{"id":"https://openalex.org/W2888169224","doi":"https://doi.org/10.1142/s0219720018500221","title":"A 2-approximation algorithm for the contig-based genomic scaffold filling problem","display_name":"A 2-approximation algorithm for the contig-based genomic scaffold filling problem","publication_year":2018,"publication_date":"2018-08-20","ids":{"openalex":"https://openalex.org/W2888169224","doi":"https://doi.org/10.1142/s0219720018500221","mag":"2888169224","pmid":"https://pubmed.ncbi.nlm.nih.gov/30616473"},"language":"en","primary_location":{"id":"doi:10.1142/s0219720018500221","is_oa":false,"landing_page_url":"https://doi.org/10.1142/s0219720018500221","pdf_url":null,"source":{"id":"https://openalex.org/S155349577","display_name":"Journal of Bioinformatics and Computational Biology","issn_l":"0219-7200","issn":["0219-7200","1757-6334"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311754","host_organization_name":"Imperial College Press","host_organization_lineage":["https://openalex.org/P4310311754"],"host_organization_lineage_names":["Imperial College Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Bioinformatics and Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101836304","display_name":"Haitao Jiang","orcid":"https://orcid.org/0000-0001-6892-5200"},"institutions":[{"id":"https://openalex.org/I80143920","display_name":"Shandong University of Science and Technology","ror":"https://ror.org/04gtjhw98","country_code":"CN","type":"education","lineage":["https://openalex.org/I80143920"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haitao Jiang","raw_affiliation_strings":["School of Computer Science and Technology, Shandong University, Jinan, Shandong, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science and Technology, Shandong University, Jinan, Shandong, P. R. China","institution_ids":["https://openalex.org/I80143920"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021514550","display_name":"Letu Qingge","orcid":"https://orcid.org/0000-0002-9745-9584"},"institutions":[{"id":"https://openalex.org/I23732399","display_name":"Montana State University","ror":"https://ror.org/02w0trx84","country_code":"US","type":"education","lineage":["https://openalex.org/I23732399","https://openalex.org/I4210126032"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Letu Qingge","raw_affiliation_strings":["Gianforte School of Computing, Montana State University, Bozeman, MT 59717, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gianforte School of Computing, Montana State University, Bozeman, MT 59717, USA","institution_ids":["https://openalex.org/I23732399"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101769221","display_name":"Daming Zhu","orcid":"https://orcid.org/0000-0001-9395-7247"},"institutions":[{"id":"https://openalex.org/I80143920","display_name":"Shandong University of Science and Technology","ror":"https://ror.org/04gtjhw98","country_code":"CN","type":"education","lineage":["https://openalex.org/I80143920"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Daming Zhu","raw_affiliation_strings":["School of Computer Science and Technology, Shandong University, Jinan, Shandong, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science and Technology, Shandong University, Jinan, Shandong, P. R. China","institution_ids":["https://openalex.org/I80143920"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5070925973","display_name":"Binhai Zhu","orcid":null},"institutions":[{"id":"https://openalex.org/I23732399","display_name":"Montana State University","ror":"https://ror.org/02w0trx84","country_code":"US","type":"education","lineage":["https://openalex.org/I23732399","https://openalex.org/I4210126032"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Binhai Zhu","raw_affiliation_strings":["Gianforte School of Computing, Montana State University, Bozeman, MT 59717, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gianforte School of Computing, Montana State University, Bozeman, MT 59717, USA","institution_ids":["https://openalex.org/I23732399"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5070925973"],"corresponding_institution_ids":["https://openalex.org/I23732399"],"apc_list":null,"apc_paid":null,"fwci":0.5375,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.73230778,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"16","issue":"06","first_page":"1850022","last_page":"1850022"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13664","display_name":"Genome Rearrangement Algorithms","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T13664","display_name":"Genome Rearrangement Algorithms","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12991","display_name":"Phytase and its Applications","score":0.9437999725341797,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/contig","display_name":"Contig","score":0.8532460927963257},{"id":"https://openalex.org/keywords/sequence","display_name":"Sequence (biology)","score":0.5408286452293396},{"id":"https://openalex.org/keywords/scaffold","display_name":"Scaffold","score":0.5287584662437439},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.5010628700256348},{"id":"https://openalex.org/keywords/combinatorics","display_name":"Combinatorics","score":0.4728063642978668},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.46922263503074646},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.4634193480014801},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.44793450832366943},{"id":"https://openalex.org/keywords/simple","display_name":"Simple (philosophy)","score":0.43968814611434937},{"id":"https://openalex.org/keywords/discrete-mathematics","display_name":"Discrete