{"id":"https://openalex.org/W3117223433","doi":"https://doi.org/10.1155/2020/8899957","title":"A Crossover Comparison of the Sensitivity and the Specificity between BIS and AEP in Predicting Unconsciousness in General Anesthesia","display_name":"A Crossover Comparison of the Sensitivity and the Specificity between BIS and AEP in Predicting Unconsciousness in General Anesthesia","publication_year":2020,"publication_date":"2020-12-28","ids":{"openalex":"https://openalex.org/W3117223433","doi":"https://doi.org/10.1155/2020/8899957","mag":"3117223433"},"language":"en","primary_location":{"id":"doi:10.1155/2020/8899957","is_oa":true,"landing_page_url":"http://doi.org/10.1155/2020/8899957","pdf_url":"https://downloads.hindawi.com/journals/sp/2020/8899957.pdf","source":{"id":"https://openalex.org/S166774750","display_name":"Scientific Programming","issn_l":"1058-9244","issn":["1058-9244","1875-919X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869"],"host_organization_lineage_names":["Hindawi Publishing Corporation"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Programming","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://downloads.hindawi.com/journals/sp/2020/8899957.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100612177","display_name":"Haitao Yang","orcid":"https://orcid.org/0000-0001-8359-3988"},"institutions":[{"id":"https://openalex.org/I4210100868","display_name":"Second Affiliated Hospital of Dalian Medical University","ror":"https://ror.org/012f2cn18","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210100868"]},{"id":"https://openalex.org/I191996457","display_name":"Dalian Medical University","ror":"https://ror.org/04c8eg608","country_code":"CN","type":"education","lineage":["https://openalex.org/I191996457"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haitao Yang","raw_affiliation_strings":["Department of Anesthesiology, The Second Hospital of Dalian Medical University, Dalian 116027, China"],"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, The Second Hospital of Dalian Medical University, Dalian 116027, China","institution_ids":["https://openalex.org/I191996457","https://openalex.org/I4210100868"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100325282","display_name":"Guan Wang","orcid":"https://orcid.org/0000-0002-5762-8726"},"institutions":[{"id":"https://openalex.org/I191996457","display_name":"Dalian Medical University","ror":"https://ror.org/04c8eg608","country_code":"CN","type":"education","lineage":["https://openalex.org/I191996457"]},{"id":"https://openalex.org/I4210100868","display_name":"Second Affiliated Hospital of Dalian Medical University","ror":"https://ror.org/012f2cn18","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210100868"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guan Wang","raw_affiliation_strings":["Department of Anesthesiology, The Second Hospital of Dalian Medical University, Dalian 116027, China"],"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, The Second Hospital of Dalian Medical University, Dalian 116027, China","institution_ids":["https://openalex.org/I191996457","https://openalex.org/I4210100868"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063351236","display_name":"Jinxia Gao","orcid":"https://orcid.org/0000-0002-4794-3255"},"institutions":[{"id":"https://openalex.org/I191996457","display_name":"Dalian Medical University","ror":"https://ror.org/04c8eg608","country_code":"CN","type":"education","lineage":["https://openalex.org/I191996457"]},{"id":"https://openalex.org/I4210100868","display_name":"Second Affiliated Hospital of Dalian Medical University","ror":"https://ror.org/012f2cn18","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210100868"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jinxia Gao","raw_affiliation_strings":["Department of Anesthesiology, The Second Hospital of Dalian Medical University, Dalian 116027, China"],"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, The Second Hospital of Dalian Medical University, Dalian 116027, China","institution_ids":["https://openalex.org/I191996457","https://openalex.org/I4210100868"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100454002","display_name":"Jie Liu","orcid":"https://orcid.org/0000-0001-5988-8102"},"institutions":[{"id":"https://openalex.org/I4210100868","display_name":"Second Affiliated Hospital of Dalian Medical University","ror":"https://ror.org/012f2cn18","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210100868"]},{"id":"https://openalex.org/I191996457","display_name":"Dalian Medical University","ror":"https://ror.org/04c8eg608","country_code":"CN","type":"education","lineage":["https://openalex.org/I191996457"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jie Liu","raw_affiliation_strings":["Department of Anesthesiology, The Second Hospital of Dalian Medical University, Dalian 116027, China"],"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, The Second Hospital of Dalian Medical University, Dalian 