{"id":"https://openalex.org/W2558003273","doi":"https://doi.org/10.1145/2975167.2975183","title":"Automatic Detection of Beta-barrel from Medium Resolution Cryo-EM Density Maps","display_name":"Automatic Detection of Beta-barrel from Medium Resolution Cryo-EM Density Maps","publication_year":2016,"publication_date":"2016-10-02","ids":{"openalex":"https://openalex.org/W2558003273","doi":"https://doi.org/10.1145/2975167.2975183","mag":"2558003273"},"language":"en","primary_location":{"id":"doi:10.1145/2975167.2975183","is_oa":false,"landing_page_url":"https://doi.org/10.1145/2975167.2975183","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 7th ACM International Conference on Bioinformatics, Computational Biology, and Health Informatics","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5080683855","display_name":"Dong Si","orcid":"https://orcid.org/0000-0001-7039-2589"},"institutions":[{"id":"https://openalex.org/I4210138624","display_name":"University of Washington Bothell","ror":"https://ror.org/02ygzhr13","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701","https://openalex.org/I4210138624"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Dong Si","raw_affiliation_strings":["University of Washington Bothell, Bothell, WA, USA"],"affiliations":[{"raw_affiliation_string":"University of Washington Bothell, Bothell, WA, USA","institution_ids":["https://openalex.org/I4210138624"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5080683855"],"corresponding_institution_ids":["https://openalex.org/I4210138624"],"apc_list":null,"apc_paid":null,"fwci":1.9662,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.94294138,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":null,"issue":null,"first_page":"156","last_page":"164"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10857","display_name":"Advanced Electron Microscopy Techniques and Applications","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10857","display_name":"Advanced Electron Microscopy Techniques and Applications","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10303","display_name":"Photosynthetic Processes and Mechanisms","score":0.9948999881744385,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/barrel","display_name":"Barrel (horology)","score":0.8131381273269653},{"id":"https://openalex.org/keywords/cryo-electron-microscopy","display_name":"Cryo-electron microscopy","score":0.8121117949485779},{"id":"https://openalex.org/keywords/resolution","display_name":"Resolution (logic)","score":0.7087619304656982},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.34314632415771484},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.31699687242507935},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.28435027599334717},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.21722659468650818},{"id":"https://openalex.org/keywords/nuclear-magnetic-resonance","display_name":"Nuclear magnetic resonance","score":0.12665829062461853}],"concepts":[{"id":"https://openalex.org/C172227984","wikidata":"https://www.wikidata.org/wiki/Q1400397","display_name":"Barrel (horology)","level":2,"score":0.8131381273269653},{"id":"https://openalex.org/C20702342","wikidata":"https://www.wikidata.org/wiki/Q5190506","display_name":"Cryo-electron microscopy","level":2,"score":0.8121117949485779},{"id":"https://openalex.org/C138268822","wikidata":"https://www.wikidata.org/wiki/Q1051925","display_name":"Resolution (logic)","level":2,"score":0.7087619304656982},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.34314632415771484},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.31699687242507935},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.28435027599334717},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.21722659468650818},{"id":"https://openalex.org/C46141821","wikidata":"https://www.wikidata.org/wiki/Q209402","display_name":"Nuclear magnetic resonance","level":1,"score":0.12665829062461853},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1145/2975167.2975183","is_oa":false,"landing_page_url":"https://doi.org/10.1145/2975167.2975183","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 