{"id":"https://openalex.org/W2132598957","doi":"https://doi.org/10.1145/1143997.1144042","title":"Genetic programming for human oral bioavailability of drugs","display_name":"Genetic programming for human oral bioavailability of drugs","publication_year":2006,"publication_date":"2006-07-08","ids":{"openalex":"https://openalex.org/W2132598957","doi":"https://doi.org/10.1145/1143997.1144042","mag":"2132598957"},"language":"en","primary_location":{"id":"doi:10.1145/1143997.1144042","is_oa":false,"landing_page_url":"https://doi.org/10.1145/1143997.1144042","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 8th annual conference on Genetic and evolutionary computation","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5011390491","display_name":"Francesco Archetti","orcid":"https://orcid.org/0000-0003-1131-3830"},"institutions":[{"id":"https://openalex.org/I66752286","display_name":"University of Milano-Bicocca","ror":"https://ror.org/01ynf4891","country_code":"IT","type":"education","lineage":["https://openalex.org/I66752286"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Francesco Archetti","raw_affiliation_strings":["University of Milano-Bicocca, Milan, Italy"],"affiliations":[{"raw_affiliation_string":"University of Milano-Bicocca, Milan, Italy","institution_ids":["https://openalex.org/I66752286"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110233559","display_name":"Stefano Lanzeni","orcid":null},"institutions":[{"id":"https://openalex.org/I66752286","display_name":"University of Milano-Bicocca","ror":"https://ror.org/01ynf4891","country_code":"IT","type":"education","lineage":["https://openalex.org/I66752286"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Stefano Lanzeni","raw_affiliation_strings":["University of Milano-Bicocca, Milan, Italy"],"affiliations":[{"raw_affiliation_string":"University of Milano-Bicocca, Milan, Italy","institution_ids":["https://openalex.org/I66752286"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061496529","display_name":"Enza Messina","orcid":"https://orcid.org/0000-0002-4062-0824"},"institutions":[{"id":"https://openalex.org/I66752286","display_name":"University of Milano-Bicocca","ror":"https://ror.org/01ynf4891","country_code":"IT","type":"education","lineage":["https://openalex.org/I66752286"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Enza Messina","raw_affiliation_strings":["University of Milano-Bicocca, Milan, Italy"],"affiliations":[{"raw_affiliation_string":"University of Milano-Bicocca, Milan, Italy","institution_ids":["https://openalex.org/I66752286"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5056916227","display_name":"Leonardo Vanneschi","orcid":"https://orcid.org/0000-0003-4732-3328"},"institutions":[{"id":"https://openalex.org/I66752286","display_name":"University of Milano-Bicocca","ror":"https://ror.org/01ynf4891","country_code":"IT","type":"education","lineage":["https://openalex.org/I66752286"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Leonardo Vanneschi","raw_affiliation_strings":["University of Milano-Bicocca, Milan, Italy"],"affiliations":[{"raw_affiliation_string":"University of Milano-Bicocca, Milan, Italy","institution_ids":["https://openalex.org/I66752286"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5011390491"],"corresponding_institution_ids":["https://openalex.org/I66752286"],"apc_list":null,"apc_paid":null,"fwci":4.6573,"has_fulltext":false,"cited_by_count":48,"citation_normalized_percentile":{"value":0.94639473,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":null,"issue":null,"first_page":"255","last_page":"262"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11975","display_name":"Evolutionary Algorithms and Applications","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11975","display_name":"Evolutionary Algorithms and Applications","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11663","display_name":"Viral Infectious Diseases and Gene Expression in Insects","score":0.9919999837875366,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9891999959945679,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bioavailability","display_name":"Bioavailability","score":0.8785021901130676},{"id":"https://openalex.org/keywords/genetic-programming","display_name":"Genetic programming","score":0.807299017906189},{"id":"https://openalex.org/keywords/biomedicine","display_name":"Biomedicine","score":0.6676021814346313},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6433612108230591},{"id":"https://openalex.org/keywords/generalization","display_name":"Generalization","score":0.6020185947418213},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.46671053767204285},{"id":"https://openalex.org/keywords/biochemical-engineering","display_name":"Biochemical engineering","score":0.431590735912323},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.42165881395339966},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.1747226119041443},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.16354063153266907},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.14970865845680237},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.13109761476516724}],"concepts":[{"id":"https://openalex.org/C181389837","wikidata":"https://www.wikidata.org/wiki/Q461809","display_name":"Bioavailability","level":2,"score":0.8785021901130676},{"id":"https://openalex.org/C110332635","wikidata":"https://www.wikidata.org/wiki/Q629498","display_name":"Genetic