{"id":"https://openalex.org/W4408948782","doi":"https://doi.org/10.1142/s0129065725500339","title":"Predicting Intraoperative Burst Suppression Using Preoperative EEG and Patient Characteristics","display_name":"Predicting Intraoperative Burst Suppression Using Preoperative EEG and Patient Characteristics","publication_year":2025,"publication_date":"2025-03-28","ids":{"openalex":"https://openalex.org/W4408948782","doi":"https://doi.org/10.1142/s0129065725500339","pmid":"https://pubmed.ncbi.nlm.nih.gov/40230258"},"language":"en","primary_location":{"id":"doi:10.1142/s0129065725500339","is_oa":false,"landing_page_url":"https://doi.org/10.1142/s0129065725500339","pdf_url":null,"source":{"id":"https://openalex.org/S197665576","display_name":"International Journal of Neural Systems","issn_l":"0129-0657","issn":["0129-0657","1793-6462"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319815","host_organization_name":"World Scientific","host_organization_lineage":["https://openalex.org/P4310319815"],"host_organization_lineage_names":["World Scientific"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Neural Systems","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://cris.maastrichtuniversity.nl/en/publications/3c70d4d7-154b-43f3-a65b-29c88c8a9dca","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100751322","display_name":"Jianxing He","orcid":"https://orcid.org/0000-0003-1737-8192"},"institutions":[{"id":"https://openalex.org/I34352273","display_name":"Maastricht University","ror":"https://ror.org/02jz4aj89","country_code":"NL","type":"education","lineage":["https://openalex.org/I34352273"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Jingyi He","raw_affiliation_strings":["Department of Advanced Computing Sciences, Maastricht University, 6211 LK Maastricht, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Advanced Computing Sciences, Maastricht University, 6211 LK Maastricht, The Netherlands","institution_ids":["https://openalex.org/I34352273"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028663367","display_name":"Jo\u00ebl Karel","orcid":"https://orcid.org/0000-0001-6209-3589"},"institutions":[{"id":"https://openalex.org/I34352273","display_name":"Maastricht University","ror":"https://ror.org/02jz4aj89","country_code":"NL","type":"education","lineage":["https://openalex.org/I34352273"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Jo\u00ebl M. H. Karel","raw_affiliation_strings":["Department of Advanced Computing Sciences, Maastricht University, 6211 LK Maastricht, The Netherlands"],"raw_orcid":"https://orcid.org/0000-0001-6209-3589","affiliations":[{"raw_affiliation_string":"Department of Advanced Computing Sciences, Maastricht University, 6211 LK Maastricht, The Netherlands","institution_ids":["https://openalex.org/I34352273"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088067171","display_name":"Marcus L.F. Janssen","orcid":"https://orcid.org/0000-0003-0030-7224"},"institutions":[{"id":"https://openalex.org/I34352273","display_name":"Maastricht University","ror":"https://ror.org/02jz4aj89","country_code":"NL","type":"education","lineage":["https://openalex.org/I34352273"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Marcus L. F. Janssen","raw_affiliation_strings":["Department of Clinical Neurophysiology, Maastricht University Medical Center, 6229 HX Maastricht, The Netherlands"],"raw_orcid":"https://orcid.org/0000-0003-0030-7224","affiliations":[{"raw_affiliation_string":"Department of Clinical Neurophysiology, Maastricht University Medical Center, 6229 HX Maastricht, The Netherlands","institution_ids":["https://openalex.org/I34352273"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068782707","display_name":"Erik D. Gommer","orcid":"https://orcid.org/0000-0003-1054-2682"},"institutions":[{"id":"https://openalex.org/I34352273","display_name":"Maastricht University","ror":"https://ror.org/02jz4aj89","country_code":"NL","type":"education","lineage":["https://openalex.org/I34352273"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Erik