{"id":"https://openalex.org/W3162772504","doi":"https://doi.org/10.1137/20m1370720","title":"Morphomechanical model of the Torsional c-looping in the embryonic heart","display_name":"Morphomechanical model of the Torsional c-looping in the embryonic heart","publication_year":2021,"publication_date":"2021-01-01","ids":{"openalex":"https://openalex.org/W3162772504","doi":"https://doi.org/10.1137/20m1370720","mag":"3162772504"},"language":"en","primary_location":{"id":"pmh:oai:iris.unive.it:10278/5115529","is_oa":false,"landing_page_url":"https://hdl.handle.net/10278/5115529","pdf_url":null,"source":{"id":"https://openalex.org/S4306402336","display_name":"ARCA (Universit\u00e0 Ca' Foscari Venezia)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I149461666","host_organization_name":"Ca' Foscari University of Venice","host_organization_lineage":["https://openalex.org/I149461666"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},"type":"article","indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/11311/1195933","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5011467306","display_name":"Giulia Bevilacqua","orcid":"https://orcid.org/0000-0002-4502-0924"},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Bevilacqua G.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008852163","display_name":"Pasquale Ciarletta","orcid":"https://orcid.org/0000-0002-1011-5587"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ciarletta P.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5013754088","display_name":"Alfio Quarteroni","orcid":"https://orcid.org/0000-0002-5947-6885"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Quarteroni A.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5011467306"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.4706,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.65413534,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":96},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11677","display_name":"Congenital heart defects research","score":0.9948999881744385,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.987500011920929,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nonlinear-system","display_name":"Nonlinear system","score":0.5293251872062683},{"id":"https://openalex.org/keywords/elasticity","display_name":"Elasticity (physics)","score":0.44356417655944824},{"id":"https://openalex.org/keywords/mechanical-engineering","display_name":"Mechanical engineering","score":0.34297695755958557},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3393968641757965},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.32239285111427307},{"id":"https://openalex.org/keywords/thermodynamics","display_name":"Thermodynamics","score":0.2955661714076996},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.2828768491744995},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.2570974826812744}],"concepts":[{"id":"https://openalex.org/C158622935","wikidata":"https://www.wikidata.org/wiki/Q660848","display_name":"Nonlinear system","level":2,"score":0.5293251872062683},{"id":"https://openalex.org/C121854251","wikidata":"https://www.wikidata.org/wiki/Q62932","display_name":"Elasticity (physics)","level":2,"score":0.44356417655944824},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.34297695755958557},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3393968641757965},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.32239285111427307},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.2955661714076996},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.2828768491744995},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.2570974826812744},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:iris.unive.it:10278/5115529","is_oa":false,"landing_page_url":"https://hdl.handle.net/10278/5115529","pdf_url":null,"source":{"id":"https://openalex.org/S4306402336","display_name":"ARCA (Universit\u00e0 Ca' Foscari Venezia)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I149461666","host_organization_name":"Ca' Foscari University of Venice","host_organization_lineage":["https://openalex.org/I149461666"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:re.public.polimi.it:11311/1195933","is_oa":true,"landing_page_url":"http://hdl.handle.net/11311/1195933","pdf_url":null,"source":{"id":"https://openalex.org/S4306400312","display_name":"Virtual Community of Pathological Anatomy (University of Castilla La Mancha)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I79189158","host_organization_name":"University of Castilla-La Mancha","host_organization_lineage":["https://openalex.org/I79189158"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:re.public.polimi.it:11311/1195933","is_oa":true,"landing_page_url":"http://hdl.handle.net/11311/1195933","pdf_url":null,"source":{"id":"https://openalex.org/S4306400312","display_name":"Virtual