{"id":"https://openalex.org/W4386806836","doi":"https://doi.org/10.1142/s0219691323500479","title":"Automatic SARS-CoV-2 segmentation in electron microscopy based on few-shot learning","display_name":"Automatic SARS-CoV-2 segmentation in electron microscopy based on few-shot learning","publication_year":2023,"publication_date":"2023-09-16","ids":{"openalex":"https://openalex.org/W4386806836","doi":"https://doi.org/10.1142/s0219691323500479"},"language":"en","primary_location":{"id":"doi:10.1142/s0219691323500479","is_oa":false,"landing_page_url":"https://doi.org/10.1142/s0219691323500479","pdf_url":null,"source":{"id":"https://openalex.org/S56986848","display_name":"International Journal of Wavelets Multiresolution and Information Processing","issn_l":"0219-6913","issn":["0219-6913","1793-690X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319815","host_organization_name":"World Scientific","host_organization_lineage":["https://openalex.org/P4310319815"],"host_organization_lineage_names":["World Scientific"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Wavelets, Multiresolution and Information Processing","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101062897","display_name":"Chi Xiao","orcid":null},"institutions":[{"id":"https://openalex.org/I20942203","display_name":"Hainan University","ror":"https://ror.org/03q648j11","country_code":"CN","type":"education","lineage":["https://openalex.org/I20942203"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chi Xiao","raw_affiliation_strings":["Key Laboratory of Biomedical Engineering of Hainan Province, School of Biomedical Engineering, Hainan University, Haikou 570228, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Biomedical Engineering of Hainan Province, School of Biomedical Engineering, Hainan University, Haikou 570228, P. R. China","institution_ids":["https://openalex.org/I20942203"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101916404","display_name":"Xiaoyu Xia","orcid":"https://orcid.org/0000-0003-3526-3217"},"institutions":[{"id":"https://openalex.org/I162868743","display_name":"Tianjin University","ror":"https://ror.org/012tb2g32","country_code":"CN","type":"education","lineage":["https://openalex.org/I162868743"]},{"id":"https://openalex.org/I5740404","display_name":"Tianjin Medical University","ror":"https://ror.org/02mh8wx89","country_code":"CN","type":"education","lineage":["https://openalex.org/I5740404"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoyu Xia","raw_affiliation_strings":["Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin 300072, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin 300072, P. R. China","institution_ids":["https://openalex.org/I5740404","https://openalex.org/I162868743"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102556779","display_name":"Shunhao Xu","orcid":null},"institutions":[{"id":"https://openalex.org/I4800084","display_name":"Southwest Jiaotong University","ror":"https://ror.org/00hn7w693","country_code":"CN","type":"education","lineage":["https://openalex.org/I4800084"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shunhao Xu","raw_affiliation_strings":["School of Information Science and Technology, Southwest Jiaotong University, Chengdu 610031, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Information Science and Technology, Southwest Jiaotong University, Chengdu 610031, P. R. China","institution_ids":["https://openalex.org/I4800084"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001364222","display_name":"Qilin Huang","orcid":"https://orcid.org/0000-0001-5107-215X"},"institutions":[{"id":"https://openalex.org/I20942203","display_name":"Hainan University","ror":"https://ror.org/03q648j11","country_code":"CN","type":"education","lineage":["https://openalex.org/I20942203"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qilin Huang","raw_affiliation_strings":["School of Information and Communication Engineering, Hainan University, Haikou 570228, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Information and Communication Engineering, Hainan University, Haikou 570228, P. R. China","institution_ids":["https://openalex.org/I20942203"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101296040","display_name":"Hao Xiao","orcid":null},"institutions":[{"id":"https://openalex.org/I173759888","display_name":"Hunan Normal University","ror":"https://ror.org/053w1zy07","country_code":"CN","type":"education","lineage":["https://openalex.org/I173759888"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hao Xiao","raw_affiliation_strings":["Key Laboratory for Matter Microstructure and Function of Hunan Province, Key Laboratory of Low-dimensional Quantum Structures and Quantum Control, School of Physics and Electronics, Hunan