{"id":"https://openalex.org/W2096340782","doi":"https://doi.org/10.1136/amiajnl-2014-002965","title":"Seeing the forest through the trees: uncovering phenomic complexity through interactive network visualization","display_name":"Seeing the forest through the trees: uncovering phenomic complexity through interactive network visualization","publication_year":2014,"publication_date":"2014-10-21","ids":{"openalex":"https://openalex.org/W2096340782","doi":"https://doi.org/10.1136/amiajnl-2014-002965","mag":"2096340782","pmid":"https://pubmed.ncbi.nlm.nih.gov/25336590"},"language":"en","primary_location":{"id":"doi:10.1136/amiajnl-2014-002965","is_oa":true,"landing_page_url":"https://doi.org/10.1136/amiajnl-2014-002965","pdf_url":"https://academic.oup.com/jamia/article-pdf/22/2/324/34145512/amiajnl-2014-002965.pdf","source":{"id":"https://openalex.org/S129839026","display_name":"Journal of the American Medical Informatics Association","issn_l":"1067-5027","issn":["1067-5027","1527-974X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Medical Informatics Association","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/jamia/article-pdf/22/2/324/34145512/amiajnl-2014-002965.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5044194506","display_name":"Jeremy L. Warner","orcid":"https://orcid.org/0000-0002-2851-7242"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jeremy L Warner","raw_affiliation_strings":["Department of Biomedical Informatics, Vanderbilt University, Nashville, Tennessee, USA","Division of Hematology/Oncology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Informatics, Vanderbilt University, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"Division of Hematology/Oncology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070908224","display_name":"Joshua C. Denny","orcid":"https://orcid.org/0000-0002-3049-7332"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joshua C Denny","raw_affiliation_strings":["Department of Biomedical Informatics, Vanderbilt University, Nashville, Tennessee, USA","Division of General Internal Medicine, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Informatics, Vanderbilt University, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"Division of General Internal Medicine, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057500499","display_name":"David Kreda","orcid":"https://orcid.org/0000-0001-7132-8220"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210155419","display_name":"Center for Systems Biology","ror":"https://ror.org/05r3dyn47","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210155419","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David A Kreda","raw_affiliation_strings":["Center for Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I4210155419","https://openalex.org/I136199984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5076921758","display_name":"Gil Alterovitz","orcid":"https://orcid.org/0000-0002-0495-7059"},"institutions":[{"id":"https://openalex.org/I1288882113","display_name":"Boston Children's Hospital","ror":"https://ror.org/00dvg7y05","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210155419","display_name":"Center for Systems Biology","ror":"https://ror.org/05r3dyn47","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210155419","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gil Alterovitz","raw_affiliation_strings":["Center for Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA","Children's Hospital Informatics Program at Harvard-MIT Division of Health Science, Boston, Massachusetts, USA","Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I4210155419","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Children's Hospital Informatics Program at Harvard-MIT Division of Health Science, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I1288882113"]},{"raw_affiliation_string":"Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA","institution_ids":["https://openalex.org/I63966007"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5044194506"],"corresponding_institution_ids":["https://openalex.org/I200719446"],"apc_list":{"value":3967,"currency":"USD","value_usd":3967},"apc_paid":null,"fwci":3.9114,"has_fulltext":false,"cited_by_count":27,"citation_normalized_percentile":{"value":0.92959815,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"22","issue":"2","first_page":"324","last_page":"329"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13283","display_name":"Mental Health Research Topics","score":0.9987000226974487,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T13283","display_name":"Mental Health Research Topics","score":0.9987000226974487,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10799","display_name":"Data Visualization and Analytics","score":0.996999979019165,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9362000226974487,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/visualization","display_name":"Visualization","score":0.6816689968109131},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5686329007148743},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.5060984492301941},{"id":"https://openalex.org/keywords/interactive-visualization","display_name":"Interactive visualization","score":0.43622562289237976},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.23600172996520996}],"concepts":[{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.6816689968109131},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5686329007148743},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.5060984492301941},{"id":"https://openalex.org/C64073096","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Interactive visualization","level":3,"score":0.43622562289237976},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.23600172996520996}],"mesh":[{"descriptor_ui":"D001296","descriptor_name":"Audiovisual Aids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001296","descriptor_name":"Audiovisual Aids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001296","descriptor_name":"Audiovisual Aids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003626","descriptor_name":"Data Display","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003626","descriptor_name":"Data Display","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003626","descriptor_name":"Data