{"id":"https://openalex.org/W2029033363","doi":"https://doi.org/10.1145/2667231","title":"Formalizing Modularization and Data Hiding in Synthetic Biology","display_name":"Formalizing Modularization and Data Hiding in Synthetic Biology","publication_year":2014,"publication_date":"2014-12-30","ids":{"openalex":"https://openalex.org/W2029033363","doi":"https://doi.org/10.1145/2667231","mag":"2029033363"},"language":"en","primary_location":{"id":"doi:10.1145/2667231","is_oa":false,"landing_page_url":"https://doi.org/10.1145/2667231","pdf_url":null,"source":{"id":"https://openalex.org/S96198239","display_name":"ACM Journal on Emerging Technologies in Computing Systems","issn_l":"1550-4832","issn":["1550-4832","1550-4840"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319798","host_organization_name":"Association for Computing Machinery","host_organization_lineage":["https://openalex.org/P4310319798"],"host_organization_lineage_names":["Association for Computing Machinery"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ACM Journal on Emerging Technologies in Computing Systems","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://hdl.handle.net/11475/2712","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055847229","display_name":"Harold Fellermann","orcid":"https://orcid.org/0000-0001-5861-1945"},"institutions":[{"id":"https://openalex.org/I84884186","display_name":"Newcastle University","ror":"https://ror.org/01kj2bm70","country_code":"GB","type":"education","lineage":["https://openalex.org/I84884186"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Harold Fellermann","raw_affiliation_strings":["Newcastle University, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Newcastle University, United Kingdom","institution_ids":["https://openalex.org/I84884186"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072112257","display_name":"Maik Hadorn","orcid":"https://orcid.org/0000-0003-4530-9346"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Maik Hadorn","raw_affiliation_strings":["Swiss Federal Institute of Technology, Zurich, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Swiss Federal Institute of Technology, Zurich, Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003398081","display_name":"Rudolf Marcel F\u00fcchslin","orcid":"https://orcid.org/0000-0002-9296-5314"},"institutions":[{"id":"https://openalex.org/I858936495","display_name":"ZHAW Zurich University of Applied Sciences","ror":"https://ror.org/05pmsvm27","country_code":"CH","type":"education","lineage":["https://openalex.org/I858936495"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Rudolf M. F\u00fcchslin","raw_affiliation_strings":["Zurich University of Applied Sciences, Winterthur, Switzerland","[Zurich University of Applied Sciences, Winterthur, Switzerland]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Zurich University of Applied Sciences, Winterthur, Switzerland","institution_ids":["https://openalex.org/I858936495"]},{"raw_affiliation_string":"[Zurich University of Applied Sciences, Winterthur, Switzerland]","institution_ids":["https://openalex.org/I858936495"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043620976","display_name":"Natalio Krasnogor","orcid":"https://orcid.org/0000-0002-2651-4320"},"institutions":[{"id":"https://openalex.org/I84884186","display_name":"Newcastle University","ror":"https://ror.org/01kj2bm70","country_code":"GB","type":"education","lineage":["https://openalex.org/I84884186"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Natalio Krasnogor","raw_affiliation_strings":["Newcastle University, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Newcastle University, United Kingdom","institution_ids":["https://openalex.org/I84884186"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.1423,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.53807624,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":95},"biblio":{"volume":"11","issue":"3","first_page":"1","last_page":"20"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12029","display_name":"DNA and Biological Computing","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12029","display_name":"DNA and Biological Computing","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10911","display_name":"Chemical Synthesis and Analysis","score":0.9684000015258789,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/synthetic-biology","display_name":"Synthetic biology","score":0.790187418460846},{"id":"https://openalex.org/keywords/modular-programming","display_name":"Modular programming","score":0.7730544209480286},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6808496117591858},{"id":"https://openalex.org/keywords/compartmentalization","display_name":"Compartmentalization (fire protection)","score":0.6253514289855957},{"id":"https://openalex.org/keywords/sbml","display_name":"SBML","score":0.49028757214546204},{"id":"https://openalex.org/keywords/protocell","display_name":"Protocell","score":0.44467073678970337},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.4119933545589447},{"id":"https://openalex.org/keywords/computer-architecture","display_name":"Computer