{"id":"https://openalex.org/W2106417713","doi":"https://doi.org/10.1136/amiajnl-2012-000935","title":"Drug\u2014drug interaction through molecular structure similarity analysis","display_name":"Drug\u2014drug interaction through molecular structure similarity analysis","publication_year":2012,"publication_date":"2012-05-31","ids":{"openalex":"https://openalex.org/W2106417713","doi":"https://doi.org/10.1136/amiajnl-2012-000935","mag":"2106417713","pmid":"https://pubmed.ncbi.nlm.nih.gov/22647690"},"language":"en","primary_location":{"id":"doi:10.1136/amiajnl-2012-000935","is_oa":true,"landing_page_url":"https://doi.org/10.1136/amiajnl-2012-000935","pdf_url":"https://academic.oup.com/jamia/article-pdf/19/6/1066/17374173/19-6-1066.pdf","source":{"id":"https://openalex.org/S129839026","display_name":"Journal of the American Medical Informatics Association","issn_l":"1067-5027","issn":["1067-5027","1527-974X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Medical Informatics Association","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/jamia/article-pdf/19/6/1066/17374173/19-6-1066.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073659323","display_name":"Santiago Vilar","orcid":"https://orcid.org/0000-0003-2663-4370"},"institutions":[{"id":"https://openalex.org/I200284239","display_name":"Universidade de Santiago de Compostela","ror":"https://ror.org/030eybx10","country_code":"ES","type":"education","lineage":["https://openalex.org/I200284239"]},{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["ES","US"],"is_corresponding":true,"raw_author_name":"Santiago Vilar","raw_affiliation_strings":["Department of Biomedical Informatics, Columbia University Medical Center, New York, NY, USA. qosanti@yahoo.es","Department of Biomedical Informatics, Columbia University Medical Center, New York, USA","Department of Organic Chemistry, University of Santiago de Compostela, Santiago de Compostela, Spain"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Informatics, Columbia University Medical Center, New York, NY, USA. qosanti@yahoo.es","institution_ids":["https://openalex.org/I2799503643"]},{"raw_affiliation_string":"Department of Biomedical Informatics, Columbia University Medical Center, New York, USA","institution_ids":["https://openalex.org/I2799503643"]},{"raw_affiliation_string":"Department of Organic Chemistry, University of Santiago de Compostela, Santiago de Compostela, Spain","institution_ids":["https://openalex.org/I200284239"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043102729","display_name":"Rave Harpaz","orcid":null},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rave Harpaz","raw_affiliation_strings":["Department of Biomedical Informatics, Columbia University Medical Center, New York, USA"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Informatics, Columbia University Medical Center, New York, USA","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070602119","display_name":"Eugenio Uriarte","orcid":"https://orcid.org/0000-0001-6218-2899"},"institutions":[{"id":"https://openalex.org/I200284239","display_name":"Universidade de Santiago de Compostela","ror":"https://ror.org/030eybx10","country_code":"ES","type":"education","lineage":["https://openalex.org/I200284239"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Eugenio Uriarte","raw_affiliation_strings":["Department of Organic Chemistry, University of Santiago de Compostela, Santiago de Compostela, Spain","Department of Organic Chemistry, University of Santiago de Compostela, Santiago de Compostela,  Spain"],"affiliations":[{"raw_affiliation_string":"Department of Organic Chemistry, University of Santiago de Compostela, Santiago de Compostela, Spain","institution_ids":["https://openalex.org/I200284239"]},{"raw_affiliation_string":"Department of Organic Chemistry, University of Santiago de Compostela, Santiago de Compostela,  Spain","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040020657","display_name":"Lourdes Santana","orcid":"https://orcid.org/0000-0001-6056-8253"},"institutions":[{"id":"https://openalex.org/I200284239","display_name":"Universidade de Santiago de Compostela","ror":"https://ror.org/030eybx10","country_code":"ES","type":"education","lineage":["https://openalex.org/I200284239"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Lourdes Santana","raw_affiliation_strings":["Department of Organic Chemistry, University of Santiago de Compostela, Santiago de Compostela, Spain","Department of Organic Chemistry, University of Santiago de Compostela, Santiago de Compostela,  Spain"],"affiliations":[{"raw_affiliation_string":"Department of Organic Chemistry, University of Santiago de Compostela, Santiago de Compostela, Spain","institution_ids":["https://openalex.org/I200284239"]},{"raw_affiliation_string":"Department of Organic Chemistry, University of Santiago de Compostela, Santiago de Compostela,  Spain","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056128255","display_name":"Ra\u00fal