{"id":"https://openalex.org/W2112656327","doi":"https://doi.org/10.1136/amiajnl-2012-001119","title":"Comparative analysis of pharmacovigilance methods in the detection of adverse drug reactions using electronic medical records","display_name":"Comparative analysis of pharmacovigilance methods in the detection of adverse drug reactions using electronic medical records","publication_year":2012,"publication_date":"2012-11-18","ids":{"openalex":"https://openalex.org/W2112656327","doi":"https://doi.org/10.1136/amiajnl-2012-001119","mag":"2112656327","pmid":"https://pubmed.ncbi.nlm.nih.gov/23161894"},"language":"en","primary_location":{"id":"doi:10.1136/amiajnl-2012-001119","is_oa":true,"landing_page_url":"https://doi.org/10.1136/amiajnl-2012-001119","pdf_url":"https://academic.oup.com/jamia/article-pdf/20/3/420/17374544/20-3-420.pdf","source":{"id":"https://openalex.org/S129839026","display_name":"Journal of the American Medical Informatics Association","issn_l":"1067-5027","issn":["1067-5027","1527-974X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Medical Informatics Association","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/jamia/article-pdf/20/3/420/17374544/20-3-420.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100347930","display_name":"Mei Liu","orcid":"https://orcid.org/0000-0002-7063-6886"},"institutions":[{"id":"https://openalex.org/I118118575","display_name":"New Jersey Institute of Technology","ror":"https://ror.org/05e74xb87","country_code":"US","type":"education","lineage":["https://openalex.org/I118118575"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. Liu","raw_affiliation_strings":["Department of Computer Science, New Jersey Institute of Technology, Newark, New Jersey, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, New Jersey Institute of Technology, Newark, New Jersey, USA","institution_ids":["https://openalex.org/I118118575"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082303665","display_name":"Eugenia McPeek Hinz","orcid":"https://orcid.org/0000-0003-3759-9806"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"E. R. McPeek Hinz","raw_affiliation_strings":["Department of Biomedical Informatics, School of Medicine, Vanderbilt University, Nashville, Tennessee, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Informatics, School of Medicine, Vanderbilt University, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011689338","display_name":"Michael E. Matheny","orcid":"https://orcid.org/0000-0003-3217-4147"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I4210101790","display_name":"VA Tennessee Valley Healthcare System","ror":"https://ror.org/01c9rqr26","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210101790","https://openalex.org/I4210112672"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. E. Matheny","raw_affiliation_strings":["Department of Biomedical Informatics, School of Medicine, Vanderbilt University, Nashville, Tennessee, USA","Geriatric Research, Education and Clinical Care, Veterans Health Administration, Tennessee Valley Healthcare System, Nashville, Tennessee, USA","Department of Biostatistics, School of Medicine, Vanderbilt University, Nashville, Tennessee, USA","Division of General Internal Medicine, School of Medicine, Vanderbilt University, Nashville, Tennessee, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Informatics, School of Medicine, Vanderbilt University, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"Geriatric Research, Education and Clinical Care, Veterans Health Administration, Tennessee Valley Healthcare System, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I4210101790"]},{"raw_affiliation_string":"Department of Biostatistics, School of Medicine, Vanderbilt University, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"Division of General Internal Medicine, School of Medicine, Vanderbilt University, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070908224","display_name":"Joshua C. Denny","orcid":"https://orcid.org/0000-0002-3049-7332"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. C. Denny","raw_affiliation_strings":["Department of Biomedical Informatics, School of Medicine, Vanderbilt University, Nashville, Tennessee, USA","Division of General Internal Medicine, School of Medicine, Vanderbilt University, Nashville, Tennessee, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Informatics, School of Medicine, Vanderbilt University, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"Division of General Internal Medicine, School of Medicine, Vanderbilt University, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058793854","display_name":"Jonathan S. Schildcrout","orcid":"https://orcid.org/0000-0003-2276-2551"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I4210101190","display_name":"Cancer Research And Biostatistics","ror":"https://ror.org/01575p865","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210101190"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. S. Schildcrout","raw_affiliation_strings":["Department of Biostatistics,","School of Medicine, Vanderbilt University, Nashville, Tennessee, USA","Department of Biostatistics, School of Medicine, Vanderbilt