{"id":"https://openalex.org/W4387346466","doi":"https://doi.org/10.1145/3584371.3613059","title":"Computational Methods to Determine Genetic Factors in Nicotine Dependency","display_name":"Computational Methods to Determine Genetic Factors in Nicotine Dependency","publication_year":2023,"publication_date":"2023-09-03","ids":{"openalex":"https://openalex.org/W4387346466","doi":"https://doi.org/10.1145/3584371.3613059"},"language":"en","primary_location":{"id":"doi:10.1145/3584371.3613059","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1145/3584371.3613059","pdf_url":"https://dl.acm.org/doi/pdf/10.1145/3584371.3613059","source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 14th ACM International Conference on Bioinformatics, Computational Biology, and Health Informatics","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://dl.acm.org/doi/pdf/10.1145/3584371.3613059","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068110198","display_name":"Kevin Yang","orcid":"https://orcid.org/0009-0005-6370-4931"},"institutions":[{"id":"https://openalex.org/I4210130191","display_name":"Cranbrook Institute of Science","ror":"https://ror.org/02ec2g004","country_code":"US","type":"archive","lineage":["https://openalex.org/I4210130191"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Kevin Kaizhe Yang","raw_affiliation_strings":["Cranbrook Kingswood School, Rochester Hills, Michigan, USA"],"raw_orcid":"https://orcid.org/0009-0005-6370-4931","affiliations":[{"raw_affiliation_string":"Cranbrook Kingswood School, Rochester Hills, Michigan, USA","institution_ids":["https://openalex.org/I4210130191"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5044404674","display_name":"Julian A. Stanley","orcid":"https://orcid.org/0000-0002-9193-3791"},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Julian Stanley","raw_affiliation_strings":["Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA"],"raw_orcid":"https://orcid.org/0000-0002-9193-3791","affiliations":[{"raw_affiliation_string":"Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA","institution_ids":["https://openalex.org/I63966007"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5068110198"],"corresponding_institution_ids":["https://openalex.org/I4210130191"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.21688104,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"1"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10060","display_name":"Smoking Behavior and Cessation","score":0.9934999942779541,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10060","display_name":"Smoking Behavior and Cessation","score":0.9934999942779541,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11818","display_name":"Nicotinic Acetylcholine Receptors Study","score":0.9854999780654907,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9070000052452087,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nicotine","display_name":"Nicotine","score":0.842842161655426},{"id":"https://openalex.org/keywords/nicotine-dependence","display_name":"Nicotine dependence","score":0.7130535840988159},{"id":"https://openalex.org/keywords/dependency","display_name":"Dependency (UML)","score":0.637022852897644},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.6167200803756714},{"id":"https://openalex.org/keywords/smoking-cessation","display_name":"Smoking cessation","score":0.5375046730041504},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.43913161754608154},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.40046724677085876},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.3754400908946991},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.35811737179756165},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.322908490896225},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.24209082126617432},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.22327730059623718},{"id":"https://openalex.org/keywords/psychiatry","display_name":"Psychiatry","score":0.19168725609779358}],"concepts":[{"id":"https://openalex.org/C2779547902","wikidata":"https://www.wikidata.org/wiki/Q28086552","display_name":"Nicotine","level":2,"score":0.842842161655426},{"id":"https://openalex.org/C2778647338","wikidata":"https://www.wikidata.org/wiki/Q18553444","display_name":"Nicotine dependence","level":3,"score":0.7130535840988159},{"id":"https://openalex.org/C19768560","wikidata":"https://www.wikidata.org/wiki/Q320727","display_name":"Dependency (UML)","level":2,"score":0.637022852897644},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.6167200803756714},{"id":"https://openalex.org/C2777843972","wikidata":"https://www.wikidata.org/wiki/Q2462253","display_name":"Smoking cessation","level":2,"score":0.5375046730041504},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.43913161754608154},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.40046724677085876},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3754400908946991},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.35811737179756165},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.322908490896225},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.24209082126617432},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.22327730059623718},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.19168725609779358},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1145/3584371.3613059","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1145/3584371.3613059","pdf_url":"https://dl.acm.org/doi/pdf/10.1145/3584371.3613059","source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 14th ACM International Conference on Bioinformatics, Computational Biology, and Health Informatics","raw_type":"proceedings-article"}],"best_oa_location":{"id":"doi:10.1145/3584371.3613059","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1145/3584371.3613059","pdf_url":"https://dl.acm.org/doi/pdf/10.1145/3584371.3613059","source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 14th ACM International Conference on Bioinformatics, Computational Biology, and Health Informatics","raw_type":"proceedings-article"},"sustainable_development_goals":[{"score":0.8700000047683716,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4387346466.pdf","grobid_xml":"https://content.openalex.org/works/W4387346466.grobid-xml"},"referenced_works_count":2,"referenced_works":["https://openalex.org/W1982729071","https://openalex.org/W2137599927"],"related_works":["https://openalex.org/W2022981145","https://openalex.org/W2033670595","https://openalex.org/W2332404483","https://openalex.org/W1996479013","https://openalex.org/W1970486150","https://openalex.org/W2047516780","https://openalex.org/W2410296250","https://openalex.org/W3094854700","https://openalex.org/W2349548013","https://openalex.org/W2990023056"],"abstract_inverted_index":{"If":[0],"nicotine":[1,36],"dependence":[2],"is":[3,15],"highly":[4],"genetic,":[5],"then":[6],"we":[7],"should":[8],"be":[9],"able":[10],"to":[11],"predict":[12],"whether":[13],"someone":[14],"a":[16],"smoker":[17],"based":[18],"on":[19],"their":[20],"gene":[21],"expression":[22],"alone.":[23],"A":[24],"better":[25],"understanding":[26],"of":[27,31,43,50],"the":[28,41,48],"genetic":[29],"basis":[30],"smoking":[32,51],"status,":[33],"and":[34,47],"thereby":[35],"dependence,":[37],"will":[38],"aid":[39],"in":[40],"identification":[42],"smoking-associated":[44],"risk":[45],"factors,":[46],"development":[49],"cessation":[52],"drugs.":[53]},"counts_by_year":[],"updated_date":"2025-12-23T23:11:35.936235","created_date":"2025-10-10T00:00:00"}