT Press","host_organization_lineage":["https://openalex.org/P4310315718"],"host_organization_lineage_names":["The MIT Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cognitive Neuroscience","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032122607","display_name":"Jenny Rieck","orcid":"https://orcid.org/0000-0002-3242-6407"},"institutions":[{"id":"https://openalex.org/I2802437833","display_name":"Baycrest Hospital","ror":"https://ror.org/03gp5b411","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2802437833"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Jenny R. Rieck","raw_affiliation_strings":["Rotman Research Institute at Baycrest"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rotman Research Institute at Baycrest","institution_ids":["https://openalex.org/I2802437833"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078308153","display_name":"Giulia Baracchini","orcid":"https://orcid.org/0000-0001-9198-2780"},"institutions":[{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Giulia Baracchini","raw_affiliation_strings":["McGill University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"McGill University","institution_ids":["https://openalex.org/I5023651"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111972689","display_name":"Cheryl L. Grady","orcid":null},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I2802437833","display_name":"Baycrest Hospital","ror":"https://ror.org/03gp5b411","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2802437833"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Cheryl L. Grady","raw_affiliation_strings":["Rotman Research Institute at Baycrest","University of Toronto"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rotman Research Institute at Baycrest","institution_ids":["https://openalex.org/I2802437833"]},{"raw_affiliation_string":"University of Toronto","institution_ids":["https://openalex.org/I185261750"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5032122607"],"corresponding_institution_ids":["https://openalex.org/I2802437833"],"apc_list":null,"apc_paid":null,"fwci":1.5471,"has_fulltext":false,"cited_by_count":22,"citation_normalized_percentile":{"value":0.80706542,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"33","issue":"9","first_page":"1811","last_page":"1832"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10042","display_name":"Neural and Behavioral Psychology Studies","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9828000068664551,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/working-memory","display_name":"Working memory","score":0.8178606033325195},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.7480788826942444},{"id":"https://openalex.org/keywords/cognition","display_name":"Cognition","score":0.675482451915741},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.5827908515930176},{"id":"https://openalex.org/keywords/task","display_name":"Task (project management)","score":0.5147688388824463},{"id":"https://openalex.org/keywords/cognitive-psychology","display_name":"Cognitive psychology","score":0.5051921010017395},{"id":"https://openalex.org/keywords/task-switching","display_name":"Task switching","score":0.460768461227417},{"id":"https://openalex.org/keywords/functional-imaging","display_name":"Functional imaging","score":0.43233582377433777},{"id":"https://openalex.org/keywords/developmental-psychology","display_name":"Developmental psychology","score":0.32253870368003845}],"concepts":[{"id":"https://openalex.org/C21963081","wikidata":"https://www.wikidata.org/wiki/Q11337567","display_name":"Working memory","level":3,"score":0.8178606033325195},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.7480788826942444},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.675482451915741},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5827908515930176},{"id":"https://openalex.org/C2780451532","wikidata":"https://www.wikidata.org/wiki/Q759676","display_name":"Task (project management)","level":2,"score":0.5147688388824463},{"id":"https://openalex.org/C180747234","wikidata":"https://www.wikidata.org/wiki/Q23373","display_name":"Cognitive psychology","level":1,"score":0.5051921010017395},{"id":"https://openalex.org/C93500599","wikidata":"https://www.wikidata.org/wiki/Q7687352","display_name":"Task switching","level":3,"score":0.460768461227417},{"id":"https://openalex.org/C182752723","wikidata":"https://www.wikidata.org/wiki/Q1474590","display_name":"Functional imaging","level":2,"score":0.43233582377433777},{"id":"https://openalex.org/C138496976","wikidata":"https://www.wikidata.org/wiki/Q175002","display_name":"Developmental