{"id":"https://openalex.org/W3008373904","doi":"https://doi.org/10.1145/3368826.3377925","title":"A performance-optimizing compiler for cyber-physical digital microfluidic biochips","display_name":"A performance-optimizing compiler for cyber-physical digital microfluidic biochips","publication_year":2020,"publication_date":"2020-02-21","ids":{"openalex":"https://openalex.org/W3008373904","doi":"https://doi.org/10.1145/3368826.3377925","mag":"3008373904"},"language":"en","primary_location":{"id":"doi:10.1145/3368826.3377925","is_oa":true,"landing_page_url":"https://doi.org/10.1145/3368826.3377925","pdf_url":"https://dl.acm.org/doi/pdf/10.1145/3368826.3377925","source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 18th ACM/IEEE International Symposium on Code Generation and Optimization","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://dl.acm.org/doi/pdf/10.1145/3368826.3377925","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033656515","display_name":"Tyson Loveless","orcid":"https://orcid.org/0000-0001-5081-6516"},"institutions":[{"id":"https://openalex.org/I103635307","display_name":"University of California, Riverside","ror":"https://ror.org/03nawhv43","country_code":"US","type":"education","lineage":["https://openalex.org/I103635307"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Tyson Loveless","raw_affiliation_strings":["University of California at Riverside, USA"],"affiliations":[{"raw_affiliation_string":"University of California at Riverside, USA","institution_ids":["https://openalex.org/I103635307"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000056801","display_name":"Jason Ott","orcid":"https://orcid.org/0000-0002-8725-1771"},"institutions":[{"id":"https://openalex.org/I103635307","display_name":"University of California, Riverside","ror":"https://ror.org/03nawhv43","country_code":"US","type":"education","lineage":["https://openalex.org/I103635307"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jason Ott","raw_affiliation_strings":["University of California at Riverside, USA"],"affiliations":[{"raw_affiliation_string":"University of California at Riverside, USA","institution_ids":["https://openalex.org/I103635307"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011244614","display_name":"Philip Brisk","orcid":"https://orcid.org/0000-0003-0083-9781"},"institutions":[{"id":"https://openalex.org/I103635307","display_name":"University of California, Riverside","ror":"https://ror.org/03nawhv43","country_code":"US","type":"education","lineage":["https://openalex.org/I103635307"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Philip Brisk","raw_affiliation_strings":["University of California at Riverside, USA"],"affiliations":[{"raw_affiliation_string":"University of California at Riverside, USA","institution_ids":["https://openalex.org/I103635307"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5033656515"],"corresponding_institution_ids":["https://openalex.org/I103635307"],"apc_list":null,"apc_paid":null,"fwci":1.1441,"has_fulltext":true,"cited_by_count":12,"citation_normalized_percentile":{"value":0.77575668,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":null,"issue":null,"first_page":"171","last_page":"184"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12452","display_name":"Electrowetting and Microfluidic Technologies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12452","display_name":"Electrowetting and Microfluidic Technologies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12784","display_name":"Modular Robots and Swarm Intelligence","score":0.989799976348877,"subfield":{"id":"https://openalex.org/subfields/2210","display_name":"Mechanical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10299","display_name":"Photonic and Optical Devices","score":0.9729999899864197,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/compiler","display_name":"Compiler","score":0.8463627099990845},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.8188566565513611},{"id":"https://openalex.org/keywords/embedded-system","display_name":"Embedded system","score":0.5516777634620667},{"id":"https://openalex.org/keywords/software","display_name":"Software","score":0.5221369862556458},{"id":"https://openalex.org/keywords/scheduling","display_name":"Scheduling (production processes)","score":0.4852185547351837},{"id":"https://openalex.org/keywords/overhead","display_name":"Overhead (engineering)","score":0.46057793498039246},{"id":"https://openalex.org/keywords/field-programmable-gate-array","display_name":"Field-programmable gate array","score":0.44402509927749634},{"id":"https://openalex.org/keywords/biochip","display_name":"Biochip","score":0.4254208207130432},{"id":"https://openalex.org/keywords/latency","display_name":"Latency (audio)","score":0.4242652356624603},{"id":"https://openalex.org/keywords/computer-hardware","display_name":"Computer