{"id":"https://openalex.org/W1988117960","doi":"https://doi.org/10.1145/2382936.2383018","title":"Classification of multicolor fluorescence <i>in-situ</i> hybridization (M-FISH) image using regularized multinomial logistic regression","display_name":"Classification of multicolor fluorescence <i>in-situ</i> hybridization (M-FISH) image using regularized multinomial logistic regression","publication_year":2012,"publication_date":"2012-10-07","ids":{"openalex":"https://openalex.org/W1988117960","doi":"https://doi.org/10.1145/2382936.2383018","mag":"1988117960"},"language":"en","primary_location":{"id":"doi:10.1145/2382936.2383018","is_oa":false,"landing_page_url":"https://doi.org/10.1145/2382936.2383018","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the ACM Conference on Bioinformatics, Computational Biology and Biomedicine","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100739865","display_name":"Jingyao Li","orcid":"https://orcid.org/0000-0003-1498-5501"},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jingyao Li","raw_affiliation_strings":["Tulane University, New Orleans, LA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tulane University, New Orleans, LA","institution_ids":["https://openalex.org/I114832834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079946688","display_name":"Hongbao Cao","orcid":"https://orcid.org/0000-0001-6591-9518"},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hongbao Cao","raw_affiliation_strings":["Tulane University, New Orleans, LA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tulane University, New Orleans, LA","institution_ids":["https://openalex.org/I114832834"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100339108","display_name":"Yu-Ping Wang","orcid":"https://orcid.org/0000-0002-2822-5813"},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yu-Ping Wang","raw_affiliation_strings":["Tulane University, New Orleans, LA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tulane University, New Orleans, LA","institution_ids":["https://openalex.org/I114832834"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.07971742,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"551","last_page":"554"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11213","display_name":"Genomic variations and chromosomal abnormalities","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11213","display_name":"Genomic variations and chromosomal abnormalities","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9973000288009644,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.9904999732971191,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/multinomial-logistic-regression","display_name":"Multinomial logistic regression","score":0.9340839385986328},{"id":"https://openalex.org/keywords/logistic-regression","display_name":"Logistic regression","score":0.6957240104675293},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.6675376296043396},{"id":"https://openalex.org/keywords/fish-actinopterygii","display_name":"Fish <Actinopterygii>","score":0.6120203137397766},{"id":"https://openalex.org/keywords/multinomial-distribution","display_name":"Multinomial distribution","score":0.6096583008766174},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5390097498893738},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.5302942395210266},{"id":"https://openalex.org/keywords/regression","display_name":"Regression","score":0.5088942050933838},{"id":"https://openalex.org/keywords/fluorescence-in-situ-hybridization","display_name":"Fluorescence in situ hybridization","score":0.5028769373893738},{"id":"https://openalex.org/keywords/regression-analysis","display_name":"Regression analysis","score":0.44078588485717773},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4388899505138397},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.43273162841796875},{"id":"https://openalex.org/keywords/contextual-image-classification","display_name":"Contextual image classification","score":0.41284799575805664},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.4116198420524597},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.19840779900550842},{"id":"https://openalex.org/keywords/fishery","display_name":"Fishery","score":0.12852227687835693},{"id":"https://openalex.org/keywords/chromosome","display_name":"Chromosome","score":0.07010471820831299},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.06125566363334656}],"concepts":[{"id":"https://openalex.org/C117568660","wikidata":"https://www.wikidata.org/wiki/Q1650843","display_name":"Multinomial