116027, China","institution_ids":["https://openalex.org/I191996457","https://openalex.org/I4210100868"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5063351236","https://openalex.org/A5100454002"],"corresponding_institution_ids":["https://openalex.org/I191996457","https://openalex.org/I4210100868"],"apc_list":{"value":1800,"currency":"USD","value_usd":1800},"apc_paid":{"value":1800,"currency":"USD","value_usd":1800},"fwci":0.5004,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.68961947,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":96},"biblio":{"volume":"2020","issue":null,"first_page":"1","last_page":"11"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10436","display_name":"Anesthesia and Sedative Agents","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10436","display_name":"Anesthesia and Sedative Agents","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.9904000163078308,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11472","display_name":"Analytical Chemistry and Sensors","score":0.9706000089645386,"subfield":{"id":"https://openalex.org/subfields/1502","display_name":"Bioengineering"},"field":{"id":"https://openalex.org/fields/15","display_name":"Chemical Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/unconsciousness","display_name":"Unconsciousness","score":0.9808709621429443},{"id":"https://openalex.org/keywords/sevoflurane","display_name":"Sevoflurane","score":0.9157918095588684},{"id":"https://openalex.org/keywords/bispectral-index","display_name":"Bispectral index","score":0.9077300429344177},{"id":"https://openalex.org/keywords/propofol","display_name":"Propofol","score":0.9003932476043701},{"id":"https://openalex.org/keywords/anesthesia","display_name":"Anesthesia","score":0.8759574890136719},{"id":"https://openalex.org/keywords/anesthetic","display_name":"Anesthetic","score":0.8270058631896973},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.6867654919624329},{"id":"https://openalex.org/keywords/sedation","display_name":"Sedation","score":0.6366994976997375},{"id":"https://openalex.org/keywords/intraoperative-awareness","display_name":"Intraoperative Awareness","score":0.4736253619194031}],"concepts":[{"id":"https://openalex.org/C2776470351","wikidata":"https://www.wikidata.org/wiki/Q12829165","display_name":"Unconsciousness","level":2,"score":0.9808709621429443},{"id":"https://openalex.org/C2781453256","wikidata":"https://www.wikidata.org/wiki/Q419394","display_name":"Sevoflurane","level":2,"score":0.9157918095588684},{"id":"https://openalex.org/C2781097354","wikidata":"https://www.wikidata.org/wiki/Q4918396","display_name":"Bispectral index","level":3,"score":0.9077300429344177},{"id":"https://openalex.org/C2776277131","wikidata":"https://www.wikidata.org/wiki/Q422740","display_name":"Propofol","level":2,"score":0.9003932476043701},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.8759574890136719},{"id":"https://openalex.org/C2778162923","wikidata":"https://www.wikidata.org/wiki/Q4990531","display_name":"Anesthetic","level":2,"score":0.8270058631896973},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6867654919624329},{"id":"https://openalex.org/C2776814716","wikidata":"https://www.wikidata.org/wiki/Q574801","display_name":"Sedation","level":2,"score":0.6366994976997375},{"id":"https://openalex.org/C2910377794","wikidata":"https://www.wikidata.org/wiki/Q1671572","display_name":"Intraoperative Awareness","level":3,"score":0.4736253619194031}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1155/2020/8899957","is_oa":true,"landing_page_url":"http://doi.org/10.1155/2020/8899957","pdf_url":"https://downloads.hindawi.com/journals/sp/2020/8899957.pdf","source":{"id":"https://openalex.org/S166774750","display_name":"Scientific Programming","issn_l":"1058-9244","issn":["1058-9244","1875-919X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869"],"host_organization_lineage_names":["Hindawi Publishing Corporation"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Programming","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:8b04263dca6946e9bfe3665d8cf254dc","is_oa":true,"landing_page_url":"https://doaj.org/article/8b04263dca6946e9bfe3665d8cf254dc","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scientific Programming, Vol 2020 (2020)","raw_type":"article"},{"id":"pmh:oai:hindawi.com:10.1155/2020/8899957","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2020/8899957","pdf_url":null,"source":{"id":"https://openalex.org/S4306400340","display_name":"Hindawi Journal of Chemistry (Hindawi)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210126990","host_organization_name":"Hindawi (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210126990"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Research Article"}],"best_oa_location":{"id":"doi:10.1155/2020/8899957","is_oa":true,"landing_page_url":"http://doi.org/10.1155/2020/8899957","pdf_url":"https://downloads.hindawi.com/journals/sp/2020/8899957.pdf","source":{"id":"https://openalex.org/S166774750","display_name":"Scientific Programming","issn_l":"1058-9244","issn":["1058-9244","1875-919X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869"],"host_organization_lineage_names":["Hindawi