hardware","score":0.3543385863304138},{"id":"https://openalex.org/keywords/parallel-computing","display_name":"Parallel computing","score":0.3531787395477295},{"id":"https://openalex.org/keywords/operating-system","display_name":"Operating system","score":0.23248758912086487}],"concepts":[{"id":"https://openalex.org/C169590947","wikidata":"https://www.wikidata.org/wiki/Q47506","display_name":"Compiler","level":2,"score":0.8463627099990845},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.8188566565513611},{"id":"https://openalex.org/C149635348","wikidata":"https://www.wikidata.org/wiki/Q193040","display_name":"Embedded system","level":1,"score":0.5516777634620667},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.5221369862556458},{"id":"https://openalex.org/C206729178","wikidata":"https://www.wikidata.org/wiki/Q2271896","display_name":"Scheduling (production processes)","level":2,"score":0.4852185547351837},{"id":"https://openalex.org/C2779960059","wikidata":"https://www.wikidata.org/wiki/Q7113681","display_name":"Overhead (engineering)","level":2,"score":0.46057793498039246},{"id":"https://openalex.org/C42935608","wikidata":"https://www.wikidata.org/wiki/Q190411","display_name":"Field-programmable gate array","level":2,"score":0.44402509927749634},{"id":"https://openalex.org/C87892846","wikidata":"https://www.wikidata.org/wiki/Q864256","display_name":"Biochip","level":2,"score":0.4254208207130432},{"id":"https://openalex.org/C82876162","wikidata":"https://www.wikidata.org/wiki/Q17096504","display_name":"Latency (audio)","level":2,"score":0.4242652356624603},{"id":"https://openalex.org/C9390403","wikidata":"https://www.wikidata.org/wiki/Q3966","display_name":"Computer hardware","level":1,"score":0.3543385863304138},{"id":"https://openalex.org/C173608175","wikidata":"https://www.wikidata.org/wiki/Q232661","display_name":"Parallel computing","level":1,"score":0.3531787395477295},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.23248758912086487},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C21547014","wikidata":"https://www.wikidata.org/wiki/Q1423657","display_name":"Operations management","level":1,"score":0.0},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.0},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.0},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1145/3368826.3377925","is_oa":true,"landing_page_url":"https://doi.org/10.1145/3368826.3377925","pdf_url":"https://dl.acm.org/doi/pdf/10.1145/3368826.3377925","source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 18th ACM/IEEE International Symposium on Code Generation and Optimization","raw_type":"proceedings-article"}],"best_oa_location":{"id":"doi:10.1145/3368826.3377925","is_oa":true,"landing_page_url":"https://doi.org/10.1145/3368826.3377925","pdf_url":"https://dl.acm.org/doi/pdf/10.1145/3368826.3377925","source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 18th ACM/IEEE International Symposium on Code Generation and Optimization","raw_type":"proceedings-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1006491643","display_name":null,"funder_award_id":"1910878","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G3118365980","display_name":null,"funder_award_id":"1545097","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G6166098498","display_name":null,"funder_award_id":"1351115","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G6528768137","display_name":"AitF: EXPL: Algorithmic Fluid Concentration Management for Programmable Microfluidics","funder_award_id":"1536026","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G6808804343","display_name":null,"funder_award_id":"1351115, 1536026, 1545097, 1910878","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3008373904.pdf","grobid_xml":"https://content.openalex.org/works/W3008373904.grobid-xml"},"referenced_works_count":93,"referenced_works":["https://openalex.org/W1536801036","https://openalex.org/W1555946919","https://openalex.org/W1784990824","https://openalex.org/W1909235131","https://openalex.org/W1968000836","https://openalex.org/W1986626819","https://openalex.org/W1987919377","https://openalex.org/W1988889038","https://openalex.org/W1991280614","https://openalex.org/W1993559980","https://openalex.org/W1995283842","https://openalex.org/W2000163493","https://openalex.org/W2003672926","https://openalex.org/W2003804316","https://openalex.org/W2013470780","https://openalex.org/W2016729208","https://openalex.org/W2018208873","https://openalex.org/W2018502987","https://openalex.org/W2018790814","https://openalex.org/W2024137802","https://openalex.org/W2029481052","https://openalex.org/W2030184574","https://openalex.org/W2032239903","https://openalex.org/W2034121290","https://openalex.org/W2037691108","https://openalex.org/W2041473945","https://openalex.org/W2043456245","https://openalex.org/W2044636417","https://openalex.org/W2044935944","https://openalex.org/W2051012691","