{"id":"https://openalex.org/W2802611745","doi":"https://doi.org/10.1155/2018/2512037","title":"Computer-Aided Grading of Gliomas Combining Automatic Segmentation and Radiomics","display_name":"Computer-Aided Grading of Gliomas Combining Automatic Segmentation and Radiomics","publication_year":2018,"publication_date":"2018-01-01","ids":{"openalex":"https://openalex.org/W2802611745","doi":"https://doi.org/10.1155/2018/2512037","mag":"2802611745","pmid":"https://pubmed.ncbi.nlm.nih.gov/29853828"},"language":"en","primary_location":{"id":"doi:10.1155/2018/2512037","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2018/2512037","pdf_url":"http://downloads.hindawi.com/journals/ijbi/2018/2512037.pdf","source":{"id":"https://openalex.org/S108408918","display_name":"International Journal of Biomedical Imaging","issn_l":"1687-4188","issn":["1687-4188","1687-4196"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869"],"host_organization_lineage_names":["Hindawi Publishing Corporation"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Biomedical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://downloads.hindawi.com/journals/ijbi/2018/2512037.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100344387","display_name":"Wei Chen","orcid":"https://orcid.org/0000-0002-1281-3389"},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Chen","raw_affiliation_strings":["Department of Biomedical Engineering, School of Control Science and Engineering, Shandong University, Shandong, China"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, School of Control Science and Engineering, Shandong University, Shandong, China","institution_ids":["https://openalex.org/I154099455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061485521","display_name":"Boqiang Liu","orcid":"https://orcid.org/0000-0002-0032-4262"},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Boqiang Liu","raw_affiliation_strings":["Department of Biomedical Engineering, School of Control Science and Engineering, Shandong University, Shandong, China"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, School of Control Science and Engineering, Shandong University, Shandong, China","institution_ids":["https://openalex.org/I154099455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056578734","display_name":"Suting Peng","orcid":null},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Suting Peng","raw_affiliation_strings":["Department of Biomedical Engineering, School of Control Science and Engineering, Shandong University, Shandong, China"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, School of Control Science and Engineering, Shandong University, Shandong, China","institution_ids":["https://openalex.org/I154099455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027855761","display_name":"Jiawei Sun","orcid":"https://orcid.org/0000-0003-1474-8573"},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiawei Sun","raw_affiliation_strings":["Department of Biomedical Engineering, School of Control Science and Engineering, Shandong University, Shandong, China"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, School of Control Science and Engineering, Shandong University, Shandong, China","institution_ids":["https://openalex.org/I154099455"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5040144517","display_name":"Qiao Xu","orcid":"https://orcid.org/0000-0001-6854-7270"},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xu Qiao","raw_affiliation_strings":["Department of Biomedical Engineering, School of Control Science and Engineering, Shandong University, Shandong, China"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, School of Control Science and Engineering, Shandong University, Shandong, China","institution_ids":["https://openalex.org/I154099455"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5061485521"],"corresponding_institution_ids":["https://openalex.org/I154099455"],"apc_list":{"value":900,"currency":"USD","value_usd":900},"apc_paid":{"value":900,"currency":"USD","value_usd":900},"fwci":7.1932,"has_fulltext":true,"cited_by_count":86,"citation_normalized_percentile":{"value":0.97714405,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":100},"biblio":{"volume":"2018","issue":null,"first_page":"1","last_page":"11"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12702","display_name":"Brain Tumor Detection and Classification","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14510","display_name":"Medical Imaging and Analysis","score":0.9930999875068665,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/radiomics","display_name":"Radiomics","score":0.7721630930900574},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6986262798309326},{"id":"https://openalex.org/keywords/grading","display_name":"Grading (engineering)","score":0.6424309015274048},{"id":"https://openalex.org/keywords/glioma","display_name":"Glioma","score":0.48575857281684875},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.4624175727367401},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4024978578090668},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.36900460720062256},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.3324558138847351},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2346266508102417},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.06485697627067566},{"id":"https://openalex.org/keywords/cancer-research","display_name":"Cancer research","score":0.06155326962471008}],"concepts":[{"id":"https://openalex.org/C2778559731","wikidata":"https://www.wikidata.org/wiki/Q23808793","display_name":"Radiomics","level":2,"score":0.7721630930900574},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6986262798309326},{"id":"https://openalex.org/C2777286243","wikidata":"https://www.wikidata.org/wiki/Q5591926","display_name":"Grading (engineering)","level":2,"score":0.6424309015274048},{"id":"https://openalex.org/C2778227246","wikidata":"https://www.wikidata.org/wiki/Q1365309","display_name":"Glioma","level":2,"score":0.48575857281684875},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.4624175727367401},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4024978578090668},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.36900460720062256},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.3324558138847351},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2346266508102417},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.06485697627067566},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.06155326962471008},{"id":"https://openalex.org/C147176958","wikidata":"https://www.wikidata.org/wiki/Q77590","display_name":"Civil engineering","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1155/2018/2512037","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2018/2512037","pdf_url":"http://downloads.hindawi.com/journals/ijbi/2018/2512037.pdf","source":{"id":"https://openalex.org/S108408918","display_name":"International Journal of Biomedical Imaging","issn_l":"1687-4188","issn":["1687-4188","1687-4196"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869"],"host_organization_lineage_names":["Hindawi Publishing Corporation"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Biomedical Imaging","raw_type":"journal-article"},{"id":"pmid:29853828","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29853828","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of biomedical imaging","raw_type":null},{"id":"pmh:oai:doaj.org/article:18997e81dbcb4f3bbc4439a037a86d50","is_oa":true,"landing_page_url":"https://doaj.org/article/18997e81dbcb4f3bbc4439a037a86d50","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Biomedical Imaging, Vol 2018 (2018)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:5964423","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5964423","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Int J Biomed Imaging","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1155/2018/2512037","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2018/2512037","pdf_url":"http://downloads.hindawi.com/journals/ijbi/2018/2512037.pdf","source":{"id":"https://openalex.org/S108408918","display_name":"International Journal of Biomedical Imaging","issn_l":"1687-4188","issn":["1687-4188","1687-4196"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869"],"host_organization_lineage_names":["Hindawi Publishing Corporation"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Biomedical Imaging","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G202754200","display_name":null,"funder_award_id":"2015ZDXX0801A01","funder_id":"https://openalex.org/F4320313895","funder_display_name":"Department of Science and Technology of Shandong Province"},{"id":"https://openalex.org/G2087396116","display_name":null,"funder_award_id":"China","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3317480652","display_name":null,"funder_award_id":"Science","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G37568934","display_name":null,"funder_award_id":"Grant","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G391238517","display_name":null,"funder_award_id":", and","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5285362318","display_name":null,"funder_award_id":"2015ZDXX0801A01","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5939423041","display_name":null,"funder_award_id":"Technology","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5994120800","display_name":null,"funder_award_id":"Natural","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6095175857","display_name":null,"funder_award_id":"2017CXGC1502","funder_id":"https://openalex.org/F4320313895","funder_display_name":"Department