{"id":"https://openalex.org/W2536068666","doi":"https://doi.org/10.1145/2966986.2967018","title":"Control-fluidic CoDesign for paper-based digital microfluidic biochips","display_name":"Control-fluidic CoDesign for paper-based digital microfluidic biochips","publication_year":2016,"publication_date":"2016-10-18","ids":{"openalex":"https://openalex.org/W2536068666","doi":"https://doi.org/10.1145/2966986.2967018","mag":"2536068666"},"language":"en","primary_location":{"id":"doi:10.1145/2966986.2967018","is_oa":false,"landing_page_url":"https://doi.org/10.1145/2966986.2967018","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 35th International Conference on Computer-Aided Design","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101498763","display_name":"Qin Wang","orcid":"https://orcid.org/0000-0003-2775-5502"},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Qin Wang","raw_affiliation_strings":["Tsinghua University","Department of Computer Science & Technology, Tsinghua University, China"],"affiliations":[{"raw_affiliation_string":"Tsinghua University","institution_ids":["https://openalex.org/I99065089"]},{"raw_affiliation_string":"Department of Computer Science & Technology, Tsinghua University, China","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085631655","display_name":"Zeyan Li","orcid":"https://orcid.org/0000-0002-3529-5879"},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zeyan Li","raw_affiliation_strings":["Tsinghua University","Department of Computer Science & Technology, Tsinghua University, China"],"affiliations":[{"raw_affiliation_string":"Tsinghua University","institution_ids":["https://openalex.org/I99065089"]},{"raw_affiliation_string":"Department of Computer Science & Technology, Tsinghua University, China","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014351062","display_name":"Haena Cheong","orcid":null},"institutions":[{"id":"https://openalex.org/I148751991","display_name":"Sogang University","ror":"https://ror.org/056tn4839","country_code":"KR","type":"education","lineage":["https://openalex.org/I148751991"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Haena Cheong","raw_affiliation_strings":["Sogang University","Department of Chemistry & Institute of Biological Interfaces, Sogang University, South Korea"],"affiliations":[{"raw_affiliation_string":"Sogang University","institution_ids":["https://openalex.org/I148751991"]},{"raw_affiliation_string":"Department of Chemistry & Institute of Biological Interfaces, Sogang University, South Korea","institution_ids":["https://openalex.org/I148751991"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020898359","display_name":"Oh\u2010Sun Kwon","orcid":"https://orcid.org/0000-0001-8605-8331"},"institutions":[{"id":"https://openalex.org/I148751991","display_name":"Sogang University","ror":"https://ror.org/056tn4839","country_code":"KR","type":"education","lineage":["https://openalex.org/I148751991"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Oh-Sun Kwon","raw_affiliation_strings":["Sogang University","Department of Chemistry & Institute of Biological Interfaces, Sogang University, South Korea"],"affiliations":[{"raw_affiliation_string":"Sogang University","institution_ids":["https://openalex.org/I148751991"]},{"raw_affiliation_string":"Department of Chemistry & Institute of Biological Interfaces, Sogang University, South Korea","institution_ids":["https://openalex.org/I148751991"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058812423","display_name":"Hailong Yao","orcid":"https://orcid.org/0000-0002-8750-3086"},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hailong Yao","raw_affiliation_strings":["Tsinghua University","Department of Computer Science & Technology, Tsinghua University, China"],"affiliations":[{"raw_affiliation_string":"Tsinghua University","institution_ids":["https://openalex.org/I99065089"]},{"raw_affiliation_string":"Department of Computer Science & Technology, Tsinghua University, China","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062800747","display_name":"Tsung-Yi Ho","orcid":"https://orcid.org/0000-0001-7348-5625"},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]},{"id":"https://openalex.org/I4210137766","display_name":"Institute for Advanced