{"id":"https://openalex.org/W3194242188","doi":"https://doi.org/10.1126/scirobotics.abh3328","title":"A fully implantable device for intraperitoneal drug delivery refilled by ingestible capsules","display_name":"A fully implantable device for intraperitoneal drug delivery refilled by ingestible capsules","publication_year":2021,"publication_date":"2021-08-11","ids":{"openalex":"https://openalex.org/W3194242188","doi":"https://doi.org/10.1126/scirobotics.abh3328","mag":"3194242188","pmid":"https://pubmed.ncbi.nlm.nih.gov/34408097"},"language":"en","primary_location":{"id":"doi:10.1126/scirobotics.abh3328","is_oa":false,"landing_page_url":"https://doi.org/10.1126/scirobotics.abh3328","pdf_url":null,"source":{"id":"https://openalex.org/S4210213233","display_name":"Science Robotics","issn_l":"2470-9476","issn":["2470-9476"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315823","host_organization_name":"American Association for the Advancement of Science","host_organization_lineage":["https://openalex.org/P4310315823"],"host_organization_lineage_names":["American Association for the Advancement of Science"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Science Robotics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012955761","display_name":"Veronica Iacovacci","orcid":"https://orcid.org/0000-0002-4052-3581"},"institutions":[{"id":"https://openalex.org/I162290304","display_name":"Scuola Superiore Sant'Anna","ror":"https://ror.org/025602r80","country_code":"IT","type":"education","lineage":["https://openalex.org/I162290304"]},{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]}],"countries":["HK","IT"],"is_corresponding":true,"raw_author_name":"Veronica Iacovacci","raw_affiliation_strings":["BioRobotics Institute, Scuola Superiore Sant\u2019Anna, Piazza Martiri della Libert\u00e0 33, 56127 Pisa, Italy","Department of Excellence in Robotics & AI, Scuola Superiore Sant\u2019Anna, Piazza Martiri della Libert\u00e0 33, 56127 Pisa, Italy","Department of Mechanical and Automation Engineering, Chinese University of Hong Kong, Shatin NT, Hong Kong SAR"],"affiliations":[{"raw_affiliation_string":"BioRobotics Institute, Scuola Superiore Sant\u2019Anna, Piazza Martiri della Libert\u00e0 33, 56127 Pisa, Italy","institution_ids":["https://openalex.org/I162290304"]},{"raw_affiliation_string":"Department of Excellence in Robotics & AI, Scuola Superiore Sant\u2019Anna, Piazza Martiri della Libert\u00e0 33, 56127 Pisa, Italy","institution_ids":["https://openalex.org/I162290304"]},{"raw_affiliation_string":"Department of Mechanical and Automation Engineering, Chinese University of Hong Kong, Shatin NT, Hong Kong SAR","institution_ids":["https://openalex.org/I177725633"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024077682","display_name":"Izadyar Tamadon","orcid":"https://orcid.org/0000-0002-4613-5862"},"institutions":[{"id":"https://openalex.org/I162290304","display_name":"Scuola Superiore Sant'Anna","ror":"https://ror.org/025602r80","country_code":"IT","type":"education","lineage":["https://openalex.org/I162290304"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Izadyar Tamadon","raw_affiliation_strings":["BioRobotics Institute, Scuola Superiore Sant\u2019Anna, Piazza Martiri della Libert\u00e0 33, 56127 Pisa, Italy","Department of Excellence in Robotics & AI, Scuola Superiore Sant\u2019Anna, Piazza Martiri della Libert\u00e0 33, 56127 Pisa, Italy"],"affiliations":[{"raw_affiliation_string":"BioRobotics Institute, Scuola Superiore Sant\u2019Anna, Piazza Martiri della Libert\u00e0 33, 56127 Pisa, Italy","institution_ids":["https://openalex.org/I162290304"]},{"raw_affiliation_string":"Department of Excellence in Robotics & AI, Scuola Superiore Sant\u2019Anna, Piazza Martiri della Libert\u00e0 33, 56127 Pisa, Italy","institution_ids":["https://openalex.org/I162290304"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056475542","display_name":"Emanuele F. Kauffmann","orcid":"https://orcid.org/0000-0001-7634-4844"},"institutions":[{"id":"https://openalex.org/I4210165410","display_name":"Azienda Ospedaliera Universitaria Pisana","ror":"https://ror.org/05xrcj819","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210165410"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Emanuele Federico Kauffmann","raw_affiliation_strings":["Division of General and Transplant Surgery, Azienda Ospedaliera Universitaria