{"id":"https://openalex.org/W4285728566","doi":"https://doi.org/10.1145/3548777","title":"BioLumin: An Immersive Mixed Reality Experience for Interactive Microscopic Visualization and Biomedical Research Annotation","display_name":"BioLumin: An Immersive Mixed Reality Experience for Interactive Microscopic Visualization and Biomedical Research Annotation","publication_year":2022,"publication_date":"2022-07-18","ids":{"openalex":"https://openalex.org/W4285728566","doi":"https://doi.org/10.1145/3548777"},"language":"en","primary_location":{"id":"doi:10.1145/3548777","is_oa":true,"landing_page_url":"https://doi.org/10.1145/3548777","pdf_url":"https://dl.acm.org/doi/pdf/10.1145/3548777","source":{"id":"https://openalex.org/S4210174653","display_name":"ACM Transactions on Computing for Healthcare","issn_l":"2637-8051","issn":["2637-8051","2691-1957"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319798","host_organization_name":"Association for Computing Machinery","host_organization_lineage":["https://openalex.org/P4310319798"],"host_organization_lineage_names":["Association for Computing Machinery"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ACM Transactions on Computing for Healthcare","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://dl.acm.org/doi/pdf/10.1145/3548777","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030186036","display_name":"Aviv Elor","orcid":"https://orcid.org/0000-0001-5356-3948"},"institutions":[{"id":"https://openalex.org/I185103710","display_name":"University of California, Santa Cruz","ror":"https://ror.org/03s65by71","country_code":"US","type":"education","lineage":["https://openalex.org/I185103710"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Aviv Elor","raw_affiliation_strings":["University of California, Santa Cruz, CA, USA"],"affiliations":[{"raw_affiliation_string":"University of California, Santa Cruz, CA, USA","institution_ids":["https://openalex.org/I185103710"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075713144","display_name":"Steve Whittaker","orcid":"https://orcid.org/0000-0003-3893-2551"},"institutions":[{"id":"https://openalex.org/I185103710","display_name":"University of California, Santa Cruz","ror":"https://ror.org/03s65by71","country_code":"US","type":"education","lineage":["https://openalex.org/I185103710"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steve Whittaker","raw_affiliation_strings":["University of California, Santa Cruz, CA, USA"],"affiliations":[{"raw_affiliation_string":"University of California, Santa Cruz, CA, USA","institution_ids":["https://openalex.org/I185103710"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103181909","display_name":"Sri Kurniawan","orcid":"https://orcid.org/0000-0002-2974-7963"},"institutions":[{"id":"https://openalex.org/I185103710","display_name":"University of California, Santa Cruz","ror":"https://ror.org/03s65by71","country_code":"US","type":"education","lineage":["https://openalex.org/I185103710"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sri Kurniawan","raw_affiliation_strings":["University of California, Santa Cruz, CA, USA"],"affiliations":[{"raw_affiliation_string":"University of California, Santa Cruz, CA, USA","institution_ids":["https://openalex.org/I185103710"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059243759","display_name":"Sam Michael","orcid":"https://orcid.org/0000-0002-1070-6563"},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210148682","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210148682"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sam Michael","raw_affiliation_strings":["The National Institutes of Health, National Center for Advancing Translational Sciences, Bethesda MD, USA"],"affiliations":[{"raw_affiliation_string":"The National Institutes of Health, National Center for Advancing Translational Sciences, Bethesda MD, USA","institution_ids":["https://openalex.org/I4210148682","https://openalex.org/I1299303238"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5030186036"],"corresponding_institution_ids":["https://openalex.org/I185103710"],"apc_list":null,"apc_paid":null,"fwci":1.3216,"has_fulltext":true,"cited_by_count":6,"citation_normalized_percentile":{"value":0.84487904,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"3","issue":"4","first_page":"1","last_page":"28"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9975000023841858,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9975000023841858,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10648","display_name":"Virtual Reality Applications and Impacts","score":0.9835000038146973,"subfield":{"id":"https://openalex.org/subfields/1709","display_name":"Human-Computer Interaction"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10799","display_name":"Data Visualization and Analytics","score":0.9771999716758728,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7582853436470032},{"id":"https://openalex.org/keywords/annotation","display_name":"Annotation","score":0.69178307056427},{"id":"https://openalex.org/keywords/usability","display_name":"Usability","score":0.6276935935020447},{"id":"https://openalex.org/keywords/domain","display_name":"Domain (mathematical analysis)","score":0.6167956590652466},{"id":"https://openalex.org/keywords/session","display_name":"Session (web analytics)","score":0.5740993618965149},{"id":"https://openalex.org/keywords/human\u2013computer-interaction","display_name":"Human\u2013computer interaction","score":0.5713756680488586},{"id":"https://openalex.org/keywords/pipeline","display_name":"Pipeline (software)","score":0.5687131285667419},{"id":"https://openalex.org/keywords/visualization","display_name":"Visualization","score":0.5610701441764832},{"id":"https://openalex.org/keywords/mixed-reality","display_name":"Mixed reality","score":0.53626948595047},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.4541371464729309},{"id":"https://openalex.org/keywords/quality","display_name":"Quality (philosophy)","score":0.4199204444885254},{"id":"https://openalex.org/keywords/virtual-reality","display_name":"Virtual reality","score":0.3895410895347595},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.31418514251708984},{"id":"https://openalex.org/keywords/world-wide-web","display_name":"World Wide Web","score":0.16891193389892578}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7582853436470032},{"id":"https://openalex.org/C2776321320","wikidata":"https://www.wikidata.org/wiki/Q857525","display_name":"Annotation","level":2,"score":0.69178307056427},{"id":"https://openalex.org/C170130773","wikidata":"https://www.wikidata.org/wiki/Q216378","display_name":"Usability","level":2,"score":0.6276935935020447},{"id":"https://openalex.org/C36503486","wikidata":"https://www.wikidata.org/wiki/Q11235244","display_name":"Domain (mathematical analysis)","level":2,"score":0.6167956590652466},{"id":"https://openalex.org/C2779182362","wikidata":"https://www.wikidata.org/wiki/Q17126187","display_name":"Session (web analytics)","level":2,"score":0.5740993618965149},{"id":"https://openalex.org/C107457646","wikidata":"https://www.wikidata.org/wiki/Q207434","display_name":"Human\u2013computer interaction","level":1,"score":0.5713756680488586},{"id":"https://openalex.org/C43521106","wikidata":"https://www.wikidata.org/wiki/Q2165493","display_name":"Pipeline (software)","level":2,"score":0.5687131285667419},{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.5610701441764832},{"id":"https://openalex.org/C206776904","wikidata":"https://www.wikidata.org/wiki/Q1758389","display_name":"Mixed reality","level":3,"score":0.53626948595047},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.4541371464729309},{"id":"https://openalex.org/C2779530757","wikidata":"https://www.wikidata.org/wiki/Q1207505","display_name":"Quality (philosophy)","level":2,"score":0.4199204444885254},{"id":"https://openalex.org/C194969405","wikidata":"https://www.wikidata.org/wiki/Q170519","display_name":"Virtual reality","level":2,"score":0.3895410895347595},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.31418514251708984},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.16891193389892578},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1145/3548777","is_oa":true,"landing_page_url":"https://doi.org/10.1145/3548777","pdf_url":"https://dl.acm.org/doi/pdf/10.1145/3548777","source":{"id":"https://openalex.org/S4210174653","display_name":"ACM Transactions on Computing for Healthcare","issn_l":"2637-8051","issn":["2637-8051","2691-1957"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319798","host_organization_name":"Association for Computing Machinery","host_organization_lineage":["https://openalex.org/P4310319798"],"host_organization_lineage_names":["Association for Computing Machinery"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ACM Transactions on Computing for Healthcare","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1145/3548777","is_oa":true,"landing_page_url":"https://doi.org/10.1145/3548777","pdf_url":"https://dl.acm.org/doi/pdf/10.1145/3548777","source":{"id":"https://openalex.org/S4210174653","display_name":"ACM Transactions on Computing for Healthcare","issn_l":"2637-8051","issn":["2637-8051","2691-1957"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319798","host_organization_name":"Association for Computing Machinery","host_organization_lineage":["https://openalex.org/P4310319798"],"host_organization_lineage_names":["Association for Computing Machinery"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ACM Transactions on Computing for Healthcare","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1828171283","display_name":null,"funder_award_id":"0000000","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G5788812909","display_name":null,"funder_award_id":"0000000","funder_id":"https://openalex.org/F4320309018","funder_display_name":"University of California, Santa Cruz"},{"id":"https://openalex.org/G8198795195","display_name":null,"funder_award_id":"00001","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320309018","display_name":"University of California, Santa Cruz","ror":"https://ror.org/03s65by71"},{"id":"https://openalex.org/F4320315033","display_name":"Banatao