Study","ror":"https://ror.org/03xg85719","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210137766"]},{"id":"https://openalex.org/I25846049","display_name":"National Tsing Hua University","ror":"https://ror.org/00zdnkx70","country_code":"TW","type":"education","lineage":["https://openalex.org/I25846049"]}],"countries":["DE","TW"],"is_corresponding":false,"raw_author_name":"Tsung-Yi Ho","raw_affiliation_strings":["Technical University of Munich (TUM) and National Tsing Hua University","Institute for Advanced Study, Technical University of Munich (TUM), Germany"],"affiliations":[{"raw_affiliation_string":"Technical University of Munich (TUM) and National Tsing Hua University","institution_ids":["https://openalex.org/I25846049"]},{"raw_affiliation_string":"Institute for Advanced Study, Technical University of Munich (TUM), Germany","institution_ids":["https://openalex.org/I62916508","https://openalex.org/I4210137766"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034928816","display_name":"Kwanwoo Shin","orcid":"https://orcid.org/0000-0002-7563-8581"},"institutions":[{"id":"https://openalex.org/I148751991","display_name":"Sogang University","ror":"https://ror.org/056tn4839","country_code":"KR","type":"education","lineage":["https://openalex.org/I148751991"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Kwanwoo Shin","raw_affiliation_strings":["Sogang University","Department of Chemistry & Institute of Biological Interfaces, Sogang University, South Korea"],"affiliations":[{"raw_affiliation_string":"Sogang University","institution_ids":["https://openalex.org/I148751991"]},{"raw_affiliation_string":"Department of Chemistry & Institute of Biological Interfaces, Sogang University, South Korea","institution_ids":["https://openalex.org/I148751991"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100451231","display_name":"Bing Li","orcid":"https://orcid.org/0000-0001-9752-7201"},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Bing Li","raw_affiliation_strings":["Technical University of Munich (TUM)","Institute for Electronic Design Automation, Technical University of Munich (TUM), Germany"],"affiliations":[{"raw_affiliation_string":"Technical University of Munich (TUM)","institution_ids":["https://openalex.org/I62916508"]},{"raw_affiliation_string":"Institute for Electronic Design Automation, Technical University of Munich (TUM), Germany","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017567485","display_name":"Ulf Schlichtmann","orcid":"https://orcid.org/0000-0003-4431-7619"},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Ulf Schlichtmann","raw_affiliation_strings":["Technical University of Munich (TUM)","Institute for Electronic Design Automation, Technical University of Munich (TUM), Germany"],"affiliations":[{"raw_affiliation_string":"Technical University of Munich (TUM)","institution_ids":["https://openalex.org/I62916508"]},{"raw_affiliation_string":"Institute for Electronic Design Automation, Technical University of Munich (TUM), Germany","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111983610","display_name":"Yici Cai","orcid":null},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yici Cai","raw_affiliation_strings":["Tsinghua University","Department of Computer Science & Technology, Tsinghua University, China"],"affiliations":[{"raw_affiliation_string":"Tsinghua University","institution_ids":["https://openalex.org/I99065089"]},{"raw_affiliation_string":"Department of Computer Science & Technology, Tsinghua University, China","institution_ids":["https://openalex.org/I99065089"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":10,"corresponding_author_ids":["https://openalex.org/A5101498763"],"corresponding_institution_ids":["https://openalex.org/I99065089"],"apc_list":null,"apc_paid":null,"fwci":2.2052,"has_fulltext":false,"cited_by_count":29,"citation_normalized_percentile":{"value":0.88891774,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":98},"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"8"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12452","display_name":"Electrowetting and Microfluidic Technologies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12452","display_name":"Electrowetting and Microfluidic