{"id":"https://openalex.org/W7170496102","doi":"https://doi.org/10.1145/3807503.3819448","title":"Auditing Retrieval-Augmented LLM Hypotheses for Longitudinal Cell Painting Morphology","display_name":"Auditing Retrieval-Augmented LLM Hypotheses for Longitudinal Cell Painting Morphology","publication_year":2026,"publication_date":"2026-06-30","ids":{"openalex":"https://openalex.org/W7170496102","doi":"https://doi.org/10.1145/3807503.3819448"},"language":null,"primary_location":{"id":"doi:10.1145/3807503.3819448","is_oa":false,"landing_page_url":"https://doi.org/10.1145/3807503.3819448","pdf_url":null,"source":null,"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 17th ACM International Conference on Bioinformatics, Computational Biology and Health Informatics","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["arxiv","crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://arxiv.org/pdf/2607.19415","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060501824","display_name":"G Y Park","orcid":null},"institutions":[{"id":"https://openalex.org/I200870766","display_name":"Brookhaven National Laboratory","ror":"https://ror.org/02ex6cf31","country_code":"US","type":"facility","lineage":["https://openalex.org/I1330989302","https://openalex.org/I200870766","https://openalex.org/I39565521","https://openalex.org/I4210142672"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gilchan Park","raw_affiliation_strings":["Brookhaven National Laboratory, Upton, NY, USA"],"raw_orcid":"https://orcid.org/0000-0002-0153-6646","affiliations":[{"raw_affiliation_string":"Brookhaven National Laboratory, Upton, NY, USA","institution_ids":["https://openalex.org/I200870766"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068023274","display_name":"Guang Zhao","orcid":"https://orcid.org/0000-0003-0002-5972"},"institutions":[{"id":"https://openalex.org/I200870766","display_name":"Brookhaven National Laboratory","ror":"https://ror.org/02ex6cf31","country_code":"US","type":"facility","lineage":["https://openalex.org/I1330989302","https://openalex.org/I200870766","https://openalex.org/I39565521","https://openalex.org/I4210142672"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Guang Zhao","raw_affiliation_strings":["Brookhaven National Laboratory, Upton, New York, USA"],"raw_orcid":"https://orcid.org/0000-0001-6843-8242","affiliations":[{"raw_affiliation_string":"Brookhaven National Laboratory, Upton, New York, USA","institution_ids":["https://openalex.org/I200870766"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081620315","display_name":"Byung-Jun Yoon","orcid":"https://orcid.org/0000-0001-9328-1101"},"institutions":[{"id":"https://openalex.org/I200870766","display_name":"Brookhaven National Laboratory","ror":"https://ror.org/02ex6cf31","country_code":"US","type":"facility","lineage":["https://openalex.org/I1330989302","https://openalex.org/I200870766","https://openalex.org/I39565521","https://openalex.org/I4210142672"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Byung-Jun Yoon","raw_affiliation_strings":["Brookhaven National Laboratory, Upton, New York, USA"],"raw_orcid":"https://orcid.org/0000-0001-9328-1101","affiliations":[{"raw_affiliation_string":"Brookhaven National Laboratory, Upton, New York, USA","institution_ids":["https://openalex.org/I200870766"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5143544530","display_name":"Shinjae Yoo","orcid":null},"institutions":[{"id":"https://openalex.org/I200870766","display_name":"Brookhaven National Laboratory","ror":"https://ror.org/02ex6cf31","country_code":"US","type":"facility","lineage":["https://openalex.org/I1330989302","https://openalex.org/I200870766","https://openalex.org/I39565521","https://openalex.org/I4210142672"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shinjae Yoo","raw_affiliation_strings":["Brookhaven National Laboratory, Upton, New York, USA"],"raw_orcid":"https://orcid.org/0000-0003-4378-6448","affiliations":[{"raw_affiliation_string":"Brookhaven National Laboratory, Upton, New York, USA","institution_ids":["https://openalex.org/I200870766"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I200870766"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.98774885,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9297999739646912,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9297999739646912,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.010700000450015068,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11190","display_name":"3D Printing in Biomedical Research","score":0.003700000001117587,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/morphology","display_name":"Morphology (biology)","score":0.532800018787384},{"id":"https://openalex.org/keywords/identifier","display_name":"Identifier","score":0.4203999936580658},{"id":"https://openalex.org/keywords/cell-survival","display_name":"Cell survival","score":0.3467999994754791},{"id":"https://openalex.org/keywords/systems-biology","display_name":"Systems biology","score":0.34630000591278076},{"id":"https://openalex.org/keywords/audit","display_name":"Audit","score":0.27959999442100525}],"concepts":[{"id":"https://openalex.org/C499950583","wikidata":"https://www.wikidata.org/wiki/Q183252","display_name":"Morphology (biology)","level":2,"score":0.532800018787384},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4537999927997589},{"id":"https://openalex.org/C154504017","wikidata":"https://www.wikidata.org/wiki/Q853614","display_name":"Identifier","level":2,"score":0.4203999936580658},{"id":"https://openalex.org/C3019137385","wikidata":"https://www.wikidata.org/wiki/Q189159","display_name":"Cell survival","level":3,"score":0.3467999994754791},{"id":"https://openalex.org/C152662350","wikidata":"https://www.wikidata.org/wiki/Q815297","display_name":"Systems biology","level":2,"score":0.34630000591278076},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3366999924182892},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.30799999833106995},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.3043000102043152},{"id":"https://openalex.org/C199521495","wikidata":"https://www.wikidata.org/wiki/Q181487","display_name":"Audit","level":2,"score":0.27959999442100525},{"id":"https://openalex.org/C120577422","wikidata":"https://www.wikidata.org/wiki/Q843558","display_name":"Alternative hypothesis","level":3,"score":0.26840001344680786},{"id":"https://openalex.org/C63479239","wikidata":"https://www.wikidata.org/wiki/Q7353546","display_name":"Robustness (evolution)","level":3,"score":0.2538999915122986},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.25209999084472656}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1145/3807503.3819448","is_oa":false,"landing_page_url":"https://doi.org/10.1145/3807503.3819448","pdf_url":null,"source":null,"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 17th ACM International Conference on Bioinformatics, Computational Biology and Health Informatics","raw_type":"proceedings-article"},{"id":"pmh:oai:arXiv.org:2607.19415","is_oa":true,"landing_page_url":"https://arxiv.org/abs/2607.19415","pdf_url":"https://arxiv.org/pdf/2607.19415","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"}],"best_oa_location":{"id":"pmh:oai:arXiv.org:2607.19415","is_oa":true,"landing_page_url":"https://arxiv.org/abs/2607.19415","pdf_url":"https://arxiv.org/pdf/2607.19415","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},"sustainable_development_goals":[{"score":0.7657009959220886,"id":"https://metadata.un.org/sdg/4","display_name":"Quality Education"}],"awards":[{"id":"https://openalex.org/G1751644051","display_name":null,"funder_award_id":"DE-AC02-06CH11357","funder_id":"https://openalex.org/F4320332359","funder_display_name":"Office of Science"},{"id":"https://openalex.org/G2777053550","display_name":null,"funder_award_id":"AC02-06CH11357","funder_id":"https://openalex.org/F4320306084","funder_display_name":"U.S. Department of Energy"},{"id":"https://openalex.org/G3311144436","display_name":null,"funder_award_id":"DE-AC02-06CH11357","funder_id":"https://openalex.org/F4320337509","funder_display_name":"Biological and Environmental Research"},{"id":"https://openalex.org/G498139845","display_name":null,"funder_award_id":"DE-AC02","funder_id":"https://openalex.org/F4320332359","funder_display_name":"Office of Science"},{"id":"https://openalex.org/G6558272803","display_name":null,"funder_award_id":"DE-AC02","funder_id":"https://openalex.org/F4320306084","funder_display_name":"U.S. Department of Energy"},{"id":"https://openalex.org/G6848031779","display_name":null,"funder_award_id":"06CH11357","funder_id":"https://openalex.org/F4320306084","funder_display_name":"U.S. Department of Energy"},{"id":"https://openalex.org/G6918803902","display_name":null,"funder_award_id":"06CH11357","funder_id":"https://openalex.org/F4320332359","funder_display_name":"Office of Science"},{"id":"https://openalex.org/G8143874970","display_name":null,"funder_award_id":"AC02-06CH11357","funder_id":"https://openalex.org/F4320332359","funder_display_name":"Office of Science"},{"id":"https://openalex.org/G969889393","display_name":null,"funder_award_id":"DE-AC02-","funder_id":"https://openalex.org/F4320306084","funder_display_name":"U.S. Department of Energy"}],"funders":[{"id":"https://openalex.org/F4320306084","display_name":"U.S. Department of Energy","ror":"https://ror.org/01bj3aw27"},{"id":"https://openalex.org/F4320332359","display_name":"Office of Science","ror":"https://ror.org/00mmn6b08"},{"id":"https://openalex.org/F4320337509","display_name":"Biological and Environmental Research","ror":"https://ror.org/0114b2m14"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7170496102.pdf","grobid_xml":"https://content.openalex.org/works/W7170496102.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":[],"abstract_inverted_index":{"High-content":[0],"morphological":[1],"profiling":[2],"(Cell":[3],"Painting)":[4],"yields":[5],"sensitive,":[6],"high-dimensional":[7],"signatures":[8],"of":[9],"cellular":[10],"state,":[11],"but":[12],"translating":[13],"longitudinal":[14],"morphology":[15],"trajectories":[16],"into":[17,39],"interpretable":[18],"biology":[19],"remains":[20],"difficult\u2014especially":[21],"for":[22],"weak,":[23],"chronic":[24],"perturbations":[25],"such":[26],"as":[27],"low-dose-rate":[28],"ionizing":[29],"radiation.":[30],"Large":[31],"language":[32],"models":[33],"(LLMs)":[34],"can":[35],"synthesize":[36],"heterogeneous":[37],"evidence":[38],"narratives,":[40],"yet":[41],"scientific":[42],"use":[43],"requires":[44],"quantitative":[45],"auditing:":[46],"fluent":[47],"outputs":[48],"may":[49],"be":[50],"ungrounded":[51],"or":[52],"inconsistent":[53],"with":[54],"measured":[55],"morphology.":[56]},"counts_by_year":[],"updated_date":"2026-07-30T17:31:21.811387","created_date":"2026-07-25T00:00:00"}