Rabad\u00e1n","orcid":"https://orcid.org/0000-0001-7946-9255"},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Raul Rabadan","raw_affiliation_strings":["Department of Biomedical Informatics, Columbia University Medical Center, New York, USA"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Informatics, Columbia University Medical Center, New York, USA","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109277899","display_name":"Carol Friedman","orcid":null},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carol Friedman","raw_affiliation_strings":["Department of Biomedical Informatics, Columbia University Medical Center, New York, USA"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Informatics, Columbia University Medical Center, New York, USA","institution_ids":["https://openalex.org/I2799503643"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5073659323"],"corresponding_institution_ids":["https://openalex.org/I200284239","https://openalex.org/I2799503643"],"apc_list":{"value":3967,"currency":"USD","value_usd":3967},"apc_paid":null,"fwci":9.0462,"has_fulltext":true,"cited_by_count":278,"citation_normalized_percentile":{"value":0.98454378,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"19","issue":"6","first_page":"1066","last_page":"1074"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10274","display_name":"Synthesis and biological activity","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.9812999963760376,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/drug","display_name":"Drug","score":0.7813717126846313},{"id":"https://openalex.org/keywords/similarity","display_name":"Similarity (geometry)","score":0.5697208046913147},{"id":"https://openalex.org/keywords/drug-drug-interaction","display_name":"Drug-drug interaction","score":0.5647715926170349},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.45697009563446045},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.33081185817718506},{"id":"https://openalex.org/keywords/pharmacology","display_name":"Pharmacology","score":0.24405813217163086},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.2290651798248291}],"concepts":[{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.7813717126846313},{"id":"https://openalex.org/C103278499","wikidata":"https://www.wikidata.org/wiki/Q254465","display_name":"Similarity (geometry)","level":3,"score":0.5697208046913147},{"id":"https://openalex.org/C2910466267","wikidata":"https://www.wikidata.org/wiki/Q718753","display_name":"Drug-drug interaction","level":3,"score":0.5647715926170349},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.45697009563446045},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.33081185817718506},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.24405813217163086},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2290651798248291},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D004347","descriptor_name":"Drug Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004347","descriptor_name":"Drug Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004347","descriptor_name":"Drug Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004364","descriptor_name":"Pharmaceutical Preparations","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D004364","descriptor_name":"Pharmaceutical Preparations","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D004364","descriptor_name":"Pharmaceutical Preparations","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D005544","descriptor_name":"Forecasting","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005544","descriptor_name":"Forecasting","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005544","descriptor_name":"Forecasting","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015394","descriptor_name":"Molecular Structure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015394","descriptor_name":"Molecular Structure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015394","descriptor_name":"Molecular Structure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060735","descriptor_name":"Pharmacovigilance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D060735","descriptor_name":"Pharmacovigilance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D060735","descriptor_name":"Pharmacovigilance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D062313","descriptor_name":"Databases, Pharmaceutical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D062313","descriptor_name":"Databases, Pharmaceutical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D062313","descriptor_name":"Databases, Pharmaceutical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064420","descriptor_name":"Drug-Related Side Effects and Adverse Reactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064420","descriptor_name":"Drug-Related Side Effects and Adverse Reactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064420","descriptor_name":"Drug-Related Side Effects and Adverse Reactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1136/amiajnl-2012-000935","is_oa":true,"landing_page_url":"https://doi.org/10.1136/amiajnl-2012-000935","pdf_url":"https://academic.oup.com/jamia/article-pdf/19/6/1066/17374173/19-6-1066.pdf","source":{"id":"https://openalex.org/S129839026","display_name":"Journal of the American Medical Informatics Association","issn_l":"1067-5027","issn":["1067-5027","1527-974X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Medical Informatics Association","raw_type":"journal-article"},{"id":"pmid:22647690","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22647690","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Medical Informatics Association : JAMIA","raw_type":null},{"id":"pmh:oai:europepmc.org:2809480","is_oa":false,"landing_page_url":"http://europepmc.org/articles/PMC3534468","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3534468","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3534468","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"J Am Med Inform Assoc","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1136/amiajnl-2012-000935","is_oa":true,"landing_page_url":"https://doi.org/10.1136/amiajnl-2012-000935","pdf_url":"https://academic.oup.com/jamia/article-pdf/19/6/1066/17374173/19-6-1066.pdf","source":{"id":"https://openalex.org/S129839026","display_name":"Journal of the American Medical Informatics Association","issn_l":"1067-5027","issn":["1067-5027","1527-974X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Medical Informatics Association","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G3998201246","display_name":null,"funder_award_id":"Social","funder_id":"https://openalex.org/F4320338080","funder_display_name":"European Social Fund"}],"funders":[{"id":"https://openalex.org/F4320326655","display_name":"Xunta de Galicia","ror":"https://ror.org/0181xnw06"},{"id":"https://openalex.org/F4320337372","display_name":"U.S. National Library of Medicine","ror":"https://ror.org/0060t0j89"},{"id":"https://openalex.org/F4320338080","display_name":"European Social Fund","ror":"https://ror.org/00k4n6c32"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2106417713.pdf","grobid_xml":"https://content.openalex.org/works/W2106417713.grobid-xml"},"referenced_works_count":40,"referenced_works":["https://openalex.org/W1249047937","https://openalex.org/W1967616514","https://openalex.org/W1979496029","https://openalex.org/W1981636172","https://openalex.org/W1984977206","https://openalex.org/W1988304729","https://openalex.org/W1992821438","https://openalex.org/W1995077739","https://openalex.org/W2017380317","https://openalex.org/W2026447576","https://openalex.org/W2027582327","https://openalex.org/W2053106197","https://openalex.org/W2067643341","https://openalex.org/W2077130682","https://openalex.org/W2079215577","https://openalex.org/W2079842711","https://openalex.org/W2091582819","https://openalex.org/W2098702751","https://openalex.org/W2106618845","https://openalex.org/W2109906713","https://openalex.org/W2117397379","https://openalex.org/W2118415328","https://openalex.org/W2152964734","https://openalex.org/W2153341679","https://openalex.org/W2156077095","https://openalex.org/W2160194473","https://openalex.org/W2162011385","https://openalex.org/W2166388774","https://openalex.org/W2177026622","https://openalex.org/W2200017991","https://openalex.org/W2321631825","https://openalex.org/W2403744365","https://openalex.org/W2413944633","https://openalex.org/W4229779919","https://openalex.org/W4243217122","https://openalex.org/W4244978678","https://openalex.org/W4292550096","https://openalex.org/W4293236771","https://openalex.org/W4294457161","https://openalex.org/W4378951071"],"related_works":["https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W3082755771","https://openalex.org/W2395332729","https://openalex.org/W2407625558","https://openalex.org/W2485789143","https://openalex.org/W2040338448","https://openalex.org/W2415873281","https://openalex.org/W2463344692","https://openalex.org/W4403660838"],"abstract_inverted_index":{"The":[0],"proposed":[1],"methodology":[2],"is":[3,31],"simple,":[4],"efficient,":[5],"allows":[6],"the":[7,17],"investigation":[8],"of":[9,12,19,23],"large":[10],"numbers":[11],"drugs,":[13],"and":[14],"helps":[15],"highlight":[16],"etiology":[18],"DDI.":[20],"A":[21],"database":[22],"58":[24],"403":[25],"predicted":[26],"DDIs":[27],"with":[28],"structural":[29],"evidence":[30],"provided":[32],"as":[33],"an":[34],"open":[35],"resource":[36],"for":[37],"investigators":[38],"seeking":[39],"to":[40],"analyze":[41],"DDIs.":[42]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":26},{"year":2024,"cited_by_count":38},{"year":2023,"cited_by_count":38},{"year":2022,"cited_by_count":37},{"year":2021,"cited_by_count":28},{"year":2020,"cited_by_count":27},{"year":2019,"cited_by_count":16},{"year":2018,"cited_by_count":16},{"year":2017,"cited_by_count":12},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":10},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":7}],"updated_date":"2026-03-14T08:43:22.919905","created_date":"2025-10-10T00:00:00"}