{"id":"https://openalex.org/W2018778479","doi":"https://doi.org/10.1145/1389095.1389300","title":"The effects of mutation and directed intervention crossover when applied to scheduling chemotherapy","display_name":"The effects of mutation and directed intervention crossover when applied to scheduling chemotherapy","publication_year":2008,"publication_date":"2008-07-12","ids":{"openalex":"https://openalex.org/W2018778479","doi":"https://doi.org/10.1145/1389095.1389300","mag":"2018778479"},"language":"en","primary_location":{"id":"doi:10.1145/1389095.1389300","is_oa":false,"landing_page_url":"https://doi.org/10.1145/1389095.1389300","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 10th annual conference on Genetic and evolutionary computation","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042523310","display_name":"Paul M. Godley","orcid":null},"institutions":[{"id":"https://openalex.org/I12093191","display_name":"University of Stirling","ror":"https://ror.org/045wgfr59","country_code":"GB","type":"education","lineage":["https://openalex.org/I12093191"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Paul M. Godley","raw_affiliation_strings":["University of Stirling, Stirling, Scotland, Uk"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Stirling, Stirling, Scotland, Uk","institution_ids":["https://openalex.org/I12093191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055890226","display_name":"David Cairns","orcid":"https://orcid.org/0000-0002-7404-9232"},"institutions":[{"id":"https://openalex.org/I12093191","display_name":"University of Stirling","ror":"https://ror.org/045wgfr59","country_code":"GB","type":"education","lineage":["https://openalex.org/I12093191"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"David E. Cairns","raw_affiliation_strings":["University of Stirling, Stirling, Scotland, Uk"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Stirling, Stirling, Scotland, Uk","institution_ids":["https://openalex.org/I12093191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061447838","display_name":"Julie Cowie","orcid":"https://orcid.org/0000-0002-4653-1283"},"institutions":[{"id":"https://openalex.org/I12093191","display_name":"University of Stirling","ror":"https://ror.org/045wgfr59","country_code":"GB","type":"education","lineage":["https://openalex.org/I12093191"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Julie Cowie","raw_affiliation_strings":["University Of Stirling, Stirling, Scotland, Uk","University of Stirling, Stirling, Scotland, Uk"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Of Stirling, Stirling, Scotland, Uk","institution_ids":["https://openalex.org/I12093191"]},{"raw_affiliation_string":"University of Stirling, Stirling, Scotland, Uk","institution_ids":["https://openalex.org/I12093191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064464537","display_name":"Kevin Swingler","orcid":"https://orcid.org/0000-0002-4517-9433"},"institutions":[{"id":"https://openalex.org/I12093191","display_name":"University of Stirling","ror":"https://ror.org/045wgfr59","country_code":"GB","type":"education","lineage":["https://openalex.org/I12093191"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Kevin M. Swingler","raw_affiliation_strings":["University of Stirling, Stirling, Scotland, Uk"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Stirling, Stirling, Scotland, Uk","institution_ids":["https://openalex.org/I12093191"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027645309","display_name":"John McCall","orcid":"https://orcid.org/0000-0003-1738-7056"},"institutions":[{"id":"https://openalex.org/I522815984","display_name":"Robert Gordon University","ror":"https://ror.org/04f0qj703","country_code":"GB","type":"education","lineage":["https://openalex.org/I522815984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"John McCall","raw_affiliation_strings":["The Robert Gordon University, Aberdeen, Scotland, Uk","The Robert Gordon University, Aberdeen, Scotland UK#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Robert Gordon University, Aberdeen, Scotland, Uk","institution_ids":["https://openalex.org/I522815984"]},{"raw_affiliation_string":"The Robert Gordon University, Aberdeen, Scotland UK#TAB#","institution_ids":["https://openalex.org/I522815984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.09094533,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"1105","last_page":"1106"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11663","display_name":"Viral Infectious Diseases and Gene Expression in Insects","score":0.9402999877929688,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11663","display_name":"Viral Infectious Diseases and Gene Expression in Insects","score":0.9402999877929688,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10494","display_name":"Plant Virus Research Studies","score":0.9060999751091003,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/crossover","display_name":"Crossover","score":0.9633797407150269},{"id":"https://openalex.org/keywords/scheduling","display_name":"Scheduling (production processes)","score":0.660457968711853},{"id":"https://openalex.org/keywords/intervention","display_name":"Intervention (counseling)","score":0.6434831023216248},{"id":"https://openalex.org/keywords/crossover-study","display_name":"Crossover study","score":0.6332512497901917},{"id":"https://openalex.org/keywords/mutation","display_name":"Mutation","score":0.4971778690814972},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.44500070810317993},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.3687572479248047},{"id":"https://openalex.org/keywords/mathematical-optimization","display_name":"Mathematical