{"id":"https://openalex.org/W4392255498","doi":"https://doi.org/10.1145/3637732.3637789","title":"Nonlinear Assessment of Cerebral Autoregulation and Analysis of Cardiorespiratory Signals in Patients with Diabetes Mellitus under Head-up Tilt Test","display_name":"Nonlinear Assessment of Cerebral Autoregulation and Analysis of Cardiorespiratory Signals in Patients with Diabetes Mellitus under Head-up Tilt Test","publication_year":2023,"publication_date":"2023-11-09","ids":{"openalex":"https://openalex.org/W4392255498","doi":"https://doi.org/10.1145/3637732.3637789"},"language":"en","primary_location":{"id":"doi:10.1145/3637732.3637789","is_oa":true,"landing_page_url":"https://doi.org/10.1145/3637732.3637789","pdf_url":"https://dl.acm.org/doi/pdf/10.1145/3637732.3637789","source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 2023 10th International Conference on Biomedical and Bioinformatics Engineering","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://dl.acm.org/doi/pdf/10.1145/3637732.3637789","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090910395","display_name":"Shyan\u2010Lung Lin","orcid":"https://orcid.org/0000-0001-6316-4297"},"institutions":[{"id":"https://openalex.org/I4880106","display_name":"Feng Chia University","ror":"https://ror.org/05vhczg54","country_code":"TW","type":"education","lineage":["https://openalex.org/I4880106"]}],"countries":["TW"],"is_corresponding":true,"raw_author_name":"Shyan-Lung Lin","raw_affiliation_strings":["Department of Automatic Control Engineering, Feng Chia University, Taiwan"],"raw_orcid":"https://orcid.org/0000-0001-6316-4297","affiliations":[{"raw_affiliation_string":"Department of Automatic Control Engineering, Feng Chia University, Taiwan","institution_ids":["https://openalex.org/I4880106"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108036391","display_name":"Shoou-Jeng Yeh","orcid":"https://orcid.org/0000-0002-8717-3689"},"institutions":[{"id":"https://openalex.org/I4880106","display_name":"Feng Chia University","ror":"https://ror.org/05vhczg54","country_code":"TW","type":"education","lineage":["https://openalex.org/I4880106"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Shoou-Jeng Yeh","raw_affiliation_strings":["Department of Automatic Control Engineering, Feng Chia University, Taiwan"],"raw_orcid":"https://orcid.org/0000-0002-8717-3689","affiliations":[{"raw_affiliation_string":"Department of Automatic Control Engineering, Feng Chia University, Taiwan","institution_ids":["https://openalex.org/I4880106"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087199019","display_name":"Ching\u2010Kun Chen","orcid":"https://orcid.org/0000-0003-4156-442X"},"institutions":[{"id":"https://openalex.org/I4880106","display_name":"Feng Chia University","ror":"https://ror.org/05vhczg54","country_code":"TW","type":"education","lineage":["https://openalex.org/I4880106"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Ching-Kun Chen","raw_affiliation_strings":["Department of Automatic Control Engineering, Feng Chia University, Taiwan"],"raw_orcid":"https://orcid.org/0000-0003-4156-442X","affiliations":[{"raw_affiliation_string":"Department of Automatic Control Engineering, Feng Chia University, Taiwan","institution_ids":["https://openalex.org/I4880106"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101552210","display_name":"Chung-Chieh Lo","orcid":"https://orcid.org/0009-0006-9449-6503"},"institutions":[{"id":"https://openalex.org/I4880106","display_name":"Feng Chia University","ror":"https://ror.org/05vhczg54","country_code":"TW","type":"education","lineage":["https://openalex.org/I4880106"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chung-Chieh Lo","raw_affiliation_strings":["Department of Automatic Control Engineering, Feng Chia University, Taiwan"],"raw_orcid":"https://orcid.org/0009-0006-9449-6503","affiliations":[{"raw_affiliation_string":"Department of Automatic Control