{"id":"https://openalex.org/W2254068784","doi":"https://doi.org/10.1142/s0219720016500086","title":"Prediction of protein\u2013protein interaction network using a multi-objective optimization approach","display_name":"Prediction of protein\u2013protein interaction network using a multi-objective optimization approach","publication_year":2015,"publication_date":"2015-12-15","ids":{"openalex":"https://openalex.org/W2254068784","doi":"https://doi.org/10.1142/s0219720016500086","mag":"2254068784","pmid":"https://pubmed.ncbi.nlm.nih.gov/26846814"},"language":"en","primary_location":{"id":"doi:10.1142/s0219720016500086","is_oa":false,"landing_page_url":"https://doi.org/10.1142/s0219720016500086","pdf_url":null,"source":{"id":"https://openalex.org/S155349577","display_name":"Journal of Bioinformatics and Computational Biology","issn_l":"0219-7200","issn":["0219-7200","1757-6334"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311754","host_organization_name":"Imperial College Press","host_organization_lineage":["https://openalex.org/P4310311754"],"host_organization_lineage_names":["Imperial College Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Bioinformatics and Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103924685","display_name":"Archana Chowdhury","orcid":null},"institutions":[{"id":"https://openalex.org/I170979836","display_name":"Jadavpur University","ror":"https://ror.org/02af4h012","country_code":"IN","type":"education","lineage":["https://openalex.org/I170979836"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Archana Chowdhury","raw_affiliation_strings":["Artificial Intelligence Laboratory, Department of Electronics and Telecommunication Engineering, Jadavpur University, Kolkata, India"],"affiliations":[{"raw_affiliation_string":"Artificial Intelligence Laboratory, Department of Electronics and Telecommunication Engineering, Jadavpur University, Kolkata, India","institution_ids":["https://openalex.org/I170979836"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102829523","display_name":"Pratyusha Rakshit","orcid":"https://orcid.org/0000-0001-7350-2958"},"institutions":[{"id":"https://openalex.org/I170979836","display_name":"Jadavpur University","ror":"https://ror.org/02af4h012","country_code":"IN","type":"education","lineage":["https://openalex.org/I170979836"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Pratyusha Rakshit","raw_affiliation_strings":["Artificial Intelligence Laboratory, Department of Electronics and Telecommunication Engineering, Jadavpur University, Kolkata, India"],"affiliations":[{"raw_affiliation_string":"Artificial Intelligence Laboratory, Department of Electronics and Telecommunication Engineering, Jadavpur University, Kolkata, India","institution_ids":["https://openalex.org/I170979836"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011939964","display_name":"Amit Konar","orcid":"https://orcid.org/0000-0002-9474-5956"},"institutions":[{"id":"https://openalex.org/I170979836","display_name":"Jadavpur University","ror":"https://ror.org/02af4h012","country_code":"IN","type":"education","lineage":["https://openalex.org/I170979836"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Amit Konar","raw_affiliation_strings":["Artificial Intelligence Laboratory, Department of Electronics and Telecommunication Engineering, Jadavpur University, Kolkata, India"],"affiliations":[{"raw_affiliation_string":"Artificial Intelligence Laboratory, Department of Electronics and Telecommunication Engineering, Jadavpur University, Kolkata, India","institution_ids":["https://openalex.org/I170979836"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5103924685"],"corresponding_institution_ids":["https://openalex.org/I170979836"],"apc_list":null,"apc_paid":null,"fwci":0.4376,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.65827416,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":96},"biblio":{"volume":"14","issue":"03","first_page":"1650008","last_page":"1650008"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9980999827384949,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9979000091552734,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5097252726554871},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4312772750854492},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.3737439215183258},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.35645103454589844},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.22455841302871704}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5097252726554871},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4312772750854492},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.3737439215183258},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.35645103454589844},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.22455841302871704}],"mesh":[{"descriptor_ui":"D000072417","descriptor_name":"Protein Domains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000072417","descriptor_name":"Protein Domains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000072417","descriptor_name":"Protein Domains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D025941","descriptor_name":"Protein Interaction Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D025941","descriptor_name":"Protein