architecture","score":0.33048978447914124},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.2666734755039215},{"id":"https://openalex.org/keywords/markup-language","display_name":"Markup language","score":0.16869184374809265},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.1301223337650299},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.12633869051933289},{"id":"https://openalex.org/keywords/xml","display_name":"XML","score":0.10753130912780762}],"concepts":[{"id":"https://openalex.org/C191908910","wikidata":"https://www.wikidata.org/wiki/Q862838","display_name":"Synthetic biology","level":2,"score":0.790187418460846},{"id":"https://openalex.org/C88482812","wikidata":"https://www.wikidata.org/wiki/Q6453666","display_name":"Modular programming","level":2,"score":0.7730544209480286},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6808496117591858},{"id":"https://openalex.org/C110455231","wikidata":"https://www.wikidata.org/wiki/Q897788","display_name":"Compartmentalization (fire protection)","level":3,"score":0.6253514289855957},{"id":"https://openalex.org/C87186988","wikidata":"https://www.wikidata.org/wiki/Q452197","display_name":"SBML","level":4,"score":0.49028757214546204},{"id":"https://openalex.org/C114032466","wikidata":"https://www.wikidata.org/wiki/Q1389465","display_name":"Protocell","level":3,"score":0.44467073678970337},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.4119933545589447},{"id":"https://openalex.org/C118524514","wikidata":"https://www.wikidata.org/wiki/Q173212","display_name":"Computer architecture","level":1,"score":0.33048978447914124},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.2666734755039215},{"id":"https://openalex.org/C45874996","wikidata":"https://www.wikidata.org/wiki/Q37045","display_name":"Markup language","level":3,"score":0.16869184374809265},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.1301223337650299},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.12633869051933289},{"id":"https://openalex.org/C8797682","wikidata":"https://www.wikidata.org/wiki/Q2115","display_name":"XML","level":2,"score":0.10753130912780762},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.0},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1145/2667231","is_oa":false,"landing_page_url":"https://doi.org/10.1145/2667231","pdf_url":null,"source":{"id":"https://openalex.org/S96198239","display_name":"ACM Journal on Emerging Technologies in Computing Systems","issn_l":"1550-4832","issn":["1550-4832","1550-4840"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319798","host_organization_name":"Association for Computing Machinery","host_organization_lineage":["https://openalex.org/P4310319798"],"host_organization_lineage_names":["Association for Computing Machinery"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ACM Journal on Emerging Technologies in Computing Systems","raw_type":"journal-article"},{"id":"pmh:oai:digitalcollection.zhaw.ch:11475/2712","is_oa":true,"landing_page_url":"https://hdl.handle.net/11475/2712","pdf_url":null,"source":{"id":"https://openalex.org/S4306401810","display_name":"Z\u00fcrcher Hochschule f\u00fcr Angewandte Wissenschaften digital collection (Zurich University of Applied Sciences)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I200744771","host_organization_name":"ZHAW Zurich University of Applied Sciences","host_organization_lineage":["https://openalex.org/I200744771"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"doi:10.21256/zhaw-1657","is_oa":true,"landing_page_url":"https://doi.org/10.21256/zhaw-1657","pdf_url":null,"source":{"id":"https://openalex.org/S7407051289","display_name":"ZHAW Digital Collection","issn_l":null,"issn":[],"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"pmh:oai:digitalcollection.zhaw.ch:11475/2712","is_oa":true,"landing_page_url":"https://hdl.handle.net/11475/2712","pdf_url":null,"source":{"id":"https://openalex.org/S4306401810","display_name":"Z\u00fcrcher Hochschule f\u00fcr Angewandte Wissenschaften digital collection (Zurich University of Applied Sciences)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I200744771","host_organization_name":"ZHAW Zurich University of Applied Sciences","host_organization_lineage":["https://openalex.org/I200744771"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G2975747758","display_name":null,"funder_award_id":"EP/I031642/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G502459198","display_name":null,"funder_award_id":"EP/I031642/2","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G5140230474","display_name":null,"funder_award_id":"EP/J004111/2","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G6253955250","display_name":null,"funder_award_id":"EP/L001489/2","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G8767074128","display_name":null,"funder_award_id":"EP/J004111/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320334627","display_name":"Engineering and Physical Sciences Research