{"id":"https://openalex.org/W2061039778","doi":"https://doi.org/10.1145/1141277.1141323","title":"A novel data mining algorithm for reconstructing gene regulatory networks from microarray data","display_name":"A novel data mining algorithm for reconstructing gene regulatory networks from microarray data","publication_year":2006,"publication_date":"2006-04-23","ids":{"openalex":"https://openalex.org/W2061039778","doi":"https://doi.org/10.1145/1141277.1141323","mag":"2061039778"},"language":"en","primary_location":{"id":"doi:10.1145/1141277.1141323","is_oa":false,"landing_page_url":"https://doi.org/10.1145/1141277.1141323","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 2006 ACM symposium on Applied computing","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110693170","display_name":"C. H. Patrick","orcid":null},"institutions":[{"id":"https://openalex.org/I14243506","display_name":"Hong Kong Polytechnic University","ror":"https://ror.org/0030zas98","country_code":"HK","type":"education","lineage":["https://openalex.org/I14243506"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Patrick C. H. Ma","raw_affiliation_strings":["The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR, China","The Hong Kong Polytechnic University,,,Hung Hom, Kowloon,,Hong Kong SAR, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR, China","institution_ids":["https://openalex.org/I14243506"]},{"raw_affiliation_string":"The Hong Kong Polytechnic University,,,Hung Hom, Kowloon,,Hong Kong SAR, China","institution_ids":["https://openalex.org/I14243506"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5107049960","display_name":"Keith C. C. Chan","orcid":"https://orcid.org/0000-0001-7962-6564"},"institutions":[{"id":"https://openalex.org/I14243506","display_name":"Hong Kong Polytechnic University","ror":"https://ror.org/0030zas98","country_code":"HK","type":"education","lineage":["https://openalex.org/I14243506"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Keith C. C. Chan","raw_affiliation_strings":["The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR, China","The Hong Kong Polytechnic University,,,Hung Hom, Kowloon,,Hong Kong SAR, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR, China","institution_ids":["https://openalex.org/I14243506"]},{"raw_affiliation_string":"The Hong Kong Polytechnic University,,,Hung Hom, Kowloon,,Hong Kong SAR, China","institution_ids":["https://openalex.org/I14243506"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I14243506"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.13752983,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"202","last_page":"203"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9819999933242798,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9782999753952026,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.6911611557006836},{"id":"https://openalex.org/keywords/probabilistic-logic","display_name":"Probabilistic logic","score":0.6427686810493469},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6350622177124023},{"id":"https://openalex.org/keywords/association-rule-learning","display_name":"Association rule learning","score":0.6248208284378052},{"id":"https://openalex.org/keywords/gene-regulatory-network","display_name":"Gene regulatory network","score":0.5746124982833862},{"id":"https://openalex.org/keywords/microarray-analysis-techniques","display_name":"Microarray analysis techniques","score":0.5307360291481018},{"id":"https://openalex.org/keywords/feature-selection","display_name":"Feature selection","score":0.5112698078155518},{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.4670941233634949},{"id":"https://openalex.org/keywords/measure","display_name":"Measure (data warehouse)","score":0.440075159072876},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.43697112798690796},{"id":"https://openalex.org/keywords/selection","display_name":"Selection (genetic algorithm)","score":0.4360075294971466},{"id":"https://openalex.org/keywords/biological-data","display_name":"Biological data","score":0.4251112937927246},{"id":"https://openalex.org/keywords/expression","display_name":"Expression (computer science)","score":0.4227999448776245},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.3623952269554138},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.34292107820510864},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.3015313744544983},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.22656548023223877},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.20961815118789673},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.137180894613266},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.0767831802368164}],"concepts":[{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.6911611557006836},{"id":"https://openalex.org/C49937458","wikidata":"https://www.wikidata.org/wiki/Q2599292","display_name":"Probabilistic