{"id":"https://openalex.org/W4414183508","doi":"https://doi.org/10.1137/24m1671566","title":"Exact Switching Time Distributions for Autoregulated Gene Expression Models with mRNA and Protein Descriptions","display_name":"Exact Switching Time Distributions for Autoregulated Gene Expression Models with mRNA and Protein Descriptions","publication_year":2025,"publication_date":"2025-09-15","ids":{"openalex":"https://openalex.org/W4414183508","doi":"https://doi.org/10.1137/24m1671566"},"language":"en","primary_location":{"id":"doi:10.1137/24m1671566","is_oa":false,"landing_page_url":"https://doi.org/10.1137/24m1671566","pdf_url":null,"source":{"id":"https://openalex.org/S77200987","display_name":"SIAM Journal on Applied Mathematics","issn_l":"0036-1399","issn":["0036-1399","1095-712X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320508","host_organization_name":"Society for Industrial and Applied Mathematics","host_organization_lineage":["https://openalex.org/P4310320508"],"host_organization_lineage_names":["Society for Industrial and Applied Mathematics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SIAM Journal on Applied Mathematics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034772874","display_name":"Shan Liu","orcid":"https://orcid.org/0000-0001-5511-2139"},"institutions":[{"id":"https://openalex.org/I4210139958","display_name":"Beijing Computational Science Research Center","ror":"https://ror.org/04tavf782","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210139958"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Shan Liu","raw_affiliation_strings":["Applied and Computational Mathematics Division, Beijing Computational Science Research Center, Beijing, 100193 China","These authors contributed equally to this work"],"affiliations":[{"raw_affiliation_string":"Applied and Computational Mathematics Division, Beijing Computational Science Research Center, Beijing, 100193 China","institution_ids":["https://openalex.org/I4210139958"]},{"raw_affiliation_string":"These authors contributed equally to this work","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020951351","display_name":"Bingjie Wu","orcid":"https://orcid.org/0000-0002-8180-3002"},"institutions":[{"id":"https://openalex.org/I4210139958","display_name":"Beijing Computational Science Research Center","ror":"https://ror.org/04tavf782","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210139958"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bingjie Wu","raw_affiliation_strings":["Applied and Computational Mathematics Division, Beijing Computational Science Research Center, Beijing, 100193 China","These authors contributed equally to this work"],"affiliations":[{"raw_affiliation_string":"Applied and Computational Mathematics Division, Beijing Computational Science Research Center, Beijing, 100193 China","institution_ids":["https://openalex.org/I4210139958"]},{"raw_affiliation_string":"These authors contributed equally to this work","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100416019","display_name":"Chen Jia","orcid":"https://orcid.org/0000-0002-3375-4373"},"institutions":[{"id":"https://openalex.org/I4210139958","display_name":"Beijing Computational Science Research Center","ror":"https://ror.org/04tavf782","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210139958"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chen Jia","raw_affiliation_strings":["Corresponding author. Applied and Computational Mathematics Division, Beijing Computational Science Research Center, Beijing, 100193 China"],"affiliations":[{"raw_affiliation_string":"Corresponding author. Applied and Computational Mathematics Division, Beijing Computational Science Research Center, Beijing, 100193 China","institution_ids":["https://openalex.org/I4210139958"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5034772874"],"corresponding_institution_ids":["https://openalex.org/I4210139958"],"apc_list":null,"apc_paid":null,"fwci":0.913,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.7877039,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"85","issue":"5","first_page":"1998","last_page":"2025"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.995199978351593,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/messenger-rna","display_name":"Messenger RNA","score":0.7161999940872192},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.6251999735832214},{"id":"https://openalex.org/keywords/expression","display_name":"Expression (computer science)","score":0.5230000019073486},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.5034000277519226},{"id":"https://openalex.org/keywords/regulation-of-gene-expression","display_name":"Regulation of gene