{"id":"https://openalex.org/W3210031271","doi":"https://doi.org/10.1142/s0219720021500347","title":"Clarifying real receptor binding site between coronavirus HCoV-HKU1 and 9-O-Ac-Sia based on molecular docking","display_name":"Clarifying real receptor binding site between coronavirus HCoV-HKU1 and 9-O-Ac-Sia based on molecular docking","publication_year":2021,"publication_date":"2021-10-28","ids":{"openalex":"https://openalex.org/W3210031271","doi":"https://doi.org/10.1142/s0219720021500347","mag":"3210031271","pmid":"https://pubmed.ncbi.nlm.nih.gov/35061973"},"language":"en","primary_location":{"id":"doi:10.1142/s0219720021500347","is_oa":true,"landing_page_url":"https://doi.org/10.1142/s0219720021500347","pdf_url":null,"source":{"id":"https://openalex.org/S155349577","display_name":"Journal of Bioinformatics and Computational Biology","issn_l":"0219-7200","issn":["0219-7200","1757-6334"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311754","host_organization_name":"Imperial College Press","host_organization_lineage":["https://openalex.org/P4310311754"],"host_organization_lineage_names":["Imperial College Press"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Bioinformatics and Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1142/s0219720021500347","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Xiaoyu Liu","orcid":null},"institutions":[{"id":"https://openalex.org/I44675526","display_name":"Shanghai Ocean University","ror":"https://ror.org/04n40zv07","country_code":"CN","type":"education","lineage":["https://openalex.org/I44675526"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoyu Liu","raw_affiliation_strings":["Department of Developmental Biology, College of Fisheries and Life Science, Shanghai Ocean University Shanghai 201306, P.\u00a0R.\u00a0China","National Pathogen Collection Center for Aquatic Animals, Ministry of Agriculture of China, Shanghai 201306, P.\u00a0R.\u00a0China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Developmental Biology, College of Fisheries and Life Science, Shanghai Ocean University Shanghai 201306, P.\u00a0R.\u00a0China","institution_ids":["https://openalex.org/I44675526"]},{"raw_affiliation_string":"National Pathogen Collection Center for Aquatic Animals, Ministry of Agriculture of China, Shanghai 201306, P.\u00a0R.\u00a0China","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Jingying Zhao","orcid":null},"institutions":[{"id":"https://openalex.org/I44675526","display_name":"Shanghai Ocean University","ror":"https://ror.org/04n40zv07","country_code":"CN","type":"education","lineage":["https://openalex.org/I44675526"]},{"id":"https://openalex.org/I66867065","display_name":"East China Normal University","ror":"https://ror.org/02n96ep67","country_code":"CN","type":"education","lineage":["https://openalex.org/I66867065"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jingying Zhao","raw_affiliation_strings":["Department of Developmental Biology, College of Fisheries and Life Science, Shanghai Ocean University Shanghai 201306, P.\u00a0R.\u00a0China","School of Physical Education & Health Care, East China Normal University, Shanghai 200241, P.\u00a0R.\u00a0China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Developmental Biology, College of Fisheries and Life Science, Shanghai Ocean University Shanghai 201306, P.\u00a0R.\u00a0China","institution_ids":["https://openalex.org/I44675526"]},{"raw_affiliation_string":"School of Physical Education & Health Care, East China Normal University, Shanghai 200241, P.\u00a0R.\u00a0China","institution_ids":["https://openalex.org/I66867065"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Sicong Li","orcid":null},"institutions":[{"id":"https://openalex.org/I44675526","display_name":"Shanghai Ocean University","ror":"https://ror.org/04n40zv07","country_code":"CN","type":"education","lineage":["https://openalex.org/I44675526"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Sicong Li","raw_affiliation_strings":["Department of Developmental Biology, College of Fisheries and Life Science, Shanghai Ocean University Shanghai 201306, P.\u00a0R.\u00a0China","National Pathogen Collection Center for Aquatic Animals, Ministry of Agriculture of China, Shanghai 201306, P.\u00a0R.\u00a0China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Developmental Biology, College of Fisheries and Life Science, Shanghai Ocean University Shanghai 201306, P.