{"id":"https://openalex.org/W4387212741","doi":"https://doi.org/10.1145/3570361.3592499","title":"TherapyPal: Towards a Privacy-Preserving Companion Diagnostic Tool based on Digital Symptomatic Phenotyping","display_name":"TherapyPal: Towards a Privacy-Preserving Companion Diagnostic Tool based on Digital Symptomatic Phenotyping","publication_year":2023,"publication_date":"2023-09-30","ids":{"openalex":"https://openalex.org/W4387212741","doi":"https://doi.org/10.1145/3570361.3592499"},"language":"en","primary_location":{"id":"doi:10.1145/3570361.3592499","is_oa":false,"landing_page_url":"https://doi.org/10.1145/3570361.3592499","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 29th Annual International Conference on Mobile Computing and Networking","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055511404","display_name":"Huining Li","orcid":"https://orcid.org/0000-0003-3865-3587"},"institutions":[{"id":"https://openalex.org/I63190737","display_name":"University at Buffalo, State University of New York","ror":"https://ror.org/01y64my43","country_code":"US","type":"education","lineage":["https://openalex.org/I63190737"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Huining Li","raw_affiliation_strings":["University at Buffalo, SUNY, Buffalo, USA"],"affiliations":[{"raw_affiliation_string":"University at Buffalo, SUNY, Buffalo, USA","institution_ids":["https://openalex.org/I63190737"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076677679","display_name":"Xiaoye Qian","orcid":"https://orcid.org/0000-0001-7543-4696"},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiaoye Qian","raw_affiliation_strings":["Case Western Reserve University, Cleveland, USA"],"affiliations":[{"raw_affiliation_string":"Case Western Reserve University, Cleveland, USA","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101883619","display_name":"Ruokai Ma","orcid":"https://orcid.org/0009-0003-8420-9046"},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ruokai Ma","raw_affiliation_strings":["Zhejiang University, Hangzhou, China"],"affiliations":[{"raw_affiliation_string":"Zhejiang University, Hangzhou, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027249863","display_name":"Chenhan Xu","orcid":"https://orcid.org/0000-0002-1395-4570"},"institutions":[{"id":"https://openalex.org/I63190737","display_name":"University at Buffalo, State University of New York","ror":"https://ror.org/01y64my43","country_code":"US","type":"education","lineage":["https://openalex.org/I63190737"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chenhan Xu","raw_affiliation_strings":["University at Buffalo, SUNY, Buffalo, United States"],"affiliations":[{"raw_affiliation_string":"University at Buffalo, SUNY, Buffalo, United States","institution_ids":["https://openalex.org/I63190737"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016863481","display_name":"Zhengxiong Li","orcid":"https://orcid.org/0000-0003-1880-5096"},"institutions":[{"id":"https://openalex.org/I921990950","display_name":"University of Colorado Denver","ror":"https://ror.org/02hh7en24","country_code":"US","type":"education","lineage":["https://openalex.org/I921990950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhengxiong Li","raw_affiliation_strings":["University of Colorado Denver, Denver, United States"],"affiliations":[{"raw_affiliation_string":"University of Colorado Denver, Denver, United States","institution_ids":["https://openalex.org/I921990950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100417601","display_name":"Dongmei Li","orcid":"https://orcid.org/0000-0001-9140-2483"},"institutions":[{"id":"https://openalex.org/I28792581","display_name":"University of Rochester Medical Center","ror":"https://ror.org/00trqv719","country_code":"US","type":"funder","lineage":["https://openalex.org/I28792581","https://openalex.org/I5388228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dongmei Li","raw_affiliation_strings":["University of Rochester Medical Center, Rochester, USA"],"affiliations":[{"raw_affiliation_string":"University of Rochester Medical Center, Rochester, USA","institution_ids":["https://openalex.org/I28792581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078406349","display_name":"Feng Lin","orcid":"https://orcid.org/0000-0001-5240-5200"},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Feng Lin","raw_affiliation_strings":["Zhejiang University, Hangzhou, China"],"affiliations":[{"raw_affiliation_string":"Zhejiang University, Hangzhou, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020169895","display_name":"Ming-Chun Huang","orcid":"https://orcid.org/0000-0002-2269-4694"},"institutions":[{"id":"https://openalex.org/I4210159968","display_name":"Duke Kunshan