{"id":"https://openalex.org/W4410242235","doi":"https://doi.org/10.1142/s012906572550042x","title":"Optimizing Dementia Diagnosis Through Distance-Correlation Feature Space and Dimensionality Reduction","display_name":"Optimizing Dementia Diagnosis Through Distance-Correlation Feature Space and Dimensionality Reduction","publication_year":2025,"publication_date":"2025-05-09","ids":{"openalex":"https://openalex.org/W4410242235","doi":"https://doi.org/10.1142/s012906572550042x","pmid":"https://pubmed.ncbi.nlm.nih.gov/40506829"},"language":"en","primary_location":{"id":"doi:10.1142/s012906572550042x","is_oa":false,"landing_page_url":"https://doi.org/10.1142/s012906572550042x","pdf_url":null,"source":{"id":"https://openalex.org/S197665576","display_name":"International Journal of Neural Systems","issn_l":"0129-0657","issn":["0129-0657","1793-6462"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319815","host_organization_name":"World Scientific","host_organization_lineage":["https://openalex.org/P4310319815"],"host_organization_lineage_names":["World Scientific"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Neural Systems","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.1142/S012906572550042X","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5098940859","display_name":"Pablo Zubasti","orcid":"https://orcid.org/0009-0006-1906-118X"},"institutions":[{"id":"https://openalex.org/I50357001","display_name":"Universidad Carlos III de Madrid","ror":"https://ror.org/03ths8210","country_code":"ES","type":"education","lineage":["https://openalex.org/I50357001"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Pablo Zubasti","raw_affiliation_strings":["Department of Computer Science and Engineering, Universidad Carlos III de Madrid, Colmenarejo 28270, Spain"],"raw_orcid":"https://orcid.org/0009-0006-1906-118X","affiliations":[{"raw_affiliation_string":"Department of Computer Science and Engineering, Universidad Carlos III de Madrid, Colmenarejo 28270, Spain","institution_ids":["https://openalex.org/I50357001"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078240188","display_name":"Miguel \u00c1. Patricio","orcid":"https://orcid.org/0000-0002-9304-826X"},"institutions":[{"id":"https://openalex.org/I50357001","display_name":"Universidad Carlos III de Madrid","ror":"https://ror.org/03ths8210","country_code":"ES","type":"education","lineage":["https://openalex.org/I50357001"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Miguel A. Patricio","raw_affiliation_strings":["Department of Computer Science and Engineering, Universidad Carlos III de Madrid, Colmenarejo 28270, Spain"],"raw_orcid":"https://orcid.org/0000-0002-9304-826X","affiliations":[{"raw_affiliation_string":"Department of Computer Science and Engineering, Universidad Carlos III de Madrid, Colmenarejo 28270, Spain","institution_ids":["https://openalex.org/I50357001"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079499955","display_name":"Antonio Berlanga","orcid":"https://orcid.org/0000-0002-5564-399X"},"institutions":[{"id":"https://openalex.org/I50357001","display_name":"Universidad Carlos III de Madrid","ror":"https://ror.org/03ths8210","country_code":"ES","type":"education","lineage":["https://openalex.org/I50357001"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Antonio Berlanga","raw_affiliation_strings":["Department of Computer Science and Engineering, Universidad Carlos III de Madrid, Colmenarejo 28270, Spain"],"raw_orcid":"https://orcid.org/0000-0002-5564-399X","affiliations":[{"raw_affiliation_string":"Department of Computer Science and Engineering, Universidad Carlos III de Madrid, Colmenarejo 28270, Spain","institution_ids":["https://openalex.org/I50357001"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059583924","display_name":"Jos\u00e9 M. Molina","orcid":"https://orcid.org/0000-0002-7484-7357"},"institutions":[{"id":"https://openalex.org/I50357001","display_name":"Universidad Carlos III de Madrid","ror":"https://ror.org/03ths8210","country_code":"ES","type":"education","lineage":["https://openalex.org/I50357001"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Jose M. Molina","raw_affiliation_strings":["Department of Computer Science and Engineering, Universidad Carlos III de Madrid, Colmenarejo 28270, Spain"],"raw_orcid":"https://orcid.org/0000-0002-7484-7357","affiliations":[{"raw_affiliation_string":"Department of Computer Science and Engineering, Universidad Carlos III de Madrid, Colmenarejo 28270, Spain","institution_ids":["https://openalex.org/I50357001"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5098940859"],"corresponding_institution_ids":["https://openalex.org/I50357001"],"apc_list":null,"apc_paid":null,"fwci":2.1733,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.88298411,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":98},"biblio":{"volume":"35","issue":"09","first_page":"2550042","last_page":"2550042"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11273","display_name":"Advanced Graph Neural