Engineering, Feng Chia University, Taiwan","institution_ids":["https://openalex.org/I4880106"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5090910395"],"corresponding_institution_ids":["https://openalex.org/I4880106"],"apc_list":null,"apc_paid":null,"fwci":0.4271,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.69228076,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":96},"biblio":{"volume":null,"issue":null,"first_page":"135","last_page":"140"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10977","display_name":"Optical Imaging and Spectroscopy Techniques","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10924","display_name":"Cardiovascular Health and Disease Prevention","score":0.9957000017166138,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cerebral-autoregulation","display_name":"Cerebral autoregulation","score":0.6719975471496582},{"id":"https://openalex.org/keywords/supine-position","display_name":"Supine position","score":0.6493439078330994},{"id":"https://openalex.org/keywords/cerebral-blood-flow","display_name":"Cerebral blood flow","score":0.5976578593254089},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.5717766284942627},{"id":"https://openalex.org/keywords/cardiology","display_name":"Cardiology","score":0.5521001815795898},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.5171415209770203},{"id":"https://openalex.org/keywords/cardiorespiratory-fitness","display_name":"Cardiorespiratory fitness","score":0.5168209671974182},{"id":"https://openalex.org/keywords/hyperventilation","display_name":"Hyperventilation","score":0.48555895686149597},{"id":"https://openalex.org/keywords/blood-pressure","display_name":"Blood pressure","score":0.46640363335609436},{"id":"https://openalex.org/keywords/autoregulation","display_name":"Autoregulation","score":0.40268248319625854}],"concepts":[{"id":"https://openalex.org/C84359808","wikidata":"https://www.wikidata.org/wiki/Q13365173","display_name":"Cerebral autoregulation","level":4,"score":0.6719975471496582},{"id":"https://openalex.org/C125567185","wikidata":"https://www.wikidata.org/wiki/Q3267428","display_name":"Supine position","level":2,"score":0.6493439078330994},{"id":"https://openalex.org/C157767197","wikidata":"https://www.wikidata.org/wiki/Q886843","display_name":"Cerebral blood flow","level":2,"score":0.5976578593254089},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5717766284942627},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5521001815795898},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5171415209770203},{"id":"https://openalex.org/C117437137","wikidata":"https://www.wikidata.org/wiki/Q5038720","display_name":"Cardiorespiratory fitness","level":2,"score":0.5168209671974182},{"id":"https://openalex.org/C2777449187","wikidata":"https://www.wikidata.org/wiki/Q575168","display_name":"Hyperventilation","level":2,"score":0.48555895686149597},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.46640363335609436},{"id":"https://openalex.org/C111774379","wikidata":"https://www.wikidata.org/wiki/Q1364253","display_name":"Autoregulation","level":3,"score":0.40268248319625854}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1145/3637732.3637789","is_oa":true,"landing_page_url":"https://doi.org/10.1145/3637732.3637789","pdf_url":"https://dl.acm.org/doi/pdf/10.1145/3637732.3637789","source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 2023 10th International Conference on Biomedical and Bioinformatics Engineering","raw_type":"proceedings-article"}],"best_oa_location":{"id":"doi:10.1145/3637732.3637789","is_oa":true,"landing_page_url":"https://doi.org/10.1145/3637732.3637789","pdf_url":"https://dl.acm.org/doi/pdf/10.1145/3637732.3637789","source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 2023 10th International Conference on Biomedical and Bioinformatics Engineering","raw_type":"proceedings-article"},"sustainable_development_goals":[{"display_name":"Clean