{"id":"https://openalex.org/W2055566037","doi":"https://doi.org/10.1145/2808719.2808744","title":"Unified tests for fine scale mapping and identifying sparse high-dimensional sequence associations","display_name":"Unified tests for fine scale mapping and identifying sparse high-dimensional sequence associations","publication_year":2015,"publication_date":"2015-09-09","ids":{"openalex":"https://openalex.org/W2055566037","doi":"https://doi.org/10.1145/2808719.2808744","mag":"2055566037"},"language":"en","primary_location":{"id":"doi:10.1145/2808719.2808744","is_oa":false,"landing_page_url":"https://doi.org/10.1145/2808719.2808744","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 6th ACM Conference on Bioinformatics, Computational Biology and Health Informatics","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050558613","display_name":"Shaolong Cao","orcid":"https://orcid.org/0000-0002-4443-9424"},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Shaolong Cao","raw_affiliation_strings":["Tulane University, New Orleans, LA"],"affiliations":[{"raw_affiliation_string":"Tulane University, New Orleans, LA","institution_ids":["https://openalex.org/I114832834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083380474","display_name":"Huaizhen Qin","orcid":"https://orcid.org/0000-0002-3583-7383"},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Huaizhen Qin","raw_affiliation_strings":["Tulane University, New Orleans, LA"],"affiliations":[{"raw_affiliation_string":"Tulane University, New Orleans, LA","institution_ids":["https://openalex.org/I114832834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091213912","display_name":"Alexej Gossmann","orcid":"https://orcid.org/0000-0001-9068-3877"},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alexej Gossmann","raw_affiliation_strings":["Tulane University, New Orleans, LA"],"affiliations":[{"raw_affiliation_string":"Tulane University, New Orleans, LA","institution_ids":["https://openalex.org/I114832834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024194480","display_name":"Hong\u2010Wen Deng","orcid":"https://orcid.org/0000-0002-0387-8818"},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hong-Wen Deng","raw_affiliation_strings":["Tulane University, New Orleans, LA"],"affiliations":[{"raw_affiliation_string":"Tulane University, New Orleans, LA","institution_ids":["https://openalex.org/I114832834"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100339106","display_name":"Yu\u2010Ping Wang","orcid":"https://orcid.org/0000-0001-9340-5864"},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yu-Ping Wang","raw_affiliation_strings":["Tulane University, New Orleans, LA"],"affiliations":[{"raw_affiliation_string":"Tulane University, New Orleans, LA","institution_ids":["https://openalex.org/I114832834"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5050558613"],"corresponding_institution_ids":["https://openalex.org/I114832834"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.05354951,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"241","last_page":"249"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9836000204086304,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10594","display_name":"Genetic and phenotypic traits in livestock","score":0.9819999933242798,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.6247072219848633},{"id":"https://openalex.org/keywords/sequence","display_name":"Sequence (biology)","score":0.5197781920433044},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5127597451210022},{"id":"https://openalex.org/keywords/genetic-association","display_name":"Genetic association","score":0.49981093406677246},{"id":"https://openalex.org/keywords/set","display_name":"Set (abstract data type)","score":0.4943959712982178},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.48330023884773254},{"id":"https://openalex.org/keywords/snp","display_name":"SNP","score":0.4711821377277374},{"id":"https://openalex.org/keywords/evolutionary-biology","display_name":"Evolutionary biology","score":0.45309191942214966},{"id":"https://openalex.org/keywords/association","display_name":"Association (psychology)","score":0.4372675120830536},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.37476545572280884},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3446519374847412},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.327783465385437},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphism","display_name":"Single-nucleotide