Interaction Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D025941","descriptor_name":"Protein Interaction Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D029701","descriptor_name":"Saccharomyces cerevisiae Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D029701","descriptor_name":"Saccharomyces cerevisiae Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D029701","descriptor_name":"Saccharomyces cerevisiae Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D063990","descriptor_name":"Gene Ontology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063990","descriptor_name":"Gene Ontology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063990","descriptor_name":"Gene Ontology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1142/s0219720016500086","is_oa":false,"landing_page_url":"https://doi.org/10.1142/s0219720016500086","pdf_url":null,"source":{"id":"https://openalex.org/S155349577","display_name":"Journal of Bioinformatics and Computational Biology","issn_l":"0219-7200","issn":["0219-7200","1757-6334"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311754","host_organization_name":"Imperial College Press","host_organization_lineage":["https://openalex.org/P4310311754"],"host_organization_lineage_names":["Imperial College Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Bioinformatics and Computational Biology","raw_type":"journal-article"},{"id":"pmid:26846814","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26846814","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of bioinformatics and computational biology","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Life in Land","score":0.7400000095367432,"id":"https://metadata.un.org/sdg/15"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320320977","display_name":"Flinders University","ror":"https://ror.org/01kpzv902"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":39,"referenced_works":["https://openalex.org/W59676034","https://openalex.org/W202856896","https://openalex.org/W1523741643","https://openalex.org/W1647597862","https://openalex.org/W1918391659","https://openalex.org/W1972807714","https://openalex.org/W1975906723","https://openalex.org/W1977186059","https://openalex.org/W1978763597","https://openalex.org/W1984765576","https://openalex.org/W1989034333","https://openalex.org/W2024883193","https://openalex.org/W2037036397","https://openalex.org/W2040074453","https://openalex.org/W2050583899","https://openalex.org/W2054291744","https://openalex.org/W2078336808","https://openalex.org/W2080922074","https://openalex.org/W2084619201","https://openalex.org/W2085963663","https://openalex.org/W2096358531","https://openalex.org/W2102221598","https://openalex.org/W2107213743","https://openalex.org/W2116661285","https://openalex.org/W2121343862","https://openalex.org/W2122836610","https://openalex.org/W2123808725","https://openalex.org/W2132160618","https://openalex.org/W2132582966","https://openalex.org/W2133138357","https://openalex.org/W2133654213","https://openalex.org/W2136957665","https://openalex.org/W2145427519","https://openalex.org/W2146312020","https://openalex.org/W2163485494","https://openalex.org/W2163630575","https://openalex.org/W2166994421","https://openalex.org/W2250718735","https://openalex.org/W4210400672"],"related_works":["https://openalex.org/W2961085424","https://openalex.org/W4306674287","https://openalex.org/W3046775127","https://openalex.org/W3107602296","https://openalex.org/W3170094116","https://openalex.org/W4386462264","https://openalex.org/W4313488044","https://openalex.org/W3209574120","https://openalex.org/W4312192474","https://openalex.org/W4210805261"],"abstract_inverted_index":{"Protein-Protein":[0],"Interactions":[1],"(PPIs)":[2],"are":[3],"very":[4],"important":[5],"as":[6],"they":[7],"coordinate":[8],"almost":[9],"all":[10],"cellular":[11],"processes.":[12],"This":[13],"paper":[14],"attempts":[15],"to":[16,56,111],"formulate":[17],"PPI":[18,79],"prediction":[19,80],"problem":[20,62],"in":[21],"a":[22],"multi-objective":[23],"optimization":[24,61],"framework.":[25],"The":[26,59],"scoring":[27],"functions":[28],"for":[29],"the":[30,42,47,53,66,77],"trial":[31],"solution":[32],"deal":[33],"with":[34,70,102,109],"simultaneous":[35],"maximization":[36],"of":[37,41,49,52],"functional":[38],"similarity,":[39],"strength":[40],"domain":[43],"interaction":[44],"profiles,":[45],"and":[46,105,114],"number":[48],"common":[50],"neighbors":[51],"proteins":[54],"predicted":[55],"be":[57],"interacting.":[58],"above":[60],"is":[63],"solved":[64],"using":[65],"proposed":[67,78],"Firefly":[68],"Algorithm":[69],"Nondominated":[71],"Sorting.":[72],"Experiments":[73],"undertaken":[74],"reveal":[75],"that":[76],"technique":[81],"outperforms":[82],"existing":[83],"methods,":[84],"including":[85],"gene":[86],"ontology-based":[87],"Relative":[88],"Specific":[89],"Similarity,":[90],"multi-domain-based":[91],"Domain":[92],"Cohesion":[93],"Coupling":[94],"method,":[95,100],"domain-based":[96],"Random":[97],"Decision":[98],"Forest":[99],"Bagging":[101],"REP":[103],"Tree,":[104],"evolutionary/swarm":[106],"algorithm-based":[107],"approaches,":[108],"respect":[110],"sensitivity,":[112],"specificity,":[113],"F1":[115],"score.":[116]},"counts_by_year":[{"year":2018,"cited_by_count":2},{"year":2016,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}