{"id":"https://openalex.org/W2998766410","doi":"https://doi.org/10.1145/3369166.3369193","title":"The Genomic and Transcriptomic Analysis of Stomach Cancer","display_name":"The Genomic and Transcriptomic Analysis of Stomach Cancer","publication_year":2019,"publication_date":"2019-10-23","ids":{"openalex":"https://openalex.org/W2998766410","doi":"https://doi.org/10.1145/3369166.3369193","mag":"2998766410"},"language":"en","primary_location":{"id":"doi:10.1145/3369166.3369193","is_oa":false,"landing_page_url":"https://doi.org/10.1145/3369166.3369193","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 2019 8th International Conference on Bioinformatics and Biomedical Science","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041941913","display_name":"Minyu Chen","orcid":"https://orcid.org/0000-0002-3284-7578"},"institutions":[{"id":"https://openalex.org/I2799291450","display_name":"Oregon Department of Education","ror":"https://ror.org/04pfhbg73","country_code":"US","type":"government","lineage":["https://openalex.org/I2799291450"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Minyu Chen","raw_affiliation_strings":["Oregon Episcopal School"],"affiliations":[{"raw_affiliation_string":"Oregon Episcopal School","institution_ids":["https://openalex.org/I2799291450"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5041941913"],"corresponding_institution_ids":["https://openalex.org/I2799291450"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.29600475,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"80","last_page":"86"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10696","display_name":"Gastric Cancer Management and Outcomes","score":0.9621999859809875,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10696","display_name":"Gastric Cancer Management and Outcomes","score":0.9621999859809875,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10276","display_name":"Helicobacter pylori-related gastroenterology studies","score":0.9606000185012817,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11369","display_name":"Genetic factors in colorectal cancer","score":0.9325000047683716,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/transcriptome","display_name":"Transcriptome","score":0.6273255944252014},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.5501556396484375},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5109847784042358},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4666421711444855},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2665380835533142},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.2110081911087036},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.16420850157737732},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.1012485921382904}],"concepts":[{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.6273255944252014},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5501556396484375},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5109847784042358},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4666421711444855},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2665380835533142},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2110081911087036},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.16420850157737732},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.1012485921382904}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1145/3369166.3369193","is_oa":false,"landing_page_url":"https://doi.org/10.1145/3369166.3369193","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 2019 8th International Conference on Bioinformatics and Biomedical Science","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.7699999809265137,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":2,"referenced_works":["https://openalex.org/W2171439874","https://openalex.org/W4235883944"],"related_works":["https://openalex.org/W2748952813","https://openalex.org/W2399513595","https://openalex.org/W4388386498","https://openalex.org/W2028462563","https://openalex.org/W2390279801","https://openalex.org/W2982720988","https://openalex.org/W2358668433","https://openalex.org/W2376932109","https://openalex.org/W3150324899","https://openalex.org/W2001405890"],"abstract_inverted_index":{"The":[0,148],"increasing":[1],"number":[2,83],"in":[3,44,154,181],"cancer":[4,61,79],"population":[5],"necessitates":[6],"the":[7,13,82,93,121,126,157,172,185,189],"urgency":[8],"for":[9],"studying":[10],"cancer.":[11],"Cancer,":[12],"abnormal":[14],"proliferation":[15],"of":[16,58,76,86,96,113,133,156,163,188,192],"cells":[17],"arising":[18],"from":[19,65,70,105],"a":[20,29],"particular":[21],"organ":[22],"and":[23,39,46,68,84,107,116,146,195,209],"metastasizing":[24],"to":[25],"nearby":[26],"areas,":[27],"is":[28,40],"general":[30],"category":[31],"that":[32,201],"contains":[33],"more":[34],"than":[35],"100":[36],"fatal":[37],"diseases":[38],"caused":[41],"by":[42,102],"alterations":[43],"oncogenes":[45],"tumor":[47,66,117,124,166,182],"suppressor":[48,118],"genes.":[49],"This":[50],"project":[51],"adopted":[52],"whole":[53],"exome":[54],"sequencing":[55,127],"(DNA)":[56],"data":[57,104],"6":[59,64,77,158],"stomach":[60,78,97],"patients":[62,80],"including":[63],"tissues":[67],"3":[69],"adjacent":[71],"normal":[72,170],"tissues.":[73,183],"Genomic":[74],"analysis":[75,91,112,162],"revealed":[81],"frequency":[85],"mutated":[87,174],"genes":[88,119],"while":[89],"transcriptomic":[90,161],"indicated":[92,200],"protein":[94],"profiling":[95],"cancer,":[98],"which":[99],"was":[100,152,177],"performed":[101],"retrieving":[103],"TCGA":[106],"TEGx":[108],"database.":[109],"For":[110],"genomic":[111],"common":[114,149],"oncogene":[115,150],"comparing":[120],"six":[122],"patients'":[123,165,197,210],"tissue,":[125],"results":[128],"identified":[129],"5":[130,155],"different":[131],"types":[132],"mutations":[134],"containing":[135],"SNV":[136],"(single":[137],"nucleotide":[138,142],"variation),":[139,143],"MNV":[140],"(multiple":[141],"insertion,":[144],"deletion":[145],"replacement.":[147],"BCR":[151],"found":[153,178],"patients.":[159],"In":[160],"three":[164],"gene":[167,175],"subtract":[168],"their":[169],"gene,":[171],"shared":[173],"MUC3A":[176,193],"significantly":[179],"over-expressed":[180],"Finally,":[184],"high":[186],"p-value":[187],"survival":[190,198],"curve":[191],"expression":[194],"predicted":[196],"conditions":[199],"there's":[202],"no":[203],"statistically-significant":[204],"correlation":[205],"between":[206],"MUC3A's":[207],"over-expressions":[208],"survival.":[211]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}