\u00a0R.\u00a0China","institution_ids":["https://openalex.org/I44675526"]},{"raw_affiliation_string":"National Pathogen Collection Center for Aquatic Animals, Ministry of Agriculture of China, Shanghai 201306, P.\u00a0R.\u00a0China","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Cai Wei","orcid":null},"institutions":[{"id":"https://openalex.org/I44675526","display_name":"Shanghai Ocean University","ror":"https://ror.org/04n40zv07","country_code":"CN","type":"education","lineage":["https://openalex.org/I44675526"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Cai Wei","raw_affiliation_strings":["Department of Developmental Biology, College of Fisheries and Life Science, Shanghai Ocean University Shanghai 201306, P.\u00a0R.\u00a0China","National Pathogen Collection Center for Aquatic Animals, Ministry of Agriculture of China, Shanghai 201306, P.\u00a0R.\u00a0China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Developmental Biology, College of Fisheries and Life Science, Shanghai Ocean University Shanghai 201306, P.\u00a0R.\u00a0China","institution_ids":["https://openalex.org/I44675526"]},{"raw_affiliation_string":"National Pathogen Collection Center for Aquatic Animals, Ministry of Agriculture of China, Shanghai 201306, P.\u00a0R.\u00a0China","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Shihang Wang","orcid":null},"institutions":[{"id":"https://openalex.org/I44675526","display_name":"Shanghai Ocean University","ror":"https://ror.org/04n40zv07","country_code":"CN","type":"education","lineage":["https://openalex.org/I44675526"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shihang Wang","raw_affiliation_strings":["Department of Developmental Biology, College of Fisheries and Life Science, Shanghai Ocean University Shanghai 201306, P.\u00a0R.\u00a0China","National Pathogen Collection Center for Aquatic Animals, Ministry of Agriculture of China, Shanghai 201306, P.\u00a0R.\u00a0China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Developmental Biology, College of Fisheries and Life Science, Shanghai Ocean University Shanghai 201306, P.\u00a0R.\u00a0China","institution_ids":["https://openalex.org/I44675526"]},{"raw_affiliation_string":"National Pathogen Collection Center for Aquatic Animals, Ministry of Agriculture of China, Shanghai 201306, P.\u00a0R.\u00a0China","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Xuanyu Xu","orcid":null},"institutions":[{"id":"https://openalex.org/I44675526","display_name":"Shanghai Ocean University","ror":"https://ror.org/04n40zv07","country_code":"CN","type":"education","lineage":["https://openalex.org/I44675526"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xuanyu Xu","raw_affiliation_strings":["Department of Developmental Biology, College of Fisheries and Life Science, Shanghai Ocean University Shanghai 201306, P.\u00a0R.\u00a0China","National Pathogen Collection Center for Aquatic Animals, Ministry of Agriculture of China, Shanghai 201306, P.\u00a0R.\u00a0China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Developmental Biology, College of Fisheries and Life Science, Shanghai Ocean University Shanghai 201306, P.\u00a0R.\u00a0China","institution_ids":["https://openalex.org/I44675526"]},{"raw_affiliation_string":"National Pathogen Collection Center for Aquatic Animals, Ministry of Agriculture of China, Shanghai 201306, P.\u00a0R.\u00a0China","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Yin Zheng","orcid":null},"institutions":[{"id":"https://openalex.org/I44675526","display_name":"Shanghai Ocean University","ror":"https://ror.org/04n40zv07","country_code":"CN","type":"education","lineage":["https://openalex.org/I44675526"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yin Zheng","raw_affiliation_strings":["Department of Developmental Biology, College of Fisheries and Life Science, Shanghai Ocean University Shanghai 201306, P.\u00a0R.\u00a0China","National Pathogen Collection Center for Aquatic Animals, Ministry of Agriculture of China, Shanghai 201306, P.\u00a0R.\u00a0China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Developmental Biology, College of Fisheries and Life Science, Shanghai Ocean University Shanghai 201306, P.\u00a0R.\u00a0China","institution_ids":["https://openalex.org/I44675526"]},{"raw_affiliation_string":"National Pathogen Collection Center for Aquatic Animals, Ministry of Agriculture of China, Shanghai 201306, P.