{"id":"https://openalex.org/W2036190133","doi":"https://doi.org/10.1145/2185632.2185657","title":"Parameter estimation for stochastic hybrid models of biochemical reaction networks","display_name":"Parameter estimation for stochastic hybrid models of biochemical reaction networks","publication_year":2012,"publication_date":"2012-04-17","ids":{"openalex":"https://openalex.org/W2036190133","doi":"https://doi.org/10.1145/2185632.2185657","mag":"2036190133"},"language":"en","primary_location":{"id":"doi:10.1145/2185632.2185657","is_oa":false,"landing_page_url":"https://doi.org/10.1145/2185632.2185657","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 15th ACM international conference on Hybrid Systems: Computation and Control","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5057440935","display_name":"Linar Mikeev","orcid":null},"institutions":[{"id":"https://openalex.org/I91712215","display_name":"Saarland University","ror":"https://ror.org/01jdpyv68","country_code":"DE","type":"education","lineage":["https://openalex.org/I91712215"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Linar Mikeev","raw_affiliation_strings":["Saarland University, Saarbruecken, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Saarland University, Saarbruecken, Germany","institution_ids":["https://openalex.org/I91712215"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5089228948","display_name":"Verena Wolf","orcid":"https://orcid.org/0000-0001-8460-6007"},"institutions":[{"id":"https://openalex.org/I91712215","display_name":"Saarland University","ror":"https://ror.org/01jdpyv68","country_code":"DE","type":"education","lineage":["https://openalex.org/I91712215"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Verena Wolf","raw_affiliation_strings":["Saarland University, Saarbruecken, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Saarland University, Saarbruecken, Germany","institution_ids":["https://openalex.org/I91712215"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.075,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.75703821,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":97},"biblio":{"volume":null,"issue":null,"first_page":"155","last_page":"166"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.582786500453949},{"id":"https://openalex.org/keywords/estimation","display_name":"Estimation","score":0.5721973776817322},{"id":"https://openalex.org/keywords/estimation-theory","display_name":"Estimation theory","score":0.5289920568466187},{"id":"https://openalex.org/keywords/stochastic-process","display_name":"Stochastic process","score":0.4524754583835602},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.22872737050056458},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.1915683150291443},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.1637057363986969},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.14394575357437134}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.582786500453949},{"id":"https://openalex.org/C96250715","wikidata":"https://www.wikidata.org/wiki/Q965330","display_name":"Estimation","level":2,"score":0.5721973776817322},{"id":"https://openalex.org/C167928553","wikidata":"https://www.wikidata.org/wiki/Q1376021","display_name":"Estimation theory","level":2,"score":0.5289920568466187},{"id":"https://openalex.org/C8272713","wikidata":"https://www.wikidata.org/wiki/Q176737","display_name":"Stochastic process","level":2,"score":0.4524754583835602},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.22872737050056458},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.1915683150291443},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.1637057363986969},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.14394575357437134},{"id":"https://openalex.org/C201995342","wikidata":"https://www.wikidata.org/wiki/Q682496","display_name":"Systems engineering","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1145/2185632.2185657","is_oa":false,"landing_page_url":"https://doi.org/10.1145/2185632.2185657","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 15th ACM international conference on Hybrid Systems: Computation and Control","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W1966963894","https://openalex.org/W1972773888","https://openalex.org/W1972840179","https://openalex.org/W1976443948","https://openalex.org/W1985937069","https://openalex.org/W1989082976","https://openalex.org/W1996707446","https://openalex.org/W2012482128","https://openalex.org/W2019061200","https://openalex.org/W2039331233","https://openalex.org/W2071747231","https://openalex.org/W2082404215","https://openalex.org/W2095125040","https://openalex.org/W2140484213","https://openalex.org/W2147556100","https://openalex.org/W2157851226","https://openalex.org/W2167244112","https://openalex.org/W2168282770","https://openalex.org/W2952167521","https://openalex.org/W2952392477"],"related_works":["https://openalex.org/W2748952813","https://openalex.org/W2390279801","https://openalex.org/W2358668433","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W2382290278","https://openalex.org/W2478288626","https://openalex.org/W2350741829","https://openalex.org/W2530322880","https://openalex.org/W1596801655"],"abstract_inverted_index":{"The":[0],"dynamics":[1],"of":[2],"biochemical":[3],"reaction":[4],"networks":[5],"can":[6],"be":[7],"accurately":[8],"described":[9],"by":[10],"stochastic":[11],"hybrid":[12],"models,":[13],"where":[14],"we":[15],"assume":[16],"that":[17],"large":[18],"chemical":[19],"populations":[20,29],"evolve":[21],"deterministically":[22],"and":[23],"continuously":[24],"over":[25],"time":[26],"while":[27],"small":[28],"change":[30],"through":[31],"random":[32],"discrete":[33],"reactions.":[34]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}
