{"id":"https://openalex.org/W1856831978","doi":"https://doi.org/10.1155/2015/972851","title":"Analyzing the Correlation between the Level of Serum Markers and Ischemic Cerebral Vascular Disease by Multiple Parameters","display_name":"Analyzing the Correlation between the Level of Serum Markers and Ischemic Cerebral Vascular Disease by Multiple Parameters","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W1856831978","doi":"https://doi.org/10.1155/2015/972851","mag":"1856831978","pmid":"https://pubmed.ncbi.nlm.nih.gov/26609318"},"language":"en","primary_location":{"id":"doi:10.1155/2015/972851","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2015/972851","pdf_url":"https://downloads.hindawi.com/journals/cmmm/2015/972851.pdf","source":{"id":"https://openalex.org/S36980176","display_name":"Computational and Mathematical Methods in Medicine","issn_l":"1748-670X","issn":["1748-670X","1748-6718"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869"],"host_organization_lineage_names":["Hindawi Publishing Corporation"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computational and Mathematical Methods in Medicine","raw_type":"journal-article"},"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://downloads.hindawi.com/journals/cmmm/2015/972851.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050548760","display_name":"Lai-Bin Dong","orcid":null},"institutions":[{"id":"https://openalex.org/I4210149496","display_name":"Zhengzhou People's Hospital","ror":"https://ror.org/04tgrpw60","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210149496"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Laibin Dong","raw_affiliation_strings":["Department of Neurology, The Ninth People\u2019s Hospital of Zhengzhou, Zhengzhou 450000, China","Department of Neurology, The Ninth People's Hospital of Zhengzhou, Zhengzhou 450000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, The Ninth People\u2019s Hospital of Zhengzhou, Zhengzhou 450000, China","institution_ids":["https://openalex.org/I4210149496"]},{"raw_affiliation_string":"Department of Neurology, The Ninth People's Hospital of Zhengzhou, Zhengzhou 450000, China","institution_ids":["https://openalex.org/I4210149496"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Rongzhi Hou","orcid":null},"institutions":[{"id":"https://openalex.org/I4210149496","display_name":"Zhengzhou People's Hospital","ror":"https://ror.org/04tgrpw60","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210149496"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Rongzhi Hou","raw_affiliation_strings":["Department of Neurology, The Ninth People\u2019s Hospital of Zhengzhou, Zhengzhou 450000, China","Department of Neurology, The Ninth People's Hospital of Zhengzhou, Zhengzhou 450000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, The Ninth People\u2019s Hospital of Zhengzhou, Zhengzhou 450000, China","institution_ids":["https://openalex.org/I4210149496"]},{"raw_affiliation_string":"Department of Neurology, The Ninth People's Hospital of Zhengzhou, Zhengzhou 450000, China","institution_ids":["https://openalex.org/I4210149496"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110838202","display_name":"Yuxia Xu","orcid":null},"institutions":[{"id":"https://openalex.org/I4210149496","display_name":"Zhengzhou People's Hospital","ror":"https://ror.org/04tgrpw60","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210149496"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuxia Xu","raw_affiliation_strings":["Department of Neurology, The Ninth People\u2019s Hospital of Zhengzhou, Zhengzhou 450000, China","Department of Neurology, The Ninth People's Hospital of Zhengzhou, Zhengzhou 450000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, The Ninth People\u2019s Hospital of Zhengzhou, Zhengzhou 450000, China","institution_ids":["https://openalex.org/I4210149496"]},{"raw_affiliation_string":"Department of Neurology, The Ninth People's Hospital of Zhengzhou, Zhengzhou 450000, China","institution_ids":["https://openalex.org/I4210149496"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104196901","display_name":"Jiaying Yuan","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jiaying Yuan","raw_affiliation_strings":["Department of Ultrasound Diagnosis, Hospital of Henan Military Region, Zhengzhou 450000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ultrasound Diagnosis, Hospital of Henan Military Region, Zhengzhou 450000, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100376799","display_name":"Lijun