water and sanitation","score":0.6000000238418579,"id":"https://metadata.un.org/sdg/6"}],"awards":[{"id":"https://openalex.org/G7229444857","display_name":null,"funder_award_id":"NSTC 112-2629-E-035-001","funder_id":"https://openalex.org/F4320323817","funder_display_name":"Universitas Brawijaya"}],"funders":[{"id":"https://openalex.org/F4320323817","display_name":"Universitas Brawijaya","ror":"https://ror.org/01wk3d929"},{"id":"https://openalex.org/F4320331164","display_name":"National Science and Technology Council","ror":"https://ror.org/00wnb9798"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4392255498.pdf","grobid_xml":"https://content.openalex.org/works/W4392255498.grobid-xml"},"referenced_works_count":13,"referenced_works":["https://openalex.org/W105412379","https://openalex.org/W1970902987","https://openalex.org/W1978043326","https://openalex.org/W2030466802","https://openalex.org/W2092176916","https://openalex.org/W2115398282","https://openalex.org/W2131174847","https://openalex.org/W2153425956","https://openalex.org/W2160694091","https://openalex.org/W2164650922","https://openalex.org/W2167993960","https://openalex.org/W2271644972","https://openalex.org/W3111764673"],"related_works":["https://openalex.org/W1975908581","https://openalex.org/W2664729653","https://openalex.org/W2314201917","https://openalex.org/W2913395717","https://openalex.org/W2811446807","https://openalex.org/W2177576479","https://openalex.org/W2327464601","https://openalex.org/W2086441951","https://openalex.org/W3136876934","https://openalex.org/W4295924926"],"abstract_inverted_index":{"It":[0],"has":[1,31,44],"been":[2],"known":[3],"that":[4,147,170],"the":[5,33,56,98,148,166],"relationship":[6,168],"between":[7],"arterial":[8,24],"CO2":[9,38,132],"and":[10,18,70,91,112,114,118,131,138,155,182,189,192],"cerebral":[11],"blood":[12,25],"flow":[13],"velocity":[14],"(CBFV)":[15],"is":[16],"nonlinear":[17,34,127,163],"affected":[19],"by":[20],"CO2-induced":[21],"changes":[22],"in":[23,133,175,190],"pressure":[26,86],"(ABP).":[27],"However,":[28],"no":[29],"study":[30],"examined":[32],"cerebrovascular":[35],"response":[36],"to":[37],"for":[39,50,122],"diabetes":[40],"mellitus":[41],"(DM),":[42],"which":[43],"become":[45],"a":[46],"significant":[47,173],"risk":[48],"factor":[49],"cardiovascular":[51],"disease.":[52],"In":[53],"this":[54],"paper,":[55],"head-up":[57],"tilt":[58],"table":[59],"(HUT)":[60],"experiment":[61,124,145],"was":[62,135],"performed":[63],"with":[64,140,186,196],"three":[65,123],"stages:":[66],"supine":[67],"resting,":[68],"hyperventilation,":[69],"75\u00b0":[71],"upright":[72],"positions.":[73],"The":[74,100,126,143,162],"subject's":[75],"cardiorespiratory":[76],"signals,":[77],"including":[78],"CBFV,":[79,153],"ABP,":[80,152],"heart":[81],"rate":[82],"(HR),":[83],"end-tidal":[84],"partial":[85],"of":[87,107,129,165,178],"carbon":[88],"dioxide":[89],"(PETCO2),":[90],"airflow,":[92],"were":[93,103,115],"all":[94],"recorded":[95],"continuously":[96],"throughout":[97],"experiment.":[99],"subject":[101],"data":[102],"classified":[104],"into":[105],"groups":[106,121],"normal":[108,110,141,160,187,197],"elders,":[109,188],"youths,":[111],"DM,":[113],"further":[116,136],"analyzed":[117],"compared":[119,139,185,195],"among":[120],"stages.":[125],"interaction":[128],"CBFV":[130],"DM":[134,149,171],"assessed":[137],"subjects.":[142,161],"HUT":[144],"showed":[146,169],"group's":[150],"mean":[151],"HR,":[154],"PETCO2":[156],"significantly":[157],"differed":[158],"from":[159],"assessment":[164],"CBFV-PETCO2":[167],"demonstrates":[172],"differences":[174],"sigmoid":[176],"parameters":[177],"range,":[179],"curvilinear,":[180],"mid-PETCO2,":[181],"CBFVmax":[183],"as":[184,194],"curvilinear":[191],"mid-PETCO2":[193],"youths.":[198]},"counts_by_year":[{"year":2025,"cited_by_count":2}],"updated_date":"2026-03-27T05:58:40.876381","created_date":"2025-10-10T00:00:00"}