{"id":"https://openalex.org/W2020757483","doi":"https://doi.org/10.1142/s179396231350027x","title":"Finite element model to study the effect of exogenous buffer on calcium dynamics in dendritic spines","display_name":"Finite element model to study the effect of exogenous buffer on calcium dynamics in dendritic spines","publication_year":2013,"publication_date":"2013-09-12","ids":{"openalex":"https://openalex.org/W2020757483","doi":"https://doi.org/10.1142/s179396231350027x","mag":"2020757483"},"language":"en","primary_location":{"id":"doi:10.1142/s179396231350027x","is_oa":false,"landing_page_url":"https://doi.org/10.1142/s179396231350027x","pdf_url":null,"source":{"id":"https://openalex.org/S107361000","display_name":"Advances in Complex Systems","issn_l":"0219-5259","issn":["0219-5259","1793-6802","1793-9615","1793-9623"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319815","host_organization_name":"World Scientific","host_organization_lineage":["https://openalex.org/P4310319815"],"host_organization_lineage_names":["World Scientific"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Modeling, Simulation, and Scientific Computing","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047488540","display_name":"Amrita Jha","orcid":"https://orcid.org/0000-0001-5016-102X"},"institutions":[{"id":"https://openalex.org/I42014448","display_name":"Sardar Vallabhbhai National Institute of Technology Surat","ror":"https://ror.org/02y394t43","country_code":"IN","type":"education","lineage":["https://openalex.org/I42014448"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Amrita Jha","raw_affiliation_strings":["Department of Applied Mathematics and Humanities, S.V. National Institute of Technology, Surat, Gujarat-395007, India","Department of Applied Mathematics & Humanities, S. V. National Institute of Technology, Surat, Gujarat, 395007, India"],"affiliations":[{"raw_affiliation_string":"Department of Applied Mathematics and Humanities, S.V. National Institute of Technology, Surat, Gujarat-395007, India","institution_ids":["https://openalex.org/I42014448"]},{"raw_affiliation_string":"Department of Applied Mathematics & Humanities, S. V. National Institute of Technology, Surat, Gujarat, 395007, India","institution_ids":["https://openalex.org/I42014448"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5088033469","display_name":"Neeru Adlakha","orcid":"https://orcid.org/0000-0002-6717-8597"},"institutions":[{"id":"https://openalex.org/I42014448","display_name":"Sardar Vallabhbhai National Institute of Technology Surat","ror":"https://ror.org/02y394t43","country_code":"IN","type":"education","lineage":["https://openalex.org/I42014448"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Neeru Adlakha","raw_affiliation_strings":["Department of Applied Mathematics and Humanities, S.V. National Institute of Technology, Surat, Gujarat-395007, India","Department of Applied Mathematics & Humanities, S. V. National Institute of Technology, Surat, Gujarat, 395007, India"],"affiliations":[{"raw_affiliation_string":"Department of Applied Mathematics and Humanities, S.V. National Institute of Technology, Surat, Gujarat-395007, India","institution_ids":["https://openalex.org/I42014448"]},{"raw_affiliation_string":"Department of Applied Mathematics & Humanities, S. V. National Institute of Technology, Surat, Gujarat, 395007, India","institution_ids":["https://openalex.org/I42014448"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5047488540"],"corresponding_institution_ids":["https://openalex.org/I42014448"],"apc_list":null,"apc_paid":null,"fwci":0.423,"has_fulltext":false,"cited_by_count":33,"citation_normalized_percentile":{"value":0.58128459,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"05","issue":"02","first_page":"1350027","last_page":"1350027"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9983000159263611,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9983000159263611,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11686","display_name":"Dendrimers and Hyperbranched Polymers","score":0.994700014591217,"subfield":{"id":"https://openalex.org/subfields/2507","display_name":"Polymers and Plastics"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.9814000129699707,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dendritic-spine","display_name":"Dendritic spine","score":0.8287159204483032},{"id":"https://openalex.org/keywords/calcium","display_name":"Calcium","score":0.6136001944541931},{"id":"https://openalex.org/keywords/synapse","display_name":"Synapse","score":0.48031753301620483},{"id":"https://openalex.org/keywords/dynamics","display_name":"Dynamics (music)","score":0.4692299962043762},{"id":"https://openalex.org/keywords/dendritic-filopodia","display_name":"Dendritic filopodia","score":0.4496859908103943},{"id":"https://openalex.org/keywords/spine","display_name":"SPINE (molecular biology)","score":0.44440534710884094},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4300183057785034},{"id":"https://openalex.org/keywords/neuron","display_name":"Neuron","score":0.42858392000198364},{"id":"https://openalex.org/keywords/finite-element-method","display_name":"Finite element method","score":0.4146372675895691},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.4104578495025635},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.3666614890098572},{"id":"https://openalex.org/keywords/biophysics","display_name":"Biophysics","score":0.35360169410705566},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.3447915315628052},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.22505182027816772},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.21759817004203796},{"id":"https://openalex.org/keywords/cell-biology","display_name":"Cell biology","score":0.14031413197517395},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.12986597418785095},{"id":"https://openalex.org/keywords/structural-engineering","display_name":"Structural