of Science and Technology of Shandong Province"},{"id":"https://openalex.org/G7033253288","display_name":null,"funder_award_id":"Grants","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7599363989","display_name":null,"funder_award_id":"ZR2014HQ054","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7780512592","display_name":null,"funder_award_id":"2017CXGC1502","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G804067133","display_name":null,"funder_award_id":"61603218","funder_id":"https://openalex.org/F4320313895","funder_display_name":"Department of Science and Technology of Shandong Province"},{"id":"https://openalex.org/G8848544298","display_name":null,"funder_award_id":"61603218","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G977853076","display_name":null,"funder_award_id":"ZR2014HQ054","funder_id":"https://openalex.org/F4320313895","funder_display_name":"Department of Science and Technology of Shandong Province"}],"funders":[{"id":"https://openalex.org/F4320313895","display_name":"Department of Science and Technology of Shandong Province","ror":"https://ror.org/01b9fvd84"},{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2802611745.pdf","grobid_xml":"https://content.openalex.org/works/W2802611745.grobid-xml"},"referenced_works_count":25,"referenced_works":["https://openalex.org/W1596717185","https://openalex.org/W1641498739","https://openalex.org/W1909740415","https://openalex.org/W1967551258","https://openalex.org/W2028911404","https://openalex.org/W2031071736","https://openalex.org/W2056132907","https://openalex.org/W2103004421","https://openalex.org/W2103987247","https://openalex.org/W2116531017","https://openalex.org/W2117340355","https://openalex.org/W2119440128","https://openalex.org/W2128739912","https://openalex.org/W2141059777","https://openalex.org/W2143426320","https://openalex.org/W2150374672","https://openalex.org/W2154158661","https://openalex.org/W2301358467","https://openalex.org/W2324013702","https://openalex.org/W2366536035","https://openalex.org/W2543050677","https://openalex.org/W2570618306","https://openalex.org/W2751538714","https://openalex.org/W2755044641","https://openalex.org/W2767128594"],"related_works":["https://openalex.org/W3000891326","https://openalex.org/W4205100762","https://openalex.org/W2559998622","https://openalex.org/W2605851261","https://openalex.org/W2734724112","https://openalex.org/W2582997534","https://openalex.org/W3009210156","https://openalex.org/W4388577230","https://openalex.org/W4385221818","https://openalex.org/W3030796519"],"abstract_inverted_index":{"Gliomas":[0],"are":[1,50],"the":[2,9,36,114,125,154,169],"most":[3],"common":[4],"primary":[5],"brain":[6],"tumors,":[7],"and":[8,31,46,80,144,167],"objective":[10],"grading":[11,115,126,164],"is":[12,62,83,111,121],"of":[13,25,72,116,127,132,137,142,149,165],"great":[14],"importance":[15],"for":[16,94,113,124,161,171],"treatment.":[17],"This":[18,151],"paper":[19],"presents":[20],"an":[21,102,130],"automatic":[22,29],"computer-aided":[23],"diagnosis":[24],"gliomas":[26,45,49,128,166],"that":[27,100,153],"combines":[28],"segmentation":[30],"radiomics,":[32],"which":[33],"can":[34,158],"improve":[35],"diagnostic":[37],"ability.":[38],"The":[39],"MRI":[40],"data":[41],"containing":[42],"220":[43],"high-grade":[44],"54":[47],"low-grade":[48],"used":[51],"to":[52,64],"evaluate":[53],"our":[54],"system.":[55],"A":[56,69],"multiscale":[57],"3D":[58],"convolutional":[59],"neural":[60],"network":[61],"trained":[63],"segment":[65],"whole":[66],"tumor":[67],"regions.":[68],"wide":[70],"range":[71],"radiomic":[73],"features":[74,82],"including":[75],"first-order":[76],"features,":[77,79],"shape":[78],"texture":[81],"extracted.":[84],"By":[85],"using":[86],"support":[87],"vector":[88],"machines":[89],"with":[90,107,129],"recursive":[91],"feature":[92,95],"elimination":[93],"selection,":[96],"a":[97,108,134,139,145],"CAD":[98,119,156],"system":[99,120,157],"has":[101,168],"extreme":[103],"gradient":[104],"boosting":[105],"classifier":[106],"5-fold":[109],"cross-validation":[110],"constructed":[112],"gliomas.":[117],"Our":[118],"highly":[122],"effective":[123],"accuracy":[131],"91.27%,":[133,138,143],"weighted":[135,140,146],"macroprecision":[136],"macrorecall":[141],"macro-<i>F</i>1":[147],"score":[148],"90.64%.":[150],"demonstrates":[152],"proposed":[155],"assist":[159],"radiologists":[160],"high":[162],"accurate":[163],"potential":[170],"clinical":[172],"applications.":[173]},"counts_by_year":[{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":20},{"year":2021,"cited_by_count":20},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":11},{"year":2018,"cited_by_count":1}],"updated_date":"2026-04-18T07:56:08.524223","created_date":"2025-10-10T00:00:00"}