\u00a0R.\u00a0China","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Xiangyu Deng","orcid":null},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiangyu Deng","raw_affiliation_strings":["Xiangya School of Public Health, Central South University, Changsha, Hunan 410078, P.\u00a0R.\u00a0China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Xiangya School of Public Health, Central South University, Changsha, Hunan 410078, P.\u00a0R.\u00a0China","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Wenliang Yuan","orcid":null},"institutions":[{"id":"https://openalex.org/I4210092870","display_name":"Jiaxing University","ror":"https://ror.org/00j2a7k55","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210092870"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenliang Yuan","raw_affiliation_strings":["College of Mathematics and Information Engineering, Jiaxing University, Jiaxing, Zhejiang 314033, P.\u00a0R.\u00a0China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Mathematics and Information Engineering, Jiaxing University, Jiaxing, Zhejiang 314033, P.\u00a0R.\u00a0China","institution_ids":["https://openalex.org/I4210092870"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Xiaomin Zeng","orcid":null},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaomin Zeng","raw_affiliation_strings":["Xiangya School of Public Health, Central South University, Changsha, Hunan 410078, P.\u00a0R.\u00a0China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Xiangya School of Public Health, Central South University, Changsha, Hunan 410078, P.\u00a0R.\u00a0China","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"last","author":{"id":null,"display_name":"Sihua Peng","orcid":null},"institutions":[{"id":"https://openalex.org/I44675526","display_name":"Shanghai Ocean University","ror":"https://ror.org/04n40zv07","country_code":"CN","type":"education","lineage":["https://openalex.org/I44675526"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Sihua Peng","raw_affiliation_strings":["Department of Developmental Biology, College of Fisheries and Life Science, Shanghai Ocean University Shanghai 201306, P.\u00a0R.\u00a0China","National Pathogen Collection Center for Aquatic Animals, Ministry of Agriculture of China, Shanghai 201306, P.\u00a0R.\u00a0China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Developmental Biology, College of Fisheries and Life Science, Shanghai Ocean University Shanghai 201306, P.\u00a0R.\u00a0China","institution_ids":["https://openalex.org/I44675526"]},{"raw_affiliation_string":"National Pathogen Collection Center for Aquatic Animals, Ministry of Agriculture of China, Shanghai 201306, P.\u00a0R.\u00a0China","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.14169683,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"20","issue":"01","first_page":"2150034","last_page":"2150034"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.9376999735832214,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.9376999735832214,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10041","display_name":"COVID-19 Clinical Research Studies","score":0.014999999664723873,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11495","display_name":"Animal Virus Infections Studies","score":0.008999999612569809,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dock","display_name":"DOCK","score":0.8901000022888184},{"id":"https://openalex.org/keywords/docking","display_name":"Docking (animal)","score":0.6437000036239624},{"id":"https://openalex.org/keywords/binding-site","display_name":"Binding site","score":0.5866000056266785},{"id":"https://openalex.org/keywords/coronavirus","display_name":"Coronavirus","score":0.48919999599456787},{"id":"https://openalex.org/keywords/sialic-acid","display_name":"Sialic acid","score":0.44190001487731934},{"id":"https://openalex.org/keywords/plasma-protein-binding","display_name":"Plasma protein binding","score":0.4108000099658966},{"id":"https://openalex.org/keywords/severe-acute-respiratory-syndrome-coronavirus-2","display_name":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)","score":0.3781999945640564},{"id":"https://openalex.org/keywords/receptor","display_name":"Receptor","score":0.361299991607666},{"id":"https://openalex.org/keywords/severe-acute-respiratory-syndrome-coronavirus","display_name":"Severe