Technologies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11393","display_name":"Biosensors and Analytical Detection","score":0.9879999756813049,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12784","display_name":"Modular Robots and Swarm Intelligence","score":0.982200026512146,"subfield":{"id":"https://openalex.org/subfields/2210","display_name":"Mechanical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biochip","display_name":"Biochip","score":0.9556167125701904},{"id":"https://openalex.org/keywords/microfluidics","display_name":"Microfluidics","score":0.811881959438324},{"id":"https://openalex.org/keywords/fluidics","display_name":"Fluidics","score":0.7840307354927063},{"id":"https://openalex.org/keywords/digital-microfluidics","display_name":"Digital microfluidics","score":0.762721061706543},{"id":"https://openalex.org/keywords/routing","display_name":"Routing (electronic design automation)","score":0.6883107423782349},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.4493945240974426},{"id":"https://openalex.org/keywords/flow-control","display_name":"Flow control (data)","score":0.442465215921402},{"id":"https://openalex.org/keywords/scheduling","display_name":"Scheduling (production processes)","score":0.43260475993156433},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.3986862599849701},{"id":"https://openalex.org/keywords/voltage","display_name":"Voltage","score":0.38066092133522034},{"id":"https://openalex.org/keywords/electronic-engineering","display_name":"Electronic engineering","score":0.3791981339454651},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.37697136402130127},{"id":"https://openalex.org/keywords/embedded-system","display_name":"Embedded system","score":0.3658517599105835},{"id":"https://openalex.org/keywords/electrical-engineering","display_name":"Electrical engineering","score":0.18675497174263},{"id":"https://openalex.org/keywords/electrowetting","display_name":"Electrowetting","score":0.11478623747825623}],"concepts":[{"id":"https://openalex.org/C87892846","wikidata":"https://www.wikidata.org/wiki/Q864256","display_name":"Biochip","level":2,"score":0.9556167125701904},{"id":"https://openalex.org/C8673954","wikidata":"https://www.wikidata.org/wiki/Q138845","display_name":"Microfluidics","level":2,"score":0.811881959438324},{"id":"https://openalex.org/C132651336","wikidata":"https://www.wikidata.org/wiki/Q185571","display_name":"Fluidics","level":2,"score":0.7840307354927063},{"id":"https://openalex.org/C92444450","wikidata":"https://www.wikidata.org/wiki/Q5276112","display_name":"Digital microfluidics","level":4,"score":0.762721061706543},{"id":"https://openalex.org/C74172769","wikidata":"https://www.wikidata.org/wiki/Q1446839","display_name":"Routing (electronic design automation)","level":2,"score":0.6883107423782349},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.4493945240974426},{"id":"https://openalex.org/C186766456","wikidata":"https://www.wikidata.org/wiki/Q612457","display_name":"Flow control (data)","level":2,"score":0.442465215921402},{"id":"https://openalex.org/C206729178","wikidata":"https://www.wikidata.org/wiki/Q2271896","display_name":"Scheduling (production processes)","level":2,"score":0.43260475993156433},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.3986862599849701},{"id":"https://openalex.org/C165801399","wikidata":"https://www.wikidata.org/wiki/Q25428","display_name":"Voltage","level":2,"score":0.38066092133522034},{"id":"https://openalex.org/C24326235","wikidata":"https://www.wikidata.org/wiki/Q126095","display_name":"Electronic engineering","level":1,"score":0.3791981339454651},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.37697136402130127},{"id":"https://openalex.org/C149635348","wikidata":"https://www.wikidata.org/wiki/Q193040","display_name":"Embedded system","level":1,"score":0.3658517599105835},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.18675497174263},{"id":"https://openalex.org/C2779673822","wikidata":"https://www.wikidata.org/wiki/Q907239","display_name":"Electrowetting","level":3,"score":0.11478623747825623},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.0},{"id":"https://openalex.org/C21547014","wikidata":"https://www.wikidata.org/wiki/Q1423657","display_name":"Operations