optimization","score":0.3045007884502411},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.1912124752998352},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.1218423843383789},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.10439419746398926},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.08106854557991028}],"concepts":[{"id":"https://openalex.org/C122507166","wikidata":"https://www.wikidata.org/wiki/Q628906","display_name":"Crossover","level":2,"score":0.9633797407150269},{"id":"https://openalex.org/C206729178","wikidata":"https://www.wikidata.org/wiki/Q2271896","display_name":"Scheduling (production processes)","level":2,"score":0.660457968711853},{"id":"https://openalex.org/C2780665704","wikidata":"https://www.wikidata.org/wiki/Q959298","display_name":"Intervention (counseling)","level":2,"score":0.6434831023216248},{"id":"https://openalex.org/C87813604","wikidata":"https://www.wikidata.org/wiki/Q1242899","display_name":"Crossover study","level":4,"score":0.6332512497901917},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.4971778690814972},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.44500070810317993},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3687572479248047},{"id":"https://openalex.org/C126255220","wikidata":"https://www.wikidata.org/wiki/Q141495","display_name":"Mathematical optimization","level":1,"score":0.3045007884502411},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.1912124752998352},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.1218423843383789},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.10439419746398926},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.08106854557991028},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1145/1389095.1389300","is_oa":false,"landing_page_url":"https://doi.org/10.1145/1389095.1389300","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 10th annual conference on Genetic and evolutionary computation","raw_type":"proceedings-article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.613.4768","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.613.4768","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.cs.stir.ac.uk/~kms/publications/fds-2008.pdf","raw_type":"text"},{"id":"pmh:oai:discovery.dundee.ac.uk:openaire_cris_publications/ccbc7018-c01a-48df-8bac-b7200fb25da8","is_oa":false,"landing_page_url":"https://discovery.dundee.ac.uk/en/publications/ccbc7018-c01a-48df-8bac-b7200fb25da8","pdf_url":null,"source":{"id":"https://openalex.org/S4306400523","display_name":"Discovery Research Portal (University of Dundee)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I177639307","host_organization_name":"University of Dundee","host_organization_lineage":["https://openalex.org/I177639307"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Godley, P, Cairns, D, Cowie, J, McCall, J & Swingler, K 2008, The Effects of Mutation and Directed Intervention Crossover When Applied to Scheduling Chemotherapy. in M Keijzer (ed.), Proceedings of the 10th annual conference on Genetic and evolutionary computation (GECCO '08). Association for Computing Machinery, New York, pp. 1105-1106. https://doi.org/10.1145/1389095.1389300","raw_type":"info:eu-repo/semantics/conferenceObject"},{"id":"pmh:oai:dspace.stir.ac.uk:1893/1527","is_oa":false,"landing_page_url":"http://dspace.stir.ac.uk/bitstream/1893/1527/1/t11pap386-godley.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S4306400268","display_name":"Stirling Online Research Repository (University of Stirling)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I12093191","host_organization_name":"University of Stirling","host_organization_lineage":["https://openalex.org/I12093191"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Conference Paper"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.7900000214576721}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W30442425","https://openalex.org/W1482684381","https://openalex.org/W1538287840","https://openalex.org/W1539490460","https://openalex.org/W1560883996","https://openalex.org/W1564289389","https://openalex.org/W1567204338","https://openalex.org/W1595498733","https://openalex.org/W1749062029","https://openalex.org/W1971772700","https://openalex.org/W2002664886","https://openalex.org/W2015775496","https://openalex.org/W2045268063","https://openalex.org/W2060994634","https://openalex.org/W2075226778","https://openalex.org/W2095110786","https://openalex.org/W2131310325","https://openalex.org/W2143935213","https://openalex.org/W2262228373","https://openalex.org/W6632325359"],"related_works":["https://openalex.org/W2136646847","https://openalex.org/W3190114291","https://openalex.org/W2023105019","https://openalex.org/W2952782365","https://openalex.org/W4296298573","https://openalex.org/W2231094482","https://openalex.org/W3027163692","https://openalex.org/W2984379141","https://openalex.org/W2993471286","https://openalex.org/W2155753975"],"abstract_inverted_index":{"This":[0,46],"paper":[1],"discusses":[2],"the":[3,15,27,33,38,41],"effects":[4],"of":[5,17,40],"mutation":[6,58],"and":[7,59],"directed":[8,28,50],"intervention":[9,29,34,51],"crossover":[10,52],"approaches":[11],"when":[12,66],"applied":[13,67],"to":[14,57,61,68],"derivation":[16],"cancer":[18,69],"chemotherapy":[19,70],"treatment":[20,71],"schedules.":[21],"Unlike":[22],"traditional":[23],"Uniform":[24],"Crossover":[25],"(UC),":[26],"techniques":[30],"actively":[31],"choose":[32],"level":[35],"based":[36],"on":[37],"fitness":[39],"parents":[42],"selected":[43],"for":[44],"crossover.":[45],"work":[47],"describes":[48],"how":[49],"principles":[53],"are":[54],"more":[55],"robust":[56],"lead":[60],"significant":[62],"improvement":[63],"over":[64],"UC":[65],"scheduling.":[72]},"counts_by_year":[{"year":2014,"cited_by_count":1}],"updated_date":"2026-07-02T09:51:11.867554","created_date":"2025-10-10T00:00:00"}