acute respiratory syndrome coronavirus","score":0.3474999964237213}],"concepts":[{"id":"https://openalex.org/C93073132","wikidata":"https://www.wikidata.org/wiki/Q24726581","display_name":"DOCK","level":2,"score":0.8901000022888184},{"id":"https://openalex.org/C41685203","wikidata":"https://www.wikidata.org/wiki/Q1974042","display_name":"Docking (animal)","level":2,"score":0.6437000036239624},{"id":"https://openalex.org/C107824862","wikidata":"https://www.wikidata.org/wiki/Q616005","display_name":"Binding site","level":2,"score":0.5866000056266785},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5627999901771545},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5228000283241272},{"id":"https://openalex.org/C2777648638","wikidata":"https://www.wikidata.org/wiki/Q57751738","display_name":"Coronavirus","level":5,"score":0.48919999599456787},{"id":"https://openalex.org/C2780115458","wikidata":"https://www.wikidata.org/wiki/Q419311","display_name":"Sialic acid","level":2,"score":0.44190001487731934},{"id":"https://openalex.org/C51639874","wikidata":"https://www.wikidata.org/wiki/Q167149","display_name":"Plasma protein binding","level":2,"score":0.4108000099658966},{"id":"https://openalex.org/C3007834351","wikidata":"https://www.wikidata.org/wiki/Q82069695","display_name":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)","level":5,"score":0.3781999945640564},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.37720000743865967},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.361299991607666},{"id":"https://openalex.org/C2910188402","wikidata":"https://www.wikidata.org/wiki/Q85438966","display_name":"Severe acute respiratory syndrome coronavirus","level":5,"score":0.3474999964237213},{"id":"https://openalex.org/C178910836","wikidata":"https://www.wikidata.org/wiki/Q2196961","display_name":"Molecular model","level":2,"score":0.34220001101493835},{"id":"https://openalex.org/C167625842","wikidata":"https://www.wikidata.org/wiki/Q899763","display_name":"Peptide sequence","level":3,"score":0.3418999910354614},{"id":"https://openalex.org/C25166345","wikidata":"https://www.wikidata.org/wiki/Q4914012","display_name":"Binding domain","level":3,"score":0.3416000008583069},{"id":"https://openalex.org/C36503486","wikidata":"https://www.wikidata.org/wiki/Q11235244","display_name":"Domain (mathematical analysis)","level":2,"score":0.33649998903274536},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.31470000743865967},{"id":"https://openalex.org/C2994376932","wikidata":"https://www.wikidata.org/wiki/Q735188","display_name":"Amino acid residue","level":4,"score":0.31459999084472656},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3116999864578247},{"id":"https://openalex.org/C47701112","wikidata":"https://www.wikidata.org/wiki/Q735188","display_name":"Protein structure","level":2,"score":0.31119999289512634},{"id":"https://openalex.org/C89611455","wikidata":"https://www.wikidata.org/wiki/Q6804646","display_name":"Mechanism (biology)","level":2,"score":0.30320000648498535},{"id":"https://openalex.org/C45484198","wikidata":"https://www.wikidata.org/wiki/Q827246","display_name":"Sequence alignment","level":4,"score":0.30309998989105225},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.302700012922287},{"id":"https://openalex.org/C169627665","wikidata":"https://www.wikidata.org/wiki/Q5767913","display_name":"Homology modeling","level":3,"score":0.29319998621940613},{"id":"https://openalex.org/C41183919","wikidata":"https://www.wikidata.org/wiki/Q423026","display_name":"Active site","level":3,"score":0.27549999952316284},{"id":"https://openalex.org/C74187038","wikidata":"https://www.wikidata.org/wiki/Q1418791","display_name":"Drug discovery","level":2,"score":0.26429998874664307}],"mesh":[{"descriptor_ui":"D000073640","descriptor_name":"Betacoronavirus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000073640","descriptor_name":"Betacoronavirus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000073640","descriptor_name":"Betacoronavirus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017934","descriptor_name":"Coronavirus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017934","descriptor_name":"Coronavirus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017934","descriptor_name":"Coronavirus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D062105","descriptor_name":"Molecular