{"id":"https://openalex.org/W2061985730","doi":"https://doi.org/10.1155/2015/415923","title":"PET-Specific Parameters and Radiotracers in Theoretical Tumour Modelling","display_name":"PET-Specific Parameters and Radiotracers in Theoretical Tumour Modelling","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W2061985730","doi":"https://doi.org/10.1155/2015/415923","mag":"2061985730","pmid":"https://pubmed.ncbi.nlm.nih.gov/25788973"},"language":"en","primary_location":{"id":"doi:10.1155/2015/415923","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2015/415923","pdf_url":"https://downloads.hindawi.com/journals/cmmm/2015/415923.pdf","source":{"id":"https://openalex.org/S36980176","display_name":"Computational and Mathematical Methods in Medicine","issn_l":"1748-670X","issn":["1748-670X","1748-6718"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869"],"host_organization_lineage_names":["Hindawi Publishing Corporation"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computational and Mathematical Methods in Medicine","raw_type":"journal-article"},"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://downloads.hindawi.com/journals/cmmm/2015/415923.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5057473472","display_name":"Matthew Jennings","orcid":"https://orcid.org/0000-0002-1288-2683"},"institutions":[{"id":"https://openalex.org/I1320133117","display_name":"Royal Adelaide Hospital","ror":"https://ror.org/00carf720","country_code":"AU","type":"funder","lineage":["https://openalex.org/I1320133117","https://openalex.org/I4392738059"]},{"id":"https://openalex.org/I5681781","display_name":"University of Adelaide","ror":"https://ror.org/00892tw58","country_code":"AU","type":"education","lineage":["https://openalex.org/I5681781"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Matthew Jennings","raw_affiliation_strings":["Department of Medical Physics, Royal Adelaide Hospital, Adelaide, SA 5000, Australia","School of Chemistry & Physics, University of Adelaide, Adelaide, SA 5000, Australia"],"affiliations":[{"raw_affiliation_string":"Department of Medical Physics, Royal Adelaide Hospital, Adelaide, SA 5000, Australia","institution_ids":["https://openalex.org/I1320133117"]},{"raw_affiliation_string":"School of Chemistry & Physics, University of Adelaide, Adelaide, SA 5000, Australia","institution_ids":["https://openalex.org/I5681781"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009380500","display_name":"Loredana G. Marcu","orcid":"https://orcid.org/0000-0002-6703-979X"},"institutions":[{"id":"https://openalex.org/I5681781","display_name":"University of Adelaide","ror":"https://ror.org/00892tw58","country_code":"AU","type":"education","lineage":["https://openalex.org/I5681781"]},{"id":"https://openalex.org/I162871001","display_name":"University of Oradea","ror":"https://ror.org/00wzhv093","country_code":"RO","type":"education","lineage":["https://openalex.org/I162871001"]}],"countries":["AU","RO"],"is_corresponding":false,"raw_author_name":"Loredana G. Marcu","raw_affiliation_strings":["Faculty of Science, University of Oradea, 410087 Oradea, Romania","School of Chemistry & Physics, University of Adelaide, Adelaide, SA 5000, Australia"],"affiliations":[{"raw_affiliation_string":"Faculty of Science, University of Oradea, 410087 Oradea, Romania","institution_ids":["https://openalex.org/I162871001"]},{"raw_affiliation_string":"School of Chemistry & Physics, University of Adelaide, Adelaide, SA 5000, Australia","institution_ids":["https://openalex.org/I5681781"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027460327","display_name":"Eva Bezak","orcid":"https://orcid.org/0000-0002-1315-1735"},"institutions":[{"id":"https://openalex.org/I5681781","display_name":"University of Adelaide","ror":"https://ror.org/00892tw58","country_code":"AU","type":"education","lineage":["https://openalex.org/I5681781"]},{"id":"https://openalex.org/I1320133117","display_name":"Royal Adelaide Hospital","ror":"https://ror.org/00carf720","country_code":"AU","type":"funder","lineage":["https://openalex.org/I1320133117","https://openalex.org/I4392738059"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Eva Bezak","raw_affiliation_strings":["Department of Medical Physics, Royal Adelaide Hospital, Adelaide, SA 5000, Australia","School of Chemistry & Physics, University of Adelaide, Adelaide, SA 5000, Australia"],"affiliations":[{"raw_affiliation_string":"Department of Medical Physics, Royal Adelaide Hospital, Adelaide, SA 5000, Australia","institution_ids":["https://openalex.org/I1320133117"]},{"raw_affiliation_string":"School of Chemistry & Physics, University of Adelaide, Adelaide, SA 5000, Australia","institution_ids":["https://openalex.org/I5681781"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5057473472"],"corresponding_institution_ids":["https://openalex.org/I1320133117","https://openalex.org/I5681781"],"apc_list":{"value":2100,"currency":"USD","value_usd":2100},"apc_paid":{"value":2100,"currency":"USD","value_usd":2100},"fwci":0.5857,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.66787624,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"2015","issue":null,"first_page":"1","last_page":"11"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10631","display_name":"Cancer, Hypoxia, and