{"id":"https://openalex.org/W3135639762","doi":"https://doi.org/10.1155/2021/6676692","title":"Identification of Five Immune-Related lncRNAs Predicting Survival and Tumor Microenvironment Characteristics in Breast Cancer","display_name":"Identification of Five Immune-Related lncRNAs Predicting Survival and Tumor Microenvironment Characteristics in Breast Cancer","publication_year":2021,"publication_date":"2021-02-27","ids":{"openalex":"https://openalex.org/W3135639762","doi":"https://doi.org/10.1155/2021/6676692","mag":"3135639762","pmid":"https://pubmed.ncbi.nlm.nih.gov/33727952"},"language":"en","primary_location":{"id":"doi:10.1155/2021/6676692","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2021/6676692","pdf_url":"https://downloads.hindawi.com/journals/cmmm/2021/6676692.pdf","source":{"id":"https://openalex.org/S36980176","display_name":"Computational and Mathematical Methods in Medicine","issn_l":"1748-670X","issn":["1748-670X","1748-6718"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869"],"host_organization_lineage_names":["Hindawi Publishing Corporation"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computational and Mathematical Methods in Medicine","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://downloads.hindawi.com/journals/cmmm/2021/6676692.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5002656065","display_name":"Ran Xiao","orcid":"https://orcid.org/0000-0001-9502-7211"},"institutions":[{"id":"https://openalex.org/I4210156804","display_name":"First Affiliated Hospital of Zhengzhou University","ror":"https://ror.org/056swr059","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210156804"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ran Xiao","raw_affiliation_strings":["Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China"],"raw_orcid":"https://orcid.org/0000-0001-9502-7211","affiliations":[{"raw_affiliation_string":"Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China","institution_ids":["https://openalex.org/I4210156804"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011506864","display_name":"Meng Yang","orcid":"https://orcid.org/0000-0003-0474-128X"},"institutions":[{"id":"https://openalex.org/I4210156804","display_name":"First Affiliated Hospital of Zhengzhou University","ror":"https://ror.org/056swr059","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210156804"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Meng Yang","raw_affiliation_strings":["Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China","institution_ids":["https://openalex.org/I4210156804"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101626241","display_name":"Yuanyuan Tan","orcid":"https://orcid.org/0000-0002-1081-664X"},"institutions":[{"id":"https://openalex.org/I4210149496","display_name":"Zhengzhou People's Hospital","ror":"https://ror.org/04tgrpw60","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210149496"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuanyuan Tan","raw_affiliation_strings":["Department of Cardiology, The 7th People\u2019s Hospital of Zhengzhou, Zhengzhou 450006, China","Department of Cardiology, The 7th People's Hospital of Zhengzhou, Zhengzhou 450006, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, The 7th People\u2019s Hospital of Zhengzhou, Zhengzhou 450006, China","institution_ids":["https://openalex.org/I4210149496"]},{"raw_affiliation_string":"Department of Cardiology, The 7th People's Hospital of Zhengzhou, Zhengzhou 450006, China","institution_ids":["https://openalex.org/I4210149496"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113119136","display_name":"Rumeng Ding","orcid":null},"institutions":[{"id":"https://openalex.org/I4210156804","display_name":"First Affiliated Hospital of Zhengzhou University","ror":"https://ror.org/056swr059","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210156804"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Rumeng Ding","raw_affiliation_strings":["Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China","institution_ids":["https://openalex.org/I4210156804"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049586949","display_name":"Duolu Li","orcid":null},"institutions":[{"id":"https://openalex.org/I4210156804","display_name":"First Affiliated Hospital of Zhengzhou University","ror":"https://ror.org/056swr059","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210156804"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Duolu Li","raw_affiliation_strings":["Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China"],"raw_orcid":"https://orcid.org/0000-0001-8410-359X","affiliations":[{"raw_affiliation_string":"Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China","institution_ids":["https://openalex.org/I4210156804"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5049586949"],"corresponding_institution_ids":["https://openalex.org/I4210156804"],"apc_list":{"value":2100,"currency":"USD","value_usd":2100},"apc_paid":{"value":2100,"currency":"USD","value_usd":2100},"fwci":1.8562,"has_fulltext":true,"cited_by_count":21,"citation_normalized_percentile":{"value":0.85139751,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"2021","issue":null,"first_page":"1","last_page":"12"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.9890000224113464,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11316","display_name":"Mycobacterium