{"id":"https://openalex.org/W2911419886","doi":"https://doi.org/10.1145/3308558.3313476","title":"Modeling Relational Drug-Target-Disease Interactions via Tensor Factorization with Multiple Web Sources","display_name":"Modeling Relational Drug-Target-Disease Interactions via Tensor Factorization with Multiple Web Sources","publication_year":2019,"publication_date":"2019-05-13","ids":{"openalex":"https://openalex.org/W2911419886","doi":"https://doi.org/10.1145/3308558.3313476","mag":"2911419886"},"language":"en","primary_location":{"id":"doi:10.1145/3308558.3313476","is_oa":true,"landing_page_url":"https://doi.org/10.1145/3308558.3313476","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The World Wide Web Conference","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1145/3308558.3313476","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004341287","display_name":"Huiyuan Chen","orcid":"https://orcid.org/0000-0002-6360-558X"},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Huiyuan Chen","raw_affiliation_strings":["Case Western Reserve University, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Case Western Reserve University, USA","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100337051","display_name":"Jing Li","orcid":"https://orcid.org/0000-0003-1160-6959"},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jing Li","raw_affiliation_strings":["Case Western Reserve University, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Case Western Reserve University, USA","institution_ids":["https://openalex.org/I58956616"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I58956616"],"apc_list":null,"apc_paid":null,"fwci":20.0999,"has_fulltext":false,"cited_by_count":36,"citation_normalized_percentile":{"value":0.99338704,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":null,"issue":null,"first_page":"218","last_page":"227"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9843999743461609,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9843999743461609,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9736999869346619,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12303","display_name":"Tensor decomposition and applications","score":0.9659000039100647,"subfield":{"id":"https://openalex.org/subfields/2605","display_name":"Computational Mathematics"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7114073634147644},{"id":"https://openalex.org/keywords/the-internet","display_name":"The Internet","score":0.6194809675216675},{"id":"https://openalex.org/keywords/drug","display_name":"Drug","score":0.5842159986495972},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.5729703903198242},{"id":"https://openalex.org/keywords/drug-discovery","display_name":"Drug discovery","score":0.47200536727905273},{"id":"https://openalex.org/keywords/precision-medicine","display_name":"Precision medicine","score":0.45436954498291016},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.433709055185318},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.20413079857826233},{"id":"https://openalex.org/keywords/world-wide-web","display_name":"World Wide Web","score":0.20143678784370422},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.14651069045066833},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.11404871940612793},{"id":"https://openalex.org/keywords/pharmacology","display_name":"Pharmacology","score":0.09847313165664673}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7114073634147644},{"id":"https://openalex.org/C110875604","wikidata":"https://www.wikidata.org/wiki/Q75","display_name":"The Internet","level":2,"score":0.6194809675216675},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.5842159986495972},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5729703903198242},{"id":"https://openalex.org/C74187038","wikidata":"https://www.wikidata.org/wiki/Q1418791","display_name":"Drug discovery","level":2,"score":0.47200536727905273},{"id":"https://openalex.org/C163763905","wikidata":"https://www.wikidata.org/wiki/Q17075943","display_name":"Precision medicine","level":2,"score":0.45436954498291016},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.433709055185318},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.20413079857826233},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.20143678784370422},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.14651069045066833},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.11404871940612793},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.09847313165664673},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1145/3308558.3313476","is_oa":true,"landing_page_url":"https://doi.org/10.1145/3308558.3313476","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The World Wide Web Conference","raw_type":"proceedings-article"}],"best_oa_location":{"id":"doi:10.1145/3308558.3313476","is_oa":true,"landing_page_url":"https://doi.org/10.1145/3308558.3313476","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The World Wide Web Conference","raw_type":"proceedings-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":50,"referenced_works":["https://openalex.org/W1632866817","https://openalex.org/W1804110266","https://openalex.org/W1971106435","https://openalex.org/W1976801265","https://openalex.org/W1984084871","https://openalex.org/W1998898494","https://openalex.org/W2024165284","https://openalex.org/W2029348196","https://openalex.org/W2045512849","https://openalex.org/W2049588365","https://openalex.org/W2056088289","https://openalex.org/W2061716729","https://openalex.org/W2071478164","https://openalex.org/W2085269748","https://openalex.org/W2091449379","https://openalex.org/W2110349231","https://openalex.org/W2113072832","https://openalex.org/W2117486996","https://openalex.org/W2151357092","https://openalex.org/W2153838454","https://openalex.org/W2154896031","https://openalex.org/W2157789635","https://openalex.org/W2162452562","https://openalex.org/W2165874743","https://openalex.org/W2167623372","https://openalex.org/W2251053287","https://openalex.org/W2256119113","https://openalex.org/W2279323413","https://openalex.org/W2284713259","https://openalex.org/W2325410115","https://openalex.org/W2343107734","https://openalex.org/W2407024508","https://openalex.org/W2515537108","https://openalex.org/W2535406655","https://openalex.org/W2549348365","https://openalex.org/W2558217333","https://openalex.org/W2604617820","https://openalex.org/W2613004929","https://openalex.org/W2746173003","https://openalex.org/W2747147629","https://openalex.org/W2765153686","https://openalex.org/W2771079411","https://openalex.org/W2786016794","https://openalex.org/W2787904349","https://openalex.org/W2793951981","https://openalex.org/W2799915114","https://openalex.org/W2898346288","https://openalex.org/W2907272802","https://openalex.org/W2999320195","https://openalex.org/W4205293427"],"related_works":["https://openalex.org/W4200407670","https://openalex.org/W2065457896","https://openalex.org/W3173234801","https://openalex.org/W2480711475","https://openalex.org/W2167984027","https://openalex.org/W3021302227","https://openalex.org/W10630519","https://openalex.org/W1919377569","https://openalex.org/W3144288563","https://openalex.org/W3123907821"],"abstract_inverted_index":{"Modeling":[0],"the":[1,9,34,63],"behaviors":[2],"of":[3,12,28,31,39,71],"drug-target-disease":[4],"interactions":[5,56,59],"is":[6],"crucial":[7],"in":[8],"early":[10],"stage":[11],"drug":[13],"discovery":[14],"and":[15,22,48],"holds":[16],"great":[17,37],"promise":[18],"for":[19],"precision":[20],"medicine":[21],"personalized":[23],"treatments.":[24],"The":[25],"growing":[26],"availability":[27],"new":[29],"types":[30],"data":[32],"on":[33],"internet":[35],"brings":[36],"opportunity":[38],"learning":[40],"a":[41],"more":[42],"comprehensive":[43],"relationship":[44],"among":[45,65],"drugs,":[46],"targets,":[47],"diseases.":[49],"However,":[50],"existing":[51],"methods":[52],"often":[53],"consider":[54],"drug-target":[55],"or":[57],"drug-disease":[58],"separately,":[60],"which":[61],"ignores":[62],"dependencies":[64],"these":[66],"three":[67],"entities.":[68],"Also,":[69],"many":[70],"them":[72],"cannot":[73],"directly":[74],"incorporate":[75],"rich":[76],"heterogeneous":[77],"information":[78],"from":[79],"diverse":[80],"sources.":[81]},"counts_by_year":[{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":5}],"updated_date":"2026-07-30T17:31:21.811387","created_date":"2025-10-10T00:00:00"}