Metabolism","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10631","display_name":"Cancer, Hypoxia, and Metabolism","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11829","display_name":"Mathematical Biology Tumor Growth","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/2611","display_name":"Modeling and Simulation"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.9954000115394592,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/in-silico","display_name":"In silico","score":0.8441020250320435},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5027515888214111},{"id":"https://openalex.org/keywords/positron-emission-tomography","display_name":"Positron emission tomography","score":0.4589269459247589},{"id":"https://openalex.org/keywords/computational-model","display_name":"Computational model","score":0.43108242750167847},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.3874574303627014},{"id":"https://openalex.org/keywords/nuclear-medicine","display_name":"Nuclear medicine","score":0.31096938252449036},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2865878939628601},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.2064756155014038},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.1815587878227234},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.08932077884674072}],"concepts":[{"id":"https://openalex.org/C2775905019","wikidata":"https://www.wikidata.org/wiki/Q192572","display_name":"In silico","level":3,"score":0.8441020250320435},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5027515888214111},{"id":"https://openalex.org/C2775842073","wikidata":"https://www.wikidata.org/wiki/Q208376","display_name":"Positron emission tomography","level":2,"score":0.4589269459247589},{"id":"https://openalex.org/C66024118","wikidata":"https://www.wikidata.org/wiki/Q1122506","display_name":"Computational model","level":2,"score":0.43108242750167847},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3874574303627014},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.31096938252449036},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2865878939628601},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2064756155014038},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1815587878227234},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.08932077884674072},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000860","descriptor_name":"Hypoxia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000860","descriptor_name":"Hypoxia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000860","descriptor_name":"Hypoxia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004058","descriptor_name":"Diffusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004058","descriptor_name":"Diffusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004058","descriptor_name":"Diffusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005947","descriptor_name":"Glucose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005947","descriptor_name":"Glucose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005947","descriptor_name":"Glucose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008920","descriptor_name":"Misonidazole","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D008920","descriptor_name":"Misonidazole","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D008920","descriptor_name":"Misonidazole","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D008962","descriptor_name":"Models, Theoretical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008962","descriptor_name":"Models, Theoretical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008962","descriptor_name":"Models, Theoretical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009389","descriptor_name":"Neovascularization, Pathologic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009389","descriptor_name":"Neovascularization, Pathologic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009389","descriptor_name":"Neovascularization, Pathologic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009942","descriptor_name":"Organometallic Compounds","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009942","descriptor_name":"Organometallic Compounds","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009942","descriptor_name":"Organometallic Compounds","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013882","descriptor_name":"Thiosemicarbazones","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013882","descriptor_name":"Thiosemicarbazones","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013882","descriptor_name":"Thiosemicarbazones","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015224","descriptor_name":"Dideoxynucleosides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015224","descriptor_name":"Dideoxynucleosides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015224","descriptor_name":"Dideoxynucleosides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019275","descriptor_name":"Radiopharmaceuticals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019275","descriptor_name":"Radiopharmaceuticals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019275","descriptor_name":"Radiopharmaceuticals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019788","descriptor_name":"Fluorodeoxyglucose