University, Nashville, Tennessee, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biostatistics,","institution_ids":["https://openalex.org/I4210101190"]},{"raw_affiliation_string":"School of Medicine, Vanderbilt University, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"Department of Biostatistics, School of Medicine, Vanderbilt University, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069987722","display_name":"Randolph A. Miller","orcid":null},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R. A. Miller","raw_affiliation_strings":["Department of Biomedical Informatics, School of Medicine, Vanderbilt University, Nashville, Tennessee, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Informatics, School of Medicine, Vanderbilt University, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113243772","display_name":"Huiqin Xu","orcid":null},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I919571938","display_name":"The University of Texas Health Science Center at Houston","ror":"https://ror.org/03gds6c39","country_code":"US","type":"education","lineage":["https://openalex.org/I919571938"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"H. Xu","raw_affiliation_strings":["Department of Biomedical Informatics, School of Medicine, Vanderbilt University, Nashville, Tennessee, USA","School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Informatics, School of Medicine, Vanderbilt University, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA","institution_ids":["https://openalex.org/I919571938"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5113243772"],"corresponding_institution_ids":["https://openalex.org/I200719446","https://openalex.org/I919571938"],"apc_list":{"value":3967,"currency":"USD","value_usd":3967},"apc_paid":null,"fwci":3.2446,"has_fulltext":true,"cited_by_count":80,"citation_normalized_percentile":{"value":0.92144595,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"20","issue":"3","first_page":"420","last_page":"426"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11943","display_name":"Pharmacovigilance and Adverse Drug Reactions","score":0.9975000023841858,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11943","display_name":"Pharmacovigilance and Adverse Drug Reactions","score":0.9975000023841858,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10845","display_name":"Advanced Causal Inference Techniques","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13720","display_name":"Benford\u2019s Law and Fraud Detection","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pharmacovigilance","display_name":"Pharmacovigilance","score":0.9416994452476501},{"id":"https://openalex.org/keywords/drug-reaction","display_name":"Drug reaction","score":0.7047263979911804},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.6072965860366821},{"id":"https://openalex.org/keywords/medical-record","display_name":"Medical record","score":0.6008636951446533},{"id":"https://openalex.org/keywords/adverse-drug-reaction","display_name":"Adverse drug reaction","score":0.5864680409431458},{"id":"https://openalex.org/keywords/drug","display_name":"Drug","score":0.5687194466590881},{"id":"https://openalex.org/keywords/harm","display_name":"Harm","score":0.4960955083370209},{"id":"https://openalex.org/keywords/medical-emergency","display_name":"Medical emergency","score":0.4679875373840332},{"id":"https://openalex.org/keywords/health-records","display_name":"Health records","score":0.4531481862068176},{"id":"https://openalex.org/keywords/emergency-medicine","display_name":"Emergency medicine","score":0.401143342256546},{"id":"https://openalex.org/keywords/intensive-care-medicine","display_name":"Intensive care medicine","score":0.3431628942489624},{"id":"https://openalex.org/keywords/pharmacology","display_name":"Pharmacology","score":0.27596911787986755},{"id":"https://openalex.org/keywords/health-care","display_name":"Health care","score":0.1569046974182129},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.1266704499721527},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.07659783959388733}],"concepts":[{"id":"https://openalex.org/C57658597","wikidata":"https://www.wikidata.org/wiki/Q1550789","display_name":"Pharmacovigilance","level":3,"score":0.9416994452476501},{"id":"https://openalex.org/C2993432071","wikidata":"https://www.wikidata.org/wiki/Q45959","display_name":"Drug reaction","level":3,"score":0.7047263979911804},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6072965860366821},{"id":"https://openalex.org/C195910791","wikidata":"https://www.wikidata.org/wiki/Q1324077","display_name":"Medical record","level":2,"score":0.6008636951446533},{"id":"https://openalex.org/C2780542314","wikidata":"https://www.wikidata.org/wiki/Q45959","display_name":"Adverse drug reaction","level":3,"score":0.5864680409431458},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.5687194466590881},{"id":"https://openalex.org/C2777363581","wikidata":"https://www.wikidata.org/wiki/Q15098235","display_name":"Harm","level":2,"score":0.4960955083370209},{"id":"https://openalex.org/C545542383","wikidata":"https://www.wikidata.org/wiki/Q2751242","display_name":"Medical