{"id":"https://openalex.org/W2341782166","doi":"https://doi.org/10.1155/2016/5670851","title":"Feature Selection Has a Large Impact on One-Class Classification Accuracy for MicroRNAs in Plants","display_name":"Feature Selection Has a Large Impact on One-Class Classification Accuracy for MicroRNAs in Plants","publication_year":2016,"publication_date":"2016-04-12","ids":{"openalex":"https://openalex.org/W2341782166","doi":"https://doi.org/10.1155/2016/5670851","mag":"2341782166","pmid":"https://pubmed.ncbi.nlm.nih.gov/27190509"},"language":"en","primary_location":{"id":"doi:10.1155/2016/5670851","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2016/5670851","pdf_url":"http://downloads.hindawi.com/journals/abi/2016/5670851.pdf","source":{"id":"https://openalex.org/S146125958","display_name":"Advances in Bioinformatics","issn_l":"1687-8027","issn":["1687-8027","1687-8035"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869"],"host_organization_lineage_names":["Hindawi Publishing Corporation"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"http://downloads.hindawi.com/journals/abi/2016/5670851.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091900270","display_name":"Malik Yousef","orcid":"https://orcid.org/0000-0001-8780-6303"},"institutions":[{"id":"https://openalex.org/I4210098726","display_name":"Sakhnin College","ror":"https://ror.org/013fwa311","country_code":"IL","type":"education","lineage":["https://openalex.org/I4210098726"]}],"countries":["IL"],"is_corresponding":true,"raw_author_name":"Malik Yousef","raw_affiliation_strings":["Computer Science, The College of Sakhnin, 30810 Sakhnin, Israel","The Institute of Applied Research, The Galilee Society, P.O. Box 437, 20200 Shefa Amr, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computer Science, The College of Sakhnin, 30810 Sakhnin, Israel","institution_ids":["https://openalex.org/I4210098726"]},{"raw_affiliation_string":"The Institute of Applied Research, The Galilee Society, P.O. Box 437, 20200 Shefa Amr, Israel","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065447125","display_name":"M\u00fc\u015ferref Duygu Sa\u00e7ar Demirci","orcid":"https://orcid.org/0000-0003-2012-0598"},"institutions":[{"id":"https://openalex.org/I120217413","display_name":"Izmir Institute of Technology","ror":"https://ror.org/03stptj97","country_code":"TR","type":"education","lineage":["https://openalex.org/I120217413"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"M\u00fc\u015ferref Duygu Sa\u00e7ar Demirci","raw_affiliation_strings":["Molecular Biology and Genetics, Izmir Institute of Technology, Urla, 35430 Izmir, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular Biology and Genetics, Izmir Institute of Technology, Urla, 35430 Izmir, Turkey","institution_ids":["https://openalex.org/I120217413"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067023018","display_name":"Waleed Khalifa","orcid":null},"institutions":[{"id":"https://openalex.org/I4210098726","display_name":"Sakhnin College","ror":"https://ror.org/013fwa311","country_code":"IL","type":"education","lineage":["https://openalex.org/I4210098726"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Waleed Khalifa","raw_affiliation_strings":["Computer Science, The College of Sakhnin, 30810 Sakhnin, Israel","The Institute of Applied Research, The Galilee Society, P.O. Box 437, 20200 Shefa Amr, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computer Science, The College of Sakhnin, 30810 Sakhnin, Israel","institution_ids":["https://openalex.org/I4210098726"]},{"raw_affiliation_string":"The Institute of Applied Research, The Galilee Society, P.O. Box 437, 20200 Shefa Amr, Israel","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043036637","display_name":"Jens Allmer","orcid":"https://orcid.org/0000-0002-2164-7335"},"institutions":[{"id":"https://openalex.org/I120217413","display_name":"Izmir Institute of Technology","ror":"https://ror.org/03stptj97","country_code":"TR","type":"education","lineage":["https://openalex.org/I120217413"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Jens Allmer","raw_affiliation_strings":["Bionia Incorporated, IZTEKGEB A8, Urla, 35430 Izmir, Turkey","Molecular Biology and Genetics, Izmir Institute of Technology, Urla, 35430 Izmir, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bionia Incorporated, IZTEKGEB A8, Urla, 35430 Izmir, Turkey","institution_ids":[]},{"raw_affiliation_string":"Molecular Biology and Genetics, Izmir Institute of Technology, Urla, 35430 Izmir, Turkey","institution_ids":["https://openalex.org/I120217413"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5091900270"],"corresponding_institution_ids":["https://openalex.org/I4210098726"],"apc_list":null,"apc_paid":null,"fwci":1.8596,"has_fulltext":true,"cited_by_count":26,"citation_normalized_percentile":{"value":0.83678663,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"2016","issue":null,"first_page":"1","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9966999888420105,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9966999888420105,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10184","display_name":"Plant