research and diagnosis","score":0.9799000024795532,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/breast-cancer","display_name":"Breast cancer","score":0.7128822207450867},{"id":"https://openalex.org/keywords/immune-system","display_name":"Immune system","score":0.6730600595474243},{"id":"https://openalex.org/keywords/oncology","display_name":"Oncology","score":0.5848087072372437},{"id":"https://openalex.org/keywords/proportional-hazards-model","display_name":"Proportional hazards model","score":0.5730487704277039},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.5580494403839111},{"id":"https://openalex.org/keywords/tumor-microenvironment","display_name":"Tumor microenvironment","score":0.4954022169113159},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.46906778216362},{"id":"https://openalex.org/keywords/survival-analysis","display_name":"Survival analysis","score":0.4633263945579529},{"id":"https://openalex.org/keywords/long-non-coding-rna","display_name":"Long non-coding RNA","score":0.42664068937301636},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.3892481327056885},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.3559029996395111},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.3364008665084839},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.31193429231643677},{"id":"https://openalex.org/keywords/immunology","display_name":"Immunology","score":0.28198742866516113},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.16906586289405823},{"id":"https://openalex.org/keywords/downregulation-and-upregulation","display_name":"Downregulation and upregulation","score":0.14429113268852234}],"concepts":[{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.7128822207450867},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6730600595474243},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5848087072372437},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.5730487704277039},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5580494403839111},{"id":"https://openalex.org/C2776107976","wikidata":"https://www.wikidata.org/wiki/Q1786433","display_name":"Tumor microenvironment","level":3,"score":0.4954022169113159},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.46906778216362},{"id":"https://openalex.org/C10515644","wikidata":"https://www.wikidata.org/wiki/Q543310","display_name":"Survival analysis","level":2,"score":0.4633263945579529},{"id":"https://openalex.org/C62203573","wikidata":"https://www.wikidata.org/wiki/Q15087973","display_name":"Long non-coding RNA","level":4,"score":0.42664068937301636},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3892481327056885},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3559029996395111},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3364008665084839},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.31193429231643677},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.28198742866516113},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.16906586289405823},{"id":"https://openalex.org/C127561419","wikidata":"https://www.wikidata.org/wiki/Q224527","display_name":"Downregulation and upregulation","level":3,"score":0.14429113268852234}],"mesh":[{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006019","descriptor_name":"Glycolysis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006019","descriptor_name":"Glycolysis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006019","descriptor_name":"Glycolysis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006019","descriptor_name":"Glycolysis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006019","descriptor_name":"Glycolysis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006019","descriptor_name":"Glycolysis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010085","descriptor_name":"Oxidative Phosphorylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010085","descriptor_name":"Oxidative Phosphorylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010085","descriptor_name":"Oxidative Phosphorylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012334","descriptor_name":"RNA, Neoplasm","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012334","descriptor_name":"RNA, Neoplasm","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012334","descriptor_name":"RNA, Neoplasm","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012334","descriptor_name":"RNA, Neoplasm","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D012334","descriptor_name":"RNA, Neoplasm","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D012334","descriptor_name":"RNA, Neoplasm","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016016","descriptor_name":"Proportional