Council","ror":"https://ror.org/0439y7842"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":87,"referenced_works":["https://openalex.org/W398424092","https://openalex.org/W1567090568","https://openalex.org/W1963573377","https://openalex.org/W1965710067","https://openalex.org/W1966101773","https://openalex.org/W1967139808","https://openalex.org/W1968023156","https://openalex.org/W1970221707","https://openalex.org/W1972228705","https://openalex.org/W1974602807","https://openalex.org/W1976440785","https://openalex.org/W1977403354","https://openalex.org/W1978051396","https://openalex.org/W1978881658","https://openalex.org/W1981051260","https://openalex.org/W1981897381","https://openalex.org/W1984586189","https://openalex.org/W1984954149","https://openalex.org/W1985357096","https://openalex.org/W1987210689","https://openalex.org/W1987819161","https://openalex.org/W1988104419","https://openalex.org/W1990476699","https://openalex.org/W1993891907","https://openalex.org/W2003327062","https://openalex.org/W2009421164","https://openalex.org/W2013141063","https://openalex.org/W2015930349","https://openalex.org/W2016266703","https://openalex.org/W2018048505","https://openalex.org/W2021385113","https://openalex.org/W2023525048","https://openalex.org/W2024992445","https://openalex.org/W2027576577","https://openalex.org/W2029964904","https://openalex.org/W2041857964","https://openalex.org/W2042939769","https://openalex.org/W2046617873","https://openalex.org/W2047231556","https://openalex.org/W2048693579","https://openalex.org/W2051953600","https://openalex.org/W2052387983","https://openalex.org/W2052566608","https://openalex.org/W2052731133","https://openalex.org/W2060708192","https://openalex.org/W2061510929","https://openalex.org/W2067007508","https://openalex.org/W2071242556","https://openalex.org/W2075031841","https://openalex.org/W2076607216","https://openalex.org/W2078585625","https://openalex.org/W2080727511","https://openalex.org/W2083281506","https://openalex.org/W2093275839","https://openalex.org/W2101044126","https://openalex.org/W2103256803","https://openalex.org/W2104808978","https://openalex.org/W2113214821","https://openalex.org/W2116110734","https://openalex.org/W2116343004","https://openalex.org/W2120301307","https://openalex.org/W2122261310","https://openalex.org/W2126961173","https://openalex.org/W2129232972","https://openalex.org/W2129955018","https://openalex.org/W2133772902","https://openalex.org/W2138018894","https://openalex.org/W2139768072","https://openalex.org/W2144129306","https://openalex.org/W2146062744","https://openalex.org/W2149181149","https://openalex.org/W2149590872","https://openalex.org/W2150109115","https://openalex.org/W2153349989","https://openalex.org/W2154676639","https://openalex.org/W2158313010","https://openalex.org/W2158708642","https://openalex.org/W2160965183","https://openalex.org/W2162586071","https://openalex.org/W2163413204","https://openalex.org/W2167192225","https://openalex.org/W2172114355","https://openalex.org/W2230370122","https://openalex.org/W2324367015","https://openalex.org/W2913004508","https://openalex.org/W4256503849","https://openalex.org/W6663435272"],"related_works":["https://openalex.org/W2007951194","https://openalex.org/W4200430658","https://openalex.org/W2089441778","https://openalex.org/W2160381296","https://openalex.org/W4313178915","https://openalex.org/W2211443823","https://openalex.org/W2144129306","https://openalex.org/W1986597369","https://openalex.org/W1981444142","https://openalex.org/W4221053143"],"abstract_inverted_index":{"Biological":[0],"systems":[1],"employ":[2],"compartmentalization":[3,31,106],"and":[4,22,32,42,50,63,76,88,90,117],"other":[5],"co-localization":[6],"strategies":[7],"in":[8,39],"order":[9],"to":[10,113],"orchestrate":[11],"a":[12],"multitude":[13],"of":[14,95,124],"biochemical":[15,61],"processes":[16],"by":[17],"simultaneously":[18],"enabling":[19,92],"\u201cdata":[20],"hiding\u201d":[21],"modularization.":[23],"This":[24],"article":[25],"presents":[26],"recent":[27],"research":[28],"that":[29],"embraces":[30],"co-location":[33],"as":[34,56,64,82],"an":[35],"organizational":[36],"programmatic":[37],"principle":[38],"synthetic":[40,51],"biological":[41],"biomimetic":[43],"systems.":[44,102],"In":[45],"these":[46],"systems,":[47,73],"artificial":[48],"vesicles":[49],"minimal":[52],"cells":[53],"are":[54],"envisioned":[55],"nanoscale":[57],"reactors":[58],"for":[59,66],"programmable":[60,125],"synthesis":[62],"chassis":[65],"molecular":[67],"information":[68],"processing.":[69],"We":[70,103],"present":[71],"P":[72],"brane":[74],"calculi,":[75],"the":[77,93,110,122],"recently":[78],"developed":[79],"chemtainer":[80],"calculus":[81],"formal":[83],"frameworks":[84],"providing":[85],"data":[86],"hiding":[87],"modularization":[89],"thus":[91],"representation":[94],"highly":[96],"complicated":[97],"hierarchically":[98],"organized":[99],"compartmentalized":[100],"reaction":[101],"demonstrate":[104],"how":[105,118],"can":[107],"greatly":[108],"reduce":[109],"complexity":[111],"required":[112],"implement":[114],"computational":[115],"functionality,":[116],"addressable":[119],"compartments":[120],"permit":[121],"scaling-up":[123],"chemical":[126],"synthesis.":[127]},"counts_by_year":[{"year":2021,"cited_by_count":2},{"year":2016,"cited_by_count":1}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}