Institute","ror":null},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337472","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4285728566.pdf","grobid_xml":"https://content.openalex.org/works/W4285728566.grobid-xml"},"referenced_works_count":59,"referenced_works":["https://openalex.org/W19399978","https://openalex.org/W1602554638","https://openalex.org/W1888870946","https://openalex.org/W1961379460","https://openalex.org/W1976676790","https://openalex.org/W1984695931","https://openalex.org/W1989883122","https://openalex.org/W2004298112","https://openalex.org/W2026096417","https://openalex.org/W2028279608","https://openalex.org/W2032191478","https://openalex.org/W2032991527","https://openalex.org/W2036226049","https://openalex.org/W2047209146","https://openalex.org/W2048132727","https://openalex.org/W2052377591","https://openalex.org/W2066295131","https://openalex.org/W2066417291","https://openalex.org/W2073893432","https://openalex.org/W2080993455","https://openalex.org/W2086084081","https://openalex.org/W2100082357","https://openalex.org/W2101798695","https://openalex.org/W2112946624","https://openalex.org/W2114058809","https://openalex.org/W2114853176","https://openalex.org/W2116958202","https://openalex.org/W2137184377","https://openalex.org/W2151103962","https://openalex.org/W2153490111","https://openalex.org/W2154915448","https://openalex.org/W2159065226","https://openalex.org/W2171057921","https://openalex.org/W2178182204","https://openalex.org/W2180710631","https://openalex.org/W2228329932","https://openalex.org/W2253179553","https://openalex.org/W2264375300","https://openalex.org/W2294623589","https://openalex.org/W2297024106","https://openalex.org/W2415539183","https://openalex.org/W2502464994","https://openalex.org/W2518340594","https://openalex.org/W2592929672","https://openalex.org/W2607941059","https://openalex.org/W2734372467","https://openalex.org/W2736982640","https://openalex.org/W2738012414","https://openalex.org/W2768930763","https://openalex.org/W2770761158","https://openalex.org/W2801284919","https://openalex.org/W2810109552","https://openalex.org/W2883890990","https://openalex.org/W2913111015","https://openalex.org/W2951403328","https://openalex.org/W3001612893","https://openalex.org/W3041750665","https://openalex.org/W3105398898","https://openalex.org/W6600808634"],"related_works":["https://openalex.org/W1256197635","https://openalex.org/W4240558103","https://openalex.org/W4367662598","https://openalex.org/W2157759147","https://openalex.org/W3116660854","https://openalex.org/W3115771437","https://openalex.org/W1802061832","https://openalex.org/W3037587100","https://openalex.org/W3086523520","https://openalex.org/W2536828439"],"abstract_inverted_index":{"Many":[0],"recent":[1],"breakthroughs":[2],"in":[3,75,147,184],"medical":[4,110,185],"diagnostics":[5],"and":[6,40,62,118,138,161,186],"drug":[7],"discovery":[8],"arise":[9],"from":[10],"deploying":[11],"machine":[12],"learning":[13],"algorithms":[14],"to":[15,23,52,56,81,99],"large-scale":[16],"data":[17,111],"sets.":[18],"However,":[19],"a":[20,43,79,96,103,127,148,170],"significant":[21],"obstacle":[22],"such":[24,102],"approaches":[25],"is":[26],"that":[27,49,154,162],"they":[28],"depend":[29],"on":[30],"high-quality":[31,166],"annotations":[32,168],"generated":[33],"by":[34,112],"domain":[35,71,133],"experts.":[36],"This":[37],"study":[38],"develops":[39],"evaluates":[41],"BioLumin,":[42,121],"novel":[44],"immersive":[45],"mixed":[46,89,156],"reality":[47,90,157],"environment":[48],"enables":[50],"users":[51,142],"virtually":[53],"shrink":[54],"down":[55],"the":[57,76,93,116,155],"microscopic":[58],"level":[59],"for":[60,88,179],"navigation":[61],"annotation":[63,107,145],"of":[64,78,85,95,108,120],"3D":[65,167],"reconstructed":[66],"images.":[67],"We":[68],"discuss":[69,176],"how":[70],"experts":[72,134],"were":[73],"consulted":[74],"specification":[77],"pipeline":[80],"enable":[82],"automatic":[83],"reconstruction":[84],"biological":[86],"models":[87],"environments,":[91],"driving":[92],"design":[94,177],"3DUI":[97],"system":[98,104,158],"explore":[100],"whether":[101],"allows":[105],"accurate":[106],"complex":[109],"non-experts.":[113],"To":[114],"examine":[115],"usability":[117],"feasibility":[119],"we":[122,175],"evaluated":[123],"our":[124],"prototype":[125],"through":[126],"multi-stage":[128],"mixed-method":[129],"approach.":[130],"First,":[131],"three":[132],"offered":[135],"expert":[136],"reviews,":[137],"subsequently,":[139],"nineteen":[140],"non-expert":[141],"performed":[143],"representative":[144],"tasks":[146],"controlled":[149],"setting.":[150],"The":[151],"results":[152],"indicated":[153],"was":[159],"learnable":[160],"non-experts":[163],"could":[164],"generate":[165],"after":[169],"short":[171],"training":[172],"session.":[173],"Lastly,":[174],"considerations":[178],"future":[180],"tools":[181],"like":[182],"BioLumin":[183],"more":[187],"general":[188],"scientific":[189],"contexts.":[190]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3}],"updated_date":"2026-03-16T09:10:04.655348","created_date":"2025-10-10T00:00:00"}