{"id":"https://openalex.org/W2099633054","doi":"https://doi.org/10.1162/089976603762552924","title":"Reliability of Spike Timing Is a General Property of Spiking Model Neurons","display_name":"Reliability of Spike Timing Is a General Property of Spiking Model Neurons","publication_year":2003,"publication_date":"2003-02-01","ids":{"openalex":"https://openalex.org/W2099633054","doi":"https://doi.org/10.1162/089976603762552924","mag":"2099633054","pmid":"https://pubmed.ncbi.nlm.nih.gov/12590808"},"language":"en","primary_location":{"id":"doi:10.1162/089976603762552924","is_oa":false,"landing_page_url":"https://doi.org/10.1162/089976603762552924","pdf_url":null,"source":{"id":"https://openalex.org/S207023548","display_name":"Neural Computation","issn_l":"0899-7667","issn":["0899-7667","1530-888X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315718","host_organization_name":"The MIT Press","host_organization_lineage":["https://openalex.org/P4310315718"],"host_organization_lineage_names":["The MIT Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neural Computation","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076201697","display_name":"Romain Brette","orcid":"https://orcid.org/0000-0003-0110-1623"},"institutions":[{"id":"https://openalex.org/I4210150889","display_name":"Center for MathematicaL studies and their Applications","ror":"https://ror.org/05pabaz56","country_code":"FR","type":"facility","lineage":["https://openalex.org/I11559806","https://openalex.org/I1294671590","https://openalex.org/I277688954","https://openalex.org/I4210141950","https://openalex.org/I4210150889"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"funder","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I11559806","display_name":"\u00c9cole Normale Sup\u00e9rieure Paris-Saclay","ror":"https://ror.org/00hx6zz33","country_code":"FR","type":"education","lineage":["https://openalex.org/I11559806","https://openalex.org/I277688954"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Romain Brette","raw_affiliation_strings":["Centre de Math\u00e9matiques et de Leurs Applications, Ecole Normale Sup\u00e9rieurede Cachan, 94230 Cachan, France, and INSERM U483, Universit\u00e9 Pierre et Marie Curie, 75005 Paris, France,"],"affiliations":[{"raw_affiliation_string":"Centre de Math\u00e9matiques et de Leurs Applications, Ecole Normale Sup\u00e9rieurede Cachan, 94230 Cachan, France, and INSERM U483, Universit\u00e9 Pierre et Marie Curie, 75005 Paris, France,","institution_ids":["https://openalex.org/I11559806","https://openalex.org/I154526488","https://openalex.org/I4210150889","https://openalex.org/I39804081"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5060496993","display_name":"Emmanuel Guigon","orcid":"https://orcid.org/0000-0002-4506-701X"},"institutions":[{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"funder","lineage":["https://openalex.org/I154526488"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Emmanuel Guigon","raw_affiliation_strings":["INSERM U483, Universit\u00e9 Pierre et Marie Curie, 75005 Paris, France"],"affiliations":[{"raw_affiliation_string":"INSERM U483, Universit\u00e9 Pierre et Marie Curie, 75005 Paris, France","institution_ids":["https://openalex.org/I39804081","https://openalex.org/I154526488"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5076201697"],"corresponding_institution_ids":["https://openalex.org/I11559806","https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210150889"],"apc_list":null,"apc_paid":null,"fwci":2.4059,"has_fulltext":false,"cited_by_count":61,"citation_normalized_percentile":{"value":0.87786337,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"15","issue":"2","first_page":"279","last_page":"308"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10502","display_name":"Advanced Memory and Neural Computing","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11513","display_name":"stochastic dynamics and bifurcation","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/3109","display_name":"Statistical and Nonlinear Physics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/aperiodic-graph","display_name":"Aperiodic graph","score":0.8743268251419067},{"id":"https://openalex.org/keywords/spike","display_name":"Spike (software development)","score":0.6836909055709839},{"id":"https://openalex.org/keywords/noise","display_name":"Noise (video)","score":0.6196495294570923},{"id":"https://openalex.org/keywords/constant","display_name":"Constant (computer