Li","orcid":"https://orcid.org/0000-0003-3651-3441"},"institutions":[{"id":"https://openalex.org/I4210149496","display_name":"Zhengzhou People's Hospital","ror":"https://ror.org/04tgrpw60","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210149496"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lijun Li","raw_affiliation_strings":["Department of Neurology, The Ninth People\u2019s Hospital of Zhengzhou, Zhengzhou 450000, China","Department of Neurology, The Ninth People's Hospital of Zhengzhou, Zhengzhou 450000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, The Ninth People\u2019s Hospital of Zhengzhou, Zhengzhou 450000, China","institution_ids":["https://openalex.org/I4210149496"]},{"raw_affiliation_string":"Department of Neurology, The Ninth People's Hospital of Zhengzhou, Zhengzhou 450000, China","institution_ids":["https://openalex.org/I4210149496"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076102700","display_name":"Chao Zheng","orcid":"https://orcid.org/0000-0002-5286-6485"},"institutions":[{"id":"https://openalex.org/I4210149496","display_name":"Zhengzhou People's Hospital","ror":"https://ror.org/04tgrpw60","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210149496"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chao Zheng","raw_affiliation_strings":["Department of Neurology, The Ninth People\u2019s Hospital of Zhengzhou, Zhengzhou 450000, China","Department of Neurology, The Ninth People's Hospital of Zhengzhou, Zhengzhou 450000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, The Ninth People\u2019s Hospital of Zhengzhou, Zhengzhou 450000, China","institution_ids":["https://openalex.org/I4210149496"]},{"raw_affiliation_string":"Department of Neurology, The Ninth People's Hospital of Zhengzhou, Zhengzhou 450000, China","institution_ids":["https://openalex.org/I4210149496"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5047158773","display_name":"Hehua Zhao","orcid":"https://orcid.org/0000-0003-0600-3379"},"institutions":[{"id":"https://openalex.org/I4210149496","display_name":"Zhengzhou People's Hospital","ror":"https://ror.org/04tgrpw60","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210149496"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hehua Zhao","raw_affiliation_strings":["Department of Neurology, The Ninth People\u2019s Hospital of Zhengzhou, Zhengzhou 450000, China","Department of Neurology, The Ninth People's Hospital of Zhengzhou, Zhengzhou 450000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, The Ninth People\u2019s Hospital of Zhengzhou, Zhengzhou 450000, China","institution_ids":["https://openalex.org/I4210149496"]},{"raw_affiliation_string":"Department of Neurology, The Ninth People's Hospital of Zhengzhou, Zhengzhou 450000, China","institution_ids":["https://openalex.org/I4210149496"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5050548760"],"corresponding_institution_ids":["https://openalex.org/I4210149496"],"apc_list":{"value":2100,"currency":"USD","value_usd":2100},"apc_paid":{"value":2100,"currency":"USD","value_usd":2100},"fwci":0.928,"has_fulltext":true,"cited_by_count":12,"citation_normalized_percentile":{"value":0.76922574,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"2015","issue":null,"first_page":"1","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14144","display_name":"Neurological Disease Mechanisms and Treatments","score":0.2847999930381775,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T14144","display_name":"Neurological Disease Mechanisms and Treatments","score":0.2847999930381775,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12030","display_name":"S100 Proteins and Annexins","score":0.09359999746084213,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":0.09080000221729279,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/logistic-regression","display_name":"Logistic regression","score":0.7712485790252686},{"id":"https://openalex.org/keywords/receiver-operating-characteristic","display_name":"Receiver operating characteristic","score":0.7460085153579712},{"id":"https://openalex.org/keywords/univariate","display_name":"Univariate","score":0.633278489112854},{"id":"https://openalex.org/keywords/correlation","display_name":"Correlation","score":0.6116898655891418},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.6103534698486328},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.6095870137214661},{"id":"https://openalex.org/keywords/univariate-analysis","display_name":"Univariate