Hazards Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016016","descriptor_name":"Proportional Hazards Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016016","descriptor_name":"Proportional Hazards Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016176","descriptor_name":"T-Lymphocyte Subsets","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016176","descriptor_name":"T-Lymphocyte Subsets","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016176","descriptor_name":"T-Lymphocyte Subsets","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016246","descriptor_name":"Lymphocytes, Tumor-Infiltrating","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016246","descriptor_name":"Lymphocytes, Tumor-Infiltrating","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016246","descriptor_name":"Lymphocytes, Tumor-Infiltrating","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016259","descriptor_name":"Genes, myc","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016259","descriptor_name":"Genes, myc","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016259","descriptor_name":"Genes, myc","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053208","descriptor_name":"Kaplan-Meier Estimate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053208","descriptor_name":"Kaplan-Meier Estimate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053208","descriptor_name":"Kaplan-Meier Estimate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059016","descriptor_name":"Tumor Microenvironment","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D059016","descriptor_name":"Tumor Microenvironment","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D059016","descriptor_name":"Tumor Microenvironment","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D059016","descriptor_name":"Tumor Microenvironment","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D059016","descriptor_name":"Tumor Microenvironment","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D059016","descriptor_name":"Tumor Microenvironment","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D062085","descriptor_name":"RNA, Long Noncoding","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D062085","descriptor_name":"RNA, Long Noncoding","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D062085","descriptor_name":"RNA, Long Noncoding","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D062085","descriptor_name":"RNA, Long Noncoding","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D062085","descriptor_name":"RNA, Long Noncoding","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D062085","descriptor_name":"RNA, Long Noncoding","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1155/2021/6676692","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2021/6676692","pdf_url":"https://downloads.hindawi.com/journals/cmmm/2021/6676692.pdf","source":{"id":"https://openalex.org/S36980176","display_name":"Computational and Mathematical Methods in Medicine","issn_l":"1748-670X","issn":["1748-670X","1748-6718"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869"],"host_organization_lineage_names":["Hindawi Publishing Corporation"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computational and Mathematical Methods in Medicine","raw_type":"journal-article"},{"id":"pmid:33727952","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33727952","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computational and mathematical methods in medicine","raw_type":null},{"id":"pmh:oai:doaj.org/article:106539e5da3147a0905c3567d72c0963","is_oa":false,"landing_page_url":"https://doaj.org/article/106539e5da3147a0905c3567d72c0963","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Computational and Mathematical Methods in Medicine, Vol 2021 (2021)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7937456","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7937456","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Comput Math Methods Med","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1155/2021/6676692","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2021/6676692","pdf_url":"https://downloads.hindawi.com/journals/cmmm/2021/6676692.pdf","source":{"id":"https://openalex.org/S36980176","display_name":"Computational and Mathematical Methods in Medicine","issn_l":"1748-670X","issn":["1748-670X","1748-6718"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869"],"host_organization_lineage_names":["Hindawi Publishing Corporation"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computational and Mathematical Methods in Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8700000047683716,"id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3135639762.pdf","grobid_xml":"https://content.openalex.org/works/W3135639762.grobid-xml"},"referenced_works_count":42,"referenced_works":["https://openalex.org/W1957438118","https://openalex.org/W2029919331","https://openalex.org/W2035252444","https://openalex.org/W2129375421","https://openalex.org/W2343471288","https://openalex.org/W2416900233","https://openalex.org/W2562493667","https://openalex.org/W2584855552","https://openalex.org/W2735717640","https://openalex.org/W2745196530","https://openalex.org/W2752658156","https://openalex.org/W2766084386","https://openalex.org/W2767211032","https://openalex.org/W2771978163","https://openalex.org/W2795382323","https://openalex.org/W2805884278","https://openalex.org/W2810118001","https://openalex.org/W2903856661","https://openalex.org/W2913062750","https://openalex.org/W2916763191","https://openalex.org/W2936066009","https://openalex.org/W2942233012","https://openalex.org/W2944633449","https://openalex.org/W2965266291","https://openalex.org/W2971451528","https://openalex.org/W2971701160","https://openalex.org/W2978810676","https://openalex.org/W2979291688","https://openalex.org/W2985141861","https://openalex.org/W2986044609","https://openalex.org/W2986967132","https://openalex.org/W3002658537","https://openalex.org/W3007076712","https://openalex.org/W3008008711","https://openalex.org/W3017191674","https://openalex.org/W3023029929","https://openalex.org/W3033918641","https://openalex.org/W3049515533","https://openalex.org/W3080863806","https://openalex.org/W3087220431","https://openalex.org/W3093077366","https://openalex.org/W3094705434"],"related_works":["https://openalex.org/W2797301068","https://openalex.org/W2010631330","https://openalex.org/W2006470775","https://openalex.org/W2581226876","https://openalex.org/W4225134093","https://openalex.org/W4380448775","https://openalex.org/W4380269519","https://openalex.org/W3136232645","https://openalex.org/W1554732404","https://openalex.org/W2026784993"],"abstract_inverted_index":{"A":[0],"common":[1],"cancer":[2,6,226,250],"in":[3,58,136,147,158,163,184,193],"females,":[4],"breast":[5,249],"(BRCA)":[7],"mortality":[8],"has":[9],"been":[10],"recently":[11],"reduced;":[12],"however,":[13],"the":[14,36,42,70,89,107,125,132,137,148,185,194,200,211,225,232,238,254,261],"prognosis":[15,90],"of":[16,38,80,91,127,202,231,256],"BRCA":[17,33,92,159,281],"patients":[18],"remains":[19],"poor.":[20],"This":[21],"study":[22],"attempted":[23],"to":[24,60,84,88,101,124,142,180,206,223,253],"develop":[25],"prognostic":[26,103,273],"immune-related":[27,75,104,128,244,266],"long":[28],"noncoding":[29],"RNAs":[30],"(lncRNAs)":[31],"for":[32,169,248,280],"and":[34,115,118,190,197,228,234,275],"identify":[35],"effects":[37],"these":[39],"lncRNAs":[40,66,76,105,267],"on":[41],"tumor":[43],"microenvironment":[44],"(TME).":[45],"Gene":[46,216],"expression":[47,156,201],"data":[48],"from":[49,69],"The":[50],"Cancer":[51],"Genome":[52],"Atlas":[53],"(TCGA)":[54],"database":[55,240],"were":[56,67,77,82,121,162],"collected":[57],"order":[59],"select":[61],"differentially":[62],"expressed":[63,183],"lncRNAs.":[64],"Immune-related":[65],"downloaded":[68],"ImmLnc":[71],"database,":[72],"where":[73],"316":[74],"identified,":[78],"12":[79],"which":[81],"found":[83,205],"be":[85,143,181,207,269],"significantly":[86,208],"related":[87,252],"patients.":[93,282],"Multivariate":[94],"cox":[95],"regression":[96],"analysis":[97,152,219],"was":[98,140,178,204,221],"then":[99],"applied":[100,222],"construct":[102],"as":[106,271],"risk":[108,129,246],"model,":[109],"including":[110],"C6orf99,":[111],"LINC00987,":[112],"SIAH2-AS1,":[113],"LINC01010,":[114],"ELOVL2-AS1.":[116],"High-risk":[117],"low-risk":[119,149,235],"groups":[120,212],"distinguished":[122],"according":[123],"median":[126],"scores.":[130],"Accordingly,":[131],"overall":[133],"survival":[134],"(OS)":[135],"high-risk":[138,233],"group":[139],"observed":[141],"shorter":[144],"than":[145],"that":[146,154,242,264],"group.":[150],"qRT-PCR":[151],"demonstrated":[153,241],"lncRNA":[155,176,245],"levels":[157],"cell":[160],"lines":[161],"basic":[164],"agreement":[165],"with":[166],"predictions":[167],"except":[168],"LINC00987.":[170],"By":[171],"validating":[172],"numerous":[173],"clinical":[174],"samples,":[175],"C6orf99":[177],"shown":[179],"highly":[182],"advanced":[186,195],"stage,":[187],"while":[188],"LINC01010":[189],"SIAH2-AS1":[191],"decreased":[192,209],"T-stage":[196],"M-stage.":[198],"Moreover,":[199],"LINC0098":[203],"among":[210],"(>50":[213],"years":[214],"old).":[215],"set":[217],"enrichment":[218],"(GSEA)":[220],"analyze":[224],"hallmarks":[227],"immunological":[229],"characteristics":[230],"groups.":[236],"Importantly,":[237],"TIMER":[239],"this":[243],"model":[247,274],"is":[251],"infiltration":[255],"immune":[257],"cells.":[258],"In":[259],"conclusion,":[260],"results":[262],"indicated":[263],"five":[265],"could":[268],"used":[270],"a":[272],"may":[276],"even":[277],"accelerate":[278],"immunotherapy":[279]},"counts_by_year":[{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":12},{"year":2021,"cited_by_count":2}],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2025-10-10T00:00:00"}