{"id":"https://openalex.org/W3040679844","doi":"https://doi.org/10.1145/3403782.3403803","title":"Identification of Key Genes and Pathways Associated with Chronic Obstructive Pulmonary Disease Based on Bioinformatics Analysis","display_name":"Identification of Key Genes and Pathways Associated with Chronic Obstructive Pulmonary Disease Based on Bioinformatics Analysis","publication_year":2020,"publication_date":"2020-07-04","ids":{"openalex":"https://openalex.org/W3040679844","doi":"https://doi.org/10.1145/3403782.3403803","mag":"3040679844"},"language":"en","primary_location":{"id":"doi:10.1145/3403782.3403803","is_oa":false,"landing_page_url":"https://doi.org/10.1145/3403782.3403803","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the Fourth International Conference on Biological Information and Biomedical Engineering","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090821130","display_name":"Huaiquan Liu","orcid":"https://orcid.org/0000-0002-2394-1554"},"institutions":[{"id":"https://openalex.org/I110640572","display_name":"Guiyang College of Traditional Chinese Medicine","ror":"https://ror.org/02bb8n686","country_code":"CN","type":"education","lineage":["https://openalex.org/I110640572"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Huaiquan Liu","raw_affiliation_strings":["Guizhou University of Traditional Chinese Medicine, Guiyang, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Guizhou University of Traditional Chinese Medicine, Guiyang, China","institution_ids":["https://openalex.org/I110640572"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101592931","display_name":"Yunzhi Chen","orcid":"https://orcid.org/0000-0002-4546-5341"},"institutions":[{"id":"https://openalex.org/I110640572","display_name":"Guiyang College of Traditional Chinese Medicine","ror":"https://ror.org/02bb8n686","country_code":"CN","type":"education","lineage":["https://openalex.org/I110640572"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yunzhi Chen","raw_affiliation_strings":["Guizhou University of Traditional Chinese Medicine, Guiyang, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Guizhou University of Traditional Chinese Medicine, Guiyang, China","institution_ids":["https://openalex.org/I110640572"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100579227","display_name":"Xing Zhu","orcid":null},"institutions":[{"id":"https://openalex.org/I110640572","display_name":"Guiyang College of Traditional Chinese Medicine","ror":"https://ror.org/02bb8n686","country_code":"CN","type":"education","lineage":["https://openalex.org/I110640572"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xing Zhu","raw_affiliation_strings":["Guizhou University of Traditional Chinese Medicine, Guiyang, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Guizhou University of Traditional Chinese Medicine, Guiyang, China","institution_ids":["https://openalex.org/I110640572"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033669420","display_name":"Mengzhi Zhang","orcid":"https://orcid.org/0000-0002-9080-6862"},"institutions":[{"id":"https://openalex.org/I110640572","display_name":"Guiyang College of Traditional Chinese Medicine","ror":"https://ror.org/02bb8n686","country_code":"CN","type":"education","lineage":["https://openalex.org/I110640572"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mengzhi Zhang","raw_affiliation_strings":["Guizhou University of Traditional Chinese Medicine, Guiyang, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Guizhou University of Traditional Chinese Medicine, Guiyang, China","institution_ids":["https://openalex.org/I110640572"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100320279","display_name":"Wen Li","orcid":"https://orcid.org/0000-0002-3975-3312"},"institutions":[{"id":"https://openalex.org/I110640572","display_name":"Guiyang College of Traditional Chinese Medicine","ror":"https://ror.org/02bb8n686","country_code":"CN","type":"education","lineage":["https://openalex.org/I110640572"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wen Li","raw_affiliation_strings":["Guizhou University of Traditional Chinese Medicine, Guiyang, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Guizhou University of Traditional Chinese Medicine, Guiyang, China","institution_ids":["https://openalex.org/I110640572"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.11863163,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"7"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.9574999809265137,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.9108999967575073,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/copd","display_name":"COPD","score":0.8502665758132935},{"id":"https://openalex.org/keywords/pulmonary-disease","display_name":"Pulmonary disease","score":0.8464333415031433},{"id":"https://openalex.org/keywords/pathogenesis","display_name":"Pathogenesis","score":0.7204508781433105},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.5773389935493469},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.553838312625885},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.546773374080658},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.49351203441619873},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.3590603470802307},{"id":"https://openalex.org/keywords/immunology","display_name":"Immunology","score":0.26203644275665283},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2080708146095276},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.205642431974411},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.14135950803756714}],"concepts":[{"id":"https://openalex.org/C2776780178","wikidata":"https://www.wikidata.org/wiki/Q199804","display_name":"COPD","level":2,"score":0.8502665758132935},{"id":"https://openalex.org/C2992779976","wikidata":"https://www.wikidata.org/wiki/Q3286546","display_name":"Pulmonary disease","level":2,"score":0.8464333415031433},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.7204508781433105},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5773389935493469},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.553838312625885},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.546773374080658},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.49351203441619873},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3590603470802307},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.26203644275665283},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2080708146095276},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.205642431974411},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.14135950803756714},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1145/3403782.3403803","is_oa":false,"landing_page_url":"https://doi.org/10.1145/3403782.3403803","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the Fourth International Conference on Biological Information and Biomedical Engineering","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.800000011920929,"display_name":"Good health and well-being"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W1965862880","https://openalex.org/W1976073973","https://openalex.org/W1980810356","https://openalex.org/W2009425023","https://openalex.org/W2021047838","https://openalex.org/W2077258706","https://openalex.org/W2109330762","https://openalex.org/W2145729489","https://openalex.org/W2146994504","https://openalex.org/W2160324372","https://openalex.org/W2165410977","https://openalex.org/W2168877831","https://openalex.org/W2188570991","https://openalex.org/W2509743120","https://openalex.org/W2529622177","https://openalex.org/W2558208069","https://openalex.org/W2767778994","https://openalex.org/W2769274063","https://openalex.org/W2769993902","https://openalex.org/W2788303084","https://openalex.org/W2807814011","https://openalex.org/W2885948165","https://openalex.org/W2889158000","https://openalex.org/W2914824067","https://openalex.org/W2919364499","https://openalex.org/W2924589929","https://openalex.org/W2946938808","https://openalex.org/W2954194044","https://openalex.org/W2965289274","https://openalex.org/W2970031095","https://openalex.org/W2973580856"],"related_works":["https://openalex.org/W2326585857","https://openalex.org/W142525846","https://openalex.org/W2312602415","https://openalex.org/W2312864656","https://openalex.org/W2472126364","https://openalex.org/W2320098543","https://openalex.org/W2585009645","https://openalex.org/W2333131755","https://openalex.org/W4401482945","https://openalex.org/W2372297656"],"abstract_inverted_index":{"Objective:":[0],"Chronic":[1],"obstructive":[2],"pulmonary":[3],"disease":[4,13],"(COPD)":[5],"is":[6,16,25],"recognized":[7],"as":[8],"a":[9],"common":[10],"preventable":[11],"respiratory":[12],"whose":[14],"character":[15],"incompletely":[17],"reversible":[18],"airflow":[19],"limitation.":[20],"However,":[21],"its":[22],"specific":[23],"pathogenesis":[24],"still":[26],"not":[27],"fully":[28],"understood.":[29],"Here":[30],"we":[31],"sought":[32],"to":[33],"identify":[34],"novel":[35],"biomarkers":[36],"or":[37],"targets":[38],"for":[39],"COPD.":[40]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}