{"id":"https://openalex.org/W2119654550","doi":"https://doi.org/10.1142/s0219525911002913","title":"THE EVOLUTION OF COMPLEXITY IN SELF-MAINTAINING CELLULAR INFORMATION PROCESSING NETWORKS","display_name":"THE EVOLUTION OF COMPLEXITY IN SELF-MAINTAINING CELLULAR INFORMATION PROCESSING NETWORKS","publication_year":2011,"publication_date":"2011-02-01","ids":{"openalex":"https://openalex.org/W2119654550","doi":"https://doi.org/10.1142/s0219525911002913","mag":"2119654550"},"language":"en","primary_location":{"id":"doi:10.1142/s0219525911002913","is_oa":false,"landing_page_url":"https://doi.org/10.1142/s0219525911002913","pdf_url":null,"source":{"id":"https://openalex.org/S107361000","display_name":"Advances in Complex Systems","issn_l":"0219-5259","issn":["0219-5259","1793-6802","1793-9615","1793-9623"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319815","host_organization_name":"World Scientific","host_organization_lineage":["https://openalex.org/P4310319815"],"host_organization_lineage_names":["World Scientific"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Complex Systems","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090163774","display_name":"James Decraene","orcid":null},"institutions":[{"id":"https://openalex.org/I172675005","display_name":"Nanyang Technological University","ror":"https://ror.org/02e7b5302","country_code":"SG","type":"education","lineage":["https://openalex.org/I172675005"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"JAMES DECRAENE","raw_affiliation_strings":["Parallel and Distributed Computing Centre, School of Computer Engineering, Nanyang Technological University, Singapore","Parallel and Distributed Computing Centre, School of Computer Engineering, Nanyang Technological University, Singapore#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Parallel and Distributed Computing Centre, School of Computer Engineering, Nanyang Technological University, Singapore","institution_ids":["https://openalex.org/I172675005"]},{"raw_affiliation_string":"Parallel and Distributed Computing Centre, School of Computer Engineering, Nanyang Technological University, Singapore#TAB#","institution_ids":["https://openalex.org/I172675005"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052239696","display_name":"Barry McMullin","orcid":"https://orcid.org/0000-0002-5789-2068"},"institutions":[{"id":"https://openalex.org/I42934936","display_name":"Dublin City University","ror":"https://ror.org/04a1a1e81","country_code":"IE","type":"education","lineage":["https://openalex.org/I42934936"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"BARRY MCMULLIN","raw_affiliation_strings":["Artificial Life Laboratory, The Rince Institute, Dublin City University, Dublin, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Artificial Life Laboratory, The Rince Institute, Dublin City University, Dublin, Ireland","institution_ids":["https://openalex.org/I42934936"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.1799,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.65800555,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"14","issue":"01","first_page":"55","last_page":"75"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11445","display_name":"Origins and Evolution of Life","score":0.9955000281333923,"subfield":{"id":"https://openalex.org/subfields/3103","display_name":"Astronomy and Astrophysics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11445","display_name":"Origins and Evolution of Life","score":0.9955000281333923,"subfield":{"id":"https://openalex.org/subfields/3103","display_name":"Astronomy and Astrophysics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9912999868392944,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12162","display_name":"Cellular Automata and Applications","score":0.9803000092506409,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6748840808868408},{"id":"https://openalex.org/keywords/formalism","display_name":"Formalism (music)","score":0.6146757006645203},{"id":"https://openalex.org/keywords/artificial-life","display_name":"Artificial