{"id":"https://openalex.org/W1993204835","doi":"https://doi.org/10.1145/2382936.2383027","title":"Predicting possible directed-graph patterns of gene expressions in studies involving multiple treatments","display_name":"Predicting possible directed-graph patterns of gene expressions in studies involving multiple treatments","publication_year":2012,"publication_date":"2012-10-07","ids":{"openalex":"https://openalex.org/W1993204835","doi":"https://doi.org/10.1145/2382936.2383027","mag":"1993204835"},"language":"en","primary_location":{"id":"doi:10.1145/2382936.2383027","is_oa":false,"landing_page_url":"https://doi.org/10.1145/2382936.2383027","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the ACM Conference on Bioinformatics, Computational Biology and Biomedicine","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043745628","display_name":"Nam S. Vo","orcid":"https://orcid.org/0000-0002-5454-9176"},"institutions":[{"id":"https://openalex.org/I94658018","display_name":"University of Memphis","ror":"https://ror.org/01cq23130","country_code":"US","type":"education","lineage":["https://openalex.org/I94658018"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nam S. Vo","raw_affiliation_strings":["The University of Memphis, Memphis, TN","The University of Memphis , Memphis, TN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The University of Memphis, Memphis, TN","institution_ids":["https://openalex.org/I94658018"]},{"raw_affiliation_string":"The University of Memphis , Memphis, TN","institution_ids":["https://openalex.org/I94658018"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019979430","display_name":"Vinhthuy Phan","orcid":"https://orcid.org/0000-0001-6108-1228"},"institutions":[{"id":"https://openalex.org/I94658018","display_name":"University of Memphis","ror":"https://ror.org/01cq23130","country_code":"US","type":"education","lineage":["https://openalex.org/I94658018"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vinhthuy Phan","raw_affiliation_strings":["The University of Memphis, Memphis, TN","The University of Memphis , Memphis, TN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The University of Memphis, Memphis, TN","institution_ids":["https://openalex.org/I94658018"]},{"raw_affiliation_string":"The University of Memphis , Memphis, TN","institution_ids":["https://openalex.org/I94658018"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058407840","display_name":"Thomas R. Sutter","orcid":"https://orcid.org/0000-0002-6088-6320"},"institutions":[{"id":"https://openalex.org/I94658018","display_name":"University of Memphis","ror":"https://ror.org/01cq23130","country_code":"US","type":"education","lineage":["https://openalex.org/I94658018"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas R. Sutter","raw_affiliation_strings":["The University of Memphis, Memphis, TN","The University of Memphis , Memphis, TN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The University of Memphis, Memphis, TN","institution_ids":["https://openalex.org/I94658018"]},{"raw_affiliation_string":"The University of Memphis , Memphis, TN","institution_ids":["https://openalex.org/I94658018"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I94658018"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.06725603,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"579","last_page":"581"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11970","display_name":"Molecular Biology Techniques and Applications","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.5331318378448486},{"id":"https://openalex.org/keywords/graph","display_name":"Graph","score":0.5216772556304932},{"id":"https://openalex.org/keywords/sample-size-determination","display_name":"Sample size determination","score":0.5106704831123352},{"id":"https://openalex.org/keywords/exploit","display_name":"Exploit","score":0.49895644187927246},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4674312472343445},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.4254814386367798},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.42515113949775696},{"id":"https://openalex.org/keywords/sample","display_name":"Sample (material)","score":0.4107967019081116},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3678644299507141},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.32936644554138184},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.2908482551574707},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.2104441523551941},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.1995874047279358}],"concepts":[{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.5331318378448486},{"id":"https://openalex.org/C132525143","wikidata":"https://www.wikidata.org/wiki/Q141488","display_name":"Graph","level":2,"score":0.5216772556304932},{"id":"https://openalex.org/C129848803","wikidata":"https://www.wikidata.org/wiki/Q2564360","display_name":"Sample size determination","level":2,"score":0.5106704831123352},{"id":"https://openalex.org/C165696696","wikidata":"https://www.wikidata.org/wiki/Q11287","display_name":"Exploit","level":2,"score":0.49895644187927246},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4674312472343445},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4254814386367798},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.42515113949775696},{"id":"https://openalex.org/C198531522","wikidata":"https://www.wikidata.org/wiki/Q485146","display_name":"Sample (material)","level":2,"score":0.4107967019081116},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3678644299507141},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.32936644554138184},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2908482551574707},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.2104441523551941},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.1995874047279358},{"id":"https://openalex.org/C38652104","wikidata":"https://www.wikidata.org/wiki/Q3510521","display_name":"Computer security","level":1,"score":0.0},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1145/2382936.2383027","is_oa":false,"landing_page_url":"https://doi.org/10.1145/2382936.2383027","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the ACM Conference on Bioinformatics, Computational Biology and Biomedicine","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":6,"referenced_works":["https://openalex.org/W2021429824","https://openalex.org/W2041208925","https://openalex.org/W2065912508","https://openalex.org/W2097860373","https://openalex.org/W2097917417","https://openalex.org/W2156674292"],"related_works":["https://openalex.org/W4388813866","https://openalex.org/W2999104021","https://openalex.org/W1481656249","https://openalex.org/W2850804095","https://openalex.org/W2162280767","https://openalex.org/W3047225376","https://openalex.org/W1570799877","https://openalex.org/W2800688113","https://openalex.org/W4236933217","https://openalex.org/W2057598446"],"abstract_inverted_index":{"Analysis":[0],"of":[1,10,23,30,62],"gene":[2,11,32,63],"expression":[3,12,33],"data":[4],"from":[5,69],"studies":[6],"to":[7,13,20,35,59,72],"assess":[8],"patterns":[9,61,76],"multiple":[14,36],"treatments":[15,37],"is":[16],"usually":[17],"challenging":[18],"due":[19],"the":[21],"inadequacy":[22],"sample":[24,46],"size.":[25],"We":[26,55],"introduce":[27],"an":[28],"approach":[29],"representing":[31],"response":[34,64],"using":[38,65],"directed":[39],"graphs":[40],"and":[41,48],"establish":[42],"a":[43,49],"relationship":[44,58],"between":[45],"size":[47],"graph":[50],"property":[51],"known":[52],"as":[53],"contractibility.":[54],"exploit":[56],"this":[57],"predict":[60],"synthetic":[66],"replicates":[67],"generated":[68],"real":[70],"samples":[71],"produce":[73],"most":[74],"probable":[75],"for":[77],"each":[78],"pattern":[79],"observed":[80],"based":[81],"on":[82],"experimental":[83],"replicates.":[84]},"counts_by_year":[],"updated_date":"2026-06-26T08:34:08.712188","created_date":"2025-10-10T00:00:00"}