Molecular Biology Research","score":0.9904000163078308,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/feature-selection","display_name":"Feature selection","score":0.7939743995666504},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.7630139589309692},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7186248302459717},{"id":"https://openalex.org/keywords/classifier","display_name":"Classifier (UML)","score":0.6496838927268982},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.6407978534698486},{"id":"https://openalex.org/keywords/class","display_name":"Class (philosophy)","score":0.5661935210227966},{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.5273562073707581},{"id":"https://openalex.org/keywords/cluster-analysis","display_name":"Cluster analysis","score":0.508499026298523},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.4520946145057678},{"id":"https://openalex.org/keywords/one-class-classification","display_name":"One-class classification","score":0.43751204013824463},{"id":"https://openalex.org/keywords/linear-classifier","display_name":"Linear classifier","score":0.4205315113067627},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.40026187896728516}],"concepts":[{"id":"https://openalex.org/C148483581","wikidata":"https://www.wikidata.org/wiki/Q446488","display_name":"Feature selection","level":2,"score":0.7939743995666504},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.7630139589309692},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7186248302459717},{"id":"https://openalex.org/C95623464","wikidata":"https://www.wikidata.org/wiki/Q1096149","display_name":"Classifier (UML)","level":2,"score":0.6496838927268982},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.6407978534698486},{"id":"https://openalex.org/C2777212361","wikidata":"https://www.wikidata.org/wiki/Q5127848","display_name":"Class (philosophy)","level":2,"score":0.5661935210227966},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.5273562073707581},{"id":"https://openalex.org/C73555534","wikidata":"https://www.wikidata.org/wiki/Q622825","display_name":"Cluster analysis","level":2,"score":0.508499026298523},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.4520946145057678},{"id":"https://openalex.org/C34872919","wikidata":"https://www.wikidata.org/wiki/Q7092302","display_name":"One-class classification","level":3,"score":0.43751204013824463},{"id":"https://openalex.org/C139532973","wikidata":"https://www.wikidata.org/wiki/Q2679259","display_name":"Linear classifier","level":3,"score":0.4205315113067627},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.40026187896728516},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.1155/2016/5670851","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2016/5670851","pdf_url":"http://downloads.hindawi.com/journals/abi/2016/5670851.pdf","source":{"id":"https://openalex.org/S146125958","display_name":"Advances in Bioinformatics","issn_l":"1687-8027","issn":["1687-8027","1687-8035"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869"],"host_organization_lineage_names":["Hindawi Publishing Corporation"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Bioinformatics","raw_type":"journal-article"},{"id":"pmid:27190509","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27190509","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:178eb8c102064ef6bfebac2952d7fa1b","is_oa":false,"landing_page_url":"https://doaj.org/article/178eb8c102064ef6bfebac2952d7fa1b","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Advances in Bioinformatics, Vol 2016 (2016)","raw_type":"article"},{"id":"pmh:oai:openaccess.iyte.edu.tr:11147/5791","is_oa":true,"landing_page_url":"http://hdl.handle.net/11147/5791","pdf_url":null,"source":{"id":"https://openalex.org/S4377196445","display_name":"IYTE GCRIS Database (Izmir Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I120217413","host_organization_name":"Izmir Institute of Technology","host_organization_lineage":["https://openalex.org/I120217413"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:openaccess.iyte.edu.tr:8080:11147/5791","is_oa":true,"landing_page_url":"http://doi.org/10.1155/2016/5670851","pdf_url":null,"source":{"id":"https://openalex.org/S4306400894","display_name":"\u0130YTE (\u0130ZM\u0130R Y\u00dcKSEK TEKNOLOJ\u0130 ENST\u0130T\u00dcS\u00dc)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I120217413","host_organization_name":"Izmir Institute of Technology","host_organization_lineage":["https://openalex.org/I120217413"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4844869","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4844869","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Adv Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1155/2016/5670851","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2016/5670851","pdf_url":"http://downloads.hindawi.com/journals/abi/2016/5670851.pdf","source":{"id":"https://openalex.org/S146125958","display_name":"Advances