emergency","level":1,"score":0.4679875373840332},{"id":"https://openalex.org/C3019952477","wikidata":"https://www.wikidata.org/wiki/Q1324077","display_name":"Health records","level":3,"score":0.4531481862068176},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.401143342256546},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3431628942489624},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.27596911787986755},{"id":"https://openalex.org/C160735492","wikidata":"https://www.wikidata.org/wiki/Q31207","display_name":"Health care","level":2,"score":0.1569046974182129},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1266704499721527},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.07659783959388733},{"id":"https://openalex.org/C50522688","wikidata":"https://www.wikidata.org/wiki/Q189833","display_name":"Economic growth","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C77805123","wikidata":"https://www.wikidata.org/wiki/Q161272","display_name":"Social psychology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011358","descriptor_name":"Product Surveillance, Postmarketing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D011358","descriptor_name":"Product Surveillance, Postmarketing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D011358","descriptor_name":"Product Surveillance, Postmarketing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D057286","descriptor_name":"Electronic Health Records","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057286","descriptor_name":"Electronic Health Records","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057286","descriptor_name":"Electronic Health Records","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D060735","descriptor_name":"Pharmacovigilance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D060735","descriptor_name":"Pharmacovigilance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D060735","descriptor_name":"Pharmacovigilance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064420","descriptor_name":"Drug-Related Side Effects and Adverse Reactions","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D064420","descriptor_name":"Drug-Related Side Effects and Adverse Reactions","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D064420","descriptor_name":"Drug-Related Side Effects and Adverse Reactions","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1136/amiajnl-2012-001119","is_oa":true,"landing_page_url":"https://doi.org/10.1136/amiajnl-2012-001119","pdf_url":"https://academic.oup.com/jamia/article-pdf/20/3/420/17374544/20-3-420.pdf","source":{"id":"https://openalex.org/S129839026","display_name":"Journal of the American Medical Informatics Association","issn_l":"1067-5027","issn":["1067-5027","1527-974X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Medical Informatics Association","raw_type":"journal-article"},{"id":"pmid:23161894","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23161894","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Medical Informatics Association : JAMIA","raw_type":null},{"id":"pmh:oai:europepmc.org:2980676","is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3628053","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1136/amiajnl-2012-001119","is_oa":true,"landing_page_url":"https://doi.org/10.1136/amiajnl-2012-001119","pdf_url":"https://academic.oup.com/jamia/article-pdf/20/3/420/17374544/20-3-420.pdf","source":{"id":"https://openalex.org/S129839026","display_name":"Journal of the American Medical Informatics Association","issn_l":"1067-5027","issn":["1067-5027","1527-974X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Medical Informatics Association","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.5699999928474426}],"awards":[{"id":"https://openalex.org/G1198600006","display_name":null,"funder_award_id":"UL1 RR024975","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G1612602199","display_name":null,"funder_award_id":"T15 LM007450","funder_id":"https://openalex.org/F4320337372","funder_display_name":"U.S. National Library of Medicine"},{"id":"https://openalex.org/G5599486289","display_name":null,"funder_award_id":"1UL1RR024975","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G7316616948","display_name":null,"funder_award_id":"R01 LM007995","funder_id":"https://openalex.org/F4320337372","funder_display_name":"U.S. National Library of Medicine"},{"id":"https://openalex.org/G938386287","display_name":null,"funder_award_id":"R01 CA141307","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320309151","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34"},{"id":"https://openalex.org/F4320313998","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74"},{"id":"https://openalex.org/F4320316438","display_name":"Georgia Clinical and Translational Science Alliance","ror":null},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337372","display_name":"U.S. National Library of