analysis","score":0.5322055220603943},{"id":"https://openalex.org/keywords/gastroenterology","display_name":"Gastroenterology","score":0.5212231874465942},{"id":"https://openalex.org/keywords/multivariate-statistics","display_name":"Multivariate statistics","score":0.5026359558105469},{"id":"https://openalex.org/keywords/area-under-the-curve","display_name":"Area under the curve","score":0.4922696650028229},{"id":"https://openalex.org/keywords/multivariate-analysis","display_name":"Multivariate analysis","score":0.46890437602996826},{"id":"https://openalex.org/keywords/cardiology","display_name":"Cardiology","score":0.3531181812286377},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.09259214997291565},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.07795652747154236}],"concepts":[{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.7712485790252686},{"id":"https://openalex.org/C58471807","wikidata":"https://www.wikidata.org/wiki/Q327120","display_name":"Receiver operating characteristic","level":2,"score":0.7460085153579712},{"id":"https://openalex.org/C199163554","wikidata":"https://www.wikidata.org/wiki/Q1681619","display_name":"Univariate","level":3,"score":0.633278489112854},{"id":"https://openalex.org/C117220453","wikidata":"https://www.wikidata.org/wiki/Q5172842","display_name":"Correlation","level":2,"score":0.6116898655891418},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6103534698486328},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6095870137214661},{"id":"https://openalex.org/C144301174","wikidata":"https://www.wikidata.org/wiki/Q7893852","display_name":"Univariate analysis","level":3,"score":0.5322055220603943},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.5212231874465942},{"id":"https://openalex.org/C161584116","wikidata":"https://www.wikidata.org/wiki/Q1952580","display_name":"Multivariate statistics","level":2,"score":0.5026359558105469},{"id":"https://openalex.org/C76318530","wikidata":"https://www.wikidata.org/wiki/Q16833590","display_name":"Area under the curve","level":2,"score":0.4922696650028229},{"id":"https://openalex.org/C38180746","wikidata":"https://www.wikidata.org/wiki/Q1952580","display_name":"Multivariate analysis","level":2,"score":0.46890437602996826},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.3531181812286377},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.09259214997291565},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.07795652747154236},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D002097","descriptor_name":"C-Reactive Protein","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002097","descriptor_name":"C-Reactive Protein","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002097","descriptor_name":"C-Reactive Protein","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D006710","descriptor_name":"Homocysteine","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D006710","descriptor_name":"Homocysteine","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D006710","descriptor_name":"Homocysteine","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008075","descriptor_name":"Lipoproteins, HDL","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008075","descriptor_name":"Lipoproteins, HDL","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008075","descriptor_name":"Lipoproteins, HDL","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D009418","descriptor_name":"S100 Proteins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D009418","descriptor_name":"S100 Proteins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D009418","descriptor_name":"S100 Proteins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D010751","descriptor_name":"Phosphopyruvate Hydratase","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D010751","descriptor_name":"Phosphopyruvate Hydratase","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D010751","descriptor_name":"Phosphopyruvate Hydratase","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D015850","descriptor_name":"Interleukin-6","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D015850","descriptor_name":"Interleukin-6","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D015850","descriptor_name":"Interleukin-6","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019540","descriptor_name":"Area Under Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019540","descriptor_name":"Area Under Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019540","descriptor_name":"Area Under Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1155/2015/972851","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2015/972851","pdf_url":"https://downloads.hindawi.com/journals/cmmm/2015/972851.pdf","source":{"id":"https://openalex.org/S36980176","display_name":"Computational