Pisana, University of Pisa, Via Paradisa 2, 56124 Pisa, Italy"],"affiliations":[{"raw_affiliation_string":"Division of General and Transplant Surgery, Azienda Ospedaliera Universitaria Pisana, University of Pisa, Via Paradisa 2, 56124 Pisa, Italy","institution_ids":["https://openalex.org/I4210165410"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027007606","display_name":"Stefano Pane","orcid":"https://orcid.org/0000-0002-3740-678X"},"institutions":[{"id":"https://openalex.org/I162290304","display_name":"Scuola Superiore Sant'Anna","ror":"https://ror.org/025602r80","country_code":"IT","type":"education","lineage":["https://openalex.org/I162290304"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Stefano Pane","raw_affiliation_strings":["BioRobotics Institute, Scuola Superiore Sant\u2019Anna, Piazza Martiri della Libert\u00e0 33, 56127 Pisa, Italy","Department of Excellence in Robotics & AI, Scuola Superiore Sant\u2019Anna, Piazza Martiri della Libert\u00e0 33, 56127 Pisa, Italy"],"affiliations":[{"raw_affiliation_string":"BioRobotics Institute, Scuola Superiore Sant\u2019Anna, Piazza Martiri della Libert\u00e0 33, 56127 Pisa, Italy","institution_ids":["https://openalex.org/I162290304"]},{"raw_affiliation_string":"Department of Excellence in Robotics & AI, Scuola Superiore Sant\u2019Anna, Piazza Martiri della Libert\u00e0 33, 56127 Pisa, Italy","institution_ids":["https://openalex.org/I162290304"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007992604","display_name":"Virginia Simoni","orcid":null},"institutions":[{"id":"https://openalex.org/I162290304","display_name":"Scuola Superiore Sant'Anna","ror":"https://ror.org/025602r80","country_code":"IT","type":"education","lineage":["https://openalex.org/I162290304"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Virginia Simoni","raw_affiliation_strings":["BioRobotics Institute, Scuola Superiore Sant\u2019Anna, Piazza Martiri della Libert\u00e0 33, 56127 Pisa, Italy","Department of Excellence in Robotics & AI, Scuola Superiore Sant\u2019Anna, Piazza Martiri della Libert\u00e0 33, 56127 Pisa, Italy"],"affiliations":[{"raw_affiliation_string":"BioRobotics Institute, Scuola Superiore Sant\u2019Anna, Piazza Martiri della Libert\u00e0 33, 56127 Pisa, Italy","institution_ids":["https://openalex.org/I162290304"]},{"raw_affiliation_string":"Department of Excellence in Robotics & AI, Scuola Superiore Sant\u2019Anna, Piazza Martiri della Libert\u00e0 33, 56127 Pisa, Italy","institution_ids":["https://openalex.org/I162290304"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088188421","display_name":"Leonardo Marziale","orcid":"https://orcid.org/0000-0002-5257-8141"},"institutions":[{"id":"https://openalex.org/I162290304","display_name":"Scuola Superiore Sant'Anna","ror":"https://ror.org/025602r80","country_code":"IT","type":"education","lineage":["https://openalex.org/I162290304"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Leonardo Marziale","raw_affiliation_strings":["BioRobotics Institute, Scuola Superiore Sant\u2019Anna, Piazza Martiri della Libert\u00e0 33, 56127 Pisa, Italy","Department of Excellence in Robotics & AI, Scuola Superiore Sant\u2019Anna, Piazza Martiri della Libert\u00e0 33, 56127 Pisa, Italy"],"affiliations":[{"raw_affiliation_string":"BioRobotics Institute, Scuola Superiore Sant\u2019Anna, Piazza Martiri della Libert\u00e0 33, 56127 Pisa, Italy","institution_ids":["https://openalex.org/I162290304"]},{"raw_affiliation_string":"Department of Excellence in Robotics & AI, Scuola Superiore Sant\u2019Anna, Piazza Martiri della Libert\u00e0 33, 56127 Pisa, Italy","institution_ids":["https://openalex.org/I162290304"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037119198","display_name":"Michele Aragona","orcid":"https://orcid.org/0000-0002-5982-7913"},"institutions":[{"id":"https://openalex.org/I108290504","display_name":"University of Pisa","ror":"https://ror.org/03ad39j10","country_code":"IT","type":"education","lineage":["https://openalex.org/I108290504"]},{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]}],"countries":["HK","IT"],"is_corresponding":false,"raw_author_name":"Michele Aragona","raw_affiliation_strings":["Department of Clinical and Experimental Medicine, Section of Metabolic Diseases and Diabetes, University of Pisa, Via Savi 10, 56126 Pisa, Italy","Department of Mechanical and Automation Engineering, Chinese