programming","level":2,"score":0.807299017906189},{"id":"https://openalex.org/C66782513","wikidata":"https://www.wikidata.org/wiki/Q864601","display_name":"Biomedicine","level":2,"score":0.6676021814346313},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6433612108230591},{"id":"https://openalex.org/C177148314","wikidata":"https://www.wikidata.org/wiki/Q170084","display_name":"Generalization","level":2,"score":0.6020185947418213},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.46671053767204285},{"id":"https://openalex.org/C183696295","wikidata":"https://www.wikidata.org/wiki/Q2487696","display_name":"Biochemical engineering","level":1,"score":0.431590735912323},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.42165881395339966},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.1747226119041443},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.16354063153266907},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.14970865845680237},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.13109761476516724},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1145/1143997.1144042","is_oa":false,"landing_page_url":"https://doi.org/10.1145/1143997.1144042","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 8th annual conference on Genetic and evolutionary computation","raw_type":"proceedings-article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.216.5152","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.216.5152","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.cs.bham.ac.uk/~wbl/biblio/gecco2006/docs/p255.pdf","raw_type":"text"},{"id":"pmh:oai:boa.unimib.it:10281/5586","is_oa":false,"landing_page_url":"http://hdl.handle.net/10281/5586","pdf_url":null,"source":{"id":"https://openalex.org/S4306401259","display_name":"BOA (University of Milano-Bicocca)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I66752286","host_organization_name":"University of Milano-Bicocca","host_organization_lineage":["https://openalex.org/I66752286"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/conferenceObject"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W17285715","https://openalex.org/W53373509","https://openalex.org/W158805453","https://openalex.org/W185703129","https://openalex.org/W1495061682","https://openalex.org/W1519072852","https://openalex.org/W1545231783","https://openalex.org/W1579198272","https://openalex.org/W1582940840","https://openalex.org/W1964357740","https://openalex.org/W1989451208","https://openalex.org/W2021279952","https://openalex.org/W2044069680","https://openalex.org/W2058815839","https://openalex.org/W2105649494","https://openalex.org/W2124776405","https://openalex.org/W2129249398","https://openalex.org/W2135732933","https://openalex.org/W2148694408","https://openalex.org/W2152837692","https://openalex.org/W2161723120","https://openalex.org/W3004042307","https://openalex.org/W4248107770","https://openalex.org/W6632909133"],"related_works":["https://openalex.org/W2017899917","https://openalex.org/W2080571363","https://openalex.org/W2046280088","https://openalex.org/W1505739641","https://openalex.org/W2110192055","https://openalex.org/W2073177056","https://openalex.org/W2481322495","https://openalex.org/W2044251933","https://openalex.org/W118449968","https://openalex.org/W2099575842"],"abstract_inverted_index":{"Automatically":[0],"assessing":[1],"the":[2,7,62,67,75,80,83,87,92,107,118,123],"value":[3],"of":[4,10,30,40,53,77,79,82,86,91,125],"bioavailability":[5,111],"from":[6,74],"chemical":[8],"structure":[9],"a":[11,14,51,103],"molecule":[12],"is":[13],"very":[15],"important":[16],"issue":[17],"in":[18,115],"biomedicine":[19],"and":[20,90,97],"pharmacology.":[21],"In":[22],"this":[23,48],"paper,":[24],"we":[25],"present":[26],"an":[27],"empirical":[28],"study":[29],"some":[31],"well":[32],"known":[33,56],"Machine":[34],"Learning":[35],"techniques,":[36],"including":[37],"various":[38],"versions":[39],"Genetic":[41,58],"Programming,":[42],"which":[43],"have":[44,70],"been":[45,71],"trained":[46],"to":[47,106],"aim":[49],"using":[50],"dataset":[52],"molecules":[54,126],"with":[55,129],"bioavailability.":[57,131],"Programming":[59],"has":[60],"proven":[61],"most":[63],"promising":[64],"technique":[65],"among":[66],"ones":[68],"that":[69],"considered":[72],"both":[73],"point":[76],"view":[78],"accurateness":[81],"solutions":[84],"proposed,":[85],"generalization":[88],"capabilities":[89],"correlation":[93],"between":[94],"predicted":[95],"data":[96],"correct":[98],"ones.":[99],"Our":[100],"work":[101],"represents":[102],"first":[104],"answer":[105],"demand":[108],"for":[109],"quantitative":[110],"estimation":[112],"methods":[113],"proposed":[114],"literature,":[116],"since":[117],"previous":[119],"contributions":[120],"focus":[121],"on":[122],"classification":[124],"into":[127],"classes":[128],"similar":[130]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":2}],"updated_date":"2026-04-05T17:49:38.594831","created_date":"2025-10-10T00:00:00"}