D. Gommer","raw_affiliation_strings":["Department of Clinical Neurophysiology, Maastricht University Medical Center, 6229 HX Maastricht, The Netherlands"],"raw_orcid":"https://orcid.org/0000-0003-1054-2682","affiliations":[{"raw_affiliation_string":"Department of Clinical Neurophysiology, Maastricht University Medical Center, 6229 HX Maastricht, The Netherlands","institution_ids":["https://openalex.org/I34352273"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083307813","display_name":"Catherine J. Vossen","orcid":"https://orcid.org/0000-0003-3523-1696"},"institutions":[{"id":"https://openalex.org/I2800191616","display_name":"Maastricht University Medical Centre","ror":"https://ror.org/02d9ce178","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800191616"]},{"id":"https://openalex.org/I34352273","display_name":"Maastricht University","ror":"https://ror.org/02jz4aj89","country_code":"NL","type":"education","lineage":["https://openalex.org/I34352273"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Catherine J. Vossen","raw_affiliation_strings":["Department of Anesthesiology and Pain Medicine, Maastricht University Medical Center, 6229 HX Maastricht, The Netherlands"],"raw_orcid":"https://orcid.org/0000-0003-3523-1696","affiliations":[{"raw_affiliation_string":"Department of Anesthesiology and Pain Medicine, Maastricht University Medical Center, 6229 HX Maastricht, The Netherlands","institution_ids":["https://openalex.org/I2800191616","https://openalex.org/I34352273"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071538209","display_name":"Enrique Hortal","orcid":"https://orcid.org/0000-0003-2119-4169"},"institutions":[{"id":"https://openalex.org/I34352273","display_name":"Maastricht University","ror":"https://ror.org/02jz4aj89","country_code":"NL","type":"education","lineage":["https://openalex.org/I34352273"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Enrique Hortal","raw_affiliation_strings":["Department of Advanced Computing Sciences, Maastricht University, 6211 LK Maastricht, The Netherlands"],"raw_orcid":"https://orcid.org/0000-0003-2119-4169","affiliations":[{"raw_affiliation_string":"Department of Advanced Computing Sciences, Maastricht University, 6211 LK Maastricht, The Netherlands","institution_ids":["https://openalex.org/I34352273"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.0311,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.75106709,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":98},"biblio":{"volume":"35","issue":"06","first_page":"2550033","last_page":"2550033"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11930","display_name":"Cardiac, Anesthesia and Surgical Outcomes","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11930","display_name":"Cardiac, Anesthesia and Surgical Outcomes","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10436","display_name":"Anesthesia and Sedative Agents","score":0.9114999771118164,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/electroencephalography","display_name":"Electroencephalography","score":0.7126637697219849},{"id":"https://openalex.org/keywords/burst-suppression","display_name":"Burst suppression","score":0.6678892970085144},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.4705379903316498},{"id":"https://openalex.org/keywords/anesthesia","display_name":"Anesthesia","score":0.3778051733970642},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.35770994424819946},{"id":"https://openalex.org/keywords/psychiatry","display_name":"Psychiatry","score":0.06280097365379333}],"concepts":[{"id":"https://openalex.org/C522805319","wikidata":"https://www.wikidata.org/wiki/Q179965","display_name":"Electroencephalography","level":2,"score":0.7126637697219849},{"id":"https://openalex.org/C167639399","wikidata":"https://www.wikidata.org/wiki/Q17006613","display_name":"Burst