{"id":"https://openalex.org/W2964284206","doi":"https://doi.org/10.1162/isal_a_00163","title":"A simplified model of chromatin dynamics drives differentiation process in Boolean models of GRN","display_name":"A simplified model of chromatin dynamics drives differentiation process in Boolean models of GRN","publication_year":2019,"publication_date":"2019-01-01","ids":{"openalex":"https://openalex.org/W2964284206","doi":"https://doi.org/10.1162/isal_a_00163","mag":"2964284206"},"language":"en","primary_location":{"id":"doi:10.1162/isal_a_00163","is_oa":true,"landing_page_url":"https://doi.org/10.1162/isal_a_00163","pdf_url":"https://www.mitpressjournals.org/doi/pdf/10.1162/isal_a_00163","source":{"id":"https://openalex.org/S4363608301","display_name":"The 2019 Conference on Artificial Life","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The 2019 Conference on Artificial Life","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.mitpressjournals.org/doi/pdf/10.1162/isal_a_00163","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030984151","display_name":"Michele Braccini","orcid":"https://orcid.org/0000-0002-2335-2514"},"institutions":[{"id":"https://openalex.org/I9360294","display_name":"University of Bologna","ror":"https://ror.org/01111rn36","country_code":"IT","type":"education","lineage":["https://openalex.org/I9360294"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Michele Braccini","raw_affiliation_strings":["Dept. of Computer Science and Engineering, Alma Mater Studiorum Universit\u00e0 di Bologna"],"affiliations":[{"raw_affiliation_string":"Dept. of Computer Science and Engineering, Alma Mater Studiorum Universit\u00e0 di Bologna","institution_ids":["https://openalex.org/I9360294"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045128977","display_name":"Andrea Roli","orcid":"https://orcid.org/0000-0001-9891-5441"},"institutions":[{"id":"https://openalex.org/I9360294","display_name":"University of Bologna","ror":"https://ror.org/01111rn36","country_code":"IT","type":"education","lineage":["https://openalex.org/I9360294"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Andrea Roli","raw_affiliation_strings":["Dept. of Computer Science and Engineering, Alma Mater Studiorum Universit\u00e0 di Bologna"],"affiliations":[{"raw_affiliation_string":"Dept. of Computer Science and Engineering, Alma Mater Studiorum Universit\u00e0 di Bologna","institution_ids":["https://openalex.org/I9360294"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007379202","display_name":"Marco Villani","orcid":"https://orcid.org/0000-0002-5991-5470"},"institutions":[{"id":"https://openalex.org/I122346577","display_name":"University of Modena and Reggio Emilia","ror":"https://ror.org/02d4c4y02","country_code":"IT","type":"education","lineage":["https://openalex.org/I122346577"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Marco Villani","raw_affiliation_strings":["Dept. of Physics, Informatics and Mathematics, Universit\u00e0 di Modena e Reggio Emilia"],"affiliations":[{"raw_affiliation_string":"Dept. of Physics, Informatics and Mathematics, Universit\u00e0 di Modena e Reggio Emilia","institution_ids":["https://openalex.org/I122346577"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019839016","display_name":"Sara Montagna","orcid":"https://orcid.org/0000-0001-5390-4319"},"institutions":[{"id":"https://openalex.org/I9360294","display_name":"University of Bologna","ror":"https://ror.org/01111rn36","country_code":"IT","type":"education","lineage":["https://openalex.org/I9360294"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Sara Montagna","raw_affiliation_strings":["Dept. of Computer Science and Engineering, Alma Mater Studiorum Universit\u00e0 di Bologna"],"affiliations":[{"raw_affiliation_string":"Dept. of Computer Science and Engineering, Alma Mater Studiorum Universit\u00e0 di Bologna","institution_ids":["https://openalex.org/I9360294"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035698777","display_name":"Roberto Serra","orcid":"https://orcid.org/0000-0002-1417-5106"},"institutions":[{"id":"https://openalex.org/I887064364","display_name":"University of Amsterdam","ror":"https://ror.org/04dkp9463","country_code":"NL","type":"education","lineage":["https://openalex.org/I887064364"]},{"id":"https://openalex.org/I55027601","display_name":"Netherlands Institute for Advanced Study in the Humanities and Social Sciences","ror":"https://ror.org/04z3wz653","country_code":"NL","type":"facility","lineage":["https://openalex.org/I1322597698","https://openalex.org/I55027601"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Roberto Serra","raw_affiliation_strings":["Institute for Advanced Study (IAS), University of Amsterdam"],"affiliations":[{"raw_affiliation_string":"Institute for Advanced Study (IAS), University of Amsterdam","institution_ids":["https://openalex.org/I55027601","https://openalex.org/I887064364"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5030984151"],"corresponding_institution_ids":["https://openalex.org/I9360294"],"apc_list":null,"apc_paid":null,"fwci":1.4987,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.81028571,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":96},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.9850000143051147,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.9850000143051147,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9775999784469604,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9610999822616577,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.716143786907196},{"id":"https://openalex.org/keywords/process","display_name":"Process (computing)","score":0.6487478017807007},{"id":"https://openalex.org/keywords/dynamics","display_name":"Dynamics (music)","score":0.5520105361938477},{"id":"https://openalex.org/keywords/boolean-function","display_name":"Boolean function","score":0.49310824275016785},{"id":"https://openalex.org/keywords/chromatin","display_name":"Chromatin","score":0.472115159034729},{"id":"https://openalex.org/keywords/boolean-network","display_name":"Boolean network","score":0.421043336391449},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.39750370383262634},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3381308913230896},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.1902812123298645},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.1019611656665802}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.716143786907196},{"id":"https://openalex.org/C98045186","wikidata":"https://www.wikidata.org/wiki/Q205663","display_name":"Process (computing)","level":2,"score":0.6487478017807007},{"id":"https://openalex.org/C145912823","wikidata":"https://www.wikidata.org/wiki/Q113558","display_name":"Dynamics (music)","level":2,"score":0.5520105361938477},{"id":"https://openalex.org/C187455244","wikidata":"https://www.wikidata.org/wiki/Q942353","display_name":"Boolean function","level":2,"score":0.49310824275016785},{"id":"https://openalex.org/C83640560","wikidata":"https://www.wikidata.org/wiki/Q180951","display_name":"Chromatin","level":3,"score":0.472115159034729},{"id":"https://openalex.org/C134444547","wikidata":"https://www.wikidata.org/wiki/Q585230","display_name":"Boolean network","level":3,"score":0.421043336391449},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.39750370383262634},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3381308913230896},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.1902812123298645},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1019611656665802},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.0},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1162/isal_a_00163","is_oa":true,"landing_page_url":"https://doi.org/10.1162/isal_a_00163","pdf_url":"https://www.mitpressjournals.org/doi/pdf/10.1162/isal_a_00163","source":{"id":"https://openalex.org/S4363608301","display_name":"The 2019 Conference on Artificial Life","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The 2019 Conference on Artificial Life","raw_type":"proceedings-article"},{"id":"pmh:oai:cris.unibo.it:11585/693154","is_oa":false,"landing_page_url":"http://hdl.handle.net/11585/693154","pdf_url":null,"source":{"id":"https://openalex.org/S4306402579","display_name":"Archivio istituzionale della ricerca (Alma Mater Studiorum Universit\u00e0 di Bologna)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210117483","host_organization_name":"Istituto di Ematologia di Bologna","host_organization_lineage":["https://openalex.org/I4210117483"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/conferenceObject"},{"id":"pmh:oai:iris.unimore.it:11380/1179498","is_oa":true,"landing_page_url":"http://hdl.handle.net/11380/1179498","pdf_url":null,"source":{"id":"https://openalex.org/S4306400718","display_name":"IRIS UNIMORE (University of Modena and Reggio Emilia)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I122346577","host_organization_name":"University of Modena and Reggio Emilia","host_organization_lineage":["https://openalex.org/I122346577"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/conferenceObject"},{"id":"pmh:oai:ora.uniurb.it:11576/2690169","is_oa":false,"landing_page_url":"http://hdl.handle.net/11576/2690169","pdf_url":null,"source":{"id":"https://openalex.org/S4377196377","display_name":"CINECA IRIS Institutional Research information system (University of Urbino)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I190397597","host_organization_name":"University of Urbino","host_organization_lineage":["https://openalex.org/I190397597"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/conferenceObject"}],"best_oa_location":{"id":"doi:10.1162/isal_a_00163","is_oa":true,"landing_page_url":"https://doi.org/10.1162/isal_a_00163","pdf_url":"https://www.mitpressjournals.org/doi/pdf/10.1162/isal_a_00163","source":{"id":"https://openalex.org/S4363608301","display_name":"The 2019 Conference on Artificial Life","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The 2019 Conference on Artificial Life","raw_type":"proceedings-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2964284206.pdf","grobid_xml":"https://content.openalex.org/works/W2964284206.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2918709778","https://openalex.org/W2105128170","https://openalex.org/W1991822629","https://openalex.org/W2162432446","https://openalex.org/W3141532631","https://openalex.org/W1975961967","https://openalex.org/W1979056074","https://openalex.org/W52722086","https://openalex.org/W2558644562","https://openalex.org/W1567571871"],"abstract_inverted_index":{"Cellular":[0],"types":[1],"of":[2,9],"multicellular":[3],"organisms":[4],"are":[5],"the":[6,19],"stable":[7],"results":[8],"complex":[10],"intertwined":[11],"processes":[12],"that":[13],"occur":[14],"in":[15],"biological":[16],"cells.":[17],"Among":[18],"many":[20],"others,":[21],"chromatin":[22],"dynamics":[23],"significantly":[24],"contributes...":[25]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2020,"cited_by_count":2}],"updated_date":"2026-03-20T23:20:44.827607","created_date":"2025-10-10T00:00:00"}