University","ror":"https://ror.org/04sr5ys16","country_code":"CN","type":"education","lineage":["https://openalex.org/I170897317","https://openalex.org/I37461747","https://openalex.org/I4210159968"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ming-Chun Huang","raw_affiliation_strings":["Duke Kunshan University, Suzhou, China"],"affiliations":[{"raw_affiliation_string":"Duke Kunshan University, Suzhou, China","institution_ids":["https://openalex.org/I4210159968"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035679293","display_name":"Wenyao Xu","orcid":"https://orcid.org/0000-0001-6444-9411"},"institutions":[{"id":"https://openalex.org/I63190737","display_name":"University at Buffalo, State University of New York","ror":"https://ror.org/01y64my43","country_code":"US","type":"education","lineage":["https://openalex.org/I63190737"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wenyao Xu","raw_affiliation_strings":["University at Buffalo, SUNY, Buffalo, United States"],"affiliations":[{"raw_affiliation_string":"University at Buffalo, SUNY, Buffalo, United States","institution_ids":["https://openalex.org/I63190737"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5055511404"],"corresponding_institution_ids":["https://openalex.org/I63190737"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.12880151,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"15"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11407","display_name":"Innovative Microfluidic and Catalytic Techniques Innovation","score":0.9587000012397766,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11407","display_name":"Innovative Microfluidic and Catalytic Techniques Innovation","score":0.9587000012397766,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7490648031234741},{"id":"https://openalex.org/keywords/reliability","display_name":"Reliability (semiconductor)","score":0.5461928844451904},{"id":"https://openalex.org/keywords/precision-medicine","display_name":"Precision medicine","score":0.47701406478881836},{"id":"https://openalex.org/keywords/deep-learning","display_name":"Deep learning","score":0.46593183279037476},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4451260268688202},{"id":"https://openalex.org/keywords/cloud-computing","display_name":"Cloud computing","score":0.4404659867286682},{"id":"https://openalex.org/keywords/mobile-device","display_name":"Mobile device","score":0.43683576583862305},{"id":"https://openalex.org/keywords/hash-function","display_name":"Hash function","score":0.4203723073005676},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.4163113236427307},{"id":"https://openalex.org/keywords/computer-security","display_name":"Computer security","score":0.34298190474510193},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.18612712621688843},{"id":"https://openalex.org/keywords/world-wide-web","display_name":"World Wide Web","score":0.1623530387878418}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7490648031234741},{"id":"https://openalex.org/C43214815","wikidata":"https://www.wikidata.org/wiki/Q7310987","display_name":"Reliability (semiconductor)","level":3,"score":0.5461928844451904},{"id":"https://openalex.org/C163763905","wikidata":"https://www.wikidata.org/wiki/Q17075943","display_name":"Precision medicine","level":2,"score":0.47701406478881836},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.46593183279037476},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4451260268688202},{"id":"https://openalex.org/C79974875","wikidata":"https://www.wikidata.org/wiki/Q483639","display_name":"Cloud computing","level":2,"score":0.4404659867286682},{"id":"https://openalex.org/C186967261","wikidata":"https://www.wikidata.org/wiki/Q5082128","display_name":"Mobile device","level":2,"score":0.43683576583862305},{"id":"https://openalex.org/C99138194","wikidata":"https://www.wikidata.org/wiki/Q183427","display_name":"Hash function","level":2,"score":0.4203723073005676},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.4163113236427307},{"id":"https://openalex.org/C38652104","wikidata":"https://www.wikidata.org/wiki/Q3510521","display_name":"Computer security","level":1,"score":0.34298190474510193},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.18612712621688843},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.1623530387878418},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C163258240","wikidata":"https://www.wikidata.org/wiki/Q25342","display_name":"Power (physics)","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1145/3570361.3592499","is_oa":false,"landing_page_url":"https://doi.org/10.1145/3570361.3592499","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 29th Annual International Conference on Mobile Computing and