{"id":"https://openalex.org/W2000031014","doi":"https://doi.org/10.1142/s021972001241003x","title":"SHEEP: A TOOL FOR DESCRIPTION OF \u03b2-SHEETS IN PROTEIN 3D STRUCTURES","display_name":"SHEEP: A TOOL FOR DESCRIPTION OF \u03b2-SHEETS IN PROTEIN 3D STRUCTURES","publication_year":2012,"publication_date":"2012-01-13","ids":{"openalex":"https://openalex.org/W2000031014","doi":"https://doi.org/10.1142/s021972001241003x","mag":"2000031014","pmid":"https://pubmed.ncbi.nlm.nih.gov/22809339"},"language":"en","primary_location":{"id":"doi:10.1142/s021972001241003x","is_oa":false,"landing_page_url":"https://doi.org/10.1142/s021972001241003x","pdf_url":null,"source":{"id":"https://openalex.org/S155349577","display_name":"Journal of Bioinformatics and Computational Biology","issn_l":"0219-7200","issn":["0219-7200","1757-6334"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311754","host_organization_name":"Imperial College Press","host_organization_lineage":["https://openalex.org/P4310311754"],"host_organization_lineage_names":["Imperial College Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Bioinformatics and Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041482452","display_name":"Evgeniy Aksianov","orcid":null},"institutions":[{"id":"https://openalex.org/I19880235","display_name":"Lomonosov Moscow State University","ror":"https://ror.org/010pmpe69","country_code":"RU","type":"education","lineage":["https://openalex.org/I19880235"]}],"countries":["RU"],"is_corresponding":true,"raw_author_name":"EVGENIY AKSIANOV","raw_affiliation_strings":["Belozersky Institute of Physico-Chemical Biology, Moscow State University, Leninskie Gory 1-40, Moscow 119991, Russia"],"affiliations":[{"raw_affiliation_string":"Belozersky Institute of Physico-Chemical Biology, Moscow State University, Leninskie Gory 1-40, Moscow 119991, Russia","institution_ids":["https://openalex.org/I19880235"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5056758947","display_name":"Andrei V. Alexeevski","orcid":"https://orcid.org/0000-0001-7939-9939"},"institutions":[{"id":"https://openalex.org/I4210121062","display_name":"Research Institute for System Studies","ror":"https://ror.org/02smvmz76","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210097085","https://openalex.org/I4210121062"]},{"id":"https://openalex.org/I19880235","display_name":"Lomonosov Moscow State University","ror":"https://ror.org/010pmpe69","country_code":"RU","type":"education","lineage":["https://openalex.org/I19880235"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"ANDREI ALEXEEVSKI","raw_affiliation_strings":["Department of Bioengineering and Bioinformatics & Belozersky Institute of Physico-Chemical, Biology, Moscow State University, Leninskie Gory 1-37 & 1-40, Moscow 119991, Russia","Scientific Research Institute for System Studies (NIISI RAN), Moscow, Russia"],"affiliations":[{"raw_affiliation_string":"Department of Bioengineering and Bioinformatics & Belozersky Institute of Physico-Chemical, Biology, Moscow State University, Leninskie Gory 1-37 & 1-40, Moscow 119991, Russia","institution_ids":["https://openalex.org/I19880235"]},{"raw_affiliation_string":"Scientific Research Institute for System Studies (NIISI RAN), Moscow, Russia","institution_ids":["https://openalex.org/I4210121062"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5041482452"],"corresponding_institution_ids":["https://openalex.org/I19880235"],"apc_list":null,"apc_paid":null,"fwci":0.1313,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.5025786,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"10","issue":"02","first_page":"1241003","last_page":"1241003"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9937999844551086,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/beta-sheet","display_name":"Beta sheet","score":0.6638472676277161},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.5202442407608032},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.49504008889198303},{"id":"https://openalex.org/keywords/protein-structure","display_name":"Protein structure","score":0.47516295313835144},{"id":"https://openalex.org/keywords/domain","display_name":"Domain (mathematical analysis)","score":0.473163902759552},{"id":"https://openalex.org/keywords/structural-classification-of-proteins-database","display_name":"Structural Classification of Proteins database","score":0.4299502968788147},{"id":"https://openalex.org/keywords/structural-alignment","display_name":"Structural alignment","score":0.42168694734573364},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.3039044737815857},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.19607800245285034},{"id":"https://openalex.org/keywords/sequence-alignment","display_name":"Sequence alignment","score":0.18144741654396057}],"concepts":[{"id":"https://openalex.org/C159547669","wikidata":"https://www.wikidata.org/wiki/Q283449","display_name":"Beta sheet","level":3,"score":0.6638472676277161},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.5202442407608032},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.49504008889198303},{"id":"https://openalex.org/C47701112","wikidata":"https://www.wikidata.org/wiki/Q735188","display_name":"Protein structure","level":2,"score":0.47516295313835144},{"id":"https://openalex.org/C36503486","wikidata":"https://www.wikidata.org/wiki/Q11235244","display_name":"Domain (mathematical analysis)","level":2,"score":0.473163902759552},{"id":"https://openalex.org/C58773245","wikidata":"https://www.wikidata.org/wiki/Q4832556","display_name":"Structural