{"id":"https://openalex.org/W2888604704","doi":"https://doi.org/10.1145/3208955.3208973","title":"Scanned Laser Pico-Projection Image Processing for Cancer-Like Cells Induced by Isopropyl \u03b2-D-1-thiogalactopyranoside","display_name":"Scanned Laser Pico-Projection Image Processing for Cancer-Like Cells Induced by Isopropyl \u03b2-D-1-thiogalactopyranoside","publication_year":2018,"publication_date":"2018-04-23","ids":{"openalex":"https://openalex.org/W2888604704","doi":"https://doi.org/10.1145/3208955.3208973","mag":"2888604704"},"language":"en","primary_location":{"id":"doi:10.1145/3208955.3208973","is_oa":false,"landing_page_url":"https://doi.org/10.1145/3208955.3208973","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 2018 8th International Conference on Biomedical Engineering and Technology","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063384458","display_name":"Yi\u2010Hsuan Wu","orcid":"https://orcid.org/0000-0003-2366-8268"},"institutions":[{"id":"https://openalex.org/I152743029","display_name":"Kaohsiung Medical University","ror":"https://ror.org/03gk81f96","country_code":"TW","type":"education","lineage":["https://openalex.org/I152743029"]}],"countries":["TW"],"is_corresponding":true,"raw_author_name":"Yi-Hsuan Wu","raw_affiliation_strings":["Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung, Taiwan"],"affiliations":[{"raw_affiliation_string":"Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung, Taiwan","institution_ids":["https://openalex.org/I152743029"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036338785","display_name":"Wen\u2010Tai Chiu","orcid":"https://orcid.org/0000-0003-0310-0675"},"institutions":[{"id":"https://openalex.org/I91807558","display_name":"National Cheng Kung University","ror":"https://ror.org/01b8kcc49","country_code":"TW","type":"education","lineage":["https://openalex.org/I91807558"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Wen-Tai Chiu","raw_affiliation_strings":["Department of Biomedical Engineering, National Cheng Kung University, Taiwan"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, National Cheng Kung University, Taiwan","institution_ids":["https://openalex.org/I91807558"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048254745","display_name":"Mengjia Lian","orcid":"https://orcid.org/0009-0007-6184-5807"},"institutions":[{"id":"https://openalex.org/I152743029","display_name":"Kaohsiung Medical University","ror":"https://ror.org/03gk81f96","country_code":"TW","type":"education","lineage":["https://openalex.org/I152743029"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Meng-Jia Lian","raw_affiliation_strings":["School of Dentistry, Kaohsiung Medical University, Kaohsiung, Taiwan"],"affiliations":[{"raw_affiliation_string":"School of Dentistry, Kaohsiung Medical University, Kaohsiung, Taiwan","institution_ids":["https://openalex.org/I152743029"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062051776","display_name":"Chih\u2010Ling Huang","orcid":"https://orcid.org/0000-0002-7323-4954"},"institutions":[{"id":"https://openalex.org/I152743029","display_name":"Kaohsiung Medical University","ror":"https://ror.org/03gk81f96","country_code":"TW","type":"education","lineage":["https://openalex.org/I152743029"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chih-Ling Huang","raw_affiliation_strings":["Center for Fundamental Science, Kaohsiung Medical University, Kaohsiung, Taiwan"],"affiliations":[{"raw_affiliation_string":"Center for Fundamental Science, Kaohsiung Medical University, Kaohsiung, Taiwan","institution_ids":["https://openalex.org/I152743029"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5063384458"],"corresponding_institution_ids":["https://openalex.org/I152743029"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.12259962,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"61","last_page":"64"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.9929999709129333,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.9929999709129333,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14331","display_name":"Medicinal Plant Pharmacodynamics Research","score":0.9732000231742859,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9617999792098999,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oncogene","display_name":"Oncogene","score":0.6033210158348083},{"id":"https://openalex.org/keywords/cancer-cell","display_name":"Cancer cell","score":0.5977032780647278},{"id":"https://openalex.org/keywords/gray-level","display_name":"Gray level","score":0.5461288094520569},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.4567282795906067},{"id":"https://openalex.org/keywords/isopropyl","display_name":"Isopropyl","score":0.4279627799987793},{"id":"https://openalex.org/keywords/fibroblast","display_name":"Fibroblast","score":0.4261896014213562},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.4238452911376953},{"id":"https://openalex.org/keywords/basal-cell","display_name":"Basal cell","score":0.4141029119491577},{"id":"https://openalex.org/keywords/cell","display_name":"Cell","score":0.41185590624809265},{"id":"https://openalex.org/keywords/cancer-research","display_name":"Cancer research","score":0.3246530592441559},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3037356734275818},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.2988879084587097},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.2966998517513275},{"id":"https://openalex.org/keywords/cell-culture","display_name":"Cell