F18","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019788","descriptor_name":"Fluorodeoxyglucose F18","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019788","descriptor_name":"Fluorodeoxyglucose F18","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049268","descriptor_name":"Positron-Emission Tomography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D049268","descriptor_name":"Positron-Emission Tomography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D049268","descriptor_name":"Positron-Emission Tomography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D056831","descriptor_name":"Coordination Complexes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056831","descriptor_name":"Coordination Complexes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056831","descriptor_name":"Coordination Complexes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064847","descriptor_name":"Multimodal Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064847","descriptor_name":"Multimodal Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064847","descriptor_name":"Multimodal Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1155/2015/415923","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2015/415923","pdf_url":"https://downloads.hindawi.com/journals/cmmm/2015/415923.pdf","source":{"id":"https://openalex.org/S36980176","display_name":"Computational and Mathematical Methods in Medicine","issn_l":"1748-670X","issn":["1748-670X","1748-6718"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869"],"host_organization_lineage_names":["Hindawi Publishing Corporation"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computational and Mathematical Methods in Medicine","raw_type":"journal-article"},{"id":"pmid:25788973","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25788973","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computational and mathematical methods in medicine","raw_type":null},{"id":"pmh:oai:urm_publish:9915989381401831","is_oa":true,"landing_page_url":"https://find.library.unisa.edu.au/discovery/fulldisplay/alma9915989381401831/61USOUTHAUS_INST:ROR","pdf_url":null,"source":{"id":"https://openalex.org/S4306402528","display_name":"UniSA Research Outputs Repository (University of South Australia)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I170239107","host_organization_name":"University of South Australia","host_organization_lineage":["https://openalex.org/I170239107"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"text"},{"id":"pmh:oai:digital.library.adelaide.edu.au:2440/99114","is_oa":true,"landing_page_url":"http://hdl.handle.net/2440/99114","pdf_url":null,"source":{"id":"https://openalex.org/S4306401835","display_name":"Adelaide Research & Scholarship (AR&S) (University of Adelaide)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I5681781","host_organization_name":"The University of Adelaide","host_organization_lineage":["https://openalex.org/I5681781"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://dx.doi.org/10.1155/2015/415923","raw_type":"Journal article"},{"id":"pmh:oai:doaj.org/article:fbccf1e434cb4e90ab42a7401a623661","is_oa":true,"landing_page_url":"https://doaj.org/article/fbccf1e434cb4e90ab42a7401a623661","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Computational and Mathematical Methods in Medicine, Vol 2015 (2015)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4350968","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4350968","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Comput Math Methods Med","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1155/2015/415923","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2015/415923","pdf_url":"https://downloads.hindawi.com/journals/cmmm/2015/415923.pdf","source":{"id":"https://openalex.org/S36980176","display_name":"Computational and Mathematical Methods in Medicine","issn_l":"1748-670X","issn":["1748-670X","1748-6718"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869"],"host_organization_lineage_names":["Hindawi Publishing Corporation"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computational and Mathematical Methods in Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/9","display_name":"Industry, innovation and infrastructure","score":0.5}],"awards":[{"id":"https://openalex.org/G5350906703","display_name":null,"funder_award_id":"PN-II-ID-PCE-2012-4-0067","funder_id":"https://openalex.org/F4320334927","funder_display_name":"Consiliul National al Cercetarii Stiintifice"}],"funders":[{"id":"https://openalex.org/F4320323983","display_name":"Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii","ror":"https://ror.org/01q7jq182"},{"id":"https://openalex.org/F4320334927","display_name":"Consiliul National al Cercetarii