https://openalex.org/W2058157955","https://openalex.org/W2062812113","https://openalex.org/W2067873275","https://openalex.org/W2072916763","https://openalex.org/W2074519556","https://openalex.org/W2074880148","https://openalex.org/W2079543149","https://openalex.org/W2082198782","https://openalex.org/W2084703732","https://openalex.org/W2086814414","https://openalex.org/W2088122327","https://openalex.org/W2095801487","https://openalex.org/W2099652466","https://openalex.org/W2105067004","https://openalex.org/W2106375434","https://openalex.org/W2107342278","https://openalex.org/W2115153870","https://openalex.org/W2116375684","https://openalex.org/W2118866757","https://openalex.org/W2119985798","https://openalex.org/W2121689340","https://openalex.org/W2121993001","https://openalex.org/W2122651297","https://openalex.org/W2123978582","https://openalex.org/W2124253086","https://openalex.org/W2126105956","https://openalex.org/W2130933259","https://openalex.org/W2140191557","https://openalex.org/W2142436226","https://openalex.org/W2142581655","https://openalex.org/W2145106285","https://openalex.org/W2147820467","https://openalex.org/W2148720935","https://openalex.org/W2151013793","https://openalex.org/W2155074420","https://openalex.org/W2157834370","https://openalex.org/W2159969440","https://openalex.org/W2164654755","https://openalex.org/W2166910382","https://openalex.org/W2167304422","https://openalex.org/W2168567259","https://openalex.org/W2168958225","https://openalex.org/W2170884232","https://openalex.org/W2186102677","https://openalex.org/W2199074684","https://openalex.org/W2284787681","https://openalex.org/W2340881701","https://openalex.org/W2344160642","https://openalex.org/W2510233378","https://openalex.org/W2517695883","https://openalex.org/W2616585943","https://openalex.org/W2738687125","https://openalex.org/W2762896201","https://openalex.org/W2791275605","https://openalex.org/W2851940946","https://openalex.org/W2898284134","https://openalex.org/W2935677582","https://openalex.org/W3148529197","https://openalex.org/W4237011848","https://openalex.org/W4240296317","https://openalex.org/W4244008682","https://openalex.org/W4254228661","https://openalex.org/W4254807835"],"related_works":["https://openalex.org/W2364922518","https://openalex.org/W1995422305","https://openalex.org/W2361860382","https://openalex.org/W2379531326","https://openalex.org/W2604557458","https://openalex.org/W1834829329","https://openalex.org/W2544485685","https://openalex.org/W2599588613","https://openalex.org/W2353006359","https://openalex.org/W4313814494"],"abstract_inverted_index":{"This":[0],"paper":[1],"introduces":[2],"a":[3,15,25,36,102,117,152,156,160],"compiler":[4,23,97,135],"optimization":[5,51],"strategy":[6,52],"for":[7,80],"Software-Programmable":[8],"Laboratories-on-a-Chip":[9],"(SP-LoCs),":[10],"which":[11],"miniaturize":[12],"and":[13,65,71,136,166],"automate":[14],"wide":[16],"variety":[17],"of":[18,28,60,74,89,109],"benchtop":[19],"laboratory":[20],"experiments.":[21],"The":[22,50,96],"targets":[24],"specific":[26],"class":[27],"SP-LoCs":[29],"that":[30,105,116,144,173],"manipulate":[31],"discrete":[32],"liquid":[33],"droplets":[34],"on":[35],"2D":[37],"grid,":[38],"with":[39],"cyber-physical":[40],"feedback":[41],"provided":[42],"by":[43,121,147],"integrated":[44],"sensors":[45],"and/or":[46],"video":[47],"monitoring":[48],"equipment.":[49],"employed":[53],"here":[54],"aims":[55],"to":[56,93],"reduce":[57],"the":[58,69,87,107,110,134,167],"overhead":[59],"transporting":[61],"fluids":[62],"between":[63,68,155],"operations,":[64,149],"explores":[66],"tradeoffs":[67],"latency":[70],"resource":[72,164],"requirements":[73],"mixing":[75,81,83,148,162],"operations:":[76],"allocating":[77],"more":[78],"space":[79],"shortens":[82],"time,":[84],"but":[85],"reduces":[86,127],"amount":[88],"spatial":[90],"parallelism":[91],"available":[92],"other":[94],"operations.":[95],"is":[98,174],"empirically":[99],"evaluated":[100],"using":[101,159],"cycle-accurate":[103],"simulator":[104],"mimics":[106],"behavior":[108],"target":[111],"SP-LoC.":[112],"Our":[113],"results":[114],"show":[115],"coalescing":[118],"strategy,":[119],"inspired":[120],"graph":[122],"coloring":[123],"register":[124],"allocation,":[125],"effectively":[126],"droplet":[128],"transport":[129],"latencies":[130],"while":[131],"speeding":[132],"up":[133],"reducing":[137],"its":[138],"memory":[139],"footprint.":[140],"For":[141],"biochemical":[142],"reactions":[143],"are":[145],"dominated":[146],"we":[150],"observe":[151],"linear":[153],"correlation":[154],"preliminary":[157],"result":[158],"default":[161],"operation":[163],"allocation":[165],"percentage":[168],"decrease":[169],"in":[170],"execution":[171],"time":[172],"achieved":[175],"via":[176],"resizing.":[177]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2}],"updated_date":"2026-04-21T08:09:41.155169","created_date":"2025-10-10T00:00:00"}