culture","score":0.2807813882827759},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.20135408639907837},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.18070396780967712},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.1416347622871399},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.12220796942710876},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.10188218951225281},{"id":"https://openalex.org/keywords/cell-cycle","display_name":"Cell cycle","score":0.08612462878227234}],"concepts":[{"id":"https://openalex.org/C2781018059","wikidata":"https://www.wikidata.org/wiki/Q207609","display_name":"Oncogene","level":4,"score":0.6033210158348083},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.5977032780647278},{"id":"https://openalex.org/C2985861186","wikidata":"https://www.wikidata.org/wiki/Q685727","display_name":"Gray level","level":3,"score":0.5461288094520569},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4567282795906067},{"id":"https://openalex.org/C104264131","wikidata":"https://www.wikidata.org/wiki/Q898637","display_name":"Isopropyl","level":2,"score":0.4279627799987793},{"id":"https://openalex.org/C2780381497","wikidata":"https://www.wikidata.org/wiki/Q463418","display_name":"Fibroblast","level":3,"score":0.4261896014213562},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4238452911376953},{"id":"https://openalex.org/C3019992690","wikidata":"https://www.wikidata.org/wiki/Q92767510","display_name":"Basal cell","level":2,"score":0.4141029119491577},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.41185590624809265},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3246530592441559},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3037356734275818},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2988879084587097},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2966998517513275},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.2807813882827759},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.20135408639907837},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.18070396780967712},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1416347622871399},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.12220796942710876},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.10188218951225281},{"id":"https://openalex.org/C29537977","wikidata":"https://www.wikidata.org/wiki/Q188941","display_name":"Cell cycle","level":3,"score":0.08612462878227234},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1145/3208955.3208973","is_oa":false,"landing_page_url":"https://doi.org/10.1145/3208955.3208973","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 2018 8th International Conference on Biomedical Engineering and Technology","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322811","display_name":"Kaohsiung Medical University","ror":"https://ror.org/03gk81f96"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W1550780731","https://openalex.org/W1963965802","https://openalex.org/W1964847767","https://openalex.org/W1978985990","https://openalex.org/W1986383243","https://openalex.org/W1987473368","https://openalex.org/W1992329208","https://openalex.org/W1997201725","https://openalex.org/W1997568228","https://openalex.org/W2041539419","https://openalex.org/W2045659778","https://openalex.org/W2046170350","https://openalex.org/W2046303868","https://openalex.org/W2050562341","https://openalex.org/W2077462602","https://openalex.org/W2081935558","https://openalex.org/W2089270751","https://openalex.org/W2093680491","https://openalex.org/W2104584000","https://openalex.org/W2122572948","https://openalex.org/W2124242440","https://openalex.org/W2156417547","https://openalex.org/W2156734818","https://openalex.org/W2169379435","https://openalex.org/W2324853856","https://openalex.org/W2463615816","https://openalex.org/W2518773165"],"related_works":["https://openalex.org/W1983104880","https://openalex.org/W2967904358","https://openalex.org/W2081195959","https://openalex.org/W2089922573","https://openalex.org/W18267513","https://openalex.org/W2950222181","https://openalex.org/W2050014257","https://openalex.org/W2334336510","https://openalex.org/W2517703720","https://openalex.org/W4233312932"],"abstract_inverted_index":{"Compared":[0],"to":[1,22,60,62],"normal":[2,76,97],"cells,":[3],"cancer":[4,119],"cells":[5,67,77],"have":[6,81],"unique":[7],"characteristic":[8],"in":[9],"oncogene":[10,26],"and":[11,69,79,85,92,101,105],"morphology.":[12,43],"Isopropyl":[13],"\u03b2-D-1-thiogalactopyranoside":[14],"(IPTG)":[15],"can":[16,95,112],"be":[17],"used":[18],"as":[19],"an":[20],"inducer":[21],"trigger":[23],"transcription":[24],"of":[25,41,118],"Ha-ras.":[27],"Scanned":[28],"Laser":[29],"Pico-Projection":[30],"(SLPP)":[31],"image":[32,58],"provide":[33],"a":[34,54],"texture":[35],"enhancement":[36],"effect":[37],"for":[38,57],"analyzing":[39],"features":[40],"cell":[42,116],"In":[44],"this":[45],"study,":[46],"we":[47],"also":[48],"use":[49],"Gray-level":[50],"Co-occurrence":[51],"Matrix":[52],"(GLCM),":[53],"common":[55],"method":[56],"processing,":[59],"analyze":[61],"morphology":[63],"texture.":[64],"The":[65],"cancer-like":[66,99],"(MK4":[68],"7-4":[70],"cells)":[71],"induced":[72],"by":[73],"IPTG":[74],"from":[75],"(MDCK":[78],"NIH-3T3)":[80],"the":[82,88,114],"higher":[83],"Contrast":[84],"Entropy,":[86],"but":[87],"lower":[89],"Correlation,":[90],"Homogeneity,":[91],"Energy.":[93],"It":[94,108],"differentiate":[96],"&":[98],"pairs":[100],"works":[102],"on":[103],"epithelial":[104],"fibroblast":[106],"cells.":[107],"means":[109],"that":[110],"it":[111],"classify":[113],"major":[115],"species":[117],"occurrence.":[120]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}