polymorphism","score":0.274745911359787},{"id":"https://openalex.org/keywords/genotype","display_name":"Genotype","score":0.13880854845046997},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.08806675672531128},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.06841591000556946}],"concepts":[{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.6247072219848633},{"id":"https://openalex.org/C2778112365","wikidata":"https://www.wikidata.org/wiki/Q3511065","display_name":"Sequence (biology)","level":2,"score":0.5197781920433044},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5127597451210022},{"id":"https://openalex.org/C186413461","wikidata":"https://www.wikidata.org/wiki/Q744727","display_name":"Genetic association","level":5,"score":0.49981093406677246},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.4943959712982178},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.48330023884773254},{"id":"https://openalex.org/C139275648","wikidata":"https://www.wikidata.org/wiki/Q17134011","display_name":"SNP","level":5,"score":0.4711821377277374},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.45309191942214966},{"id":"https://openalex.org/C142853389","wikidata":"https://www.wikidata.org/wiki/Q744778","display_name":"Association (psychology)","level":2,"score":0.4372675120830536},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.37476545572280884},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3446519374847412},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.327783465385437},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.274745911359787},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.13880854845046997},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.08806675672531128},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.06841591000556946},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0},{"id":"https://openalex.org/C542102704","wikidata":"https://www.wikidata.org/wiki/Q183257","display_name":"Psychotherapist","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1145/2808719.2808744","is_oa":false,"landing_page_url":"https://doi.org/10.1145/2808719.2808744","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 6th ACM Conference on Bioinformatics, Computational Biology and Health Informatics","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W1502908645","https://openalex.org/W1952660301","https://openalex.org/W1973397215","https://openalex.org/W1976587387","https://openalex.org/W1980168725","https://openalex.org/W1981403760","https://openalex.org/W2003472145","https://openalex.org/W2012158163","https://openalex.org/W2019309231","https://openalex.org/W2047028564","https://openalex.org/W2051864124","https://openalex.org/W2086159554","https://openalex.org/W2091242584","https://openalex.org/W2097209031","https://openalex.org/W2110065044","https://openalex.org/W2112004596","https://openalex.org/W2116190639","https://openalex.org/W2122825543","https://openalex.org/W2128235479","https://openalex.org/W2135046866","https://openalex.org/W2143079975","https://openalex.org/W2154972590","https://openalex.org/W2163953557","https://openalex.org/W2221775387","https://openalex.org/W2562162676","https://openalex.org/W2987011813","https://openalex.org/W3106369002","https://openalex.org/W4246629400"],"related_works":["https://openalex.org/W2352440174","https://openalex.org/W4309440960","https://openalex.org/W3026696341","https://openalex.org/W4226065002","https://openalex.org/W2774988270","https://openalex.org/W1601337698","https://openalex.org/W3132297604","https://openalex.org/W1587862541","https://openalex.org/W2602215520","https://openalex.org/W1987313132"],"abstract_inverted_index":{"Joint":[0],"adjustment":[1],"of":[2,14,27,40,51,78,89],"complex":[3],"or":[4,83],"cryptic":[5,30],"relatedness":[6,31],"can":[7],"help":[8],"to":[9,66,85],"greatly":[10],"improve":[11],"the":[12,37,90],"identification":[13,50],"rare":[15],"and":[16,32],"common":[17],"genetic":[18],"variants":[19,53,69],"for":[20,49],"quantitative":[21],"traits.":[22],"In":[23],"deep":[24],"sequencing":[25],"studies":[26],"admixed":[28],"individuals,":[29],"population":[33],"structure":[34],"notoriously":[35],"confound":[36],"association":[38,45],"analyses":[39],"high-dimensional":[41,71],"marker":[42],"sets.":[43],"Existing":[44],"tests":[46],"are":[47],"powerful":[48],"functional":[52],"in":[54,70],"large":[55],"samples":[56],"with":[57],"random":[58],"relatedness.":[59],"These":[60],"tests,":[61],"however,":[62],"have":[63],"low":[64],"power":[65],"identify":[67],"susceptible":[68],"SNP":[72,91],"sets,":[73],"where":[74],"n":[75],"(the":[76,87],"number":[77],"observations)":[79],"is":[80],"smaller":[81],"than":[82],"close":[84],"m":[86],"size":[88],"set":[92],"under":[93],"testing).":[94]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}