Medicine","ror":"https://ror.org/0060t0j89"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2112656327.pdf","grobid_xml":"https://content.openalex.org/works/W2112656327.grobid-xml"},"referenced_works_count":49,"referenced_works":["https://openalex.org/W198972539","https://openalex.org/W1538636913","https://openalex.org/W1555466040","https://openalex.org/W1802900720","https://openalex.org/W1902066699","https://openalex.org/W1969830656","https://openalex.org/W1974051045","https://openalex.org/W1979845492","https://openalex.org/W1981809734","https://openalex.org/W1982525766","https://openalex.org/W1988100739","https://openalex.org/W1999506291","https://openalex.org/W2015487160","https://openalex.org/W2017851316","https://openalex.org/W2022768291","https://openalex.org/W2028155822","https://openalex.org/W2028408848","https://openalex.org/W2035134373","https://openalex.org/W2039594635","https://openalex.org/W2064716383","https://openalex.org/W2068460589","https://openalex.org/W2069160498","https://openalex.org/W2070255966","https://openalex.org/W2072204838","https://openalex.org/W2074911837","https://openalex.org/W2079215577","https://openalex.org/W2084451425","https://openalex.org/W2086355998","https://openalex.org/W2098702751","https://openalex.org/W2103776471","https://openalex.org/W2106618845","https://openalex.org/W2118415328","https://openalex.org/W2123089829","https://openalex.org/W2129687868","https://openalex.org/W2133680018","https://openalex.org/W2137902465","https://openalex.org/W2146229086","https://openalex.org/W2147598330","https://openalex.org/W2147761870","https://openalex.org/W2151916071","https://openalex.org/W2153448880","https://openalex.org/W2160194473","https://openalex.org/W2160976181","https://openalex.org/W2167089172","https://openalex.org/W2331786215","https://openalex.org/W2469752376","https://openalex.org/W2555756618","https://openalex.org/W4243217122","https://openalex.org/W4292550096"],"related_works":["https://openalex.org/W2995438986","https://openalex.org/W2377282230","https://openalex.org/W2403681070","https://openalex.org/W1606297102","https://openalex.org/W2520672216","https://openalex.org/W2026160434","https://openalex.org/W2521950182","https://openalex.org/W2043382072","https://openalex.org/W2765846794","https://openalex.org/W3217755940"],"abstract_inverted_index":{"OBJECTIVE:":[0],"Medication":[1],"safety":[2],"requires":[3],"that":[4,25,197,237],"each":[5],"drug":[6,18,86],"be":[7],"monitored":[8],"throughout":[9],"its":[10],"market":[11],"life":[12],"as":[13,36],"early":[14],"detection":[15],"of":[16,47,66,92,106,155,160,181,214,226],"adverse":[17],"reactions":[19],"(ADRs)":[20],"can":[21,244],"lead":[22],"to":[23,59,79,246],"alerts":[24],"prevent":[26],"patient":[27],"harm.":[28],"Recently,":[29],"electronic":[30],"medical":[31],"records":[32],"(EMRs)":[33],"have":[34],"emerged":[35],"a":[37,77,93,97,137],"valuable":[38],"resource":[39],"for":[40],"pharmacovigilance.":[41],"This":[42],"study":[43,78],"examines":[44],"the":[45,57,90,103,126,146,205,211,222],"use":[46],"retrospective":[48],"medication":[49,242],"orders":[50,243],"and":[51,96,136,170,187,201,231,241,251],"inpatient":[52],"laboratory":[53,82,172,189,239],"results":[54,83],"documented":[55],"in":[56,111],"EMR":[58,67],"identify":[60],"ADRs.":[61,254],"METHODS:":[62],"Using":[63,174],"12":[64],"years":[65],"data":[68],"from":[69],"Vanderbilt":[70],"University":[71],"Medical":[72],"Center":[73],"(VUMC),":[74],"we":[75,177],"designed":[76],"correlate":[80],"abnormal":[81],"with":[84,228],"specific":[85],"administrations":[87],"by":[88],"comparing":[89],"outcomes":[91],"drug-exposed":[94],"group":[95],"matched":[98],"unexposed":[99],"group.":[100],"We":[101,143],"assessed":[102],"relative":[104],"merits":[105],"six":[107],"pharmacovigilance":[108],"measures":[109],"used":[110],"spontaneous":[112],"reporting":[113,117,120],"systems":[114],"(SRSs):":[115],"proportional":[116],"ratio":[118],"(PRR),":[119],"OR":[121],"(ROR),":[122],"Yule's":[123],"Q":[124],"(YULE),":[125],"\u03c7(2)":[127],"test":[128],"(CHI),":[129],"Bayesian":[130],"confidence":[131],"propagation":[132],"neural":[133],"networks":[134],"(BCPNN),":[135],"gamma":[138],"Poisson":[139],"shrinker":[140],"(GPS).":[141],"RESULTS:":[142],"systematically":[144],"evaluated":[145],"methods":[147],"on":[148,192],"two":[149],"independently":[150],"constructed":[151],"reference":[152,194,212],"standard":[153,195,213],"datasets":[154],"drug-event":[156,166,183],"pairs.":[157],"The":[158],"dataset":[159,180],"Yoon":[161,215],"et":[162,216],"al":[163,217],"contained":[164],"470":[165],"pairs":[167,184],"(10":[168],"drugs":[169,186],"47":[171],"abnormalities).":[173,190],"VUMC's":[175],"EMR,":[176],"created":[178],"another":[179],"378":[182],"(nine":[185],"42":[188],"Evaluation":[191],"our":[193],"showed":[196],"CHI,":[198],"ROR,":[199],"PRR,":[200],"YULE":[202],"all":[203],"had":[204,221],"same":[206],"F":[207,224],"score":[208,225],"(62%).":[209],"When":[210],"was":[218],"used,":[219],"ROR":[220],"best":[223],"68%,":[227],"77%":[229],"precision":[230],"61%":[232],"recall.":[233],"CONCLUSIONS:":[234],"Results":[235],"suggest":[236],"EMR-derived":[238],"measurements":[240],"help":[245],"validate":[247],"previously":[248],"reported":[249],"ADRs,":[250],"detect":[252],"new":[253]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":10},{"year":2017,"cited_by_count":11},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":9},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":2}],"updated_date":"2026-07-23T08:03:31.855105","created_date":"2025-10-10T00:00:00"}