psychology","level":1,"score":0.32253870368003845},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C187736073","wikidata":"https://www.wikidata.org/wiki/Q2920921","display_name":"Management","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001931","descriptor_name":"Brain Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001931","descriptor_name":"Brain Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001931","descriptor_name":"Brain Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003071","descriptor_name":"Cognition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003071","descriptor_name":"Cognition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003071","descriptor_name":"Cognition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008570","descriptor_name":"Memory, Short-Term","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008570","descriptor_name":"Memory, Short-Term","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008570","descriptor_name":"Memory, Short-Term","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011930","descriptor_name":"Reaction Time","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011930","descriptor_name":"Reaction Time","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011930","descriptor_name":"Reaction Time","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1162/jocn_a_01685","is_oa":false,"landing_page_url":"https://doi.org/10.1162/jocn_a_01685","pdf_url":null,"source":{"id":"https://openalex.org/S123144817","display_name":"Journal of Cognitive Neuroscience","issn_l":"0898-929X","issn":["0898-929X","1530-8898"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315718","host_organization_name":"The MIT Press","host_organization_lineage":["https://openalex.org/P4310315718"],"host_organization_lineage_names":["The MIT Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cognitive Neuroscience","raw_type":"journal-article"},{"id":"pmid:34375414","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34375414","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of cognitive neuroscience","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/8","score":0.44999998807907104,"display_name":"Decent work and economic growth"}],"awards":[{"id":"https://openalex.org/G2574543202","display_name":null,"funder_award_id":"MOP143311","funder_id":"https://openalex.org/F4320334506","funder_display_name":"Canadian Institutes of Health Research"}],"funders":[{"id":"https://openalex.org/F4320334506","display_name":"Canadian Institutes of Health Research","ror":"https://ror.org/01gavpb45"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":94,"referenced_works":["https://openalex.org/W1519428955","https://openalex.org/W1574216169","https://openalex.org/W1965086680","https://openalex.org/W1965957039","https://openalex.org/W1969512253","https://openalex.org/W1974288685","https://openalex.org/W1981449019","https://openalex.org/W1984187963","https://openalex.org/W1985995290","https://openalex.org/W1990999410","https://openalex.org/W1992814938","https://openalex.org/W1993787537","https://openalex.org/W1997809077","https://openalex.org/W2000133863","https://openalex.org/W2000697043","https://openalex.org/W2016954751","https://openalex.org/W2019930104","https://openalex.org/W2021869533","https://openalex.org/W2026157789","https://openalex.org/W2030016425","https://openalex.org/W2037358606","https://openalex.org/W2037629289","https://openalex.org/W2040034734","https://openalex.org/W2042974739","https://openalex.org/W2044106385","https://openalex.org/W2045597616","https://openalex.org/W2052825472","https://openalex.org/W2073309755","https://openalex.org/W2073680542","https://openalex.org/W2073850739","https://openalex.org/W2080624766","https://openalex.org/W2088958511","https://openalex.org/W2089030269","https://openalex.org/W2090813996","https://openalex.org/W2097487913","https://openalex.org/W2099549454","https://openalex.org/W2101135654","https://openalex.org/W2101800098","https://openalex.org/W2104163310","https://openalex.org/W2104434501","https://openalex.org/W2105942783","https://openalex.org/W2106848425","https://openalex.org/W2108452713","https://openalex.org/W2110208125","https://openalex.org/W2110579639","https://openalex.org/W2112005505","https://openalex.org/W2113142053","https://openalex.org/W2114293191","https://openalex.org/W2116344581","https://openalex.org/W2122215233","https://openalex.org/W2123440500","https://openalex.org/W2123814848","https://openalex.org/W2124517301","https://openalex.org/W2128539615","https://openalex.org/W2133903921","https://openalex.org/W2134248637","https://openalex.org/W2137689618","https://openalex.org/W2138270641","https://openalex.org/W2139581313","https://openalex.org/W2140205353","https://openalex.org/W2141302788","https://openalex.org/W2142059961","https://openalex.org/W2144364601","https://openalex.org/W2149621887","https://openalex.org/W2151436330","https://openalex.org/W2151669887","https://openalex.org/W2151721316","https://openalex.org/W2155857408","https://openalex.org/W2159580216","https://openalex.org/W2159744772","https://openalex.org/W2159872566","https://openalex.org/W2167893510","https://openalex.org/W2290282624","https://openalex.org/W2335994239","https://openalex.org/W2485041709","https://openalex.org/W2549669100","https://openalex.org/W2566910879","https://openalex.org/W2588471314","https://openalex.org/W2729603490","https://openalex.org/W2734757979","https://openalex.org/W2753727094","https://openalex.org/W2896204498","https://openalex.org/W2916754187","https://openalex.org/W2958516736","https://openalex.org/W2971074351","https://openalex.org/W2999634920","https://openalex.org/W3033577168","https://openalex.org/W3089416312","https://openalex.org/W4211063003","https://openalex.org/W4238879677","https://openalex.org/W4251032739","https://openalex.org/W4296295377","https://openalex.org/W6602197165","https://openalex.org/W6759679273"],"related_works":["https://openalex.org/W2008108590","https://openalex.org/W2004381721","https://openalex.org/W2119429930","https://openalex.org/W1986493088","https://openalex.org/W4236715829","https://openalex.org/W2969465553","https://openalex.org/W2589440624","https://openalex.org/W3045532604","https://openalex.org/W2017733648","https://openalex.org/W2084221118"],"abstract_inverted_index":{"Cognitive":[0],"control":[1,51,90,171],"involves":[2],"the":[3,54,71,137,231],"flexible":[4],"allocation":[5],"of":[6,25,88,133,139,179,207,216,230,234,246],"mental":[7],"resources":[8],"during":[9],"goal-directed":[10],"behavior":[11],"and":[12,20,28,34,61,78,96,115,123,143,174,218,227,237],"comprises":[13],"three":[14,107,127],"correlated":[15],"but":[16,212],"distinct":[17],"domains-inhibition,":[18],"shifting,":[19],"working":[21],"memory.":[22],"The":[23],"work":[24],"Don":[26],"Stuss":[27],"others":[29],"has":[30],"demonstrated":[31],"that":[32,188],"frontal":[33],"parietal":[35],"cortices":[36],"are":[37,66],"crucial":[38],"to":[39,58,93,121,146,151,181,209,240],"cognitive":[40,89,247],"control,":[41],"particularly":[42],"in":[43,81,91,119,159,166,184],"normal":[44],"aging,":[45,235],"which":[46],"is":[47],"characterized":[48],"by":[49],"reduced":[50],"mechanisms.":[52],"However,":[53],"structure-function":[55],"relationships":[56],"specific":[57],"each":[59,152],"domain":[60],"subsequent":[62],"impact":[63],"on":[64],"performance":[65,145],"not":[67],"well":[68],"understood.":[69],"In":[70],"current":[72],"study,":[73],"we":[74],"examined":[75],"both":[76],"age":[77,217],"individual":[79],"differences":[80,158],"functional":[82,147,160,200,210,241],"activity":[83,148,161,211,242],"associated":[84,156],"with":[85,157],"core":[86],"domains":[87,245],"relation":[92],"fronto-parietal":[94,134,170,191],"structure":[95,180,192,208,239],"task":[97,112,144,219],"performance.":[98,220],"Participants":[99],"(n":[100],"=":[101],"140,":[102],"aged":[103],"20-86":[104],"years)":[105],"completed":[106],"fMRI":[108],"tasks:":[109],"go/no-go":[110],"(inhibition),":[111],"switching":[113],"(shifting),":[114],"n-back":[116],"(working":[117],"memory),":[118],"addition":[120],"structural":[122],"diffusion":[124],"imaging.":[125],"All":[126],"tasks":[128],"engaged":[129],"a":[130,196,225],"common":[131,169],"set":[132],"regions;":[135],"however,":[136],"contributions":[138,178,233],"age,":[140],"brain":[141,185,238],"structure,":[142],"were":[149],"unique":[150],"domain.":[153],"Aging":[154],"was":[155],"for":[162,198],"all":[163],"tasks,":[164],"largely":[165],"regions":[167],"outside":[168],"regions.":[172],"Shifting":[173],"inhibition":[175],"showed":[176,204],"greater":[177],"overall":[182],"decreases":[183],"activity,":[186],"suggesting":[187],"more":[189],"intact":[190],"may":[193],"serve":[194],"as":[195],"scaffold":[197],"efficient":[199],"response.":[201],"Working":[202],"memory":[203],"no":[205],"contribution":[206],"had":[213],"strong":[214],"effects":[215],"Together,":[221],"these":[222],"results":[223],"provide":[224],"comprehensive":[226],"novel":[228],"examination":[229],"joint":[232],"performance,":[236],"across":[243],"multiple":[244],"control.":[248]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":4}],"updated_date":"2026-05-06T08:25:59.206177","created_date":"2025-10-10T00:00:00"}