suppression","level":3,"score":0.6678892970085144},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4705379903316498},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.3778051733970642},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.35770994424819946},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.06280097365379333}],"mesh":[{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000768","descriptor_name":"Anesthesia, General","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000768","descriptor_name":"Anesthesia, General","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016894","descriptor_name":"Endarterectomy, Carotid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016894","descriptor_name":"Endarterectomy, Carotid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064795","descriptor_name":"Intraoperative Neurophysiological Monitoring","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D064795","descriptor_name":"Intraoperative Neurophysiological Monitoring","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1142/s0129065725500339","is_oa":false,"landing_page_url":"https://doi.org/10.1142/s0129065725500339","pdf_url":null,"source":{"id":"https://openalex.org/S197665576","display_name":"International Journal of Neural Systems","issn_l":"0129-0657","issn":["0129-0657","1793-6462"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319815","host_organization_name":"World Scientific","host_organization_lineage":["https://openalex.org/P4310319815"],"host_organization_lineage_names":["World Scientific"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Neural Systems","raw_type":"journal-article"},{"id":"pmid:40230258","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40230258","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of neural systems","raw_type":null},{"id":"pmh:oai:cris.maastrichtuniversity.nl:openaire/3c70d4d7-154b-43f3-a65b-29c88c8a9dca","is_oa":true,"landing_page_url":"https://cris.maastrichtuniversity.nl/en/publications/3c70d4d7-154b-43f3-a65b-29c88c8a9dca","pdf_url":null,"source":{"id":"https://openalex.org/S4306402616","display_name":"Research Publications (Maastricht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I34352273","host_organization_name":"Maastricht University","host_organization_lineage":["https://openalex.org/I34352273"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"He, J, Karel, J M H, Janssen, M L F, Gommer, E D, Vossen, C J & Hortal, E 2025, 'Predicting Intraoperative Burst Suppression Using Preoperative EEG and Patient Characteristics', International Journal of Neural Systems, vol. 35, no. 6, 2550033. https://doi.org/10.1142/S0129065725500339","raw_type":"info:eu-repo/semantics/publishedVersion"}],"best_oa_location":{"id":"pmh:oai:cris.maastrichtuniversity.nl:openaire/3c70d4d7-154b-43f3-a65b-29c88c8a9dca","is_oa":true,"landing_page_url":"https://cris.maastrichtuniversity.nl/en/publications/3c70d4d7-154b-43f3-a65b-29c88c8a9dca","pdf_url":null,"source":{"id":"https://openalex.org/S4306402616","display_name":"Research Publications (Maastricht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I34352273","host_organization_name":"Maastricht University","host_organization_lineage":["https://openalex.org/I34352273"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"He, J, Karel, J M H, Janssen, M L F, Gommer, E D, Vossen, C J & Hortal, E 2025, 'Predicting Intraoperative Burst Suppression Using Preoperative EEG and Patient Characteristics', International Journal of Neural Systems, vol. 35, no. 6, 2550033. https://doi.org/10.1142/S0129065725500339","raw_type":"info:eu-repo/semantics/publishedVersion"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W1542104641","https://openalex.org/W2022894064","https://openalex.org/W2040327687","https://openalex.org/W2084444573","https://openalex.org/W2128495200","https://openalex.org/W2137234026","https://openalex.org/W2148143831","https://openalex.org/W2148230032","https://openalex.org/W2266905942","https://openalex.org/W2782858624","https://openalex.org/W2942270306","https://openalex.org/W3110361010","https://openalex.org/W3121468319","https://openalex.org/W3127469572","https://openalex