Community of Pathological Anatomy (University of Castilla La Mancha)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I79189158","host_organization_name":"University of Castilla-La Mancha","host_organization_lineage":["https://openalex.org/I79189158"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/2","score":0.4300000071525574,"display_name":"Zero hunger"}],"awards":[{"id":"https://openalex.org/G4130757338","display_name":null,"funder_award_id":"740132","funder_id":"https://openalex.org/F4320332999","funder_display_name":"Horizon 2020 Framework Programme"}],"funders":[{"id":"https://openalex.org/F4320321873","display_name":"Ministero dell\u2019Istruzione, dell\u2019Universit\u00e0 e della Ricerca","ror":"https://ror.org/0166hxq48"},{"id":"https://openalex.org/F4320332999","display_name":"Horizon 2020 Framework Programme","ror":"https://ror.org/00k4n6c32"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":39,"referenced_works":["https://openalex.org/W185434929","https://openalex.org/W1497745230","https://openalex.org/W1617464831","https://openalex.org/W1972235643","https://openalex.org/W1974972774","https://openalex.org/W1981435515","https://openalex.org/W1991494676","https://openalex.org/W2005692673","https://openalex.org/W2030461353","https://openalex.org/W2047398492","https://openalex.org/W2051998962","https://openalex.org/W2052221473","https://openalex.org/W2069865606","https://openalex.org/W2070571481","https://openalex.org/W2072249525","https://openalex.org/W2074741263","https://openalex.org/W2078419759","https://openalex.org/W2084962429","https://openalex.org/W2085663543","https://openalex.org/W2086353489","https://openalex.org/W2086550248","https://openalex.org/W2091566299","https://openalex.org/W2133946902","https://openalex.org/W2134670334","https://openalex.org/W2135789936","https://openalex.org/W2140034535","https://openalex.org/W2144297580","https://openalex.org/W2150822705","https://openalex.org/W2152544500","https://openalex.org/W2158082645","https://openalex.org/W2158503864","https://openalex.org/W2169975206","https://openalex.org/W2240255094","https://openalex.org/W2331963013","https://openalex.org/W2767959857","https://openalex.org/W2921115001","https://openalex.org/W2921269803","https://openalex.org/W2988140554","https://openalex.org/W3001742035"],"related_works":["https://openalex.org/W2748952813","https://openalex.org/W4246450666","https://openalex.org/W4388998267","https://openalex.org/W2898370298","https://openalex.org/W4390401159","https://openalex.org/W2744391499","https://openalex.org/W3120461830","https://openalex.org/W4230250635","https://openalex.org/W3041790586","https://openalex.org/W2018879842"],"abstract_inverted_index":{"Before":[0],"septation":[1],"processes":[2],"shape":[3,159],"its":[4],"four":[5],"chambers,":[6],"the":[7,20,25,41,53,56,87,95,99,110,119,127,130,134,144,151,161],"embryonic":[8],"heart":[9,26,57,100],"is":[10,28],"a":[11,31,49,62,76,105,124,155],"straight":[12],"tube":[13,27,58,131,153],"that":[14,59,68,150],"spontaneously":[15],"bends":[16],"and":[17,37,132],"twists":[18],"breaking":[19],"left-right":[21],"symmetry.":[22],"In":[23,44],"particular,":[24],"subjected":[29],"to":[30,80,117,142],"cell":[32],"remodeling":[33,136],"inducing":[34],"ventral":[35],"bending":[36],"dextral":[38],"torsion":[39,54],"during":[40],"c-looping":[42,122],"phase.":[43],"this":[45,69],"work":[46],"we":[47,103],"propose":[48],"morphomechanical":[50],"model":[51],"for":[52],"of":[55,82,90,109,121,126,129,133,164],"behaves":[60],"as":[61,75,123],"nonlinear":[63,112,146],"elastic":[64,113],"body.":[65],"We":[66,138],"hypothesize":[67],"spontaneous":[70],"looping":[71],"can":[72],"be":[73],"modeled":[74],"mechanical":[77],"instability":[78],"due":[79],"accumulation":[81],"residual":[83],"stresses":[84],"induced":[85],"by":[86],"geometrical":[88,165],"frustration":[89],"tissue":[91],"remodeling,":[92],"which":[93],"mimics":[94],"cellular":[96],"rearrangement":[97],"within":[98],"tube.":[101],"Thus,":[102],"perform":[104,139],"linear":[106],"stability":[107],"analysis":[108],"resulting":[111],"boundary":[114],"value":[115],"problem":[116],"determine":[118],"onset":[120],"function":[125],"geometry":[128],"internal":[135],"rate.":[137],"numerical":[140],"simulations":[141],"study":[143],"fully":[145],"morphological":[147],"transition,":[148],"showing":[149],"soft":[152],"develops":[154],"realistic":[156],"self-contacting":[157],"looped":[158],"in":[160],"physiological":[162],"range":[163],"parameters.":[166]},"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1}],"updated_date":"2026-04-28T14:05:53.105641","created_date":"2025-10-10T00:00:00"}