logistic regression","level":2,"score":0.9340839385986328},{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.6957240104675293},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.6675376296043396},{"id":"https://openalex.org/C2909208804","wikidata":"https://www.wikidata.org/wiki/Q127282","display_name":"Fish <Actinopterygii>","level":2,"score":0.6120203137397766},{"id":"https://openalex.org/C192065140","wikidata":"https://www.wikidata.org/wiki/Q1147928","display_name":"Multinomial distribution","level":2,"score":0.6096583008766174},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5390097498893738},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.5302942395210266},{"id":"https://openalex.org/C83546350","wikidata":"https://www.wikidata.org/wiki/Q1139051","display_name":"Regression","level":2,"score":0.5088942050933838},{"id":"https://openalex.org/C2777542201","wikidata":"https://www.wikidata.org/wiki/Q1336182","display_name":"Fluorescence in situ hybridization","level":4,"score":0.5028769373893738},{"id":"https://openalex.org/C152877465","wikidata":"https://www.wikidata.org/wiki/Q208042","display_name":"Regression analysis","level":2,"score":0.44078588485717773},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4388899505138397},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.43273162841796875},{"id":"https://openalex.org/C75294576","wikidata":"https://www.wikidata.org/wiki/Q5165192","display_name":"Contextual image classification","level":3,"score":0.41284799575805664},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.4116198420524597},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.19840779900550842},{"id":"https://openalex.org/C505870484","wikidata":"https://www.wikidata.org/wiki/Q180538","display_name":"Fishery","level":1,"score":0.12852227687835693},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.07010471820831299},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.06125566363334656},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1145/2382936.2383018","is_oa":false,"landing_page_url":"https://doi.org/10.1145/2382936.2383018","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the ACM Conference on Bioinformatics, Computational Biology and Biomedicine","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/14","display_name":"Life below water","score":0.49000000953674316}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":8,"referenced_works":["https://openalex.org/W1984845482","https://openalex.org/W1985089773","https://openalex.org/W2037479635","https://openalex.org/W2075261942","https://openalex.org/W2088859281","https://openalex.org/W2100518076","https://openalex.org/W2140356950","https://openalex.org/W2150579376"],"related_works":["https://openalex.org/W2494119046","https://openalex.org/W2955220190","https://openalex.org/W1506113033","https://openalex.org/W2369306031","https://openalex.org/W2052791731","https://openalex.org/W4320168697","https://openalex.org/W3098841390","https://openalex.org/W2784774275","https://openalex.org/W2184978910","https://openalex.org/W1917858188"],"abstract_inverted_index":{"In":[0],"this":[1],"paper,":[2],"we":[3,101],"applied":[4],"a":[5,95],"regularized":[6],"multinomial":[7,54,60],"logistic":[8,55,61],"regression":[9,51,56,62],"(RMLR)":[10],"for":[11],"multicolor":[12],"fluorescence":[13],"in-situ":[14],"hybridization":[15],"(M-FISH)":[16],"image":[17,98,122],"analysis,":[18],"in":[19,94],"order":[20],"to":[21],"better":[22],"classify":[23],"chromosomes.":[24],"The":[25],"RMLR":[26,76,113],"integrates":[27],"complementary":[28],"information":[29],"from":[30],"multi-channel":[31],"M-FISH":[32,97,121],"images":[33],"and":[34,58,84,89,103],"considers":[35],"the":[36,46,67,75,87,104,112,118],"relationship":[37],"of":[38,71,106,120],"these":[39,107],"data":[40],"between":[41],"different":[42],"channels.":[43],"We":[44,64],"compared":[45,81],"model":[47,77,91,114],"with":[48,82],"two":[49],"other":[50],"models,":[52],"e.g.,":[53],"(MLR)":[57],"sparse":[59],"(SMLR).":[63],"show":[65],"that":[66,100,111],"correct":[68],"classification":[69],"ratio":[70],"chromosomal":[72],"region":[73],"by":[74,86],"is":[78],"almost":[79],"93%,":[80],"90%":[83],"76%":[85],"MLR":[88],"SMLR":[90],"when":[92],"tested":[93],"comprehensive":[96],"database":[99],"established":[102],"p-value":[105],"three":[108],"models":[109],"indicating":[110],"can":[115],"significantly":[116],"improve":[117],"accuracy":[119],"analysis.":[123]},"counts_by_year":[{"year":2021,"cited_by_count":1}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}