{"id":"https://openalex.org/W3039523161","doi":"https://doi.org/10.1145/3397391.3397419","title":"Conditions that Influence Nanoparticle Size and Yield in Nanoparticle Preparation","display_name":"Conditions that Influence Nanoparticle Size and Yield in Nanoparticle Preparation","publication_year":2020,"publication_date":"2020-06-29","ids":{"openalex":"https://openalex.org/W3039523161","doi":"https://doi.org/10.1145/3397391.3397419","mag":"3039523161"},"language":"en","primary_location":{"id":"doi:10.1145/3397391.3397419","is_oa":false,"landing_page_url":"https://doi.org/10.1145/3397391.3397419","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 2020 10th International Conference on Biomedical Engineering and Technology","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103078506","display_name":"Jinghan Qiu","orcid":"https://orcid.org/0000-0002-3881-2042"},"institutions":[{"id":"https://openalex.org/I4210096112","display_name":"Rutgers Sexual and Reproductive Health and Rights","ror":"https://ror.org/00rcvgx40","country_code":"NL","type":"other","lineage":["https://openalex.org/I4210096112"]},{"id":"https://openalex.org/I102322142","display_name":"Rutgers, The State University of New Jersey","ror":"https://ror.org/05vt9qd57","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142"]}],"countries":["NL","US"],"is_corresponding":true,"raw_author_name":"Jinghan Qiu","raw_affiliation_strings":["Rutgers Preparatory School, Highland Park"],"affiliations":[{"raw_affiliation_string":"Rutgers Preparatory School, Highland Park","institution_ids":["https://openalex.org/I102322142","https://openalex.org/I4210096112"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100666923","display_name":"Jie Fu","orcid":"https://orcid.org/0000-0001-5864-3488"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jie Fu","raw_affiliation_strings":["The Wilmer Eye Institute, Johns Hopkins School of Medicine"],"affiliations":[{"raw_affiliation_string":"The Wilmer Eye Institute, Johns Hopkins School of Medicine","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5103078506"],"corresponding_institution_ids":["https://openalex.org/I102322142","https://openalex.org/I4210096112"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.03276987,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"184","last_page":"188"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10079","display_name":"Nanoparticles: synthesis and applications","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12627","display_name":"Graphene and Nanomaterials Applications","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nanoparticle","display_name":"Nanoparticle","score":0.8456728458404541},{"id":"https://openalex.org/keywords/drug-delivery","display_name":"Drug delivery","score":0.6370146870613098},{"id":"https://openalex.org/keywords/plga","display_name":"PLGA","score":0.6215887069702148},{"id":"https://openalex.org/keywords/yield","display_name":"Yield (engineering)","score":0.6013983488082886},{"id":"https://openalex.org/keywords/polyvinyl-alcohol","display_name":"Polyvinyl alcohol","score":0.5764555931091309},{"id":"https://openalex.org/keywords/polyethylene-glycol","display_name":"Polyethylene glycol","score":0.5474286079406738},{"id":"https://openalex.org/keywords/dichloromethane","display_name":"Dichloromethane","score":0.546241819858551},{"id":"https://openalex.org/keywords/particle-size","display_name":"Particle size","score":0.5314242839813232},{"id":"https://openalex.org/keywords/emulsion","display_name":"Emulsion","score":0.5262362360954285},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.5120837688446045},{"id":"https://openalex.org/keywords/polymer","display_name":"Polymer","score":0.5110917687416077},{"id":"https://openalex.org/keywords/microparticle","display_name":"Microparticle","score":0.500108003616333},{"id":"https://openalex.org/keywords/peg-ratio","display_name":"PEG ratio","score":0.4767635464668274},{"id":"https://openalex.org/keywords/chemical-engineering","display_name":"Chemical engineering","score":0.4575587213039398},{"id":"https://openalex.org/keywords/biodegradable-polymer","display_name":"Biodegradable polymer","score":0.44489023089408875},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.4108077585697174},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.3564090132713318},{"id":"https://openalex.org/keywords/organic-chemistry","display_name":"Organic chemistry","score":0.24782365560531616},{"id":"https://openalex.org/keywords/composite-material","display_name":"Composite material","score":0.06562003493309021},{"id":"https://openalex.org/keywords/solvent","display_name":"Solvent","score":0.04397669434547424}],"concepts":[{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.8456728458404541},{"id":"https://openalex.org/C2779820397","wikidata":"https://www.wikidata.org/wiki/Q1392806","display_name":"Drug delivery","level":2,"score":0.6370146870613098},{"id":"https://openalex.org/C2780165375","wikidata":"https://www.wikidata.org/wiki/Q2102907","display_name":"PLGA","level":3,"score":0.6215887069702148},{"id":"https://openalex.org/C134121241","wikidata":"https://www.wikidata.org/wiki/Q899301","display_name":"Yield (engineering)","level":2,"score":0.6013983488082886},{"id":"https://openalex.org/C2778551929","wikidata":"https://www.wikidata.org/wiki/Q146339","display_name":"Polyvinyl