logic","level":2,"score":0.6427686810493469},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6350622177124023},{"id":"https://openalex.org/C193524817","wikidata":"https://www.wikidata.org/wiki/Q386780","display_name":"Association rule learning","level":2,"score":0.6248208284378052},{"id":"https://openalex.org/C67339327","wikidata":"https://www.wikidata.org/wiki/Q1502576","display_name":"Gene regulatory network","level":4,"score":0.5746124982833862},{"id":"https://openalex.org/C8415881","wikidata":"https://www.wikidata.org/wiki/Q6839217","display_name":"Microarray analysis techniques","level":4,"score":0.5307360291481018},{"id":"https://openalex.org/C148483581","wikidata":"https://www.wikidata.org/wiki/Q446488","display_name":"Feature selection","level":2,"score":0.5112698078155518},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.4670941233634949},{"id":"https://openalex.org/C2780009758","wikidata":"https://www.wikidata.org/wiki/Q6804172","display_name":"Measure (data warehouse)","level":2,"score":0.440075159072876},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.43697112798690796},{"id":"https://openalex.org/C81917197","wikidata":"https://www.wikidata.org/wiki/Q628760","display_name":"Selection (genetic algorithm)","level":2,"score":0.4360075294971466},{"id":"https://openalex.org/C201797286","wikidata":"https://www.wikidata.org/wiki/Q4914986","display_name":"Biological data","level":2,"score":0.4251112937927246},{"id":"https://openalex.org/C90559484","wikidata":"https://www.wikidata.org/wiki/Q778379","display_name":"Expression (computer science)","level":2,"score":0.4227999448776245},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.3623952269554138},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.34292107820510864},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3015313744544983},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.22656548023223877},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.20961815118789673},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.137180894613266},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0767831802368164},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1145/1141277.1141323","is_oa":false,"landing_page_url":"https://doi.org/10.1145/1141277.1141323","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 2006 ACM symposium on Applied computing","raw_type":"proceedings-article"},{"id":"pmh:oai:ira.lib.polyu.edu.hk:10397/39803","is_oa":false,"landing_page_url":"http://hdl.handle.net/10397/39803","pdf_url":null,"source":{"id":"https://openalex.org/S4306400205","display_name":"PolyU Institutional Research Archive (Hong Kong Polytechnic University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I14243506","host_organization_name":"Hong Kong Polytechnic University","host_organization_lineage":["https://openalex.org/I14243506"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Conference Paper"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":5,"referenced_works":["https://openalex.org/W201726549","https://openalex.org/W2097557760","https://openalex.org/W2103453943","https://openalex.org/W2125055259","https://openalex.org/W2131820435"],"related_works":["https://openalex.org/W2751920613","https://openalex.org/W2415164632","https://openalex.org/W2238349241","https://openalex.org/W2355668701","https://openalex.org/W2370453500","https://openalex.org/W1561334777","https://openalex.org/W1982897783","https://openalex.org/W2131550814","https://openalex.org/W1998993447","https://openalex.org/W3145364936"],"abstract_inverted_index":{"In":[0],"this":[1],"paper,":[2],"we":[3],"propose":[4],"a":[5],"novel":[6],"data":[7,36,79],"mining":[8],"algorithm":[9],"for":[10,37,46,59],"reconstructing":[11,102],"gene":[12,66],"regulatory":[13,94],"networks":[14],"(GRNs)":[15],"from":[16],"microarray":[17],"data.":[18],"By":[19],"making":[20],"use":[21],"of":[22,41,96,106],"the":[23,44,70,87,103],"proposed":[24],"probabilistic":[25],"measure,":[26],"it":[27,52,82],"is":[28,83],"able":[29],"to":[30],"mine":[31],"noisy,":[32],"high":[33],"dimensional":[34],"expression":[35,67,78],"interesting":[38],"association":[39,89],"patterns":[40,57,68,90],"genes":[42,97],"without":[43],"need":[45],"additional":[47],"feature":[48],"selection":[49],"procedures.":[50],"Moreover,":[51],"can":[53],"make":[54],"explicit":[55],"hidden":[56],"discovered":[58,88],"possible":[60],"biological":[61],"interpretation":[62],"and":[63,86],"also":[64],"predict":[65],"in":[69],"unseen":[71],"tissue":[72],"samples.":[73],"Experimental":[74],"results":[75],"on":[76],"real":[77],"show":[80],"that":[81,98],"very":[84],"effective":[85],"reveal":[91],"biologically":[92],"meaningful":[93],"relationships":[95],"could":[99],"help":[100],"users":[101],"underlying":[104],"structures":[105],"GRNs.":[107]},"counts_by_year":[],"updated_date":"2026-07-29T14:22:42.915294","created_date":"2025-10-10T00:00:00"}