Publishing Corporation"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Programming","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5}],"awards":[{"id":"https://openalex.org/G2087396116","display_name":null,"funder_award_id":"China","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3317480652","display_name":null,"funder_award_id":"Science","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4935309172","display_name":null,"funder_award_id":"81471373","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5994120800","display_name":null,"funder_award_id":"Natural","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8643007806","display_name":null,"funder_award_id":"H81471373","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3117223433.pdf","grobid_xml":"https://content.openalex.org/works/W3117223433.grobid-xml"},"referenced_works_count":33,"referenced_works":["https://openalex.org/W269166332","https://openalex.org/W1104581532","https://openalex.org/W1789462828","https://openalex.org/W1867118152","https://openalex.org/W1965002950","https://openalex.org/W2003262300","https://openalex.org/W2012306337","https://openalex.org/W2055748835","https://openalex.org/W2074868599","https://openalex.org/W2104349481","https://openalex.org/W2122459107","https://openalex.org/W2161004273","https://openalex.org/W2208983503","https://openalex.org/W2243582446","https://openalex.org/W2337207680","https://openalex.org/W2405080974","https://openalex.org/W2585476151","https://openalex.org/W2590001269","https://openalex.org/W2605772077","https://openalex.org/W2755789500","https://openalex.org/W2765541077","https://openalex.org/W2772927685","https://openalex.org/W2789360000","https://openalex.org/W2799843901","https://openalex.org/W2803666327","https://openalex.org/W2808035540","https://openalex.org/W2884639583","https://openalex.org/W2904889591","https://openalex.org/W2959467222","https://openalex.org/W2965927198","https://openalex.org/W2976849140","https://openalex.org/W2980411972","https://openalex.org/W3080279411"],"related_works":["https://openalex.org/W1997905937","https://openalex.org/W4230264832","https://openalex.org/W1972830787","https://openalex.org/W2404358141","https://openalex.org/W2008790871","https://openalex.org/W2029696555","https://openalex.org/W2411068776","https://openalex.org/W2382969469","https://openalex.org/W2156423497","https://openalex.org/W3031258101"],"abstract_inverted_index":{"Background.":[0],"There":[1,122],"is":[2,24,163,224],"an":[3,213],"increasing":[4,118],"concern":[5],"of":[6,30,34,51,120,137,141,191,204,235],"awareness":[7],"and":[8,17,32,36,54,68,72,81,131,134,143,145,194,221,223,237],"recall":[9],"during":[10,127],"general":[11],"anesthesia":[12,35,80,103,114,205],"for":[13],"both":[14,158],"the":[15,18,28,56,66,100,111,168,172,176,182,228],"patient":[16,169],"anesthetist.":[19],"The":[20,232],"bispectral":[21],"index":[22,177],"(BIS)":[23],"used":[25],"to":[26,60,64],"assess":[27],"level":[29],"sedation":[31],"depth":[33,203,215],"detect":[37,55],"consciousness":[38,59],"in":[39,74,77],"different":[40],"anesthetic":[41,52,183,214,229],"drugs.":[42],"Middle-latency":[43],"auditory":[44],"evoked":[45],"potentials":[46],"(AEPs)":[47],"also":[48],"quantify":[49],"action":[50],"drugs":[53],"transition":[57],"from":[58],"unconsciousness.":[61],"We":[62,153],"aim":[63],"compare":[65],"sensitivity":[67,220],"specificity":[69,222],"between":[70],"BIS":[71,144,198,236],"AEP":[73,146,195,238],"predicting":[75],"unconsciousness":[76],"inhalational":[78],"sevoflurane":[79,97,112],"intravenous":[82],"propofol":[83,95,101],"anesthesia.":[84,132],"Methods.":[85],"Totally,":[86],"40":[87],"patients":[88],"were":[89,123,147],"randomly":[90],"allocated":[91],"into":[92],"two":[93],"groups:":[94],"or":[96],"group.":[98],"In":[99,110],"group,":[102,113],"was":[104,115,179],"induced":[105,116],"with":[106,157,189,202],"target-controlled":[107],"infusion":[108],"propofol.":[109],"by":[117,181,227],"concentrations":[119,136],"sevoflurane.":[121,197],"3":[124],"end":[125,173],"points":[126],"induction:":[128],"sedation,":[129],"unconsciousness,":[130],"Target":[133],"effect-site":[135],"propofol,":[138],"end-tidal":[139],"concentration":[140],"sevoflurane,":[142],"recorded":[148],"at":[149,160],"each":[150],"stage.":[151],"Results.":[152],"obtained":[154],"good":[155,243],"EC50":[156],"monitors,":[159],"which":[161],"there":[162],"a":[164],"50%":[165],"chance":[166],"that":[167,217],"has":[170],"reached":[171],"point,":[174],"but":[175,208],"variation":[178],"affected":[180,226],"technique.":[184,230],"Propofol":[185],"had":[186,199,218],"higher":[187,200],"correlations":[188,201],"stage":[190],"anesthesia,":[192],"BIS,":[193],"than":[196,206],"AEP,":[207],"we":[209],"did":[210],"not":[211,225,240],"find":[212],"monitor":[216],"high":[219],"Conclusions.":[231],"prediction":[233],"powers":[234],"do":[239],"seem":[241],"as":[242,244],"some":[245],"papers":[246],"mentioned.":[247]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2}],"updated_date":"2026-03-18T14:38:29.013473","created_date":"2025-10-10T00:00:00"}