{"id":"https://openalex.org/W2085454989","doi":"https://doi.org/10.1142/s1469026802000750","title":"LOCAL SEARCH BY CONCENTRATION-CONTROLLED DNA COMPUTING","display_name":"LOCAL SEARCH BY CONCENTRATION-CONTROLLED DNA COMPUTING","publication_year":2002,"publication_date":"2002-12-01","ids":{"openalex":"https://openalex.org/W2085454989","doi":"https://doi.org/10.1142/s1469026802000750","mag":"2085454989"},"language":"en","primary_location":{"id":"doi:10.1142/s1469026802000750","is_oa":false,"landing_page_url":"https://doi.org/10.1142/s1469026802000750","pdf_url":null,"source":{"id":"https://openalex.org/S206936884","display_name":"International Journal of Computational Intelligence and Applications","issn_l":"1469-0268","issn":["1469-0268","1757-5885"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311754","host_organization_name":"Imperial College Press","host_organization_lineage":["https://openalex.org/P4310311754"],"host_organization_lineage_names":["Imperial College Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Computational Intelligence and Applications","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101572257","display_name":"Masahito Yamamoto","orcid":"https://orcid.org/0000-0002-7326-3691"},"institutions":[{"id":"https://openalex.org/I205349734","display_name":"Hokkaido University","ror":"https://ror.org/02e16g702","country_code":"JP","type":"education","lineage":["https://openalex.org/I205349734"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"MASAHITO YAMAMOTO","raw_affiliation_strings":["Graduate School of Engineering, Hokkaido University, North 13, West 8, Kita-ku, Sapporo 060-862, Japan","PRESTO, JST, Hokkaido University, North 13, West 8,  Kita-ku, Sapporo 060-8628, Japan","PRESTO, JST, Hokkaido University, North 13, West 8, Kita-ku, Sapporo 060-8628, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Engineering, Hokkaido University, North 13, West 8, Kita-ku, Sapporo 060-862, Japan","institution_ids":["https://openalex.org/I205349734"]},{"raw_affiliation_string":"PRESTO, JST, Hokkaido University, North 13, West 8,  Kita-ku, Sapporo 060-8628, Japan","institution_ids":["https://openalex.org/I205349734"]},{"raw_affiliation_string":"PRESTO, JST, Hokkaido University, North 13, West 8, Kita-ku, Sapporo 060-8628, Japan","institution_ids":["https://openalex.org/I205349734"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085165516","display_name":"Yumi Kawazoe","orcid":"https://orcid.org/0000-0002-7373-4633"},"institutions":[{"id":"https://openalex.org/I205349734","display_name":"Hokkaido University","ror":"https://ror.org/02e16g702","country_code":"JP","type":"education","lineage":["https://openalex.org/I205349734"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"YUMI KAWAZOE","raw_affiliation_strings":["Graduate School of Dental Medicine, Hokkaido University, North 13, West 8, Kita-ku, Sapporo 060-8628, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Dental Medicine, Hokkaido University, North 13, West 8, Kita-ku, Sapporo 060-8628, Japan","institution_ids":["https://openalex.org/I205349734"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043496932","display_name":"Azuma Ohuchi","orcid":null},"institutions":[{"id":"https://openalex.org/I205349734","display_name":"Hokkaido University","ror":"https://ror.org/02e16g702","country_code":"JP","type":"education","lineage":["https://openalex.org/I205349734"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"AZUMA OHUCHI","raw_affiliation_strings":["Graduate School of Engineering, Hokkaido University, North 13, West 8, Kita-ku, Sapporo 060-862, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Engineering, Hokkaido University, North 13, West 8, Kita-ku, Sapporo 060-862, Japan","institution_ids":["https://openalex.org/I205349734"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111969429","display_name":"Atsushi Kameda","orcid":null},"institutions":[{"id":"https://openalex.org/I4210086780","display_name":"Japan Science and Technology Agency","ror":"https://ror.org/00097mb19","country_code":"JP","type":"government","lineage":["https://openalex.org/I4210086780"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"ATSUSHI KAMEDA","raw_affiliation_strings":["Japan Science and Technology Cooperation (JST), Honmachi 4-1-8, Kawaguchi 332-0012, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Japan Science and Technology Cooperation (JST), Honmachi 4-1-8, Kawaguchi 332-0012, Japan","institution_ids":["https://openalex.org/I4210086780"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103136231","display_name":"Nobuo Matsuura","orcid":"https://orcid.org/0000-0001-5931-140X"},"institutions":[{"id":"https://openalex.org/I4210137853","display_name":"Toyota Motor Corporation (Japan)","ror":"https://ror.org/02zqm6r10","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210125472","https://openalex.org/I4210137853"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"NOBUO MATSUURA","raw_affiliation_strings":["TOYOTA Motor Corporation, 7 Teiho,  Teiho-cho, Toyota 471-8574, Japan","TOYOTA Motor Corporation, 7 Teiho, Teiho-cho, Toyota 471-8574, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"TOYOTA Motor Corporation, 7 Teiho,  Teiho-cho, Toyota 471-8574, Japan","institution_ids":["https://openalex.org/I4210137853"]},{"raw_affiliation_string":"TOYOTA Motor Corporation, 7 Teiho, Teiho-cho, Toyota 471-8574, Japan","institution_ids":["https://openalex.org/I4210137853"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019528844","display_name":"Toshikazu Shiba","orcid":null},"institutions":[{"id":"https://openalex.org/I4210133530","display_name":"Fujirebio (Japan)","ror":"https://ror.org/03eykgw84","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210133530"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"TOSHIKAZU SHIBA","raw_affiliation_strings":["Frontier Research Division, FUJIREBIO Inc., 51 Komiya, Hachioji, Tokyo 192-0031, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Frontier Research Division, FUJIREBIO Inc., 51 Komiya, Hachioji, Tokyo 