management","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1145/2966986.2967018","is_oa":false,"landing_page_url":"https://doi.org/10.1145/2966986.2967018","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 35th International Conference on Computer-Aided Design","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W1603428277","https://openalex.org/W1968000836","https://openalex.org/W1977545325","https://openalex.org/W1983989175","https://openalex.org/W2011283899","https://openalex.org/W2013470780","https://openalex.org/W2019560816","https://openalex.org/W2021257948","https://openalex.org/W2054559641","https://openalex.org/W2055666841","https://openalex.org/W2066225194","https://openalex.org/W2068561631","https://openalex.org/W2088342788","https://openalex.org/W2105755452","https://openalex.org/W2106616106","https://openalex.org/W2108056720","https://openalex.org/W2119985798","https://openalex.org/W2124470056","https://openalex.org/W2131779785","https://openalex.org/W2135474435","https://openalex.org/W2142581655","https://openalex.org/W2145026225","https://openalex.org/W2145106285","https://openalex.org/W2155143747","https://openalex.org/W2158818077","https://openalex.org/W2166910382","https://openalex.org/W2170862340","https://openalex.org/W2293702889","https://openalex.org/W4213060235"],"related_works":["https://openalex.org/W2593620286","https://openalex.org/W4235248979","https://openalex.org/W2624661525","https://openalex.org/W2791832251","https://openalex.org/W2105772751","https://openalex.org/W2757330072","https://openalex.org/W2738065864","https://openalex.org/W1834829329","https://openalex.org/W2074654211","https://openalex.org/W2332939083"],"abstract_inverted_index":{"Paper-based":[0],"digital":[1,45],"microfluidic":[2,46],"biochips":[3,47],"(P-DMFBs)":[4],"have":[5],"recently":[6],"emerged":[7],"as":[8,54],"a":[9,27,80,82,206],"promising":[10],"low-cost":[11],"and":[12,21,35,60,69,96,111,141,167],"fast-responsive":[13],"platform":[14],"for":[15,86],"biochemical":[16],"assays.":[17],"In":[18],"P-DMFBs,":[19,125],"electrodes":[20,68],"control":[22,71,101,138,152,171],"lines":[23,72],"are":[24,73],"printed":[25,74],"on":[26,75,99,170,191],"piece":[28],"of":[29,38,79,124,214],"photo":[30],"paper":[31,127],"using":[32],"inkjet":[33],"printer":[34,59],"conductive":[36],"ink":[37],"carbon":[39],"nanotubes":[40],"(CNTs).":[41],"Compared":[42],"with":[43,58,180],"traditional":[44],"(DMFBs),":[48],"P-DMFBs":[49],"enjoy":[50],"notable":[51],"advantages,":[52],"such":[53],"faster":[55],"in-place":[56],"fabrication":[57],"ink,":[61],"lower":[62],"costs,":[63],"better":[64],"disposability,":[65],"etc.":[66],"Because":[67],"CNT":[70,100],"the":[76,91,97,118,129,137,151,162,168,181,185,196,203,215],"same":[77],"side":[78],"paper,":[81],"new":[83,119],"design":[84,123],"challenge":[85],"P-DMFB":[87],"is":[88,175],"to":[89,145,159,177],"prevent":[90],"interference":[92],"between":[93,164],"moving":[94,165],"droplets":[95,166],"voltages":[98,169],"lines.":[102],"These":[103],"interactions":[104],"may":[105,155],"result":[106],"in":[107,121,184],"unexpected":[108],"droplet":[109,143,173],"movements":[110],"thus":[112],"incorrect":[113],"assay":[114],"outputs.":[115],"To":[116],"address":[117,160],"challenges":[120],"automated":[122],"this":[126],"proposes":[128],"first":[130],"control-fluidic":[131],"codesign":[132,198],"flow,":[133],"which":[134],"simultaneously":[135],"adjusts":[136],"line":[139,153],"routing":[140,154,186,209],"fluidic":[142],"scheduling":[144],"achieve":[146],"an":[147],"optimized":[148],"solution.":[149,187],"As":[150],"not":[156],"be":[157],"able":[158],"all":[161,202],"interferences":[163,183],"lines,":[172],"rescheduling":[174],"performed":[176],"effectively":[178],"deal":[179],"remaining":[182],"Computational":[188],"simulation":[189],"results":[190],"real-life":[192],"bioassays":[193],"show":[194],"that":[195],"proposed":[197],"method":[199,210],"successfully":[200],"eliminates":[201],"interferences,":[204],"while":[205],"state-of-the-art":[207],"maze":[208],"cannot":[211],"solve":[212],"any":[213],"benchmarks":[216],"without":[217],"conflicts.":[218]},"counts_by_year":[{"year":2024,"cited_by_count":3},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":4}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}