University of Hong Kong, Shatin NT, Hong Kong SAR"],"affiliations":[{"raw_affiliation_string":"Department of Clinical and Experimental Medicine, Section of Metabolic Diseases and Diabetes, University of Pisa, Via Savi 10, 56126 Pisa, Italy","institution_ids":["https://openalex.org/I108290504"]},{"raw_affiliation_string":"Department of Mechanical and Automation Engineering, Chinese University of Hong Kong, Shatin NT, Hong Kong SAR","institution_ids":["https://openalex.org/I177725633"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071784689","display_name":"Luigi Cobuccio","orcid":"https://orcid.org/0000-0002-9859-0998"},"institutions":[{"id":"https://openalex.org/I4210086137","display_name":"Ospedale Cisanello","ror":"https://ror.org/00mc91w09","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210086137","https://openalex.org/I4210165410"]},{"id":"https://openalex.org/I4210165410","display_name":"Azienda Ospedaliera Universitaria Pisana","ror":"https://ror.org/05xrcj819","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210165410"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Luigi Cobuccio","raw_affiliation_strings":["Emergency Surgery Unit, Azienda Ospedaliero Universitaria Pisana Cisanello Hospital, Via Piero Trivella, 56124 Pisa, Italy"],"affiliations":[{"raw_affiliation_string":"Emergency Surgery Unit, Azienda Ospedaliero Universitaria Pisana Cisanello Hospital, Via Piero Trivella, 56124 Pisa, Italy","institution_ids":["https://openalex.org/I4210086137","https://openalex.org/I4210165410"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039819277","display_name":"Massimo Chiarugi","orcid":"https://orcid.org/0000-0001-6905-2499"},"institutions":[{"id":"https://openalex.org/I4210086137","display_name":"Ospedale Cisanello","ror":"https://ror.org/00mc91w09","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210086137","https://openalex.org/I4210165410"]},{"id":"https://openalex.org/I4210165410","display_name":"Azienda Ospedaliera Universitaria Pisana","ror":"https://ror.org/05xrcj819","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210165410"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Massimo Chiarugi","raw_affiliation_strings":["Emergency Surgery Unit, Azienda Ospedaliero Universitaria Pisana Cisanello Hospital, Via Piero Trivella, 56124 Pisa, Italy"],"affiliations":[{"raw_affiliation_string":"Emergency Surgery Unit, Azienda Ospedaliero Universitaria Pisana Cisanello Hospital, Via Piero Trivella, 56124 Pisa, Italy","institution_ids":["https://openalex.org/I4210086137","https://openalex.org/I4210165410"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076392384","display_name":"Paolo Dario","orcid":"https://orcid.org/0000-0001-9489-0056"},"institutions":[{"id":"https://openalex.org/I125839683","display_name":"Beijing Institute of Technology","ror":"https://ror.org/01skt4w74","country_code":"CN","type":"education","lineage":["https://openalex.org/I125839683","https://openalex.org/I890469752"]},{"id":"https://openalex.org/I132806614","display_name":"University of Dubai","ror":"https://ror.org/05h0z7c09","country_code":"AE","type":"education","lineage":["https://openalex.org/I132806614"]},{"id":"https://openalex.org/I162290304","display_name":"Scuola Superiore Sant'Anna","ror":"https://ror.org/025602r80","country_code":"IT","type":"education","lineage":["https://openalex.org/I162290304"]},{"id":"https://openalex.org/I162868743","display_name":"Tianjin University","ror":"https://ror.org/012tb2g32","country_code":"CN","type":"education","lineage":["https://openalex.org/I162868743"]}],"countries":["AE","CN","IT"],"is_corresponding":false,"raw_author_name":"Paolo Dario","raw_affiliation_strings":["Beijing Advanced Innovation Center for Intelligent Robots and Systems, Beijing Institute of Technology, Beijing, China","BioRobotics Institute, Scuola Superiore Sant\u2019Anna, Piazza Martiri della Libert\u00e0 33, 56127 Pisa, Italy","Department of Excellence in Robotics & AI, Scuola Superiore Sant\u2019Anna, Piazza Martiri della Libert\u00e0 33, 56127 Pisa, Italy","Department of Mechanical Engineering, Tianjin University, Tianjin, China","Dubai Future Labs, Dubai, United Arab Emirates"],"affiliations":[{"raw_affiliation_string":"Beijing Advanced Innovation Center for Intelligent Robots and Systems, Beijing Institute of Technology, Beijing, China","institution_ids":["https://openalex.org/I125839683"]},{"raw_affiliation_string":"BioRobotics