.org/W4206439137","https://openalex.org/W4385064284","https://openalex.org/W4386417923","https://openalex.org/W4396867326","https://openalex.org/W4399160148","https://openalex.org/W4401855069","https://openalex.org/W4402836844","https://openalex.org/W4404639001"],"related_works":["https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W2018792212","https://openalex.org/W1481458145","https://openalex.org/W2137121869","https://openalex.org/W2800991009","https://openalex.org/W4368341778","https://openalex.org/W2802490282","https://openalex.org/W1987571512","https://openalex.org/W2057366091"],"abstract_inverted_index":{"Burst":[0],"suppression":[1],"(BS)":[2],"is":[3,18],"an":[4,151,160,184,237,268],"electroencephalogram":[5],"(EEG)":[6],"pattern":[7],"observed":[8],"in":[9],"patients":[10,81,133,165,196],"undergoing":[11],"general":[12],"anesthesia.":[13],"The":[14,34,220],"occurrence":[15,125],"of":[16,38,45,105,113,144,153,163,186,195,239,243,249],"BS":[17,39,62,68,124,157],"associated":[19],"with":[20,171,183,227],"adverse":[21],"outcomes":[22],"such":[23],"as":[24,271],"postoperative":[25,32],"delirium,":[26],"extended":[27],"recovery":[28],"time,":[29],"and":[30,36,51,67,74,213,230,241,262],"increased":[31],"mortality.":[33],"detection":[35,63,148],"prediction":[37,69,158],"can":[40],"help":[41],"expedite":[42],"the":[43,58,102,110,131,140,146,156,172,180,193,203,210,215,276],"evaluation":[44],"patient":[46,53,75],"conditions,":[47],"optimize":[48],"anesthesia":[49],"administration,":[50],"improve":[52],"safety.":[54],"This":[55],"study":[56],"explores":[57],"potential":[59],"for":[60,109],"automatic":[61,111,147],"using":[64,70,126,198],"intraoperative":[65],"EEG":[66,72,95,137],"preoperative":[71,127],"signals":[73],"characteristics.":[76],"A":[77],"dataset":[78],"comprising":[79],"287":[80],"who":[82],"underwent":[83],"carotid":[84],"endarterectomy":[85],"procedures":[86],"at":[87,101],"Maastricht":[88],"University":[89],"Medical":[90],"Center+":[91],"was":[92,107,166,218],"analyzed.":[93],"An":[94],"toolbox":[96],"developed":[97],"by":[98,136,267],"T.":[99],"Zhan":[100],"Massachusetts":[103],"Institute":[104],"Technology":[106],"utilized":[108],"detection/annotation":[112],"BS,":[114],"while":[115],"five":[116],"machine":[117],"learning":[118],"classifiers":[119],"were":[120,265],"employed":[121],"to":[122,201,208,278],"predict":[123],"data.":[128],"Based":[129],"on":[130],"160":[132],"manually":[134],"annotated":[135],"experts":[138],"(regarding":[139],"presence":[141],"or":[142],"absence":[143],"BS),":[145],"tool":[149],"demonstrated":[150,223],"accuracy":[152,185,238],"0.75.":[154],"For":[155],"task,":[159],"initial":[161],"subset":[162],"120":[164],"evaluated,":[167],"showing":[168],"modest":[169],"performance,":[170],"K-nearest":[173],"neighbors":[174],"([Formula:":[175],"see":[176],"text])":[177],"classifier":[178],"achieving":[179,236],"best":[181],"results,":[182],"0.72.":[187],"Subsequent":[188],"experiments":[189],"indicated":[190],"that":[191],"increasing":[192],"number":[194],"(by":[197],"Zhan\u2019s":[199],"Toolbox":[200],"annotate":[202],"unlabeled":[204],"instances),":[205],"applying":[206],"SMOTE":[207],"balance":[209],"training":[211],"set,":[212],"enriching":[214],"feature":[216],"set":[217],"beneficial.":[219],"final":[221],"experiment":[222],"a":[224],"significant":[225],"improvement,":[226],"Random":[228],"Forest":[229],"Gradient":[231],"Boosting":[232],"outperforming":[233],"other":[234],"classifiers,":[235],"0.86":[240],"ROC\u2013AUC":[242],"0.94.":[244],"Patient":[245],"characteristics,":[246],"including":[247],"type":[248],"anesthetic":[250],"agents,":[251],"symptoms,":[252],"age,":[253],"mean":[254,258],"absolute":[255,259],"delta":[256],"power,":[257,261],"theta":[260],"cognitive":[263],"impairment,":[264],"identified":[266],"xAI":[269],"method":[270],"important":[272],"features":[273],"potentially":[274],"indicating":[275],"predisposition":[277],"experience":[279],"BS.":[280]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}