Networking","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":51,"referenced_works":["https://openalex.org/W1502916507","https://openalex.org/W1754359741","https://openalex.org/W1755292678","https://openalex.org/W1983293608","https://openalex.org/W1987040325","https://openalex.org/W1987971958","https://openalex.org/W2017475793","https://openalex.org/W2066438775","https://openalex.org/W2072566913","https://openalex.org/W2076281963","https://openalex.org/W2088359773","https://openalex.org/W2102605133","https://openalex.org/W2106983119","https://openalex.org/W2108901766","https://openalex.org/W2124603119","https://openalex.org/W2140978740","https://openalex.org/W2149485684","https://openalex.org/W2182933069","https://openalex.org/W2403155415","https://openalex.org/W2415630729","https://openalex.org/W2435473771","https://openalex.org/W2502518763","https://openalex.org/W2514281243","https://openalex.org/W2567921357","https://openalex.org/W2724359148","https://openalex.org/W2768347741","https://openalex.org/W2808282156","https://openalex.org/W2884985453","https://openalex.org/W2898291644","https://openalex.org/W2918079264","https://openalex.org/W2939413249","https://openalex.org/W2943917351","https://openalex.org/W2954996726","https://openalex.org/W2964158883","https://openalex.org/W2973044443","https://openalex.org/W3004844226","https://openalex.org/W3033231068","https://openalex.org/W3137844657","https://openalex.org/W3139752690","https://openalex.org/W3158394771","https://openalex.org/W3207216021","https://openalex.org/W3207618705","https://openalex.org/W4303685239","https://openalex.org/W6629956336","https://openalex.org/W6642268209","https://openalex.org/W6686001067","https://openalex.org/W6696891034","https://openalex.org/W6713414828","https://openalex.org/W6774491127","https://openalex.org/W7015229541","https://openalex.org/W7075632487"],"related_works":["https://openalex.org/W4244478748","https://openalex.org/W4223488648","https://openalex.org/W2134969820","https://openalex.org/W2251605416","https://openalex.org/W2560439919","https://openalex.org/W4389340727","https://openalex.org/W3150465815","https://openalex.org/W1997222214","https://openalex.org/W2802581102","https://openalex.org/W4205786897"],"abstract_inverted_index":{"As":[0],"the":[1,51,63,137,145,189],"demand":[2],"for":[3,18,139,182],"precision":[4],"medicine":[5,20,85,127,171],"rapidly":[6],"grows,":[7],"companion":[8,29,70,201],"diagnostics":[9,30,202],"is":[10,103],"proposed":[11],"to":[12,53,115,131,195],"monitor":[13],"and":[14,42,177,191],"evaluate":[15,144],"therapeutic":[16],"effects":[17],"adjusting":[19],"plans":[21],"in":[22,45,136],"time.":[23],"Although":[24],"a":[25,46,68,83,111,132,149,199],"set":[26],"of":[27,58,193],"clinical":[28,150],"tools":[31],"(e.g.,":[32],"polymerase":[33],"chain":[34],"reaction)":[35],"have":[36],"been":[37],"investigated,":[38],"they":[39],"are":[40,129],"expensive":[41],"only":[43],"accessible":[44],"lab":[47],"environment,":[48],"which":[49,187],"hinders":[50],"promotion":[52],"broader":[54],"patients.":[55],"In":[56,77],"light":[57],"this":[59,78],"situation,":[60],"we":[61,80,109,147],"take":[62],"first":[64,104],"steps":[65],"towards":[66],"developing":[67],"real-world":[69,200],"diagnostic":[71],"tool":[72],"by":[73,89],"leveraging":[74],"mobile":[75],"technology.":[76],"paper,":[79],"present":[81],"TherapyPal,":[82],"privacy-preserving":[84],"effectiveness":[86,141,172],"computational":[87],"framework":[88],"harnessing":[90],"semantic":[91],"hashing-based":[92],"digital":[93],"symptomatic":[94,118,123],"phenotyping.":[95],"Specifically,":[96],"sensor":[97],"data":[98],"captured":[99],"from":[100],"daily-life":[101],"activities":[102],"transformed":[105],"into":[106],"spectrograms.":[107],"Then,":[108],"develop":[110],"hashing":[112],"learning":[113,134],"network":[114,135],"extract":[116],"privacy-masked":[117,180],"phenotypes":[119],"on":[120],"smartphones.":[121],"Afterward,":[122],"hashes":[124],"at":[125],"different":[126],"states":[128],"fed":[130],"contrastive":[133],"cloud":[138],"treatment":[140],"detection.":[142],"To":[143],"performance,":[146],"conduct":[148],"study":[151],"among":[152,175],"65":[153],"Parkinson's":[154],"disease":[155],"(PD)":[156],"patients":[157,176],"under":[158],"dopaminergic":[159],"drug":[160],"treatment.":[161],"The":[162],"results":[163],"show":[164],"that":[165],"TherapyPal":[166,194],"can":[167],"achieve":[168],"around":[169],"84.1%":[170],"detection":[173],"accuracy":[174],"above":[178],"0.925":[179],"scores":[181],"protecting":[183],"each":[184],"private":[185],"attribute,":[186],"validates":[188],"reliability":[190],"security":[192],"be":[196],"used":[197],"as":[198],"tool.":[203]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}