alcohol","level":2,"score":0.5764555931091309},{"id":"https://openalex.org/C2776964284","wikidata":"https://www.wikidata.org/wiki/Q410083","display_name":"Polyethylene glycol","level":2,"score":0.5474286079406738},{"id":"https://openalex.org/C2780400988","wikidata":"https://www.wikidata.org/wiki/Q421748","display_name":"Dichloromethane","level":3,"score":0.546241819858551},{"id":"https://openalex.org/C187530423","wikidata":"https://www.wikidata.org/wiki/Q7140503","display_name":"Particle size","level":2,"score":0.5314242839813232},{"id":"https://openalex.org/C2778123984","wikidata":"https://www.wikidata.org/wiki/Q187634","display_name":"Emulsion","level":2,"score":0.5262362360954285},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5120837688446045},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.5110917687416077},{"id":"https://openalex.org/C2777521759","wikidata":"https://www.wikidata.org/wiki/Q61186","display_name":"Microparticle","level":2,"score":0.500108003616333},{"id":"https://openalex.org/C54400483","wikidata":"https://www.wikidata.org/wiki/Q1793202","display_name":"PEG ratio","level":2,"score":0.4767635464668274},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.4575587213039398},{"id":"https://openalex.org/C45211672","wikidata":"https://www.wikidata.org/wiki/Q4119016","display_name":"Biodegradable polymer","level":3,"score":0.44489023089408875},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.4108077585697174},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3564090132713318},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.24782365560531616},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.06562003493309021},{"id":"https://openalex.org/C2780471494","wikidata":"https://www.wikidata.org/wiki/Q146505","display_name":"Solvent","level":2,"score":0.04397669434547424},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C10138342","wikidata":"https://www.wikidata.org/wiki/Q43015","display_name":"Finance","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1145/3397391.3397419","is_oa":false,"landing_page_url":"https://doi.org/10.1145/3397391.3397419","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 2020 10th International Conference on Biomedical Engineering and Technology","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.7900000214576721,"id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":7,"referenced_works":["https://openalex.org/W586465778","https://openalex.org/W1843302206","https://openalex.org/W1964508699","https://openalex.org/W1993410754","https://openalex.org/W2046370080","https://openalex.org/W2172902239","https://openalex.org/W2616129231"],"related_works":["https://openalex.org/W1994780227","https://openalex.org/W2045931316","https://openalex.org/W1599269431","https://openalex.org/W2980944107","https://openalex.org/W2033794127","https://openalex.org/W2983832527","https://openalex.org/W4311717363","https://openalex.org/W1752163733","https://openalex.org/W4321764541","https://openalex.org/W1993507577"],"abstract_inverted_index":{"In":[0,73],"recent":[1],"years,":[2],"there":[3],"is":[4,32,151],"an":[5],"increased":[6],"interest":[7],"in":[8,11,102,117,153,177],"nanoparticles'":[9],"usage":[10],"cancer":[12],"therapies":[13],"to":[14,19,53,64,139],"facilitate":[15],"drug":[16,21,24,42,49,150,176],"delivery.":[17],"Compared":[18],"conventional":[20],"delivery":[22,25,30],"systems,":[23],"that":[26,109],"uses":[27],"nanoparticles":[28,47,84,121,133,162,185],"as":[29,130],"vehicles":[31],"more":[33,187],"precise":[34],"at":[35],"targeting":[36],"sites":[37],"and":[38,58,68,81,91,94,105,119,136,189,194,201,209],"has":[39,168],"a":[40,169,191],"higher":[41],"loading.":[43],"Therefore,":[44],"when":[45,148],"synthesizing":[46],"for":[48,183,195],"delivery,":[50],"it's":[51],"important":[52],"consider":[54],"the":[55,59,66,71,79,131,149,154,160,206],"particles'":[56],"size":[57,104,208],"particles":[60,196],"gained":[61,186],"after":[62],"synthesis":[63,97],"ensure":[65],"quality":[67],"benefits":[69],"of":[70,83],"nanoparticles.":[72],"this":[74],"research,":[75],"we":[76],"have":[77,190],"compared":[78,138],"sizes":[80],"yield":[82,210],"which":[85],"are":[86,134,163,211],"made":[87,141,197],"with":[88,125,142,174,180,198,202],"variable":[89],"conditions":[90,98],"investigated":[92],"if":[93],"how":[95],"different":[96],"may":[99],"cause":[100],"differences":[101],"nanoparticle":[103],"yield.":[106],"We":[107],"concluded":[108],"PEG-PLGA":[110],"(polyethylene":[111],"glycolpoly":[112],"lactic-co-glycolic":[113],"acid)":[114],"polymer":[115],"results":[116],"smaller":[118,165,192],"less":[120,137,181],"than":[122,172],"PLGA2A":[123],"polymer;":[124],"polyvinyl":[126],"alcohol":[127],"(PVA,":[128],"PH=6.8)":[129],"emulsifier,":[132],"larger":[135],"those":[140,173],"phosphate":[143],"buffered":[144],"saline":[145],"(PBS,":[146],"PH=7.4);":[147],"dissolved":[152,175],"organic":[155],"solution":[156,182],"ethyl":[157],"acetate":[158],"(ETAC),":[159],"yielded":[161],"much":[164],"but":[166],"also":[167],"lighter":[170],"weight":[171,188],"Dichloromethane":[178],"(CH2Cl2);":[179],"emulsion,":[184],"size;":[193],"PEG":[199],"(25%)-PLA":[200],"Benzyl":[203],"Alcohol":[204],"added,":[205],"resulting":[207],"both":[212],"larger.":[213]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}