7th ACM International Conference on Bioinformatics, Computational Biology, and Health Informatics","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W1558317748","https://openalex.org/W1810581179","https://openalex.org/W1965488238","https://openalex.org/W1966323820","https://openalex.org/W1975118489","https://openalex.org/W1986164502","https://openalex.org/W1987438054","https://openalex.org/W1994086483","https://openalex.org/W1995043996","https://openalex.org/W2004691211","https://openalex.org/W2006158980","https://openalex.org/W2009061886","https://openalex.org/W2018816581","https://openalex.org/W2024548552","https://openalex.org/W2037373017","https://openalex.org/W2043361746","https://openalex.org/W2046141572","https://openalex.org/W2046434485","https://openalex.org/W2048937426","https://openalex.org/W2053880783","https://openalex.org/W2054116168","https://openalex.org/W2059567258","https://openalex.org/W2061197399","https://openalex.org/W2061208873","https://openalex.org/W2076978930","https://openalex.org/W2084283552","https://openalex.org/W2085261163","https://openalex.org/W2088347357","https://openalex.org/W2089850706","https://openalex.org/W2096732301","https://openalex.org/W2109476464","https://openalex.org/W2110936528","https://openalex.org/W2132629607","https://openalex.org/W2137747821","https://openalex.org/W2147791333","https://openalex.org/W2152086886","https://openalex.org/W2155089380","https://openalex.org/W2165242943","https://openalex.org/W2165886631","https://openalex.org/W2167753573","https://openalex.org/W2169358216","https://openalex.org/W2233871097","https://openalex.org/W2275524693","https://openalex.org/W2293087217","https://openalex.org/W2523631673"],"related_works":["https://openalex.org/W2748952813","https://openalex.org/W2935759653","https://openalex.org/W3105167352","https://openalex.org/W54078636","https://openalex.org/W2791422888","https://openalex.org/W2949855111","https://openalex.org/W3006716706","https://openalex.org/W2991204057","https://openalex.org/W2617175248","https://openalex.org/W3036938294"],"abstract_inverted_index":{"Cryo-electron":[0],"microscopy":[1],"(Cryo-EM)":[2],"has":[3,14,66,123],"become":[4],"central":[5],"to":[6,48,79,104],"the":[7,84,107,116,153],"study":[8],"of":[9,90,95,120,155,163],"large-scale":[10],"molecular":[11],"interactions":[12],"and":[13,51,81,134,141],"produced":[15],"three-dimensional":[16],"(3D)":[17],"density":[18,31,54,91,112,129,161],"maps":[19,32,55,113,130,138,162],"at":[20,56,131],"various":[21],"resolutions.":[22],"Secondary":[23],"structure":[24,39,65],"element":[25],"(SSE)":[26],"identification":[27],"from":[28,53,92,110,157],"volumetric":[29],"protein":[30],"is":[33],"critical":[34],"for":[35,152],"de":[36],"novo":[37],"backbone":[38],"derivation":[40],"in":[41,69],"cryo-EM.":[42],"Multiple":[43],"methods":[44,77],"have":[45],"been":[46,67,124],"developed":[47],"detect":[49],"helix":[50],"\u03b2-sheet":[52,64],"medium":[57,158],"resolutions":[58],"(~5-10\u00c5).":[59],"\u03b2-barrel":[60,85,96,108,156,164],"as":[61,86],"a":[62,87],"special":[63],"found":[68],"many":[70],"proteins.":[71,165],"However,":[72],"currently":[73],"there":[74],"are":[75],"no":[76],"aimed":[78],"automatically":[80,105],"accurately":[82],"extract":[83,106],"complete":[88],"chunk":[89],"cryo-EM":[93,111,137,160],"map":[94],"protein.":[97],"We":[98],"present":[99],"an":[100],"effective":[101],"approach,":[102],"BarrelMiner,":[103],"region":[109],"based":[114],"on":[115],"conspicuous":[117],"cylindrical":[118],"shape":[119],"\u03b2-barrel.":[121],"BarrelMiner":[122,148],"tested":[125],"using":[126],"ten":[127],"simulated":[128],"10\u00c5":[132],"resolution":[133,159],"seven":[135],"experimental":[136],"between":[139],"5.5\u00c5":[140],"8.25\u00c5":[142],"resolution.":[143],"The":[144],"result":[145],"suggests":[146],"that":[147],"can":[149],"be":[150],"used":[151],"detection":[154]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}