Stiintifice","ror":"https://ror.org/035rrps97"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2061985730.pdf","grobid_xml":"https://content.openalex.org/works/W2061985730.grobid-xml"},"referenced_works_count":74,"referenced_works":["https://openalex.org/W254685626","https://openalex.org/W604750464","https://openalex.org/W1482608649","https://openalex.org/W1493048246","https://openalex.org/W1777438515","https://openalex.org/W1848872330","https://openalex.org/W1899213880","https://openalex.org/W1899386968","https://openalex.org/W1914839904","https://openalex.org/W1919207554","https://openalex.org/W1955605225","https://openalex.org/W1957137659","https://openalex.org/W1970708137","https://openalex.org/W1971093463","https://openalex.org/W1973556463","https://openalex.org/W1979306998","https://openalex.org/W1979538859","https://openalex.org/W1980242505","https://openalex.org/W1987846933","https://openalex.org/W1990186831","https://openalex.org/W2000769939","https://openalex.org/W2006067863","https://openalex.org/W2006519442","https://openalex.org/W2012534378","https://openalex.org/W2013373169","https://openalex.org/W2016550302","https://openalex.org/W2022702208","https://openalex.org/W2031464563","https://openalex.org/W2032022462","https://openalex.org/W2036294216","https://openalex.org/W2036622441","https://openalex.org/W2038751328","https://openalex.org/W2043187527","https://openalex.org/W2044257143","https://openalex.org/W2045434770","https://openalex.org/W2048619131","https://openalex.org/W2050657868","https://openalex.org/W2050791255","https://openalex.org/W2051708290","https://openalex.org/W2057343401","https://openalex.org/W2057770669","https://openalex.org/W2064638766","https://openalex.org/W2080386114","https://openalex.org/W2085319321","https://openalex.org/W2091231028","https://openalex.org/W2096719319","https://openalex.org/W2097598171","https://openalex.org/W2099676413","https://openalex.org/W2103862270","https://openalex.org/W2109242569","https://openalex.org/W2109924906","https://openalex.org/W2110881080","https://openalex.org/W2111081063","https://openalex.org/W2114378747","https://openalex.org/W2118170166","https://openalex.org/W2118604693","https://openalex.org/W2127886703","https://openalex.org/W2131608790","https://openalex.org/W2131831965","https://openalex.org/W2138509761","https://openalex.org/W2142171814","https://openalex.org/W2148758804","https://openalex.org/W2150992047","https://openalex.org/W2155797861","https://openalex.org/W2158515198","https://openalex.org/W2164675518","https://openalex.org/W2166071433","https://openalex.org/W2166921825","https://openalex.org/W2181590055","https://openalex.org/W2185163645","https://openalex.org/W2239752656","https://openalex.org/W2411873605","https://openalex.org/W3089669417","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2513589746","https://openalex.org/W2153919606","https://openalex.org/W2003194288","https://openalex.org/W2213189664","https://openalex.org/W2074002899","https://openalex.org/W2062254828","https://openalex.org/W4237480606","https://openalex.org/W2936968863","https://openalex.org/W1971792277","https://openalex.org/W3026240506"],"abstract_inverted_index":{"The":[0,140,169],"innovation":[1],"of":[2,14,21,38,93,109,128,185],"computational":[3],"techniques":[4],"serves":[5],"as":[6,102,153,155],"an":[7],"important":[8],"step":[9],"toward":[10],"optimized,":[11],"patient-specific":[12],"management":[13],"cancer.":[15],"In":[16,52,67,123],"particular,":[17,68],"in":[18,84,116,133,134,186],"silico":[19,53,135,187],"simulation":[20],"tumour":[22,73,88,99,117,136],"growth":[23],"and":[24,41,65,78,104,111,130,149,167,176,197],"treatment":[25],"response":[26],"may":[27,159],"eventually":[28],"yield":[29],"accurate":[30],"information":[31,61,132],"on":[32],"disease":[33],"progression,":[34],"enhance":[35],"the":[36,91,107,126,156],"quality":[37],"cancer":[39],"treatment,":[40],"explain":[42],"why":[43],"certain":[44],"therapies":[45],"are":[46,50,151,179],"effective":[47],"where":[48],"others":[49],"not.":[51],"modelling":[54],"is":[55,138,195],"demonstrated":[56],"to":[57,86,96,121,173],"considerably":[58],"benefit":[59],"from":[60,81],"obtainable":[62],"with":[63],"PET":[64,110,129,148,175,191],"PET/CT.":[66],"models":[69,118,137,188],"have":[70],"successfully":[71],"integrated":[72],"glucose":[74],"metabolism,":[75],"cell":[76,79],"proliferation,":[77],"oxygenation":[80],"multiple":[82],"tracers":[83],"order":[85],"simulate":[87],"behaviour.":[89],"With":[90],"development":[92],"novel":[94],"radiotracers":[95,157],"image":[97],"additional":[98],"phenomena,":[100],"such":[101],"pH":[103],"gene":[105],"expression,":[106],"value":[108],"PET/CT":[112,131,150,177,193],"data":[113,178,194],"for":[114,162],"use":[115,127],"will":[119],"continue":[120],"grow.":[122],"this":[124,163],"work,":[125],"reviewed.":[139,198],"various":[141],"parameters":[142],"that":[143,158,189],"can":[144],"be":[145,160],"obtained":[146],"using":[147],"detailed,":[152],"well":[154],"used":[161,172],"purpose,":[164],"their":[165],"utility,":[166],"limitations.":[168],"biophysical":[170],"measures":[171],"quantify":[174],"also":[180],"described.":[181],"Finally,":[182],"a":[183],"list":[184],"incorporate":[190],"and/or":[192],"provided":[196]},"counts_by_year":[{"year":2023,"cited_by_count":5},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2}],"updated_date":"2026-03-20T23:20:44.827607","created_date":"2016-06-24T00:00:00"}