{"id":"https://openalex.org/W1983615320","doi":"https://doi.org/10.1155/2012/781456","title":"Coarse-Grained Simulation of Myosin-V Movement","display_name":"Coarse-Grained Simulation of Myosin-V Movement","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W1983615320","doi":"https://doi.org/10.1155/2012/781456","mag":"1983615320","pmid":"https://pubmed.ncbi.nlm.nih.gov/22675402"},"language":"en","primary_location":{"id":"doi:10.1155/2012/781456","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2012/781456","pdf_url":"https://downloads.hindawi.com/journals/cmmm/2012/781456.pdf","source":{"id":"https://openalex.org/S36980176","display_name":"Computational and Mathematical Methods in Medicine","issn_l":"1748-670X","issn":["1748-670X","1748-6718"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869"],"host_organization_lineage_names":["Hindawi Publishing Corporation"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computational and Mathematical Methods in Medicine","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://downloads.hindawi.com/journals/cmmm/2012/781456.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049073511","display_name":"Zoe Katsimitsoulia","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zoe Katsimitsoulia","raw_affiliation_strings":["Division of Mathematical Biology, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Mathematical Biology, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5001813503","display_name":"William R. Taylor","orcid":"https://orcid.org/0000-0002-2798-9600"},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"William R. Taylor","raw_affiliation_strings":["Division of Mathematical Biology, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Mathematical Biology, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5001813503"],"corresponding_institution_ids":[],"apc_list":{"value":2100,"currency":"USD","value_usd":2100},"apc_paid":{"value":2100,"currency":"USD","value_usd":2100},"fwci":0.0,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.07865644,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"2012","issue":null,"first_page":"1","last_page":"15"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics","score":0.9882000088691711,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10923","display_name":"Force Microscopy Techniques and Applications","score":0.9876000285148621,"subfield":{"id":"https://openalex.org/subfields/3107","display_name":"Atomic and Molecular Physics, and Optics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/myosin","display_name":"Myosin","score":0.8031293153762817},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5974870324134827},{"id":"https://openalex.org/keywords/bounding-overwatch","display_name":"Bounding overwatch","score":0.5787883400917053},{"id":"https://openalex.org/keywords/protein-filament","display_name":"Protein filament","score":0.543552815914154},{"id":"https://openalex.org/keywords/actin","display_name":"Actin","score":0.5354378819465637},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.5284010171890259},{"id":"https://openalex.org/keywords/motor-protein","display_name":"Motor protein","score":0.4992959499359131},{"id":"https://openalex.org/keywords/domain","display_name":"Domain (mathematical analysis)","score":0.4548214077949524},{"id":"https://openalex.org/keywords/tree","display_name":"Tree (set theory)","score":0.44988635182380676},{"id":"https://openalex.org/keywords/molecular-motor","display_name":"Molecular motor","score":0.41628116369247437},{"id":"https://openalex.org/keywords/biophysics","display_name":"Biophysics","score":0.34476351737976074},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.24395453929901123},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2011183798313141},{"id":"https://openalex.org/keywords/microtubule","display_name":"Microtubule","score":0.1548195779323578},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.1455920934677124},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.12222516536712646}],"concepts":[{"id":"https://openalex.org/C6997183","wikidata":"https://www.wikidata.org/wiki/Q271727","display_name":"Myosin","level":2,"score":0.8031293153762817},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5974870324134827},{"id":"https://openalex.org/C63584917","wikidata":"https://www.wikidata.org/wiki/Q333286","display_name":"Bounding overwatch","level":2,"score":0.5787883400917053},{"id":"https://openalex.org/C14228908","wikidata":"https://www.wikidata.org/wiki/Q2920483","display_name":"Protein filament","level":2,"score":0.543552815914154},{"id":"https://openalex.org/C125705527","wikidata":"https://www.wikidata.org/wiki/Q185269","display_name":"Actin","level":2,"score":0.5354378819465637},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.5284010171890259},{"id":"https://openalex.org/C93126451","wikidata":"https://www.wikidata.org/wiki/Q2383767","display_name":"Motor protein","level":3,"score":0.4992959499359131},{"id":"https://openalex.org/C36503486","wikidata":"https://www.wikidata.org/wiki/Q11235244","display_name":"Domain (mathematical analysis)","level":2,"score":0.4548214077949524},{"id":"https://openalex.org/C113174947","wikidata":"https://www.wikidata.org/wiki/Q2859736","display_name":"Tree (set theory)","level":2,"score":0.44988635182380676},{"id":"https://openalex.org/C160408235","wikidata":"https://www.wikidata.org/wiki/Q423905","display_name":"Molecular motor","level":2,"score":0.41628116369247437},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.34476351737976074},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.24395453929901123},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2011183798313141},{"id":"https://openalex.org/C20418707","wikidata":"https://www.wikidata.org/wiki/Q189933","display_name":"Microtubule","level":2,"score":0.1548195779323578},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.1455920934677124},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.12222516536712646},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.0},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008841","descriptor_name":"Actin Cytoskeleton","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008841","descriptor_name":"Actin Cytoskeleton","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008841","descriptor_name":"Actin Cytoskeleton","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008841","descriptor_name":"Actin Cytoskeleton","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008841","descriptor_name":"Actin Cytoskeleton","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008841","descriptor_name":"Actin Cytoskeleton","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009068","descriptor_name":"Movement","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009068","descriptor_name":"Movement","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009068","descriptor_name":"Movement","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019281","descriptor_name":"Dimerization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019281","descriptor_name":"Dimerization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019281","descriptor_name":"Dimerization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020409","descriptor_name":"Molecular