engineering","score":0.11508285999298096}],"concepts":[{"id":"https://openalex.org/C174884520","wikidata":"https://www.wikidata.org/wiki/Q902079","display_name":"Dendritic spine","level":3,"score":0.8287159204483032},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.6136001944541931},{"id":"https://openalex.org/C127445978","wikidata":"https://www.wikidata.org/wiki/Q187181","display_name":"Synapse","level":2,"score":0.48031753301620483},{"id":"https://openalex.org/C145912823","wikidata":"https://www.wikidata.org/wiki/Q113558","display_name":"Dynamics (music)","level":2,"score":0.4692299962043762},{"id":"https://openalex.org/C53250682","wikidata":"https://www.wikidata.org/wiki/Q5256674","display_name":"Dendritic filopodia","level":4,"score":0.4496859908103943},{"id":"https://openalex.org/C205383261","wikidata":"https://www.wikidata.org/wiki/Q7392570","display_name":"SPINE (molecular biology)","level":2,"score":0.44440534710884094},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4300183057785034},{"id":"https://openalex.org/C2778794669","wikidata":"https://www.wikidata.org/wiki/Q43054","display_name":"Neuron","level":2,"score":0.42858392000198364},{"id":"https://openalex.org/C135628077","wikidata":"https://www.wikidata.org/wiki/Q220184","display_name":"Finite element method","level":2,"score":0.4146372675895691},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.4104578495025635},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.3666614890098572},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.35360169410705566},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3447915315628052},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.22505182027816772},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.21759817004203796},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.14031413197517395},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.12986597418785095},{"id":"https://openalex.org/C66938386","wikidata":"https://www.wikidata.org/wiki/Q633538","display_name":"Structural engineering","level":1,"score":0.11508285999298096},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C148762608","wikidata":"https://www.wikidata.org/wiki/Q3748185","display_name":"Hippocampal formation","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1142/s179396231350027x","is_oa":false,"landing_page_url":"https://doi.org/10.1142/s179396231350027x","pdf_url":null,"source":{"id":"https://openalex.org/S107361000","display_name":"Advances in Complex Systems","issn_l":"0219-5259","issn":["0219-5259","1793-6802","1793-9615","1793-9623"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319815","host_organization_name":"World Scientific","host_organization_lineage":["https://openalex.org/P4310319815"],"host_organization_lineage_names":["World Scientific"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Modeling, Simulation, and Scientific Computing","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W1577778731","https://openalex.org/W1591593323","https://openalex.org/W1670760110","https://openalex.org/W1708200691","https://openalex.org/W1965773406","https://openalex.org/W1970111700","https://openalex.org/W1970578796","https://openalex.org/W1979169606","https://openalex.org/W1995702697","https://openalex.org/W2007135500","https://openalex.org/W2015908211","https://openalex.org/W2017245381","https://openalex.org/W2021235911","https://openalex.org/W2021285984","https://openalex.org/W2024048296","https://openalex.org/W2042934979","https://openalex.org/W2046509930","https://openalex.org/W2068904497","https://openalex.org/W2081172975","https://openalex.org/W2101473364","https://openalex.org/W2109889898","https://openalex.org/W2133973757","https://openalex.org/W2142672656","https://openalex.org/W2143477348","https://openalex.org/W2163172571","https://openalex.org/W2314109860","https://openalex.org/W2326565381","https://openalex.org/W2462465517","https://openalex.org/W2605254549","https://openalex.org/W4210641863"],"related_works":["https://openalex.org/W2153083261","https://openalex.org/W2091097296","https://openalex.org/W2171612971","https://openalex.org/W1996493542","https://openalex.org/W2151251384","https://openalex.org/W2041963605","https://openalex.org/W4285601116","https://openalex.org/W2169505641","https://openalex.org/W2096973741","https://openalex.org/W2045158358"],"abstract_inverted_index":{"Dendritic":[0],"spine":[1],"plays":[2],"an":[3,56],"important":[4],"role":[5],"in":[6,9,38,50,71,107,144],"calcium":[7,36,48,64,142],"regulation":[8],"a":[10,16,26,39,78,111],"neuron":[11,40],"cell.":[12],"It":[13],"serves":[14],"as":[15],"storage":[17],"site":[18],"for":[19,110,120],"synaptic":[20],"strength":[21],"and":[22,125],"receives":[23],"input":[24],"from":[25],"single":[27],"synapse":[28],"of":[29,77,83,122,138],"axon.":[30],"In":[31,53],"order":[32],"to":[33,45,61,67,103,134],"understand":[34,46],"the":[35,47,63,68,75,105,108,123,136],"dynamics":[37,49,65],"cell,":[41],"it":[42],"is":[43,118],"crucial":[44],"dendritic":[51,72,84,145],"spines.":[52,146],"this":[54],"paper,":[55],"attempt":[57],"has":[58,100],"been":[59,95,101,132],"made":[60],"study":[62,135],"due":[66],"exogenous":[69,139],"buffers,":[70],"spines":[73,85],"with":[74],"help":[76],"sectional":[79],"model.":[80],"The":[81,128],"compartments":[82],"are":[86],"discretized":[87],"using":[88],"triangular":[89],"elements.":[90],"Appropriate":[91],"boundary":[92],"conditions":[93],"have":[94,131],"framed.":[96],"Finite":[97],"element":[98],"method":[99],"employed":[102],"obtain":[104],"solution":[106],"region":[109],"two-dimensional":[112],"unsteady":[113],"state":[114],"case.":[115],"MATLAB":[116],"7.11":[117],"used":[119,133],"simulation":[121],"problem":[124],"numerical":[126,129],"computations.":[127],"results":[130],"effect":[137],"buffers":[140],"on":[141],"distribution":[143]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":7},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":4},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1}],"updated_date":"2026-04-05T17:49:38.594831","created_date":"2025-10-10T00:00:00"}