Docking Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D062105","descriptor_name":"Molecular Docking Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D062105","descriptor_name":"Molecular Docking Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064370","descriptor_name":"Spike Glycoprotein, Coronavirus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D064370","descriptor_name":"Spike Glycoprotein, Coronavirus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D064370","descriptor_name":"Spike Glycoprotein, Coronavirus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1142/s0219720021500347","is_oa":true,"landing_page_url":"https://doi.org/10.1142/s0219720021500347","pdf_url":null,"source":{"id":"https://openalex.org/S155349577","display_name":"Journal of Bioinformatics and Computational Biology","issn_l":"0219-7200","issn":["0219-7200","1757-6334"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311754","host_organization_name":"Imperial College Press","host_organization_lineage":["https://openalex.org/P4310311754"],"host_organization_lineage_names":["Imperial College Press"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Bioinformatics and Computational Biology","raw_type":"journal-article"},{"id":"pmid:35061973","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35061973","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of bioinformatics and computational biology","raw_type":null}],"best_oa_location":{"id":"doi:10.1142/s0219720021500347","is_oa":true,"landing_page_url":"https://doi.org/10.1142/s0219720021500347","pdf_url":null,"source":{"id":"https://openalex.org/S155349577","display_name":"Journal of Bioinformatics and Computational Biology","issn_l":"0219-7200","issn":["0219-7200","1757-6334"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311754","host_organization_name":"Imperial College Press","host_organization_lineage":["https://openalex.org/P4310311754"],"host_organization_lineage_names":["Imperial College Press"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Bioinformatics and Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320309612","display_name":"Natural Science Foundation of Shanghai","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W95293157","https://openalex.org/W1934043894","https://openalex.org/W1993577573","https://openalex.org/W2024506488","https://openalex.org/W2050456292","https://openalex.org/W2103981148","https://openalex.org/W2137268987","https://openalex.org/W2145943872","https://openalex.org/W2158534713","https://openalex.org/W2165926351","https://openalex.org/W2170933940","https://openalex.org/W2292700442","https://openalex.org/W2538584349","https://openalex.org/W2620083990","https://openalex.org/W2796346355","https://openalex.org/W2903899730","https://openalex.org/W2912436263","https://openalex.org/W2948622157"],"related_works":[],"abstract_inverted_index":{"HCoV-HKU1":[0,29,44,76,98],"is":[1,20,30,77],"a":[2,17],"[Formula:":[3],"see":[4],"text]-coronavirus":[5],"with":[6,62,68],"low":[7],"pathogenicity,":[8],"which":[9],"usually":[10],"leads":[11],"to":[12,56],"respiratory":[13],"diseases.":[14],"At":[15],"present,":[16],"controversial":[18],"issue":[19],"that":[21,72],"whether":[22],"the":[23,33,38,43,58,69,73,80,90,97,104,111],"receptor":[24],"binding":[25],"site":[26],"(RBS)":[27],"of":[28,75,96,106,113],"located":[31,78],"in":[32,42,79],"N-terminal":[34],"domain":[35,40],"(NTD)":[36],"or":[37],"C-terminal":[39],"(CTD)":[41],"S":[45],"protein.":[46],"To":[47],"address":[48],"this":[49],"issue,":[50],"we":[51],"used":[52],"molecular":[53,94],"docking":[54],"technology":[55],"dock":[57],"NTD":[59,81],"and":[60,93,110],"CTD":[61],"9-oxoacetylated":[63],"sialic":[64],"acid":[65,83],"(9-O-Ac-Sia),":[66],"respectively,":[67],"results":[70],"showing":[71],"RBS":[74],"(amino":[82],"residues":[84],"80-95,":[85],"25-32).":[86],"Our":[87],"findings":[88],"clarified":[89],"structural":[91],"basis":[92],"mechanism":[95],"infection,":[99],"providing":[100],"important":[101],"information":[102],"for":[103],"development":[105],"therapeutic":[107],"antibody":[108],"drugs":[109],"design":[112],"vaccines.":[114]},"counts_by_year":[],"updated_date":"2026-06-29T08:53:18.405633","created_date":"2021-11-08T00:00:00"}