programming)","score":0.5678368806838989},{"id":"https://openalex.org/keywords/statistical-physics","display_name":"Statistical physics","score":0.500112771987915},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.4935563802719116},{"id":"https://openalex.org/keywords/nonlinear-system","display_name":"Nonlinear system","score":0.45450741052627563},{"id":"https://openalex.org/keywords/spike-train","display_name":"Spike train","score":0.4511805772781372},{"id":"https://openalex.org/keywords/time-constant","display_name":"Time constant","score":0.4497503936290741},{"id":"https://openalex.org/keywords/variance","display_name":"Variance (accounting)","score":0.44166314601898193},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.44109079241752625},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.43257713317871094},{"id":"https://openalex.org/keywords/property","display_name":"Property (philosophy)","score":0.42044830322265625},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.39099574089050293},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.3258984088897705},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.17702960968017578},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.14338400959968567},{"id":"https://openalex.org/keywords/combinatorics","display_name":"Combinatorics","score":0.09300285577774048}],"concepts":[{"id":"https://openalex.org/C104247578","wikidata":"https://www.wikidata.org/wiki/Q4779368","display_name":"Aperiodic graph","level":2,"score":0.8743268251419067},{"id":"https://openalex.org/C2781390188","wikidata":"https://www.wikidata.org/wiki/Q25203449","display_name":"Spike (software development)","level":2,"score":0.6836909055709839},{"id":"https://openalex.org/C99498987","wikidata":"https://www.wikidata.org/wiki/Q2210247","display_name":"Noise (video)","level":3,"score":0.6196495294570923},{"id":"https://openalex.org/C2777027219","wikidata":"https://www.wikidata.org/wiki/Q1284190","display_name":"Constant (computer programming)","level":2,"score":0.5678368806838989},{"id":"https://openalex.org/C121864883","wikidata":"https://www.wikidata.org/wiki/Q677916","display_name":"Statistical physics","level":1,"score":0.500112771987915},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.4935563802719116},{"id":"https://openalex.org/C158622935","wikidata":"https://www.wikidata.org/wiki/Q660848","display_name":"Nonlinear system","level":2,"score":0.45450741052627563},{"id":"https://openalex.org/C2909946758","wikidata":"https://www.wikidata.org/wiki/Q194277","display_name":"Spike train","level":3,"score":0.4511805772781372},{"id":"https://openalex.org/C81370116","wikidata":"https://www.wikidata.org/wiki/Q1335249","display_name":"Time constant","level":2,"score":0.4497503936290741},{"id":"https://openalex.org/C196083921","wikidata":"https://www.wikidata.org/wiki/Q7915758","display_name":"Variance (accounting)","level":2,"score":0.44166314601898193},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.44109079241752625},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.43257713317871094},{"id":"https://openalex.org/C189950617","wikidata":"https://www.wikidata.org/wiki/Q937228","display_name":"Property (philosophy)","level":2,"score":0.42044830322265625},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.39099574089050293},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.3258984088897705},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.17702960968017578},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.14338400959968567},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.09300285577774048},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C121955636","wikidata":"https://www.wikidata.org/wiki/Q4116214","display_name":"Accounting","level":1,"score":0.0},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.0},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C115903868","wikidata":"https://www.wikidata.org/wiki/Q80993","display_name":"Software engineering","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000200","descriptor_name":"Action Potentials","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000200","descriptor_name":"Action Potentials","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000200","descriptor_name":"Action Potentials","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1162/089976603762552924","is_oa":false,"landing_page_url":"https://doi.org/10.1162/089976603762552924","pdf_url":null,"source":{"id":"https://openalex.org/S207023548","display_name":"Neural