in Bioinformatics","issn_l":"1687-8027","issn":["1687-8027","1687-8035"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869"],"host_organization_lineage_names":["Hindawi Publishing Corporation"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G880084475","display_name":null,"funder_award_id":"113E326","funder_id":"https://openalex.org/F4320322626","funder_display_name":"T\u00fcrkiye Bilimsel ve Teknolojik Ara\u015ft\u0131rma Kurumu"}],"funders":[{"id":"https://openalex.org/F4320322626","display_name":"T\u00fcrkiye Bilimsel ve Teknolojik Ara\u015ft\u0131rma Kurumu","ror":"https://ror.org/04w9kkr77"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2341782166.pdf","grobid_xml":"https://content.openalex.org/works/W2341782166.grobid-xml"},"referenced_works_count":36,"referenced_works":["https://openalex.org/W1253096047","https://openalex.org/W1497879779","https://openalex.org/W1835740130","https://openalex.org/W1954076721","https://openalex.org/W1978379303","https://openalex.org/W1991244466","https://openalex.org/W1993837624","https://openalex.org/W2020350008","https://openalex.org/W2021546954","https://openalex.org/W2046584841","https://openalex.org/W2051535323","https://openalex.org/W2053835153","https://openalex.org/W2056234582","https://openalex.org/W2063555458","https://openalex.org/W2070571588","https://openalex.org/W2075779886","https://openalex.org/W2093213907","https://openalex.org/W2093358254","https://openalex.org/W2100928957","https://openalex.org/W2107961632","https://openalex.org/W2114973325","https://openalex.org/W2120583228","https://openalex.org/W2120794445","https://openalex.org/W2131904035","https://openalex.org/W2133990480","https://openalex.org/W2138154105","https://openalex.org/W2138664009","https://openalex.org/W2140751493","https://openalex.org/W2143426320","https://openalex.org/W2154513100","https://openalex.org/W2184343450","https://openalex.org/W2215710308","https://openalex.org/W2274610632","https://openalex.org/W2345987083","https://openalex.org/W2418959584","https://openalex.org/W2470585343"],"related_works":["https://openalex.org/W3112445271","https://openalex.org/W2368894008","https://openalex.org/W2134510694","https://openalex.org/W2109566635","https://openalex.org/W1964081096","https://openalex.org/W2141335490","https://openalex.org/W3139983161","https://openalex.org/W2169139688","https://openalex.org/W563719335","https://openalex.org/W2021546954"],"abstract_inverted_index":{"MicroRNAs":[0],"(miRNAs)":[1],"are":[2,64],"short":[3],"RNA":[4],"sequences":[5],"involved":[6],"in":[7,37,108,122,166],"posttranscriptional":[8],"gene":[9],"regulation.":[10],"Their":[11],"experimental":[12],"analysis":[13],"is":[14,30,70,117],"complicated":[15],"and,":[16],"therefore,":[17],"needs":[18],"to":[19,47,72,79,91,119,184],"be":[20,48,163],"supplemented":[21],"with":[22,110],"computational":[23,27],"miRNA":[24,28,152],"detection.":[25],"Currently":[26],"detection":[29,153],"mainly":[31],"performed":[32],"using":[33,97],"machine":[34,42,62],"learning":[35,63],"and":[36,50,113,177],"particular":[38],"two-class":[39,85,94],"classification.":[40,86],"For":[41],"learning,":[43],"the":[44,134,167,173],"miRNAs":[45],"need":[46],"parametrized":[49],"more":[51],"than":[52],"700":[53],"features":[54],"have":[55],"been":[56],"described.":[57],"Positive":[58],"training":[59,135,175],"examples":[60,176],"for":[61],"readily":[65],"available,":[66],"but":[67],"negative":[68],"data":[69],"hard":[71],"come":[73],"by.":[74],"Therefore,":[75],"it":[76],"seems":[77],"prerogative":[78],"use":[80],"one-class":[81,98,111,138],"classification":[82,95,112],"instead":[83],"of":[84,136,145,172],"Previously,":[87],"we":[88,103],"were":[89],"able":[90],"almost":[92],"reach":[93],"accuracy":[96,123,144],"classifiers.":[99],"In":[100],"this":[101,161],"work,":[102],"employ":[104],"feature":[105,126,131,181,188],"selection":[106,127],"procedures":[107],"conjunction":[109],"show":[114],"that":[115,160],"there":[116],"up":[118],"36%":[120],"difference":[121],"among":[124],"these":[125],"methods.":[128],"The":[129],"best":[130],"set":[132],"allowed":[133],"a":[137],"classifier":[139],"which":[140],"achieved":[141],"an":[142],"average":[143],"~95.6%":[146],"thereby":[147],"outperforming":[148],"previous":[149],"two-class-based":[150],"plant":[151],"approaches":[154],"by":[155,169,178],"about":[156],"0.5%.":[157],"We":[158],"believe":[159],"can":[162],"improved":[164],"upon":[165],"future":[168],"rigorous":[170],"filtering":[171],"positive":[174],"improving":[179],"current":[180],"clustering":[182],"algorithms":[183],"better":[185],"target":[186],"pre-miRNA":[187],"selection.":[189]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":6}],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2025-10-10T00:00:00"}