mathematics","score":0.32351556420326233},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.19426822662353516},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.17185723781585693},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.1366836428642273},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.0704660713672638}],"concepts":[{"id":"https://openalex.org/C59582021","wikidata":"https://www.wikidata.org/wiki/Q1128751","display_name":"Contig","level":4,"score":0.8532460927963257},{"id":"https://openalex.org/C2778112365","wikidata":"https://www.wikidata.org/wiki/Q3511065","display_name":"Sequence (biology)","level":2,"score":0.5408286452293396},{"id":"https://openalex.org/C89429830","wikidata":"https://www.wikidata.org/wiki/Q735710","display_name":"Scaffold","level":2,"score":0.5287584662437439},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.5010628700256348},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.4728063642978668},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.46922263503074646},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.4634193480014801},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.44793450832366943},{"id":"https://openalex.org/C2780586882","wikidata":"https://www.wikidata.org/wiki/Q7520643","display_name":"Simple (philosophy)","level":2,"score":0.43968814611434937},{"id":"https://openalex.org/C118615104","wikidata":"https://www.wikidata.org/wiki/Q121416","display_name":"Discrete mathematics","level":1,"score":0.32351556420326233},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.19426822662353516},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.17185723781585693},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1366836428642273},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0704660713672638},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020451","descriptor_name":"Contig Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020451","descriptor_name":"Contig Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020451","descriptor_name":"Contig Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1142/s0219720018500221","is_oa":false,"landing_page_url":"https://doi.org/10.1142/s0219720018500221","pdf_url":null,"source":{"id":"https://openalex.org/S155349577","display_name":"Journal of Bioinformatics and Computational Biology","issn_l":"0219-7200","issn":["0219-7200","1757-6334"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311754","host_organization_name":"Imperial College Press","host_organization_lineage":["https://openalex.org/P4310311754"],"host_organization_lineage_names":["Imperial College Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Bioinformatics and Computational Biology","raw_type":"journal-article"},{"id":"pmid:30616473","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30616473","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of bioinformatics and computational biology","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320322819","display_name":"Zhejiang Normal University","ror":"https://ror.org/01vevwk45"},{"id":"https://openalex.org/F4320322927","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W18205210","https://openalex.org/W173661187","https://openalex.org/W1793987388","https://openalex.org/W1831121666","https://openalex.org/W1968943918","https://openalex.org/W1982055477","https://openalex.org/W1997993719","https://openalex.org/W2008289995","https://openalex.org/W2011039300","https://openalex.org/W2014286596","https://openalex.org/W2019300909","https://openalex.org/W2030886449","https://openalex.org/W2068187851","https://openalex.org/W2080347313","https://openalex.org/W2083215220","https://openalex.org/W2111945870","https://openalex.org/W2149628296","https://openalex.org/W2157529519","https://openalex.org/W2160388718","https://openalex.org/W2165336044","https://openalex.org/W2165795500","https://openalex.org/W2567911648","https://openalex.org/W2605161051","https://openalex.org/W2669318290"],"related_works":["https://openalex.org/W2015535546","https://openalex.org/W1994449010","https://openalex.org/W2074936491","https://openalex.org/W1545755951","https://openalex.org/W2069489638","https://openalex.org/W2044103084","https://openalex.org/W2020006618","https://openalex.org/W4381279187","https://openalex.org/W2115108201","https://openalex.org/W2108742089"],"abstract_inverted_index":{"The":[0,12,55],"genomic":[1,102],"scaffold":[2,86,103,113],"filling":[3,16,104],"problem":[4,13,56,105],"has":[5],"attracted":[6],"a":[7,31,61,85,92,112,157,164],"lot":[8],"of":[9,42,80,94,138],"attention":[10],"recently.":[11],"is":[14,53,57,71,87,117,133],"on":[15],"an":[17],"incomplete":[18],"sequence":[19,66],"(scaffold)":[20],"[Formula:":[21,25,35,46,50,68,114,142,149],"see":[22,26,36,47,51,69,115,143,150],"text]":[23,48,52,70,116,144],"into":[24],"text],":[27,37],"with":[28],"respect":[29],"to":[30,134],"complete":[32],"reference":[33],"genome":[34,148],"such":[38],"that":[39],"the":[40,65,81,101,119,128,131,136,146],"number":[41,137],"common/shared":[43],"adjacencies":[44,140],"between":[45,127,141],"and":[49,59,75,130,145],"maximized.":[54],"NP-complete,":[58],"admits":[60],"constant-factor":[62],"approximation.":[63],"However,":[64],"input":[67],"not":[72,77],"quite":[73],"practical":[74],"does":[76],"fit":[78],"most":[79],"real":[82],"datasets":[83],"(where":[84],"more":[88],"often":[89],"given":[90],"as":[91],"list":[93],"contigs).":[95],"In":[96],"this":[97,108,153],"paper,":[98],"we":[99,155,161],"revisit":[100],"by":[106],"considering":[107],"important":[109],"case":[110],"when":[111],"given,":[118],"missing":[120],"genes":[121],"can":[122],"only":[123],"be":[124],"inserted":[125],"in":[126],"contigs,":[129],"objective":[132],"maximize":[135],"common":[139],"filled":[147],"text].":[151],"For":[152],"problem,":[154],"present":[156,163],"simple":[158],"NP-completeness":[159],"proof,":[160],"then":[162],"factor-2":[165],"approximation":[166],"algorithm.":[167]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1}],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2025-10-10T00:00:00"}