Computation","issn_l":"0899-7667","issn":["0899-7667","1530-888X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315718","host_organization_name":"The MIT Press","host_organization_lineage":["https://openalex.org/P4310315718"],"host_organization_lineage_names":["The MIT Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neural Computation","raw_type":"journal-article"},{"id":"pmid:12590808","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12590808","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neural computation","raw_type":null},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.4.1754","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.4.1754","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.snv.jussieu.fr/brette/papers/BG03.pdf","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":38,"referenced_works":["https://openalex.org/W30649988","https://openalex.org/W136640337","https://openalex.org/W1583666889","https://openalex.org/W1593079125","https://openalex.org/W1594210692","https://openalex.org/W1694767778","https://openalex.org/W1843946745","https://openalex.org/W1876386593","https://openalex.org/W1947144830","https://openalex.org/W2002298833","https://openalex.org/W2010181515","https://openalex.org/W2011287669","https://openalex.org/W2029342452","https://openalex.org/W2040237110","https://openalex.org/W2049109809","https://openalex.org/W2050702978","https://openalex.org/W2061543953","https://openalex.org/W2062899906","https://openalex.org/W2067265108","https://openalex.org/W2067534449","https://openalex.org/W2072016696","https://openalex.org/W2074942478","https://openalex.org/W2076656952","https://openalex.org/W2082217115","https://openalex.org/W2082256896","https://openalex.org/W2090756128","https://openalex.org/W2100860578","https://openalex.org/W2112661761","https://openalex.org/W2117509237","https://openalex.org/W2119757675","https://openalex.org/W2139789458","https://openalex.org/W2144536052","https://openalex.org/W2159982751","https://openalex.org/W2163598552","https://openalex.org/W2327812242","https://openalex.org/W2418343484","https://openalex.org/W2577608236","https://openalex.org/W3217350819"],"related_works":["https://openalex.org/W2005561889","https://openalex.org/W2549307543","https://openalex.org/W2017444605","https://openalex.org/W2365061045","https://openalex.org/W2020928608","https://openalex.org/W2266505046","https://openalex.org/W4214654710","https://openalex.org/W2099633054","https://openalex.org/W2134430423","https://openalex.org/W2128949090"],"abstract_inverted_index":{"The":[0],"responses":[1,64,89],"of":[2,52,60,110,149],"neurons":[3],"to":[4,34,49,67,81,131],"time-varying":[5],"injected":[6],"currents":[7,55,159],"are":[8,138],"reproducible":[9,69,135],"on":[10,93],"a":[11,18,35,82,107,154],"trial-by-trial":[12],"basis":[13],"in":[14,25,38,70,116,143],"vitro,":[15],"but":[16],"when":[17],"constant":[19],"current":[20],"is":[21,42,47],"injected,":[22],"small":[23],"variances":[24],"interspike":[26],"intervals":[27],"across":[28],"trials":[29],"add":[30],"up,":[31],"eventually":[32],"leading":[33],"high":[36],"variance":[37],"spike":[39],"timing.":[40],"It":[41],"unclear":[43],"whether":[44],"this":[45],"difference":[46],"due":[48],"the":[50,53,57,61,94,118,150,162],"nature":[51],"input":[54],"or":[56,86],"intrinsic":[58],"properties":[59],"neurons.":[62],"Neuron":[63],"can":[65,75,90],"fail":[66],"be":[68],"two":[71],"ways:":[72],"dynamical":[73],"noise":[74],"accumulate":[76],"over":[77,84],"time":[78],"and":[79,102,146],"lead":[80],"desynchronization":[83],"trials,":[85],"several":[87],"stable":[88,139],"exist,":[91],"depending":[92],"initial":[95,144],"condition.":[96],"Here":[97],"we":[98],"show,":[99],"through":[100],"simulations":[101],"theoretical":[103,155],"considerations,":[104],"that":[105,160],"for":[106,157],"general":[108],"class":[109],"spiking":[111,126],"neuron":[112],"models,":[113,127],"which":[114,137],"includes,":[115],"particular,":[117],"leaky":[119],"integrate-and-fire":[120],"model":[121],"as":[122,124],"well":[123],"nonlinear":[125],"aperiodic":[128,158],"currents,":[129,133],"contrary":[130],"periodic":[132],"induce":[134],"responses,":[136],"under":[140],"noise,":[141],"change":[142],"conditions":[145],"deterministic":[147],"perturbations":[148],"input.":[151],"We":[152],"provide":[153],"explanation":[156],"cross":[161],"threshold.":[163]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":4},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":4}],"updated_date":"2026-04-04T16:13:02.066488","created_date":"2025-10-10T00:00:00"}