{"id":"https://openalex.org/W3185057758","doi":"https://doi.org/10.1145/3460238.3460263","title":"Review of Role of Epigenetics in Cancer Research","display_name":"Review of Role of Epigenetics in Cancer Research","publication_year":2021,"publication_date":"2021-03-17","ids":{"openalex":"https://openalex.org/W3185057758","doi":"https://doi.org/10.1145/3460238.3460263","mag":"3185057758"},"language":"en","primary_location":{"id":"doi:10.1145/3460238.3460263","is_oa":false,"landing_page_url":"https://doi.org/10.1145/3460238.3460263","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 11th International Conference on Biomedical Engineering and Technology","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088974335","display_name":"Xinyue Zhao","orcid":"https://orcid.org/0000-0002-1051-2216"},"institutions":[{"id":"https://openalex.org/I258800397","display_name":"New York University Shanghai","ror":"https://ror.org/02vpsdb40","country_code":"CN","type":"education","lineage":["https://openalex.org/I258800397","https://openalex.org/I57206974"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xinyue Zhao","raw_affiliation_strings":["New York University Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York University Shanghai, China","institution_ids":["https://openalex.org/I258800397"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5088974335"],"corresponding_institution_ids":["https://openalex.org/I258800397"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.13248971,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"164","last_page":"167"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9944000244140625,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.9934999942779541,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/epigenetics","display_name":"Epigenetics","score":0.8459174633026123},{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.6530581712722778},{"id":"https://openalex.org/keywords/histone","display_name":"Histone","score":0.6466085910797119},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.579074501991272},{"id":"https://openalex.org/keywords/mechanism","display_name":"Mechanism (biology)","score":0.5419772863388062},{"id":"https://openalex.org/keywords/cancer-epigenetics","display_name":"Cancer epigenetics","score":0.5014262199401855},{"id":"https://openalex.org/keywords/rna","display_name":"RNA","score":0.4980795383453369},{"id":"https://openalex.org/keywords/dna","display_name":"DNA","score":0.48412904143333435},{"id":"https://openalex.org/keywords/colorectal-cancer","display_name":"Colorectal cancer","score":0.4727141559123993},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.45410358905792236},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.43377578258514404},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.37965530157089233},{"id":"https://openalex.org/keywords/cancer-research","display_name":"Cancer research","score":0.35337352752685547},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.31454548239707947},{"id":"https://openalex.org/keywords/histone-methyltransferase","display_name":"Histone methyltransferase","score":0.13684117794036865},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.13366907835006714},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.1123407781124115}],"concepts":[{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.8459174633026123},{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.6530581712722778},{"id":"https://openalex.org/C64927066","wikidata":"https://www.wikidata.org/wiki/Q36293","display_name":"Histone","level":3,"score":0.6466085910797119},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.579074501991272},{"id":"https://openalex.org/C89611455","wikidata":"https://www.wikidata.org/wiki/Q6804646","display_name":"Mechanism (biology)","level":2,"score":0.5419772863388062},{"id":"https://openalex.org/C114691636","wikidata":"https://www.wikidata.org/wiki/Q5031434","display_name":"Cancer epigenetics","level":5,"score":0.5014262199401855},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.4980795383453369},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.48412904143333435},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.4727141559123993},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.45410358905792236},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.43377578258514404},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.37965530157089233},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.35337352752685547},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.31454548239707947},{"id":"https://openalex.org/C150425827","wikidata":"https://www.wikidata.org/wiki/Q2560317","display_name":"Histone methyltransferase","level":4,"score":0.13684117794036865},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.13366907835006714},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.1123407781124115},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1145/3460238.3460263","is_oa":false,"landing_page_url":"https://doi.org/10.1145/3460238.3460263","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 11th International Conference on Biomedical Engineering and Technology","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8299999833106995}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":48,"referenced_works":["https://openalex.org/W90661041","https://openalex.org/W1504303645","https://openalex.org/W1599295949","https://openalex.org/W1896328371","https://openalex.org/W1963780936","https://openalex.org/W1967342065","https://openalex.org/W1972163114","https://openalex.org/W1976149758","https://openalex.org/W1980240434","https://openalex.org/W1983147439","https://openalex.org/W1998137132","https://openalex.org/W1999478182","https://openalex.org/W2001901628","https://openalex.org/W2008277922","https://openalex.org/W2015754967","https://openalex.org/W2027029112","https://openalex.org/W2043033879","https://openalex.org/W2044433401","https://openalex.org/W2046241907","https://openalex.org/W2054085969","https://openalex.org/W2058308981","https://openalex.org/W2062190843","https://openalex.org/W2089215985","https://openalex.org/W2091203167","https://openalex.org/W2093342054","https://openalex.org/W2093531978","https://openalex.org/W2106482095","https://openalex.org/W2107539126","https://openalex.org/W2107972234","https://openalex.org/W2117247812","https://openalex.org/W2130907138","https://openalex.org/W2139069614","https://openalex.org/W2146329289","https://openalex.org/W2150536104","https://openalex.org/W2164194749","https://openalex.org/W2221837786","https://openalex.org/W2262856750","https://openalex.org/W2290623499","https://openalex.org/W2323939601","https://openalex.org/W2377231095","https://openalex.org/W2411977563","https://openalex.org/W2416995974","https://openalex.org/W2753729734","https://openalex.org/W2890625206","https://openalex.org/W2994655911","https://openalex.org/W2997492439","https://openalex.org/W3102309725","https://openalex.org/W3133248641"],"related_works":["https://openalex.org/W2214376880","https://openalex.org/W3212149434","https://openalex.org/W2073893804","https://openalex.org/W2291484187","https://openalex.org/W3029265673","https://openalex.org/W2104591325","https://openalex.org/W3016572589","https://openalex.org/W2385774039","https://openalex.org/W2118540634","https://openalex.org/W2169213738"],"abstract_inverted_index":{"Cancer":[0],"is":[1],"one":[2],"of":[3,14,31],"the":[4,10,68],"most":[5],"common":[6],"death-leading":[7],"diseases":[8],"in":[9,26,44,49,67],"world,":[11],"affecting":[12],"millions":[13],"people.":[15],"It":[16],"has":[17],"been":[18],"shown":[19],"that":[20],"epigenetics":[21],"plays":[22],"an":[23],"important":[24],"role":[25],"colorectal":[27],"cancer":[28,45,61],"study.":[29],"Roles":[30],"Deoxyribonucleic":[32],"Acid":[33,41],"(DNA)":[34],"methylation,":[35],"Histone":[36],"modification,":[37],"and":[38,62],"non-coding":[39],"Ribonucleic":[40],"(RNA)":[42],"played":[43],"mechanism":[46],"are":[47],"introduced":[48],"this":[50],"review.":[51],"Reviewing":[52],"these":[53],"mechanisms":[54],"can":[55],"help":[56],"to":[57],"understand":[58],"more":[59,64],"about":[60],"develop":[63],"efficient":[65],"therapies":[66],"future.":[69]},"counts_by_year":[],"updated_date":"2026-07-29T14:22:42.915294","created_date":"2025-10-10T00:00:00"}