Classification of Proteins database","level":3,"score":0.4299502968788147},{"id":"https://openalex.org/C4668613","wikidata":"https://www.wikidata.org/wiki/Q4116110","display_name":"Structural alignment","level":5,"score":0.42168694734573364},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.3039044737815857},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.19607800245285034},{"id":"https://openalex.org/C45484198","wikidata":"https://www.wikidata.org/wiki/Q827246","display_name":"Sequence alignment","level":4,"score":0.18144741654396057},{"id":"https://openalex.org/C167625842","wikidata":"https://www.wikidata.org/wiki/Q899763","display_name":"Peptide sequence","level":3,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006860","descriptor_name":"Hydrogen Bonding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006860","descriptor_name":"Hydrogen Bonding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006860","descriptor_name":"Hydrogen Bonding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017433","descriptor_name":"Protein Structure, Secondary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017433","descriptor_name":"Protein Structure, Secondary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017433","descriptor_name":"Protein Structure, Secondary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1142/s021972001241003x","is_oa":false,"landing_page_url":"https://doi.org/10.1142/s021972001241003x","pdf_url":null,"source":{"id":"https://openalex.org/S155349577","display_name":"Journal of Bioinformatics and Computational Biology","issn_l":"0219-7200","issn":["0219-7200","1757-6334"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311754","host_organization_name":"Imperial College Press","host_organization_lineage":["https://openalex.org/P4310311754"],"host_organization_lineage_names":["Imperial College Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Bioinformatics and Computational Biology","raw_type":"journal-article"},{"id":"pmid:22809339","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22809339","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of bioinformatics and computational biology","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321079","display_name":"Russian Foundation for Basic Research","ror":"https://ror.org/02mh1ke95"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W2008708467","https://openalex.org/W2026258231","https://openalex.org/W2085277871","https://openalex.org/W2107521254","https://openalex.org/W2108067237","https://openalex.org/W2113381945","https://openalex.org/W2115312817","https://openalex.org/W2117898316","https://openalex.org/W2138422173","https://openalex.org/W2138562699","https://openalex.org/W2141920771","https://openalex.org/W2145780585","https://openalex.org/W2151960293","https://openalex.org/W4235333566"],"related_works":["https://openalex.org/W4220937102","https://openalex.org/W2075451741","https://openalex.org/W2118652015","https://openalex.org/W1989756167","https://openalex.org/W4235583582","https://openalex.org/W2141805605","https://openalex.org/W2053526761","https://openalex.org/W1988384104","https://openalex.org/W2613371097","https://openalex.org/W2014499409"],"abstract_inverted_index":{"The":[0,135,166],"description":[1,27,57],"of":[2,14,28,52,58,133,148,163],"a":[3,7,50,101,104,173],"protein":[4,38,157,175],"fold":[5],"is":[6,32,44,61,137],"hard":[8],"problem":[9],"due":[10,69],"to":[11,42,70,169],"significant":[12],"variability":[13,72],"main":[15],"structural":[16,30,59,191],"units,":[17],"\u03b2-sheets":[18,65,71,87,113,171,188],"and":[19,21,56,76,93,96,125,154,160,189],"\u03b1-helixes,":[20],"their":[22,190],"mutual":[23],"arrangements.":[24],"An":[25],"adequate":[26],"the":[29,98,131],"units":[31,60],"an":[33,81],"important":[34],"step":[35],"in":[36,49,74,139,172],"objective":[37],"structure":[39],"classification,":[40],"which":[41],"date":[43],"based":[45],"on":[46],"expert":[47],"judgment":[48],"number":[51],"cases.":[53],"Explicit":[54],"determination":[55,132],"more":[62],"complicated":[63],"for":[64,67,130,145],"than":[66,115],"\u03b1-helixes":[68],"both":[73],"composition":[75],"geometry.":[77],"We":[78],"have":[79],"developed":[80],"algorithm":[82,136],"that":[83],"can":[84],"significantly":[85],"modify":[86],"detected":[88],"by":[89],"commonly":[90],"used":[91],"DSSP":[92],"Stride":[94],"algorithms":[95],"represent":[97],"result":[99],"as":[100,119,180,182],"\"\u03b2-sheet":[102],"map,\"":[103],"table":[105],"describing":[106],"certain":[107],"\u03b2-sheet":[108,178],"features.":[109,192],"In":[110],"our":[111],"approach,":[112],"(rather":[114],"\u03b2-strands)":[116],"are":[117,128],"considered":[118],"holistic":[120],"objects.":[121],"Both":[122],"hydrogen":[123],"bonds":[124],"geometrical":[126],"restrains":[127],"explored":[129],"\u03b2-sheets.":[134],"implemented":[138],"SheeP":[140],"program.":[141],"It":[142],"was":[143],"tested":[144],"prediction":[146],"architectures":[147],"domains":[149],"from":[150],"93":[151],"well-defined":[152],"all-\u03b2":[153],"\u03b1/\u03b2":[155],"SCOP":[156],"domain":[158],"families,":[159],"showed":[161],"93%":[162],"correct":[164],"results.":[165],"Web-service":[167],"allows":[168],"detect":[170],"given":[174],"structure,":[176],"visualize":[177],"maps,":[179],"well":[181],"input":[183],"three-dimensional":[184],"structures":[185],"with":[186],"highlighted":[187]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}