Display","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1136/amiajnl-2014-002965","is_oa":true,"landing_page_url":"https://doi.org/10.1136/amiajnl-2014-002965","pdf_url":"https://academic.oup.com/jamia/article-pdf/22/2/324/34145512/amiajnl-2014-002965.pdf","source":{"id":"https://openalex.org/S129839026","display_name":"Journal of the American Medical Informatics Association","issn_l":"1067-5027","issn":["1067-5027","1527-974X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Medical Informatics Association","raw_type":"journal-article"},{"id":"pmid:25336590","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25336590","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Medical Informatics Association : JAMIA","raw_type":null},{"id":"pmh:oai:europepmc.org:5034218","is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6080728","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1136/amiajnl-2014-002965","is_oa":true,"landing_page_url":"https://doi.org/10.1136/amiajnl-2014-002965","pdf_url":"https://academic.oup.com/jamia/article-pdf/22/2/324/34145512/amiajnl-2014-002965.pdf","source":{"id":"https://openalex.org/S129839026","display_name":"Journal of the American Medical Informatics Association","issn_l":"1067-5027","issn":["1067-5027","1527-974X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Medical Informatics Association","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.800000011920929,"display_name":"Good health and well-being"}],"awards":[{"id":"https://openalex.org/G5151510285","display_name":null,"funder_award_id":"1R01HG004836-01","funder_id":"https://openalex.org/F4320337348","funder_display_name":"National Human Genome Research Institute"},{"id":"https://openalex.org/G6637882476","display_name":null,"funder_award_id":"4R00LM009826-03","funder_id":"https://openalex.org/F4320337372","funder_display_name":"U.S. National Library of Medicine"},{"id":"https://openalex.org/G6841222913","display_name":null,"funder_award_id":"R01LM010685","funder_id":"https://openalex.org/F4320337372","funder_display_name":"U.S. National Library of Medicine"}],"funders":[{"id":"https://openalex.org/F4320337348","display_name":"National Human Genome Research Institute","ror":"https://ror.org/00baak391"},{"id":"https://openalex.org/F4320337372","display_name":"U.S. National Library of Medicine","ror":"https://ror.org/0060t0j89"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W2096340782.pdf"},"referenced_works_count":41,"referenced_works":["https://openalex.org/W172027785","https://openalex.org/W187840612","https://openalex.org/W229097380","https://openalex.org/W1602388384","https://openalex.org/W1969208427","https://openalex.org/W1971756292","https://openalex.org/W2001556641","https://openalex.org/W2001657480","https://openalex.org/W2012486622","https://openalex.org/W2046788142","https://openalex.org/W2057913811","https://openalex.org/W2102215872","https://openalex.org/W2104608657","https://openalex.org/W2107097633","https://openalex.org/W2113105800","https://openalex.org/W2120411377","https://openalex.org/W2121382432","https://openalex.org/W2125987009","https://openalex.org/W2128965269","https://openalex.org/W2135310563","https://openalex.org/W2138399673","https://openalex.org/W2138842039","https://openalex.org/W2144360394","https://openalex.org/W2147013342","https://openalex.org/W2149386833","https://openalex.org/W2150999996","https://openalex.org/W2157150618","https://openalex.org/W2158169170","https://openalex.org/W2167482691","https://openalex.org/W2401222336","https://openalex.org/W2443233740","https://openalex.org/W2582743722","https://openalex.org/W4235457527","https://openalex.org/W4242777928","https://openalex.org/W6606934348","https://openalex.org/W6607614094","https://openalex.org/W6608852248","https://openalex.org/W6678642432","https://openalex.org/W6683614057","https://openalex.org/W6712773937","https://openalex.org/W6718536342"],"related_works":["https://openalex.org/W2006240110","https://openalex.org/W2909972699","https://openalex.org/W2751110224","https://openalex.org/W2039602384","https://openalex.org/W2496664377","https://openalex.org/W4312613920","https://openalex.org/W2288407995","https://openalex.org/W2147036980","https://openalex.org/W304756206","https://openalex.org/W2140525502"],"abstract_inverted_index":{"Our":[0],"aim":[1],"was":[2,23,52,68],"to":[3,46,140],"uncover":[4],"unrecognized":[5],"phenomic":[6],"relationships":[7,43,98],"using":[8],"force-based":[9],"network":[10,84],"visualization":[11,57,85,110],"methods,":[12],"based":[13],"on":[14,132],"observed":[15],"electronic":[16],"medical":[17],"record":[18],"data.":[19],"A":[20],"primary":[21,42],"phenotype":[22,56,90],"defined":[24],"from":[25],"actual":[26],"patient":[27,149],"profiles":[28],"in":[29,34,119],"the":[30,60,106],"Multiparameter":[31],"Intelligent":[32],"Monitoring":[33],"Intensive":[35],"Care":[36],"II":[37],"database.":[38],"Network":[39,109],"visualizations":[40],"depicting":[41],"were":[44,75],"compared":[45],"those":[47],"incorporating":[48],"secondary":[49,97],"adjacencies.":[50],"Interactivity":[51],"enabled":[53],"through":[54],"a":[55,71,87],"software":[58],"concept:":[59],"Phenomics":[61],"Advisor.":[62],"Subendocardial":[63],"infarction":[64],"with":[65,80,105],"cardiac":[66],"arrest":[67],"demonstrated":[69],"as":[70,129],"sample":[72],"phenotype;":[73],"there":[74],"332":[76],"primarily":[77],"adjacent":[78],"diagnoses,":[79],"5423":[81],"relationships.":[82],"Primary":[83],"suggested":[86],"treatment-related":[88],"complication":[89],"and":[91,138,144],"several":[92],"rare":[93],"diagnoses;":[94],"re-clustering":[95],"by":[96],"revealed":[99],"an":[100],"emergent":[101],"cluster":[102],"of":[103,124,148],"smokers":[104],"metabolic":[107],"syndrome.":[108],"reveals":[111],"phenotypic":[112],"patterns":[113],"that":[114],"may":[115,135],"have":[116],"remained":[117],"occult":[118],"pairwise":[120],"correlation":[121],"analysis.":[122],"Visualization":[123],"complex":[125],"data,":[126],"potentially":[127],"offered":[128],"point-of-care":[130],"tools":[131],"mobile":[133],"devices,":[134],"allow":[136],"clinicians":[137],"researchers":[139],"quickly":[141],"generate":[142],"hypotheses":[143],"gain":[145],"deeper":[146],"understanding":[147],"subpopulations.":[150]},"counts_by_year":[{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":5}],"updated_date":"2026-05-22T06:13:13.366637","created_date":"2025-10-10T00:00:00"}