Institute, Scuola Superiore Sant\u2019Anna, Piazza Martiri della Libert\u00e0 33, 56127 Pisa, Italy","institution_ids":["https://openalex.org/I162290304"]},{"raw_affiliation_string":"Department of Excellence in Robotics & AI, Scuola Superiore Sant\u2019Anna, Piazza Martiri della Libert\u00e0 33, 56127 Pisa, Italy","institution_ids":["https://openalex.org/I162290304"]},{"raw_affiliation_string":"Department of Mechanical Engineering, Tianjin University, Tianjin, China","institution_ids":["https://openalex.org/I162868743"]},{"raw_affiliation_string":"Dubai Future Labs, Dubai, United Arab Emirates","institution_ids":["https://openalex.org/I132806614"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019711625","display_name":"Stefano Del Prato","orcid":"https://orcid.org/0000-0002-5388-0270"},"institutions":[{"id":"https://openalex.org/I108290504","display_name":"University of Pisa","ror":"https://ror.org/03ad39j10","country_code":"IT","type":"education","lineage":["https://openalex.org/I108290504"]},{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]}],"countries":["HK","IT"],"is_corresponding":false,"raw_author_name":"Stefano Del Prato","raw_affiliation_strings":["Department of Clinical and Experimental Medicine, Section of Metabolic Diseases and Diabetes, University of Pisa, Via Savi 10, 56126 Pisa, Italy","Department of Mechanical and Automation Engineering, Chinese University of Hong Kong, Shatin NT, Hong Kong SAR"],"affiliations":[{"raw_affiliation_string":"Department of Clinical and Experimental Medicine, Section of Metabolic Diseases and Diabetes, University of Pisa, Via Savi 10, 56126 Pisa, Italy","institution_ids":["https://openalex.org/I108290504"]},{"raw_affiliation_string":"Department of Mechanical and Automation Engineering, Chinese University of Hong Kong, Shatin NT, Hong Kong SAR","institution_ids":["https://openalex.org/I177725633"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017089951","display_name":"Leonardo Ricotti","orcid":"https://orcid.org/0000-0001-8797-3742"},"institutions":[{"id":"https://openalex.org/I162290304","display_name":"Scuola Superiore Sant'Anna","ror":"https://ror.org/025602r80","country_code":"IT","type":"education","lineage":["https://openalex.org/I162290304"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Leonardo Ricotti","raw_affiliation_strings":["BioRobotics Institute, Scuola Superiore Sant\u2019Anna, Piazza Martiri della Libert\u00e0 33, 56127 Pisa, Italy","Department of Excellence in Robotics & AI, Scuola Superiore Sant\u2019Anna, Piazza Martiri della Libert\u00e0 33, 56127 Pisa, Italy"],"affiliations":[{"raw_affiliation_string":"BioRobotics Institute, Scuola Superiore Sant\u2019Anna, Piazza Martiri della Libert\u00e0 33, 56127 Pisa, Italy","institution_ids":["https://openalex.org/I162290304"]},{"raw_affiliation_string":"Department of Excellence in Robotics & AI, Scuola Superiore Sant\u2019Anna, Piazza Martiri della Libert\u00e0 33, 56127 Pisa, Italy","institution_ids":["https://openalex.org/I162290304"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079397291","display_name":"Fabio Vistoli","orcid":"https://orcid.org/0000-0003-2115-4191"},"institutions":[{"id":"https://openalex.org/I4210165410","display_name":"Azienda Ospedaliera Universitaria Pisana","ror":"https://ror.org/05xrcj819","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210165410"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Fabio Vistoli","raw_affiliation_strings":["Division of General and Transplant Surgery, Azienda Ospedaliera Universitaria Pisana, University of Pisa, Via Paradisa 2, 56124 Pisa, Italy"],"affiliations":[{"raw_affiliation_string":"Division of General and Transplant Surgery, Azienda Ospedaliera Universitaria Pisana, University of Pisa, Via Paradisa 2, 56124 Pisa, Italy","institution_ids":["https://openalex.org/I4210165410"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5048610531","display_name":"Arianna Menciassi","orcid":"https://orcid.org/0000-0001-6348-1081"},"institutions":[{"id":"https://openalex.org/I162290304","display_name":"Scuola Superiore Sant'Anna","ror":"https://ror.org/025602r80","country_code":"IT","type":"education","lineage":["https://openalex.org/I162290304"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Arianna Menciassi","raw_affiliation_strings":["BioRobotics Institute, Scuola