Motor Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D020409","descriptor_name":"Molecular Motor Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D020409","descriptor_name":"Molecular Motor Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D020409","descriptor_name":"Molecular Motor Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D020409","descriptor_name":"Molecular Motor Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D020409","descriptor_name":"Molecular Motor Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D024701","descriptor_name":"Myosin Type V","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D024701","descriptor_name":"Myosin Type V","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D024701","descriptor_name":"Myosin Type V","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D024701","descriptor_name":"Myosin Type V","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D024701","descriptor_name":"Myosin Type V","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D024701","descriptor_name":"Myosin Type V","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D056004","descriptor_name":"Molecular Dynamics Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056004","descriptor_name":"Molecular Dynamics Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056004","descriptor_name":"Molecular Dynamics Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1155/2012/781456","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2012/781456","pdf_url":"https://downloads.hindawi.com/journals/cmmm/2012/781456.pdf","source":{"id":"https://openalex.org/S36980176","display_name":"Computational and Mathematical Methods in Medicine","issn_l":"1748-670X","issn":["1748-670X","1748-6718"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869"],"host_organization_lineage_names":["Hindawi Publishing Corporation"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computational and Mathematical Methods in Medicine","raw_type":"journal-article"},{"id":"pmid:22675402","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22675402","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computational and mathematical methods in medicine","raw_type":null},{"id":"pmh:oai:doaj.org/article:e23313bc933944a49580ff8a2cf3779b","is_oa":false,"landing_page_url":"https://doaj.org/article/e23313bc933944a49580ff8a2cf3779b","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Computational and Mathematical Methods in Medicine, Vol 2012 (2012)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:2375674","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3366208","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1155/2012/781456","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2012/781456","pdf_url":"https://downloads.hindawi.com/journals/cmmm/2012/781456.pdf","source":{"id":"https://openalex.org/S36980176","display_name":"Computational and Mathematical Methods in Medicine","issn_l":"1748-670X","issn":["1748-670X","1748-6718"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869"],"host_organization_lineage_names":["Hindawi Publishing Corporation"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computational and Mathematical Methods in Medicine","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G8656091","display_name":null,"funder_award_id":"U117581331","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"}],"funders":[{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1983615320.pdf","grobid_xml":"https://content.openalex.org/works/W1983615320.grobid-xml"},"referenced_works_count":28,"referenced_works":["https://openalex.org/W1541004785","https://openalex.org/W1843431848","https://openalex.org/W1978243335","https://openalex.org/W1979935867","https://openalex.org/W1980676208","https://openalex.org/W1995035844","https://openalex.org/W2001758775","https://openalex.org/W2005216750","https://openalex.org/W2015404233","https://openalex.org/W2025039463","https://openalex.org/W2033350330","https://openalex.org/W2043226544","https://openalex.org/W2043621939","https://openalex.org/W2045339499","https://openalex.org/W2047093393","https://openalex.org/W2050344045","https://openalex.org/W2055665417","https://openalex.org/W2064286990","https://openalex.org/W2069562541","https://openalex.org/W2073965063","https://openalex.org/W2084606589","https://openalex.org/W2085239860","https://openalex.org/W2095559982","https://openalex.org/W2106145031","https://openalex.org/W2123999164","https://openalex.org/W2138327991","https://openalex.org/W2140972301","https://openalex.org/W2170296662"],"related_works":["https://openalex.org/W4210899924","https://openalex.org/W2005620429","https://openalex.org/W2055027542","https://openalex.org/W1981068779","https://openalex.org/W2056204461","https://openalex.org/W2763658086","https://openalex.org/W2091801252","https://openalex.org/W2036547507","https://openalex.org/W2531115716","https://openalex.org/W2048734312"],"abstract_inverted_index":{"We":[0,111],"describe":[1],"the":[2,12,16,27,45,52,57,62,83,106,113,121,140],"development":[3],"of":[4,15,33,47,54,61,69,99,108,123,143],"a":[5,67,97],"hierarchic":[6,28,84],"modelling":[7],"method":[8],"applied":[9,78],"to":[10,51,79,96,139],"simulating":[11],"processive":[13],"movement":[14],"myosin-V":[17,144],"molecular":[18],"motor":[19],"protein":[20,34],"along":[21],"an":[22,80],"actin":[23],"filament":[24],"track.":[25],"In":[26],"model,":[29,128],"three":[30],"different":[31],"levels":[32],"structure":[35],"resolution":[36],"are":[37],"represented:":[38],"secondary":[39],"structure,":[40],"domain,":[41],"and":[42,74,119,133],"protein,":[43],"with":[44,116],"level":[46],"detail":[48,125],"changing":[49],"according":[50],"degree":[53],"interaction":[55],"among":[56],"molecules.":[58],"The":[59],"integrity":[60],"system":[63],"is":[64,86],"maintained":[65],"using":[66],"tree":[68],"spatially":[70],"organised":[71],"bounding":[72],"volumes":[73],"distance":[75],"constraints.":[76],"Although":[77],"actin-myosin":[81],"system,":[82],"framework":[85],"general":[87],"enough":[88],"so":[89],"that":[90],"it":[91],"may":[92],"easily":[93],"be":[94],"adapted":[95],"number":[98],"other":[100],"large":[101],"biomolecular":[102],"systems":[103],"containing":[104],"in":[105,126],"order":[107],"100":[109],"proteins.":[110],"compared":[112],"simulation":[114],"results":[115],"biophysical":[117],"data,":[118],"despite":[120],"lack":[122],"atomic":[124],"our":[127],"we":[129],"find":[130],"good":[131],"agreement":[132],"can":[134],"even":[135],"suggest":[136],"some":[137],"refinements":[138],"current":[141],"model":[142],"motion.":[145]},"counts_by_year":[{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2025-10-10T00:00:00"}