Normal University, Changsha 410082, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory for Matter Microstructure and Function of Hunan Province, Key Laboratory of Low-dimensional Quantum Structures and Quantum Control, School of Physics and Electronics, Hunan Normal University, Changsha 410082, P. R. China","institution_ids":["https://openalex.org/I173759888"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031203283","display_name":"Jingdong Song","orcid":"https://orcid.org/0000-0001-8808-1981"},"institutions":[{"id":"https://openalex.org/I4210140986","display_name":"National Institute for Viral Disease Control and Prevention","ror":"https://ror.org/04b1sh213","country_code":"CN","type":"government","lineage":["https://openalex.org/I184490438","https://openalex.org/I4210127390","https://openalex.org/I4210140986","https://openalex.org/I4210151987"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jingdong Song","raw_affiliation_strings":["National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, P. R. China"],"raw_orcid":"https://orcid.org/0000-0001-8808-1981","affiliations":[{"raw_affiliation_string":"National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, P. R. China","institution_ids":["https://openalex.org/I4210140986"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5031203283"],"corresponding_institution_ids":["https://openalex.org/I4210140986"],"apc_list":null,"apc_paid":null,"fwci":0.2079,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.58294934,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":97},"biblio":{"volume":"22","issue":"02","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11775","display_name":"COVID-19 diagnosis using AI","score":0.9952999949455261,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11775","display_name":"COVID-19 diagnosis using AI","score":0.9952999949455261,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13114","display_name":"Image Processing Techniques and Applications","score":0.9904999732971191,"subfield":{"id":"https://openalex.org/subfields/2214","display_name":"Media Technology"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.983299970626831,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/jaccard-index","display_name":"Jaccard index","score":0.8275712728500366},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7063300609588623},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.6725060343742371},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6565688252449036},{"id":"https://openalex.org/keywords/deep-learning","display_name":"Deep learning","score":0.5889410972595215},{"id":"https://openalex.org/keywords/dice","display_name":"Dice","score":0.5718036890029907},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.5283292531967163},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.40219008922576904},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.12035155296325684},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.08213096857070923}],"concepts":[{"id":"https://openalex.org/C203519979","wikidata":"https://www.wikidata.org/wiki/Q865360","display_name":"Jaccard index","level":3,"score":0.8275712728500366},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7063300609588623},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.6725060343742371},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6565688252449036},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.5889410972595215},{"id":"https://openalex.org/C22029948","wikidata":"https://www.wikidata.org/wiki/Q45089","display_name":"Dice","level":2,"score":0.5718036890029907},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.5283292531967163},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.40219008922576904},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.12035155296325684},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.08213096857070923},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1142/s0219691323500479","is_oa":false,"landing_page_url":"https://doi.org/10.1142/s0219691323500479","pdf_url":null,"source":{"id":"https://openalex.org/S56986848","display_name":"International Journal of Wavelets Multiresolution and Information Processing","issn_l":"0219-6913","issn":["0219-6913","1793-690X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319815","host_organization_name":"World Scientific","host_organization_lineage":["https://openalex.org/P4310319815"],"host_organization_lineage_names":["World Scientific"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Wavelets, Multiresolution and Information Processing","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1490088282","display_name":null,"funder_award_id":"2022SKLID203","funder_id":"https://openalex.org/F4320336343","funder_display_name":"State