192-0031, Japan","institution_ids":["https://openalex.org/I4210133530"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5101572257"],"corresponding_institution_ids":["https://openalex.org/I205349734"],"apc_list":null,"apc_paid":null,"fwci":0.6901,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.68457171,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"02","issue":"04","first_page":"447","last_page":"455"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12029","display_name":"DNA and Biological Computing","score":0.949400007724762,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12029","display_name":"DNA and Biological Computing","score":0.949400007724762,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7855899930000305},{"id":"https://openalex.org/keywords/dna-computing","display_name":"DNA computing","score":0.6964490413665771},{"id":"https://openalex.org/keywords/shortest-path-problem","display_name":"Shortest path problem","score":0.6055935621261597},{"id":"https://openalex.org/keywords/process","display_name":"Process (computing)","score":0.5218141078948975},{"id":"https://openalex.org/keywords/graph","display_name":"Graph","score":0.49159368872642517},{"id":"https://openalex.org/keywords/dna","display_name":"DNA","score":0.46490418910980225},{"id":"https://openalex.org/keywords/path","display_name":"Path (computing)","score":0.419961541891098},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.3883509039878845},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.3403419256210327},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.3167189955711365},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.18391278386116028},{"id":"https://openalex.org/keywords/computation","display_name":"Computation","score":0.16561421751976013},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.14537003636360168},{"id":"https://openalex.org/keywords/computer-network","display_name":"Computer network","score":0.08225202560424805},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.07866746187210083}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7855899930000305},{"id":"https://openalex.org/C82047324","wikidata":"https://www.wikidata.org/wiki/Q177126","display_name":"DNA computing","level":3,"score":0.6964490413665771},{"id":"https://openalex.org/C22590252","wikidata":"https://www.wikidata.org/wiki/Q1058754","display_name":"Shortest path problem","level":3,"score":0.6055935621261597},{"id":"https://openalex.org/C98045186","wikidata":"https://www.wikidata.org/wiki/Q205663","display_name":"Process (computing)","level":2,"score":0.5218141078948975},{"id":"https://openalex.org/C132525143","wikidata":"https://www.wikidata.org/wiki/Q141488","display_name":"Graph","level":2,"score":0.49159368872642517},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.46490418910980225},{"id":"https://openalex.org/C2777735758","wikidata":"https://www.wikidata.org/wiki/Q817765","display_name":"Path (computing)","level":2,"score":0.419961541891098},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.3883509039878845},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.3403419256210327},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.3167189955711365},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.18391278386116028},{"id":"https://openalex.org/C45374587","wikidata":"https://www.wikidata.org/wiki/Q12525525","display_name":"Computation","level":2,"score":0.16561421751976013},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.14537003636360168},{"id":"https://openalex.org/C31258907","wikidata":"https://www.wikidata.org/wiki/Q1301371","display_name":"Computer network","level":1,"score":0.08225202560424805},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.07866746187210083},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1142/s1469026802000750","is_oa":false,"landing_page_url":"https://doi.org/10.1142/s1469026802000750","pdf_url":null,"source":{"id":"https://openalex.org/S206936884","display_name":"International Journal of Computational Intelligence and Applications","issn_l":"1469-0268","issn":["1469-0268","1757-5885"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311754","host_organization_name":"Imperial College Press","host_organization_lineage":["https://openalex.org/P4310311754"],"host_organization_lineage_names":["Imperial College Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Computational Intelligence and Applications","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/17","display_name":"Partnerships for the goals","score":0.6100000143051147}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":2,"referenced_works":["https://openalex.org/W2117052822","https://openalex.org/W2578481235"],"related_works":["https://openalex.org/W2049083263","https://openalex.org/W2265877813","https://openalex.org/W4255246195","https://openalex.org/W2126256889","https://openalex.org/W2372042166","https://openalex.org/W2388931296","https://openalex.org/W2041198660","https://openalex.org/W2007792919","https://openalex.org/W2106373246","https://openalex.org/W130594705"],"abstract_inverted_index":{"Concentration-controlled":[0],"DNA":[1,24,62,87],"computing":[2,63],"is":[3,40,64,96],"presented":[4],"for":[5,10],"accomplishing":[6],"a":[7,14,57,65,89,102],"local":[8,58],"search":[9,59],"the":[11,21,31,37,43,54,73,81,93,99],"solution":[12],"of":[13,23,45,85,92,101],"shortest":[15],"path":[16],"problem.":[17],"In":[18,68],"this":[19],"method,":[20],"concentrations":[22,44,84],"representing":[25],"edges":[26,79],"are":[27,105],"determined":[28],"according":[29],"to":[30,50,70],"costs":[32,77],"on":[33,78],"edges,":[34],"and":[35,83,98],"then":[36],"hybridization":[38,55,94],"process":[39,95],"performed.":[41],"Since":[42],"hopeless":[46],"candidate":[47],"solutions":[48],"tend":[49],"be":[51],"small":[52],"after":[53],"process,":[56],"by":[60],"concentration-controlled":[61],"promising":[66],"approach.":[67],"order":[69],"discuss":[71],"about":[72],"relationship":[74],"between":[75],"given":[76],"in":[80],"graph":[82],"generated":[86],"paths,":[88],"simulation":[90],"model":[91],"used":[97],"results":[100],"laboratory":[103],"experiment":[104],"shown.":[106]},"counts_by_year":[],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2025-10-10T00:00:00"}