expression","score":0.35499998927116394},{"id":"https://openalex.org/keywords/protein-expression","display_name":"Protein expression","score":0.3402999937534332}],"concepts":[{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.7161999940872192},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.6251999735832214},{"id":"https://openalex.org/C90559484","wikidata":"https://www.wikidata.org/wiki/Q778379","display_name":"Expression (computer science)","level":2,"score":0.5230000019073486},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5206000208854675},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5034000277519226},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.49619999527931213},{"id":"https://openalex.org/C165864922","wikidata":"https://www.wikidata.org/wiki/Q411391","display_name":"Regulation of gene expression","level":3,"score":0.35499998927116394},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.35010001063346863},{"id":"https://openalex.org/C6856738","wikidata":"https://www.wikidata.org/wiki/Q331672","display_name":"Protein expression","level":3,"score":0.3402999937534332},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3400999903678894},{"id":"https://openalex.org/C2992708514","wikidata":"https://www.wikidata.org/wiki/Q48968323","display_name":"Quantitative biology","level":2,"score":0.3310000002384186},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2994000017642975},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.28130000829696655},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.2793999910354614},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.2671999931335449},{"id":"https://openalex.org/C18431079","wikidata":"https://www.wikidata.org/wiki/Q1502169","display_name":"Gene expression profiling","level":4,"score":0.26249998807907104},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.2578999996185303},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.25220000743865967}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1137/24m1671566","is_oa":false,"landing_page_url":"https://doi.org/10.1137/24m1671566","pdf_url":null,"source":{"id":"https://openalex.org/S77200987","display_name":"SIAM Journal on Applied Mathematics","issn_l":"0036-1399","issn":["0036-1399","1095-712X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320508","host_organization_name":"Society for Industrial and Applied Mathematics","host_organization_lineage":["https://openalex.org/P4310320508"],"host_organization_lineage_names":["Society for Industrial and Applied Mathematics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SIAM Journal on Applied Mathematics","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":56,"referenced_works":["https://openalex.org/W1590222219","https://openalex.org/W1862404147","https://openalex.org/W1978750558","https://openalex.org/W1980944685","https://openalex.org/W1998469587","https://openalex.org/W1998878730","https://openalex.org/W2013244831","https://openalex.org/W2016546231","https://openalex.org/W2017886758","https://openalex.org/W2020176076","https://openalex.org/W2031718086","https://openalex.org/W2039486340","https://openalex.org/W2060457543","https://openalex.org/W2062029454","https://openalex.org/W2066594542","https://openalex.org/W2067630518","https://openalex.org/W2091568014","https://openalex.org/W2096705138","https://openalex.org/W2105512180","https://openalex.org/W2109117831","https://openalex.org/W2110699703","https://openalex.org/W2122121413","https://openalex.org/W2128551987","https://openalex.org/W2134440848","https://openalex.org/W2140347764","https://openalex.org/W2167244112","https://openalex.org/W2169643501","https://openalex.org/W2340877239","https://openalex.org/W2550226555","https://openalex.org/W2729713741","https://openalex.org/W2766928367","https://openalex.org/W2774001441","https://openalex.org/W2790359481","https://openalex.org/W2811137963","https://openalex.org/W2887216660","https://openalex.org/W2932160358","https://openalex.org/W2963919107","https://openalex.org/W2986406094","https://openalex.org/W2999914121","https://openalex.org/W3007264533","https://openalex.org/W3008225830","https://openalex.org/W3021249883","https://openalex.org/W3081370983","https://openalex.org/W3102066192","https://openalex.org/W3153152792","https://openalex.org/W3164077165","https://openalex.org/W4245668478","https://openalex.org/W4311173915","https://openalex.org/W4366742655","https://openalex.org/W4367834088","https://openalex.org/W4391264762","https://openalex.org/W4391876285","https://openalex.org/W4394616539","https://openalex.org/W4396886318","https://openalex.org/W4399502777","https://openalex.org/W4401245445"],"related_works":[],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-03-07T16:01:11.037858","created_date":"2025-10-10T00:00:00"}