Superiore Sant\u2019Anna, Piazza Martiri della Libert\u00e0 33, 56127 Pisa, Italy","Department of Excellence in Robotics & AI, Scuola Superiore Sant\u2019Anna, Piazza Martiri della Libert\u00e0 33, 56127 Pisa, Italy"],"affiliations":[{"raw_affiliation_string":"BioRobotics Institute, Scuola Superiore Sant\u2019Anna, Piazza Martiri della Libert\u00e0 33, 56127 Pisa, Italy","institution_ids":["https://openalex.org/I162290304"]},{"raw_affiliation_string":"Department of Excellence in Robotics & AI, Scuola Superiore Sant\u2019Anna, Piazza Martiri della Libert\u00e0 33, 56127 Pisa, Italy","institution_ids":["https://openalex.org/I162290304"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":14,"corresponding_author_ids":["https://openalex.org/A5012955761","https://openalex.org/A5024077682","https://openalex.org/A5048610531"],"corresponding_institution_ids":["https://openalex.org/I162290304","https://openalex.org/I177725633"],"apc_list":null,"apc_paid":null,"fwci":3.3125,"has_fulltext":false,"cited_by_count":63,"citation_normalized_percentile":{"value":0.9268742,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":"6","issue":"57","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10675","display_name":"Mechanical Circulatory Support Devices","score":0.9850000143051147,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10675","display_name":"Mechanical Circulatory Support Devices","score":0.9850000143051147,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11249","display_name":"Wireless Power Transfer Systems","score":0.9800000190734863,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.9775000214576721,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.5246660709381104},{"id":"https://openalex.org/keywords/drug-delivery","display_name":"Drug delivery","score":0.5018925666809082},{"id":"https://openalex.org/keywords/drug","display_name":"Drug","score":0.41095227003097534},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.16652125120162964},{"id":"https://openalex.org/keywords/pharmacology","display_name":"Pharmacology","score":0.15774989128112793},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.14353719353675842}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5246660709381104},{"id":"https://openalex.org/C2779820397","wikidata":"https://www.wikidata.org/wiki/Q1392806","display_name":"Drug delivery","level":2,"score":0.5018925666809082},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.41095227003097534},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.16652125120162964},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.15774989128112793},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.14353719353675842}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D002102","descriptor_name":"Cadaver","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002102","descriptor_name":"Cadaver","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002102","descriptor_name":"Cadaver","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002214","descriptor_name":"Capsules","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002214","descriptor_name":"Capsules","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002214","descriptor_name":"Capsules","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004867","descriptor_name":"Equipment Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004867","descriptor_name":"Equipment Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004867","descriptor_name":"Equipment Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006706","descriptor_name":"Homeostasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006706","descriptor_name":"Homeostasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006706","descriptor_name":"Homeostasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007328","descriptor_name":"Insulin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007328","descriptor_name":"Insulin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007328","descriptor_name":"Insulin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007332","descriptor_name":"Insulin Infusion Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007332","descriptor_name":"Insulin Infusion Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007332","descriptor_name":"Insulin