{"id":"https://openalex.org/W2085990641","doi":"https://doi.org/10.1155/2011/572876","title":"Inference of Kinetic Parameters of Delayed Stochastic Models of Gene Expression Using a Markov Chain Approximation","display_name":"Inference of Kinetic Parameters of Delayed Stochastic Models of Gene Expression Using a Markov Chain Approximation","publication_year":2010,"publication_date":"2010-12-29","ids":{"openalex":"https://openalex.org/W2085990641","doi":"https://doi.org/10.1155/2011/572876","mag":"2085990641","pmid":"https://pubmed.ncbi.nlm.nih.gov/21234243"},"language":"en","primary_location":{"id":"doi:10.1155/2011/572876","is_oa":false,"landing_page_url":"https://doi.org/10.1155/2011/572876","pdf_url":null,"source":{"id":"https://openalex.org/S22696228","display_name":"EURASIP Journal on Bioinformatics and Systems Biology","issn_l":"1687-4145","issn":["1687-4145","1687-4153"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EURASIP Journal on Bioinformatics and Systems Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3171302","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070900340","display_name":"Henrik Mannerstr\u00f6m","orcid":"https://orcid.org/0000-0001-8492-665X"},"institutions":[{"id":"https://openalex.org/I4210133110","display_name":"Tampere University","ror":null,"country_code":"FI","type":null,"lineage":["https://openalex.org/I4210133110"]}],"countries":["FI"],"is_corresponding":true,"raw_author_name":"Henrik Mannerstrom","raw_affiliation_strings":["Computational Systems Biology Research Group, Department of Signal Processing, Tampere University of Technology, P.O. Box 553, 33101 Tampere, Finland","[Department of Signal Processing, Tampere University of Technology, Tampere, FINLAND]"],"affiliations":[{"raw_affiliation_string":"Computational Systems Biology Research Group, Department of Signal Processing, Tampere University of Technology, P.O. Box 553, 33101 Tampere, Finland","institution_ids":["https://openalex.org/I4210133110"]},{"raw_affiliation_string":"[Department of Signal Processing, Tampere University of Technology, Tampere, FINLAND]","institution_ids":["https://openalex.org/I4210133110"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026230936","display_name":"Olli Yli\u2010Harja","orcid":"https://orcid.org/0000-0001-8581-4414"},"institutions":[{"id":"https://openalex.org/I166825849","display_name":"Tampere University","ror":"https://ror.org/033003e23","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849"]},{"id":"https://openalex.org/I3148997608","display_name":"Institute for Systems Biology","ror":"https://ror.org/02tpgw303","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I3148997608"]},{"id":"https://openalex.org/I4210121626","display_name":"Signal Processing (United States)","ror":"https://ror.org/021gzyw51","country_code":"US","type":"company","lineage":["https://openalex.org/I4210121626"]},{"id":"https://openalex.org/I4210133110","display_name":"Tampere University","ror":null,"country_code":"FI","type":null,"lineage":["https://openalex.org/I4210133110"]}],"countries":["FI","US"],"is_corresponding":false,"raw_author_name":"Olli Yli-Harja","raw_affiliation_strings":["Department of Signal Processing, Tampere University of Technology, Tampere, Finland and Institute for Systems Biology, Seattle, WA#TAB#"],"affiliations":[{"raw_affiliation_string":"Department of Signal Processing, Tampere University of Technology, Tampere, Finland and Institute for Systems Biology, Seattle, WA#TAB#","institution_ids":["https://openalex.org/I3148997608","https://openalex.org/I166825849","https://openalex.org/I4210121626","https://openalex.org/I4210133110"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5040628945","display_name":"Andr\u00e9 S. Ribeiro","orcid":"https://orcid.org/0000-0002-7255-5211"},"institutions":[{"id":"https://openalex.org/I4210133110","display_name":"Tampere University","ror":null,"country_code":"FI","type":null,"lineage":["https://openalex.org/I4210133110"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Andre S Ribeiro","raw_affiliation_strings":["[Department of Signal Processing, Tampere University of Technology, Tampere, FINLAND]"],"affiliations":[{"raw_affiliation_string":"[Department of Signal Processing, Tampere University of Technology, Tampere, FINLAND]","institution_ids":["https://openalex.org/I4210133110"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5070900340"],"corresponding_institution_ids":["https://openalex.org/I4210133110"],"apc_list":null,"apc_paid":null,"fwci":0.1355,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.544988,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"2011","issue":"1","first_page":"572876","last_page":"572876"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9962999820709229,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/markov-chain","display_name":"Markov chain","score":0.6398057341575623},{"id":"https://openalex.org/keywords/inference","display_name":"Inference","score":0.6094426512718201},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5400903820991516},{"id":"https://openalex.org/keywords/transcription","display_name":"Transcription (linguistics)","score":0.5147059559822083},{"id":"https://openalex.org/keywords/rna","display_name":"RNA","score":0.47659987211227417},{"id":"https://openalex.org/keywords/stochastic-modelling","display_name":"Stochastic modelling","score":0.45473864674568176},{"id":"https://openalex.org/keywords/stochastic-process","display_name":"Stochastic process","score":0.4164885878562927},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.378833144903183},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.33738577365875244},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.28559625148773193},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.2699369490146637},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.2463061511516571},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.18091344833374023},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.16522762179374695},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.1632598340511322},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.10995638370513916}],"concepts":[{"id":"https://openalex.org/C98763669","wikidata":"https://www.wikidata.org/wiki/Q176645","display_name":"Markov chain","level":2,"score":0.6398057341575623},{"id":"https://openalex.org/C2776214188","wikidata":"https://www.wikidata.org/wiki/Q408386","display_name":"Inference","level":2,"score":0.6094426512718201},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5400903820991516},{"id":"https://openalex.org/C179926584","wikidata":"https://www.wikidata.org/wiki/Q207714","display_name":"Transcription (linguistics)","level":2,"score":0.5147059559822083},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.47659987211227417},{"id":"https://openalex.org/C127491075","wikidata":"https://www.wikidata.org/wiki/Q7617825","display_name":"Stochastic modelling","level":2,"score":0.45473864674568176},{"id":"https://openalex.org/C8272713","wikidata":"https://www.wikidata.org/wiki/Q176737","display_name":"Stochastic process","level":2,"score":0.4164885878562927},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.378833144903183},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.33738577365875244},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.28559625148773193},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.2699369490146637},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2463061511516571},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.18091344833374023},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.16522762179374695},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1632598340511322},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.10995638370513916},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1155/2011/572876","is_oa":false,"landing_page_url":"https://doi.org/10.1155/2011/572876","pdf_url":null,"source":{"id":"https://openalex.org/S22696228","display_name":"EURASIP Journal on Bioinformatics and Systems Biology","issn_l":"1687-4145","issn":["1687-4145","1687-4153"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EURASIP Journal on Bioinformatics and Systems Biology","raw_type":"journal-article"},{"id":"pmid:21234243","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21234243","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EURASIP journal on bioinformatics & systems biology","raw_type":null},{"id":"pmh:oai:europepmc.org:2177001","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3171302","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2177001","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3171302","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321855","display_name":"Tekes","ror":"https://ror.org/02ag8cq23"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W1681969670","https://openalex.org/W1968856189","https://openalex.org/W1978182054","https://openalex.org/W1980879384","https://openalex.org/W1984217390","https://openalex.org/W1996691828","https://openalex.org/W2011097028","https://openalex.org/W2024498258","https://openalex.org/W2026888821","https://openalex.org/W2049222491","https://openalex.org/W2062029454","https://openalex.org/W2062404235","https://openalex.org/W2091198609","https://openalex.org/W2093470850","https://openalex.org/W2118274513","https://openalex.org/W2134440848","https://openalex.org/W2155418451","https://openalex.org/W2167244112","https://openalex.org/W2167543722","https://openalex.org/W2170467788"],"related_works":["https://openalex.org/W1995427843","https://openalex.org/W2042280983","https://openalex.org/W2888652631","https://openalex.org/W2321888438","https://openalex.org/W2369445029","https://openalex.org/W2026456043","https://openalex.org/W4320063126","https://openalex.org/W2417662900","https://openalex.org/W1987284827","https://openalex.org/W1996323220"],"abstract_inverted_index":null,"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-04-21T08:09:41.155169","created_date":"2025-10-10T00:00:00"}