and Mathematical Methods in Medicine","issn_l":"1748-670X","issn":["1748-670X","1748-6718"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869"],"host_organization_lineage_names":["Hindawi Publishing Corporation"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computational and Mathematical Methods in Medicine","raw_type":"journal-article"},{"id":"pmid:26609318","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26609318","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computational and mathematical methods in medicine","raw_type":null},{"id":"pmh:oai:europepmc.org:3627539","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4644555","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1155/2015/972851","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2015/972851","pdf_url":"https://downloads.hindawi.com/journals/cmmm/2015/972851.pdf","source":{"id":"https://openalex.org/S36980176","display_name":"Computational and Mathematical Methods in Medicine","issn_l":"1748-670X","issn":["1748-670X","1748-6718"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869"],"host_organization_lineage_names":["Hindawi Publishing Corporation"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computational and Mathematical Methods in Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.7200000286102295,"id":"https://metadata.un.org/sdg/3"}],"awards":[{"id":"https://openalex.org/G3760244468","display_name":null,"funder_award_id":"81303150","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1856831978.pdf","grobid_xml":"https://content.openalex.org/works/W1856831978.grobid-xml"},"referenced_works_count":7,"referenced_works":["https://openalex.org/W1993437978","https://openalex.org/W2023593727","https://openalex.org/W2033276124","https://openalex.org/W2075218724","https://openalex.org/W2122906454","https://openalex.org/W2146775766","https://openalex.org/W2377702143"],"related_works":["https://openalex.org/W1828158523","https://openalex.org/W2049578243","https://openalex.org/W2000145235","https://openalex.org/W2122079181","https://openalex.org/W1985848810","https://openalex.org/W2889939530","https://openalex.org/W3121881699","https://openalex.org/W2748838164","https://openalex.org/W2066015000","https://openalex.org/W2912721996"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"explore":[2],"the":[3,36,40,49,71,82,97,101,111,120,123,130,143,172,192],"serum":[4,61],"markers":[5],"associated":[6],"with":[7,24,158,171,181],"ischemic":[8],"cerebral":[9],"vascular":[10],"disease":[11],"(ICVD)":[12],"and":[13,21,26,29,39,51,69,90,127,129,154,162,188],"discuss":[14],"their":[15,57],"diagnostic":[16,72],"value.":[17,73],"METHODS:":[18],"Two":[19],"hundred":[20,28],"eighty-eight":[22],"patients":[23,81],"ICVD":[25,80,133,195],"one":[27],"eighty":[30],"healthy":[31,98,112],"persons":[32],"were":[33,92],"enrolled":[34],"as":[35],"case":[37],"group":[38],"control":[41],"group,":[42],"respectively.":[43],"This":[44],"paper":[45],"then":[46],"carried":[47],"out":[48],"univariate":[50],"multivariate":[52,115],"logistic":[53],"regression":[54,116],"analyses":[55],"of":[56,60,66,84,96,103,110,125,132,146,152,160,164,174,186,194],"respective":[58],"levels":[59,83],"markers,":[62],"made":[63],"combined":[64],"analysis":[65,117],"related":[67],"factors,":[68],"detected":[70],"RESULTS:":[74],"Meta-analysis":[75],"results":[76],"showed":[77],"that":[78,109,119],"for":[79],"CRP,":[85],"S-100,":[86],"TNF-\u03b1,":[87],"HCY,":[88],"NSE,":[89],"IL-6":[91],"higher":[93],"than":[94,108],"those":[95],"persons,":[99],"while":[100,176],"level":[102,124],"HDL":[104,126,153,167,187],"was":[105,134,156,178],"obviously":[106],"lower":[107],"persons.":[113],"The":[114,140,183],"indicated":[118],"association":[121],"between":[122],"TNF-\u03b1":[128,155,177,189],"occurrence":[131,173],"statistically":[135],"significant":[136],"(P":[137],"<":[138],"0.05).":[139],"area":[141],"under":[142],"curves":[144],"(AUC)":[145],"receiver":[147],"operating":[148],"characteristic":[149],"(ROC)":[150],"curve":[151],"0.916,":[157],"sensitivity":[159],"90.91%":[161],"specificity":[163],"76.47%.":[165],"CONCLUSION:":[166],"has":[168],"negative":[169],"correlation":[170],"ICVD,":[175],"positively":[179],"correlated":[180],"it.":[182],"combination":[184],"test":[185],"could":[190],"raise":[191],"accuracy":[193],"diagnosis.":[196]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2025-10-10T00:00:00"}