Infusion Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008280","descriptor_name":"Magnetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008280","descriptor_name":"Magnetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008280","descriptor_name":"Magnetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010537","descriptor_name":"Peritoneum","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D010537","descriptor_name":"Peritoneum","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D010537","descriptor_name":"Peritoneum","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D012371","descriptor_name":"Robotics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012371","descriptor_name":"Robotics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012371","descriptor_name":"Robotics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015195","descriptor_name":"Drug Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015195","descriptor_name":"Drug Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015195","descriptor_name":"Drug Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015918","descriptor_name":"Infusion Pumps, Implantable","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015918","descriptor_name":"Infusion Pumps, Implantable","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015918","descriptor_name":"Infusion Pumps, Implantable","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016503","descriptor_name":"Drug Delivery Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016503","descriptor_name":"Drug Delivery Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016503","descriptor_name":"Drug Delivery Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019736","descriptor_name":"Prostheses and Implants","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019736","descriptor_name":"Prostheses and Implants","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019736","descriptor_name":"Prostheses and Implants","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020342","descriptor_name":"Finite Element Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020342","descriptor_name":"Finite Element Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020342","descriptor_name":"Finite Element Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1126/scirobotics.abh3328","is_oa":false,"landing_page_url":"https://doi.org/10.1126/scirobotics.abh3328","pdf_url":null,"source":{"id":"https://openalex.org/S4210213233","display_name":"Science Robotics","issn_l":"2470-9476","issn":["2470-9476"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315823","host_organization_name":"American Association for the Advancement of Science","host_organization_lineage":["https://openalex.org/P4310315823"],"host_organization_lineage_names":["American Association for the Advancement of Science"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Science Robotics","raw_type":"journal-article"},{"id":"pmid:34408097","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34408097","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Science robotics","raw_type":null},{"id":"pmh:oai:arpi.unipi.it:11568/1136610","is_oa":false,"landing_page_url":"http://hdl.handle.net/11568/1136610","pdf_url":null,"source":{"id":"https://openalex.org/S4377196265","display_name":"CINECA IRIS Institutial research information system (University of Pisa)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I108290504","host_organization_name":"University of Pisa","host_organization_lineage":["https://openalex.org/I108290504"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:www.iris.sssup.it:11382/539751","is_oa":false,"landing_page_url":"http://hdl.handle.net/11382/539751","pdf_url":null,"source":{"id":"https://openalex.org/S4377196376","display_name":"CINECA IRIS Institutional Research Information System (Sant'Anna School of Advanced Studies)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I162290304","host_organization_name":"Scuola Superiore Sant'Anna","host_organization_lineage":["https://openalex.org/I162290304"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.5199999809265137,"display_name":"Good health and