{"id":"https://openalex.org/W3144344855","doi":"https://doi.org/10.1145/3444884.3444903","title":"The Effect of High Fat Diets on Organic Acids in Mice","display_name":"The Effect of High Fat Diets on Organic Acids in Mice","publication_year":2020,"publication_date":"2020-11-06","ids":{"openalex":"https://openalex.org/W3144344855","doi":"https://doi.org/10.1145/3444884.3444903","mag":"3144344855"},"language":"en","primary_location":{"id":"doi:10.1145/3444884.3444903","is_oa":false,"landing_page_url":"https://doi.org/10.1145/3444884.3444903","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2020 7th International Conference on Biomedical and Bioinformatics Engineering","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100615750","display_name":"Siyang Li","orcid":"https://orcid.org/0000-0001-5479-3999"},"institutions":[{"id":"https://openalex.org/I205237279","display_name":"Nankai University","ror":"https://ror.org/01y1kjr75","country_code":"CN","type":"education","lineage":["https://openalex.org/I205237279"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Siyang Li","raw_affiliation_strings":["Nankai University, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nankai University, China","institution_ids":["https://openalex.org/I205237279"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5100615750"],"corresponding_institution_ids":["https://openalex.org/I205237279"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.46387576,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"100","last_page":"103"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12267","display_name":"Diet and metabolism studies","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/citric-acid-cycle","display_name":"Citric acid cycle","score":0.8485912680625916},{"id":"https://openalex.org/keywords/citric-acid","display_name":"Citric acid","score":0.6393244862556458},{"id":"https://openalex.org/keywords/glycolysis","display_name":"Glycolysis","score":0.6372695565223694},{"id":"https://openalex.org/keywords/organic-acid","display_name":"Organic acid","score":0.6248246431350708},{"id":"https://openalex.org/keywords/lactic-acid","display_name":"Lactic acid","score":0.583195686340332},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.4987618923187256},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.4854162633419037},{"id":"https://openalex.org/keywords/endocrinology","display_name":"Endocrinology","score":0.47944512963294983},{"id":"https://openalex.org/keywords/metabolism","display_name":"Metabolism","score":0.4671351909637451},{"id":"https://openalex.org/keywords/obesity","display_name":"Obesity","score":0.4213699698448181},{"id":"https://openalex.org/keywords/food-science","display_name":"Food science","score":0.42118513584136963},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.3533329963684082},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.24301978945732117},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2246902883052826},{"id":"https://openalex.org/keywords/bacteria","display_name":"Bacteria","score":0.13930076360702515}],"concepts":[{"id":"https://openalex.org/C165135838","wikidata":"https://www.wikidata.org/wiki/Q133895","display_name":"Citric acid cycle","level":3,"score":0.8485912680625916},{"id":"https://openalex.org/C2779032678","wikidata":"https://www.wikidata.org/wiki/Q159683","display_name":"Citric acid","level":2,"score":0.6393244862556458},{"id":"https://openalex.org/C20251656","wikidata":"https://www.wikidata.org/wiki/Q162643","display_name":"Glycolysis","level":3,"score":0.6372695565223694},{"id":"https://openalex.org/C2778715240","wikidata":"https://www.wikidata.org/wiki/Q421948","display_name":"Organic acid","level":2,"score":0.6248246431350708},{"id":"https://openalex.org/C2775920511","wikidata":"https://www.wikidata.org/wiki/Q161249","display_name":"Lactic acid","level":3,"score":0.583195686340332},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4987618923187256},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4854162633419037},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.47944512963294983},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.4671351909637451},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.4213699698448181},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.42118513584136963},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3533329963684082},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.24301978945732117},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2246902883052826},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.13930076360702515},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1145/3444884.3444903","is_oa":false,"landing_page_url":"https://doi.org/10.1145/3444884.3444903","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2020 7th International Conference on Biomedical and Bioinformatics Engineering","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.550000011920929,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W1893330971","https://openalex.org/W1984168891","https://openalex.org/W2007872313","https://openalex.org/W2011729044","https://openalex.org/W2026205682","https://openalex.org/W2042151892","https://openalex.org/W2053313299","https://openalex.org/W2063673863","https://openalex.org/W2087752240","https://openalex.org/W2109253882","https://openalex.org/W2154942270","https://openalex.org/W2467847304","https://openalex.org/W2513735487","https://openalex.org/W2614761965","https://openalex.org/W2905094796","https://openalex.org/W2939175683","https://openalex.org/W2946419455","https://openalex.org/W3038593525","https://openalex.org/W4254626188"],"related_works":["https://openalex.org/W2515776738","https://openalex.org/W2059888780","https://openalex.org/W2393884169","https://openalex.org/W2899493859","https://openalex.org/W1517375172","https://openalex.org/W2392635559","https://openalex.org/W2999943581","https://openalex.org/W2118375422","https://openalex.org/W2900676285","https://openalex.org/W2750790629"],"abstract_inverted_index":{"The":[0,22,81],"high":[1,47],"fat":[2,48],"diet":[3,49],"(HFD)":[4],"is":[5],"the":[6,40,53,66,102,117,123],"main":[7],"cause":[8],"of":[9,24,42,68,83,104,120],"obesity":[10],"and":[11,122],"can":[12],"lead":[13],"to":[14,115],"some":[15,113],"severe":[16,124],"complications":[17],"associated":[18],"with":[19],"metabolic":[20,25],"disorder.":[21],"content":[23,67],"intermediates":[26],"will":[27,36],"change":[28,41,103],"caused":[29],"by":[30,76],"HFD.":[31],"In":[32,52],"this":[33,79],"review,":[34],"we":[35],"report":[37],"studies":[38,95],"about":[39,55],"certain":[43],"organic":[44,105],"acids":[45],"in":[46,96,107],"fed":[50,109],"mice.":[51],"research":[54],"HFD's":[56],"effect":[57,82],"on":[58,65,85,100],"glycolysis,":[59],"HFD":[60,84,108,121],"has":[61],"a":[62],"great":[63],"influence":[64],"pyruvate":[69],"lactic":[70],"acid.":[71],"Different":[72],"hypotheses":[73],"are":[74],"proposed":[75],"researchers":[77,111],"for":[78],"change.":[80],"citric":[86],"cycle":[87],"(TCA":[88],"cycle)":[89],"seems":[90],"not":[91],"clear":[92],"needing":[93],"further":[94],"related":[97],"directions.":[98],"Based":[99],"studying":[101],"acid":[106],"mice,":[110],"provided":[112],"treatments":[114],"mitigate":[116],"negative":[118],"impacts":[119],"complications.":[125]},"counts_by_year":[],"updated_date":"2026-07-29T14:22:42.915294","created_date":"2025-10-10T00:00:00"}