Networks","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11273","display_name":"Advanced Graph Neural Networks","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11307","display_name":"Domain Adaptation and Few-Shot Learning","score":0.987500011920929,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dimensionality-reduction","display_name":"Dimensionality reduction","score":0.8809084296226501},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6973174810409546},{"id":"https://openalex.org/keywords/scalability","display_name":"Scalability","score":0.6557324528694153},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6236627101898193},{"id":"https://openalex.org/keywords/curse-of-dimensionality","display_name":"Curse of dimensionality","score":0.6182475686073303},{"id":"https://openalex.org/keywords/feature-selection","display_name":"Feature selection","score":0.5911719799041748},{"id":"https://openalex.org/keywords/context","display_name":"Context (archaeology)","score":0.5782498121261597},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.5140489339828491},{"id":"https://openalex.org/keywords/process","display_name":"Process (computing)","score":0.45281121134757996},{"id":"https://openalex.org/keywords/reduction","display_name":"Reduction (mathematics)","score":0.4491385221481323},{"id":"https://openalex.org/keywords/feature-extraction","display_name":"Feature extraction","score":0.44518017768859863},{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.43325936794281006},{"id":"https://openalex.org/keywords/graph","display_name":"Graph","score":0.43122535943984985},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.4174753427505493},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.34883034229278564},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.18159714341163635},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.1376987099647522}],"concepts":[{"id":"https://openalex.org/C70518039","wikidata":"https://www.wikidata.org/wiki/Q16000077","display_name":"Dimensionality reduction","level":2,"score":0.8809084296226501},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6973174810409546},{"id":"https://openalex.org/C48044578","wikidata":"https://www.wikidata.org/wiki/Q727490","display_name":"Scalability","level":2,"score":0.6557324528694153},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6236627101898193},{"id":"https://openalex.org/C111030470","wikidata":"https://www.wikidata.org/wiki/Q1430460","display_name":"Curse of dimensionality","level":2,"score":0.6182475686073303},{"id":"https://openalex.org/C148483581","wikidata":"https://www.wikidata.org/wiki/Q446488","display_name":"Feature selection","level":2,"score":0.5911719799041748},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.5782498121261597},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.5140489339828491},{"id":"https://openalex.org/C98045186","wikidata":"https://www.wikidata.org/wiki/Q205663","display_name":"Process (computing)","level":2,"score":0.45281121134757996},{"id":"https://openalex.org/C111335779","wikidata":"https://www.wikidata.org/wiki/Q3454686","display_name":"Reduction (mathematics)","level":2,"score":0.4491385221481323},{"id":"https://openalex.org/C52622490","wikidata":"https://www.wikidata.org/wiki/Q1026626","display_name":"Feature extraction","level":2,"score":0.44518017768859863},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.43325936794281006},{"id":"https://openalex.org/C132525143","wikidata":"https://www.wikidata.org/wiki/Q141488","display_name":"Graph","level":2,"score":0.43122535943984985},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.4174753427505493},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.34883034229278564},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.18159714341163635},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.1376987099647522},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.0},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000098405","descriptor_name":"Dimensionality Reduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000098405","descriptor_name":"Dimensionality Reduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003704","descriptor_name":"Dementia","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D003704","descriptor_name":"Dementia","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1142/s012906572550042x","is_oa":false,"landing_page_url":"https://doi.org/10.1142/s012906572550042x","pdf_url":null,"source":{"id":"https://openalex.org/S197665576","display_name":"International Journal of Neural Systems","issn_l":"0129-0657","issn":["0129-0657","1793-6462"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319815","host_organization_name":"World Scientific","host_organization_lineage":["https://openalex.org/P4310319815"],"host_organization_lineage_names":["World Scientific"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Neural Systems","raw_type":"journal-article"},{"id":"pmid:40506829","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40506829","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of neural systems","raw_type":null},{"id":"pmh:oai:zenodo.org:17979477","is_oa":true,"landing_page_url":"https://doi.org/10.1142/S012906572550042X","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Neural Systems, 35(09), 2550042, (2025-09-01)","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:zenodo.org:17979477","is_oa":true,"landing_page_url":"https://doi.org/10.1142/S012906572550042X","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Neural Systems, 35(09), 2550042, (2025-09-01)","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"display_name":"Reduced inequalities","score":0.4699999988079071,"id":"https://metadata.un.org/sdg/10"}],"awards":[{"id":"https://openalex.org/G3625236165","display_name":null,"funder_award_id":"PEICTI 2021-2023","funder_id":"https://openalex.org/F4320322930","funder_display_name":"Ministerio de Ciencia e Innovaci\u00f3n"},{"id":"https://openalex.org/G367127313","display_name":null,"funder_award_id":"PID2023-151605OB-C22","funder_id":"https://openalex.org/F4320322930","funder_display_name":"Ministerio de Ciencia e Innovaci\u00f3n"},{"id":"https://openalex.org/G8782592523","display_name":null,"funder_award_id":"TED2021-131520B-C22","funder_id":"https://openalex.org/F4320322930","funder_display_name":"Ministerio de Ciencia e Innovaci\u00f3n"}],"funders":[{"id":"https://openalex.org/F4320322930","display_name":"Ministerio de Ciencia e Innovaci\u00f3n","ror":"https://ror.org/034900433"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":43,"referenced_works":["https://openalex.org/W607505555","https://openalex.org/W1976133119","https://openalex.org/W2024461202","https://openalex.org/W2044348081","https://openalex.org/W2053186076","https://openalex.org/W2124260444","https://openalex.org/W2145979309","https://openalex.org/W2150534249","https://openalex.org/W2292795565","https://openalex.org/W2588408640","https://openalex.org/W2606408532","https://openalex.org/W2612872092","https://openalex.org/W2771063166","https://openalex.org/W2883543619","https://openalex.org/W2898126478","https://openalex.org/W2934399013","https://openalex.org/W2936573766","https://openalex.org/W2943806423","https://openalex.org/W2963224980","https://openalex.org/W3003265726","https://openalex.org/W3013699712","https://openalex.org/W3034336123","https://openalex.org/W3092478740","https://openalex.org/W3108447748","https://openalex.org/W3113483010","https://openalex.org/W3128840207","https://openalex.org/W3144635834","https://openalex.org/W3165355909","https://openalex.org/W3210619801","https://openalex.org/W3212684309","https://openalex.org/W4205200154","https://openalex.org/W4206095984","https://openalex.org/W4294559022","https://openalex.org/W4308679051","https://openalex.org/W4317520064","https://openalex.org/W4361298490","https://openalex.org/W4385252239","https://openalex.org/W4386254041","https://openalex.org/W4387722547","https://openalex.org/W4388703849","https://openalex.org/W4391505627","https://openalex.org/W4392852805","https://openalex.org/W4399160231"],"related_works":["https://openalex.org/W1995622179","https://openalex.org/W1484111231","https://openalex.org/W4391160746","https://openalex.org/W1552543208","https://openalex.org/W2074396517","https://openalex.org/W2166963679","https://openalex.org/W2187269125","https://openalex.org/W1641615907","https://openalex.org/W3089231081","https://openalex.org/W2093956241"],"abstract_inverted_index":{"The":[0],"reduction":[1,85],"of":[2,18,33,44,101,111],"dimensionality":[3,59,84],"in":[4,15,67,98],"machine":[5],"learning":[6,105],"and":[7,25,42,64,91],"artificial":[8],"intelligence":[9],"problems":[10],"constitutes":[11],"a":[12,75,83],"pivotal":[13],"element":[14],"the":[16,31,40,99,108,113],"simplification":[17],"models,":[19,106],"significantly":[20],"enhancing":[21],"both":[22],"their":[23],"performance":[24],"execution":[26],"time.":[27],"This":[28,94],"process":[29],"enables":[30],"generation":[32],"results":[34],"more":[35],"rapidly":[36],"while":[37],"also":[38],"facilitating":[39],"scalability":[41],"optimization":[43],"systems":[45],"that":[46],"rely":[47],"on":[48,88],"such":[49],"models.":[50],"Two":[51],"primary":[52],"approaches":[53],"are":[54],"commonly":[55],"employed":[56],"to":[57],"achieve":[58],"reduction:":[60],"feature":[61,68,77],"selection-based":[62],"methods":[63],"those":[65],"grounded":[66],"extraction.":[69],"In":[70],"this":[71],"paper,":[72],"we":[73,81],"propose":[74],"distance-correlation":[76],"space,":[78],"upon":[79],"which":[80],"define":[82],"algorithm":[86],"based":[87],"space":[89],"transformations":[90],"graph":[92],"embeddings.":[93],"methodology":[95],"is":[96],"applied":[97],"context":[100],"dementia":[102],"diagnosis":[103],"through":[104],"with":[107],"overarching":[109],"objective":[110],"optimizing":[112],"diagnostic":[114],"process.":[115]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-03-27T05:58:40.876381","created_date":"2025-10-10T00:00:00"}