well-being"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":34,"referenced_works":["https://openalex.org/W1522893511","https://openalex.org/W1587890193","https://openalex.org/W2003735994","https://openalex.org/W2019643737","https://openalex.org/W2056555453","https://openalex.org/W2068823574","https://openalex.org/W2080398194","https://openalex.org/W2110065276","https://openalex.org/W2110545851","https://openalex.org/W2111555794","https://openalex.org/W2116427719","https://openalex.org/W2150844040","https://openalex.org/W2154175915","https://openalex.org/W2160400740","https://openalex.org/W2337641304","https://openalex.org/W2559177329","https://openalex.org/W2563731157","https://openalex.org/W2574063486","https://openalex.org/W2598070036","https://openalex.org/W2620745696","https://openalex.org/W2784002692","https://openalex.org/W2787690100","https://openalex.org/W2788331089","https://openalex.org/W2793066764","https://openalex.org/W2883428425","https://openalex.org/W2903220880","https://openalex.org/W2909932688","https://openalex.org/W2913582983","https://openalex.org/W2941460562","https://openalex.org/W2979525595","https://openalex.org/W2991598122","https://openalex.org/W3030378837","https://openalex.org/W3107183525","https://openalex.org/W3139540107"],"related_works":["https://openalex.org/W2748952813","https://openalex.org/W3031052312","https://openalex.org/W4389568370","https://openalex.org/W3032375762","https://openalex.org/W1995515455","https://openalex.org/W2080531066","https://openalex.org/W2586801360","https://openalex.org/W3108674512","https://openalex.org/W1506200166","https://openalex.org/W2993762413"],"abstract_inverted_index":{"Creating":[0],"fully":[1,97],"implantable":[2,72,98,221],"robots":[3],"that":[4,182,191],"replace":[5],"or":[6],"restore":[7],"physiological":[8],"processes":[9],"is":[10,27,47,125,209],"a":[11,75,96,114,128,137,142],"great":[12],"challenge":[13],"in":[14,21,30,74,83,188,200],"medical":[15],"robotics.":[16],"Restoring":[17],"blood":[18,193],"glucose":[19,194],"homeostasis":[20],"patients":[22],"with":[23,219],"type":[24,38],"1":[25,39],"diabetes":[26,40],"particularly":[28],"interesting":[29],"this":[31,155],"sense.":[32],"Intraperitoneal":[33,94],"insulin":[34],"delivery":[35],"could":[36,79],"revolutionize":[37],"treatment.":[41],"At":[42],"present,":[43],"the":[44,66,110,147,151,159,173,177,183,192,225],"intraperitoneal":[45,57,84,120],"route":[46],"little":[48],"used":[49],"because":[50],"it":[51],"relies":[52],"on":[53,127],"accessing":[54],"ports":[55],"connecting":[56],"catheters":[58],"to":[59,69,145,230],"external":[60],"reservoirs.":[61],"Drug-loaded":[62],"pills":[63,105],"transported":[64],"across":[65],"digestive":[67],"system":[68,117],"refill":[70],"an":[71],"reservoir":[73,231],"minimally":[76],"invasive":[77],"fashion":[78],"open":[80],"new":[81],"possibilities":[82],"delivery.":[85,121],"Here,":[86],"we":[87,157],"describe":[88,158],"PILLSID":[89,160],"(PILl-refiLled":[90],"implanted":[91],"System":[92],"for":[93,118],"Delivery),":[95],"robotic":[99,123],"device":[100,111,124,163,175,204],"refillable":[101],"through":[102],"ingestible":[103],"magnetic":[104,131],"carrying":[106],"drugs.":[107],"Once":[108],"refilled,":[109],"acts":[112],"as":[113,168],"programmable":[115],"microinfusion":[116],"precise":[119],"The":[122,162,203],"grounded":[126],"combination":[129],"of":[130],"switchable":[132],"components,":[133],"miniaturized":[134],"mechatronic":[135],"elements,":[136],"wireless":[138],"powering":[139],"system,":[140],"and":[141,149,171,190,208,233],"control":[143,150],"unit":[144],"implement":[146],"refilling":[148,184,232],"infusion":[152],"processes.":[153],"In":[154],"study,":[156],"prototyping.":[161],"key":[164],"blocks":[165],"are":[166],"validated":[167],"single":[169],"components":[170],"within":[172],"integrated":[174],"at":[176],"preclinical":[178],"level.":[179],"We":[180],"demonstrate":[181],"mechanism":[185],"works":[186],"efficiently":[187],"vivo":[189],"level":[195],"can":[196],"be":[197],"safely":[198],"regulated":[199],"diabetic":[201],"swine.":[202],"weights":[205],"165":[206],"grams":[207],"78":[210],"millimeters":[211,214],"by":[212,215],"63":[213],"35":[216],"millimeters,":[217],"comparable":[218],"commercial":[220],"devices":[222],"yet":[223],"overcoming":[224],"urgent":[226],"critical":[227],"issues":[228],"related":[229],"powering.":[234]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":21},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":16},{"year":2022,"cited_by_count":11},{"year":2021,"cited_by_count":2}],"updated_date":"2026-04-18T07:56:08.524223","created_date":"2025-10-10T00:00:00"}