Key Laboratory of Infectious Disease Prevention and Control"},{"id":"https://openalex.org/G2426847354","display_name":null,"funder_award_id":"621QN216","funder_id":"https://openalex.org/F4320322866","funder_display_name":"Natural Science Foundation of Hainan Province"},{"id":"https://openalex.org/G347296885","display_name":null,"funder_award_id":"Hnky2021-13","funder_id":"https://openalex.org/F4320326677","funder_display_name":"Education Department of Hainan Province"},{"id":"https://openalex.org/G8076634887","display_name":null,"funder_award_id":"2022YFC2602202","funder_id":"https://openalex.org/F4320316314","funder_display_name":"Key Technologies Research and Development Program of Anhui Province"}],"funders":[{"id":"https://openalex.org/F4320316314","display_name":"Key Technologies Research and Development Program of Anhui Province","ror":null},{"id":"https://openalex.org/F4320322866","display_name":"Natural Science Foundation of Hainan Province","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320326677","display_name":"Education Department of Hainan Province","ror":null},{"id":"https://openalex.org/F4320336343","display_name":"State Key Laboratory of Infectious Disease Prevention and Control","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W1568245674","https://openalex.org/W1602453855","https://openalex.org/W1986443131","https://openalex.org/W2057511190","https://openalex.org/W2081477511","https://openalex.org/W2086651550","https://openalex.org/W2103821863","https://openalex.org/W2104548316","https://openalex.org/W2108639727","https://openalex.org/W2141189517","https://openalex.org/W2384666987","https://openalex.org/W2790326488","https://openalex.org/W2900320412","https://openalex.org/W2903440260","https://openalex.org/W2917240371","https://openalex.org/W2946970385","https://openalex.org/W2979499381","https://openalex.org/W2991009889","https://openalex.org/W3011528525","https://openalex.org/W3037414627","https://openalex.org/W3093565638","https://openalex.org/W3102708391","https://openalex.org/W3112175976","https://openalex.org/W3171728179","https://openalex.org/W4224246723"],"related_works":["https://openalex.org/W3104750253","https://openalex.org/W4254879869","https://openalex.org/W2475857072","https://openalex.org/W4366341510","https://openalex.org/W3022576529","https://openalex.org/W3021239166","https://openalex.org/W2390936256","https://openalex.org/W3012828488","https://openalex.org/W2553941787","https://openalex.org/W4315434538"],"abstract_inverted_index":{"Due":[0],"to":[1,46,88,111,166,181],"the":[2,20,26,80,129,151,167],"advantages":[3],"of":[4,23,28,55,153,169],"direct":[5],"visualization":[6],"and":[7,84,94,108,137,144,156,178],"high":[8],"resolution,":[9],"transmission":[10],"electron":[11],"microscopy":[12],"(TEM)":[13],"technology":[14],"has":[15],"been":[16,34],"widely":[17],"used":[18],"in":[19,140,147,184],"morphological":[21],"identification":[22,41,50],"viruses.":[24],"With":[25],"development":[27,168],"artificial":[29],"intelligence":[30],"(AI),":[31],"there":[32],"have":[33],"some":[35],"studies":[36],"on":[37,75],"automated":[38,163],"TEM":[39],"virus":[40,49,71,92],"using":[42,122],"deep":[43],"learning.":[44,77,124],"However,":[45],"achieve":[47],"effective":[48],"results,":[51],"a":[52,90,176],"large":[53],"number":[54],"high-quality":[56],"labeled":[57],"images":[58],"are":[59],"required":[60],"for":[61],"network":[62,99],"training.":[63],"In":[64],"this":[65],"work,":[66],"we":[67],"propose":[68],"an":[69,96,101],"automatic":[70],"segmentation":[72,121],"method":[73,155,164],"based":[74],"few-shot":[76,123,131],"We":[78],"use":[79],"Chikungunya":[81],"virus,":[82,86],"Parapoxvirus":[83],"Marburg":[85],"etc.":[87],"construct":[89],"pre-training":[91],"dataset":[93],"train":[95],"attention":[97,106],"U-Net-like":[98],"with":[100,175],"encoder":[102],"module,":[103,105],"relationship":[104],"module":[107,110],"decoding":[109],"realize":[112],"severe":[113],"acute":[114],"respiratory":[115],"syndrome":[116],"coronavirus":[117],"type":[118],"2":[119],"(SARS-CoV-2)":[120],"The":[125],"experiment":[126],"shows":[127],"that":[128],"proposed":[130],"learning":[132],"methods":[133],"yield":[134],"0.900":[135],"Dice":[136,143],"0.828":[138],"Jaccard":[139,146],"1-shot,":[141],"0.903":[142],"0.832":[145],"5-shot,":[148],"which":[149],"demonstrates":[150],"effectiveness":[152],"our":[154],"outperforms":[157],"other":[158],"promising":[159],"methods.":[160],"Our":[161],"fully":[162],"contributes":[165],"medical":[170],"virology":[171],"by":[172],"providing":[173],"virologists":[174],"low-cost":[177],"accurate":[179],"approach":[180],"identify":[182],"SARS-CoV-2":[183],"TEM.":[185]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2025-10-10T00:00:00"}