life","score":0.5632399916648865},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5001819133758545},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.45765507221221924},{"id":"https://openalex.org/keywords/information-processing","display_name":"Information processing","score":0.4465048611164093},{"id":"https://openalex.org/keywords/rewriting","display_name":"Rewriting","score":0.41806408762931824},{"id":"https://openalex.org/keywords/inheritance","display_name":"Inheritance (genetic algorithm)","score":0.41509148478507996},{"id":"https://openalex.org/keywords/self-organization","display_name":"Self-organization","score":0.4113454818725586},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.20592361688613892}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6748840808868408},{"id":"https://openalex.org/C73301696","wikidata":"https://www.wikidata.org/wiki/Q5469984","display_name":"Formalism (music)","level":3,"score":0.6146757006645203},{"id":"https://openalex.org/C19273510","wikidata":"https://www.wikidata.org/wiki/Q263847","display_name":"Artificial life","level":2,"score":0.5632399916648865},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5001819133758545},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.45765507221221924},{"id":"https://openalex.org/C87868495","wikidata":"https://www.wikidata.org/wiki/Q750843","display_name":"Information processing","level":2,"score":0.4465048611164093},{"id":"https://openalex.org/C154690210","wikidata":"https://www.wikidata.org/wiki/Q1668499","display_name":"Rewriting","level":2,"score":0.41806408762931824},{"id":"https://openalex.org/C2780902518","wikidata":"https://www.wikidata.org/wiki/Q6033780","display_name":"Inheritance (genetic algorithm)","level":3,"score":0.41509148478507996},{"id":"https://openalex.org/C106960710","wikidata":"https://www.wikidata.org/wiki/Q609408","display_name":"Self-organization","level":2,"score":0.4113454818725586},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.20592361688613892},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.0},{"id":"https://openalex.org/C142362112","wikidata":"https://www.wikidata.org/wiki/Q735","display_name":"Art","level":0,"score":0.0},{"id":"https://openalex.org/C558565934","wikidata":"https://www.wikidata.org/wiki/Q2743","display_name":"Musical","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C153349607","wikidata":"https://www.wikidata.org/wiki/Q36649","display_name":"Visual arts","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1142/s0219525911002913","is_oa":false,"landing_page_url":"https://doi.org/10.1142/s0219525911002913","pdf_url":null,"source":{"id":"https://openalex.org/S107361000","display_name":"Advances in Complex Systems","issn_l":"0219-5259","issn":["0219-5259","1793-6802","1793-9615","1793-9623"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319815","host_organization_name":"World Scientific","host_organization_lineage":["https://openalex.org/P4310319815"],"host_organization_lineage_names":["World Scientific"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Complex Systems","raw_type":"journal-article"},{"id":"pmh:http://www.rian.ie/48098/","is_oa":false,"landing_page_url":"http://doras.dcu.ie/16292/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400033","display_name":"Arrow@dit (Dublin Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I115570527","host_organization_name":"Dublin Institute of Technology","host_organization_lineage":["https://openalex.org/I115570527"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Decraene, James and McMullin, Barry ORCID: 0000-0002-5789-2068 &lt;https://orcid.org/0000-0002-5789-2068&gt; (2011) The Evolution of complexity in self-maintaining cellular information processing networks. Advances in Complex Systems, 14 (1). pp. 55-75. ISSN 0219-5259","raw_type":"Other"},{"id":"pmh:oai:RePEc:wsi:acsxxx:v:14:y:2011:i:01:n:s0219525911002913","is_oa":false,"landing_page_url":"http://www.worldscientific.com/doi/abs/10.1142/S0219525911002913","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:RePEc:wsi:acsxxx:v:14:y:2011:i:01:p:55-75","is_oa":false,"landing_page_url":"http://www.worldscinet.com/cgi-bin/details.cgi?type=html&amp;id=pii:S0219525911002913","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"article"},{"id":"pmh:oai:dr.ntu.edu.sg:10356/93823","is_oa":false,"landing_page_url":"https://hdl.handle.net/10356/93823","pdf_url":null,"source":{"id":"https://openalex.org/S4306402609","display_name":"DR-NTU (Nanyang Technological University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I172675005","host_organization_name":"Nanyang Technological University","host_organization_lineage":["https://openalex.org/I172675005"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W96698116","https://openalex.org/W1497256448","https://openalex.org/W1534957815","https://openalex.org/W1548915380","https://openalex.org/W1571624160","https://openalex.org/W1659842140","https://openalex.org/W1765868291","https://openalex.org/W1974140070","https://openalex.org/W1977943300","https://openalex.org/W1984252786","https://openalex.org/W1993748480","https://openalex.org/W2004964623","https://openalex.org/W2011214280","https://openalex.org/W2013812761","https://openalex.org/W2021767817","https://openalex.org/W2031564575","https://openalex.org/W2158888644","https://openalex.org/W2171303401","https://openalex.org/W2289587704","https://openalex.org/W2556090403","https://openalex.org/W2796006040","https://openalex.org/W2952968008","https://openalex.org/W3011244588","https://openalex.org/W3102310679","https://openalex.org/W3204089767","https://openalex.org/W3214949894","https://openalex.org/W4300925890"],"related_works":["https://openalex.org/W2120204135","https://openalex.org/W1796293478","https://openalex.org/W2139396251","https://openalex.org/W1577544887","https://openalex.org/W1573537275","https://openalex.org/W2921316940","https://openalex.org/W3044818641","https://openalex.org/W2151565113","https://openalex.org/W2795582258","https://openalex.org/W1826979868"],"abstract_inverted_index":{"We":[0,60,81,155],"examine":[1],"the":[2,9,28,62,69,113,123,150,158,183,186],"role":[3],"of":[4,11,33,57,64,73,76,88,152,160,170,177,185,190],"self-maintenance":[5,22,66],"(collective":[6],"autocatalysis)":[7],"in":[8,192],"evolution":[10,70,159],"computational":[12],"biochemical":[13],"networks.":[14],"In":[15],"primitive":[16],"proto-cells":[17],"(lacking":[18],"separate":[19],"genetic":[20],"machinery)":[21],"is":[23,98,120],"a":[24,93,108,141,167],"necessary":[25],"condition":[26],"for":[27],"direct":[29],"reproduction":[30],"and":[31,71,163,172],"inheritance":[32],"what":[34],"we":[35,131],"here":[36],"term":[37,109],"Cellular":[38],"Information":[39],"Processing":[40],"Networks":[41],"(CIPNs).":[42],"Indeed,":[43],"partially":[44],"reproduced":[45],"or":[46,54],"defective":[47],"CIPNs":[48,74,91,165],"may":[49],"generally":[50],"lead":[51],"to":[52,137,149,182],"malfunctioning":[53],"premature":[55],"death":[56],"affected":[58],"cells.":[59],"explore":[61],"interaction":[63],"this":[65,129],"property":[67],"with":[68],"adaptation":[72],"capable":[75,87],"distinct":[77],"information":[78,144],"processing":[79,145],"abilities.":[80],"present":[82],"an":[83,99,134],"evolutionary":[84,188],"simulation":[85],"platform":[86],"evolving":[89],"artificial":[90,135,193],"from":[92,122],"bottom-up":[94],"perspective.":[95],"This":[96,175],"system":[97,111],"agent-based":[100],"multi-level":[101],"selectional":[102],"Artificial":[103],"Chemistry":[104],"(AC)":[105],"which":[106],"employs":[107],"rewriting":[110],"called":[112],"Molecular":[114],"Classifier":[115],"System":[116],"(MCS.bl).":[117],"The":[118],"latter":[119],"derived":[121],"Holland":[124],"broadcast":[125],"language":[126],"formalism.":[127],"Using":[128],"system,":[130],"successfully":[132],"evolve":[133],"CIPN":[136],"improve":[138],"performance":[139],"on":[140],"simple":[142],"pre-specified":[143],"task":[146],"whilst":[147],"subject":[148],"constraint":[151],"continuous":[153],"self-maintenance.":[154],"also":[156],"describe":[157],"self-maintaining,":[161],"cross-talking":[162],"multi-tasking,":[164],"exhibiting":[166],"higher":[168],"level":[169],"topological":[171],"functional":[173],"complexity.":[174],"proof":[176],"concept":[178],"aims":[179],"at":[180],"contributing":[181],"understanding":[184],"open-ended":[187],"growth":[189],"complexity":[191],"systems.":[194]},"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-08-21T09:56:20.448147","created_date":"2025-10-10T00:00:00"}
